Context Matters: NOTCH Signatures and Pathway in Cancer Progression and Metastasis
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Title
Context Matters: NOTCH Signatures and Pathway in Cancer Progression and Metastasis
Authors
Keywords
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Journal
Cells
Volume 10, Issue 1, Pages 94
Publisher
MDPI AG
Online
2021-01-08
DOI
10.3390/cells10010094
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Note: Only part of the references are listed.- NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis
- (2020) Sarah Luiken et al. ONCOGENE
- Pathway and network analysis of more than 2500 whole cancer genomes
- (2020) Matthew A. Reyna et al. Nature Communications
- Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling
- (2020) Sampath K. Loganathan et al. SCIENCE
- The miR-1224-5p/ELF3 Axis Regulates Malignant Behaviors of Pancreatic Cancer via PI3K/AKT/Notch Signaling Pathways
- (2020) Lingming Kong et al. OncoTargets and Therapy
- TWIST1 correlates with Notch signaling pathway to develop esophageal squamous cell carcinoma
- (2020) Yasaman Fahim et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Pharmacological disruption of the Notch transcription factor complex
- (2020) Rajwinder Lehal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pan-cancer analysis of the developmental pathways reveals non-canonical wnt signaling as a driver of mesenchymal-type tumors
- (2020) Andrew G. Xue et al. Translational Research
- NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation
- (2020) Kai Miao et al. Nature Communications
- Top Notch Targeting Strategies in Cancer: A Detailed Overview of Recent Insights and Current Perspectives
- (2020) Gillian Moore et al. Cells
- The Wnt Signalling Pathway: A Tailored Target in Cancer
- (2020) Malvina Koni et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Intra-Tumoral Angiogenesis Is Associated with Inflammation, Immune Reaction and Metastatic Recurrence in Breast Cancer
- (2020) Masanori Oshi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mutations in the notch signalling pathway are associated with enhanced anti‐tumour immunity in colorectal cancer
- (2020) Fei Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Isoflurane promotes epithelial-to-mesenchymal transition and metastasis of bladder cancer cells through HIF-1α-β-catenin/Notch1 pathways
- (2020) Na Lu et al. LIFE SCIENCES
- Association between tumor mutation profile and clinical outcomes among Hispanic Latina women with triple-negative breast cancer
- (2020) Alexander Philipovskiy et al. PLoS One
- Regulation of epithelial-mesenchymal transition and organoid morphogenesis by a novel TGFβ-TCF7L2 isoform-specific signaling pathway
- (2020) Kunal Karve et al. Cell Death & Disease
- Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1
- (2020) Huimin Jiang et al. Nature Communications
- Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis
- (2020) Nan W. Hultgren et al. Nature Communications
- Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells
- (2020) Cinzia Donato et al. Cell Reports
- IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation
- (2020) Li Pan et al. eLife
- Oncogenic and Tumor-Suppressive Functions of NOTCH Signaling in Glioma
- (2020) Elena Parmigiani et al. Cells
- Blockade of a laminin-411 - Notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment crosstalk
- (2019) Tao Sun et al. CANCER RESEARCH
- Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy
- (2019) Patrick Carlson et al. NATURE CELL BIOLOGY
- Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition
- (2019) Arnaud Augert et al. Science Signaling
- Neutrophils escort circulating tumour cells to enable cell cycle progression
- (2019) Barbara Maria Szczerba et al. NATURE
- Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
- (2019) Jelena Petrovic et al. MOLECULAR CELL
- miR-195-5p/NOTCH2-mediated EMT modulates IL-4 secretion in colorectal cancer to affect M2-like TAM polarization
- (2019) Xiaobin Lin et al. Journal of Hematology & Oncology
- MAML1 regulates EMT markers expression through NOTCH-independent pathway in breast cancer cell line MCF7
- (2019) Seyedeh Mahya Shariat Razavi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Estrogen receptor α-NOTCH1 axis enhances basal stem-like cells and epithelial-mesenchymal transition phenotypes in prostate cancer
- (2019) Yongmei Shen et al. Cell Communication and Signaling
- Metastasis is impaired by endothelial-specific Dll4 loss-of-function through inhibition of epithelial-to-mesenchymal transition and reduction of cancer stem cells and circulating tumor cells
- (2019) Liliana Mendonça et al. CLINICAL & EXPERIMENTAL METASTASIS
- PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling
- (2019) Marc L. Sprouse et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Non-canonical Notch Signaling Regulates Actin Remodeling in Cell Migration by Activating PI3K/AKT/Cdc42 Pathway
- (2019) Lei Liu et al. Frontiers in Pharmacology
- Aberrations in Notch-Hedgehog signalling reveal cancer stem cells harbouring conserved oncogenic properties associated with hypoxia and immunoevasion
- (2019) Wai Hoong Chang et al. BRITISH JOURNAL OF CANCER
- Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
- (2019) Rene Jackstadt et al. CANCER CELL
- Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains colorectal cancer progression and chemoresistance
- (2019) Maria Pelullo et al. CANCER RESEARCH
- Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state
- (2019) Kosuke Mizukoshi et al. INTERNATIONAL JOURNAL OF CANCER
- Notch1 signaling pathway promotes invasion, self-renewal and growth of glioma initiating cells via modulating chemokine system CXCL12/CXCR4
- (2019) Li Yi et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient Samples
- (2019) Sally E. Trabucco et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Expression Profiling of Circulating Tumor Cells in Pancreatic Ductal Adenocarcinoma Patients: Biomarkers Predicting Overall Survival
- (2019) Consuelo Amantini et al. Frontiers in Oncology
- Notch pathway: a bistable inducer of biological noise?
- (2019) Filip Vujovic et al. Cell Communication and Signaling
- Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress
- (2019) Nicole C. A. van Engeland et al. Scientific Reports
- Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines
- (2018) L. Gelsomino et al. CANCER LETTERS
- Dynamic Ligand Discrimination in the Notch Signaling Pathway
- (2018) Nagarajan Nandagopal et al. CELL
- A highlight on Sonic hedgehog pathway
- (2018) Gabriela Basile Carballo et al. Cell Communication and Signaling
- Notch signalling induces epithelial‑mesenchymal transition to promote metastasis in oral squamous cell carcinoma
- (2018) Jianping Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma
- (2018) Alex KleinJan et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Inhibition of Notch signaling pathway enhanced the radiosensitivity of breast cancer cells
- (2018) Jian-Heng Peng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The NOTCH Pathway in Head and Neck Squamous Cell Carcinoma
- (2018) T. Fukusumi et al. JOURNAL OF DENTAL RESEARCH
- Notch signaling molecule is involved in the invasion of MiaPaCa2 cells induced by CoCl2 via regulating epithelial‑mesenchymal transition
- (2018) Ding‑Wei Chen et al. Molecular Medicine Reports
- Notch signaling promotes a HIF2α-driven hypoxic response in multiple tumor cell types
- (2018) Anders P. Mutvei et al. ONCOGENE
- HEY1 is expressed independent of NOTCH1 and is associated with poor prognosis in head and neck squamous cell carcinoma
- (2018) Eleni M. Rettig et al. ORAL ONCOLOGY
- Mechanosensitivity of Jagged–Notch signaling can induce a switch-type behavior in vascular homeostasis
- (2018) Sandra Loerakker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche
- (2018) Rumela Chakrabarti et al. SCIENCE
- Differentiation-inducing therapeutic effect of Notch inhibition in reversing malignant transformation of liver normal stem cells via MET
- (2018) Hao Luo et al. Oncotarget
- Targeting the Notch1 oncogene by miR-139-5p inhibits glioma metastasis and epithelial-mesenchymal transition (EMT)
- (2018) Jianlong Li et al. BMC Neurology
- Loss of Notch1 predisposes oro-esophageal epithelium to tumorigenesis
- (2018) Wanlada Sawangarun et al. EXPERIMENTAL CELL RESEARCH
- FBXW7: a critical tumor suppressor of human cancers
- (2018) Chien-Hung Yeh et al. Molecular Cancer
- Overexpression of Epsin�3 enhances migration and invasion of glioma cells by inducing epithelial‑mesenchymal transition
- (2018) Yaru Wang et al. ONCOLOGY REPORTS
- Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia
- (2018) Maurizio Mangolini et al. Nature Communications
- Membrane‐tethered Notch1 exhibits oncogenic property via activation of EGFR–PI3K–AKT pathway in oral squamous cell carcinoma
- (2018) Yang Zheng et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Discovery of a ZIP7 inhibitor from a Notch pathway screen
- (2018) Erin Nolin et al. Nature Chemical Biology
- Toward understanding cancer stem cell heterogeneity in the tumor microenvironment
- (2018) Federico Bocci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro
- (2018) Lena Tveriakhina et al. eLife
- Notch and its oncogenic activity in human malignancies
- (2017) Marlena Brzozowa-Zasada et al. European Surgery-Acta Chirurgica Austriaca
- miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT
- (2017) Jia Chen et al. EXPERIMENTAL CELL RESEARCH
- Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure
- (2017) Kota Fujiki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer
- (2017) Shazia Irshad et al. JOURNAL OF PATHOLOGY
- Spatio-Temporal Genomic Heterogeneity, Phylogeny, and Metastatic Evolution in Salivary Adenoid Cystic Carcinoma
- (2017) Bin Liu et al. JNCI-Journal of the National Cancer Institute
- Numb prevents a complete epithelial–mesenchymal transition by modulating Notch signalling
- (2017) Federico Bocci et al. Journal of the Royal Society Interface
- Factors involved in cancer metastasis: a better understanding to “seed and soil” hypothesis
- (2017) Qiang Liu et al. Molecular Cancer
- MiR-182 promotes cancer invasion by linking RET oncogene activated NF-κB to loss of the HES1/Notch1 regulatory circuit
- (2017) Alf Spitschak et al. Molecular Cancer
- Interference of Notch 1 inhibits the proliferation and invasion of breast cancer cells: Involvement of the β‑catenin signaling pathway
- (2017) Xi Lai et al. Molecular Medicine Reports
- Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
- (2017) Jing Shan Lim et al. NATURE
- Selective regulation of Notch ligands during angiogenesis is mediated by vimentin
- (2017) Daniel Antfolk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Breast tumor cell-specific knockout ofTwist1inhibits cancer cell plasticity, dissemination, and lung metastasis in mice
- (2017) Yixiang Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity
- (2017) Vincent C. Luca et al. SCIENCE
- Mesenchymal Stem Cell Migration and Proliferation Are Mediated by Hypoxia-Inducible Factor-1α Upstream of Notch and SUMO Pathways
- (2017) María Ciria et al. STEM CELLS AND DEVELOPMENT
- Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma
- (2017) Mitsuteru Natsuizaka et al. Nature Communications
- Prognostic roles of Notch receptor mRNA expression in human ovarian cancer
- (2017) Chuan Chen et al. Oncotarget
- Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth
- (2017) Chern Ein Oon et al. Oncotarget
- Spatio-Temporal Genomic Heterogeneity, Phylogeny, and Metastatic Evolution in Salivary Adenoid Cystic Carcinoma
- (2017) Bin Liu et al. JNCI-Journal of the National Cancer Institute
- Prognostic and clinicopathological value of Twist expression in breast cancer: A meta-analysis
- (2017) Weiqiang Qiao et al. PLoS One
- Rationally co-targeting divergent pathways in KRAS wild-type colorectal cancers by CANscript technology reveals tumor dependence on Notch and Erbb2
- (2017) Nilesh Brijwani et al. Scientific Reports
- MicroRNA-449a deficiency promotes colon carcinogenesis
- (2017) Masanori Niki et al. Scientific Reports
- Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma
- (2016) Syed A. Ali et al. CANCER CELL
- Notch: A multi-functional integrating system of microenvironmental signals
- (2016) Bryce LaFoya et al. DEVELOPMENTAL BIOLOGY
- Twist induces epithelial-mesenchymal transition and cell motility in breast cancer via ITGB1-FAK/ILK signaling axis and its associated downstream network
- (2016) Jiajia Yang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis
- (2016) Wantae Kim et al. JOURNAL OF CLINICAL INVESTIGATION
- Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype
- (2016) Marcelo Boareto et al. Journal of the Royal Society Interface
- HER2 expression identifies dynamic functional states within circulating breast cancer cells
- (2016) Nicole Vincent Jordan et al. NATURE
- Twist1 promotes breast cancer invasion and metastasis by silencing Foxa1 expression
- (2016) Y Xu et al. ONCOGENE
- Molecular and proteomic insight into Notch1 characterization in hepatocellular carcinoma
- (2016) Catia Giovannini et al. Oncotarget
- Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer
- (2016) Pawan Upadhyay et al. Oncotarget
- Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer
- (2016) Rae-Kwon Kim et al. Oncotarget
- The Vascular Notch Ligands Delta-Like Ligand 4 (DLL4) and Jagged1 (JAG1) Have Opposing Correlations with Microvascularization but a Uniform Prognostic Effect in Primary Glioblastoma: A Preliminary Study
- (2016) Xian-xin Qiu et al. World Neurosurgery
- Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway
- (2016) Yifan Wang et al. Scientific Reports
- A humanized anti-DLL4 antibody promotes dysfunctional angiogenesis and inhibits breast tumor growth
- (2016) Xuelian Jia et al. Scientific Reports
- Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation
- (2016) Jeanine Pignatelli et al. Scientific Reports
- A Tumor Suppressor Function for Notch Signaling in Forebrain Tumor Subtypes
- (2015) Claudio Giachino et al. CANCER CELL
- Squamousness: Next-generation sequencing reveals shared molecular features across squamous tumor types
- (2015) Maria Schwaederle et al. CELL CYCLE
- Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer
- (2015) Alexander W. Fender et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Notch1 signaling regulates the epithelial–mesenchymal transition and invasion of breast cancer in a Slug-dependent manner
- (2015) Shan Shao et al. Molecular Cancer
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas
- (2015) NEW ENGLAND JOURNAL OF MEDICINE
- Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer
- (2015) S-J Kim et al. ONCOGENE
- Jagged mediates differences in normal and tumor angiogenesis by affecting tip-stalk fate decision
- (2015) Marcelo Boareto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer
- (2015) Sandra Schmitz et al. Oncotarget
- Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance
- (2015) Andre Luiz Vettore et al. Genome Medicine
- Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration
- (2015) David P. A. Cohen et al. PLoS Computational Biology
- Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
- (2015) Mohit Kumar Jolly Frontiers in Oncology
- Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma
- (2015) Kathleen M. Capaccione et al. Oncotarget
- Notch Activation as a Driver of Osteogenic Sarcoma
- (2014) Jianning Tao et al. CANCER CELL
- Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
- (2014) Nicola Aceto et al. CELL
- Integrative and Comparative Genomic Analysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas
- (2014) Tanguy Y. Seiwert et al. CLINICAL CANCER RESEARCH
- NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells
- (2014) Di Zhao et al. JOURNAL OF CLINICAL INVESTIGATION
- NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
- (2014) Andrew P. South et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Genetic landscape of esophageal squamous cell carcinoma
- (2014) Yi-Bo Gao et al. NATURE GENETICS
- A new tumor suppressor role for the Notch pathway in bladder cancer
- (2014) Theodoros Rampias et al. NATURE MEDICINE
- Notch-1 Signaling Promotes the Malignant Features of Human Breast Cancer through NF-κB Activation
- (2014) Li Li et al. PLoS One
- Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut
- (2014) Maia Chanrion et al. Nature Communications
- A Snail1/Notch1 signalling axis controls embryonic vascular development
- (2014) Zhao-Qiu Wu et al. Nature Communications
- Crosstalk of Oncogenic Signaling Pathways during Epithelial–Mesenchymal Transition
- (2014) Stephan Lindsey et al. Frontiers in Oncology
- Activation of the NOTCH Pathway in Head and Neck Cancer
- (2013) W. Sun et al. CANCER RESEARCH
- Bone Marrow-Derived CD11b+Jagged2+ Cells Promote Epithelial-to-Mesenchymal Transition and Metastasization in Colorectal Cancer
- (2013) F. Caiado et al. CANCER RESEARCH
- Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
- (2013) Begoña Díaz et al. JOURNAL OF CELL BIOLOGY
- Small molecules intercept Notch signaling and the early secretory pathway
- (2013) Andreas Krämer et al. Nature Chemical Biology
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- Integrative Genomic Characterization of Oral Squamous Cell Carcinoma Identifies Frequent Somatic Drivers
- (2013) C. R. Pickering et al. Cancer Discovery
- Mitotic and mitogenic Wnt signalling
- (2012) Christof Niehrs et al. EMBO JOURNAL
- Molecular signatures database (MSigDB) 3.0
- (2011) A. Liberzon et al. BIOINFORMATICS
- Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling
- (2011) Masahiro Sonoshita et al. CANCER CELL
- Activation of Notch-1 enhances epithelial-mesenchymal transition in gefitinib-acquired resistant lung cancer cells
- (2011) Mian Xie et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Notch post-translationally regulates β-catenin protein in stem and progenitor cells
- (2011) Chulan Kwon et al. NATURE CELL BIOLOGY
- Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells
- (2011) F Xing et al. ONCOGENE
- Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
- (2011) N. J. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch1 Functions as a Tumor Suppressor in a Model of K-ras–Induced Pancreatic Ductal Adenocarcinoma
- (2010) Linda Hanlon et al. CANCER RESEARCH
- Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
- (2010) M. Fischer et al. CANCER RESEARCH
- The Notch Target Hes1 Directly Modulates Gli1 Expression and Hedgehog Signaling: A Potential Mechanism of Therapeutic Resistance
- (2010) K. C. Schreck et al. CLINICAL CANCER RESEARCH
- Conductin/axin2 and Wnt signalling regulates centrosome cohesion
- (2010) Michel V Hadjihannas et al. EMBO REPORTS
- Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
- (2010) Lars Jakobsson et al. NATURE CELL BIOLOGY
- Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
- (2009) J Chen et al. BRITISH JOURNAL OF CANCER
- Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment
- (2009) Shadmehr Demehri et al. CANCER CELL
- The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
- (2009) Raphael Kopan et al. CELL
- Notch signalling in cancer stem cells
- (2009) Victoria Bolós et al. Clinical & Translational Oncology
- Targeted Knockdown of Notch1 Inhibits Invasion of Human Prostate Cancer Cells Concomitant with Inhibition of Matrix Metalloproteinase-9 and Urokinase Plasminogen Activator
- (2009) B. Bin Hafeez et al. CLINICAL CANCER RESEARCH
- Notch Signaling: The Core Pathway and Its Posttranslational Regulation
- (2009) Mark E. Fortini DEVELOPMENTAL CELL
- Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine
- (2009) S. Fre et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Opposite Effects of Notch-1 and Notch-2 on Mesothelioma Cell Survival under Hypoxia Are Exerted through the Akt Pathway
- (2008) I. Graziani et al. CANCER RESEARCH
- Slug is a direct Notch target required for initiation of cardiac cushion cellularization
- (2008) Kyle Niessen et al. JOURNAL OF CELL BIOLOGY
- Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development
- (2008) F. A. High et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch signaling mediates hypoxia-induced tumor cell migration and invasion
- (2008) C. Sahlgren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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