- Home
- Publications
- Publication Search
- Publication Details
Title
Cytokines in CAR T Cell–Associated Neurotoxicity
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-01-07
DOI
10.3389/fimmu.2020.577027
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Earlier Steroid Use with Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory Large B Cell Lymphoma (R/R LBCL)
- (2020) Max S. Topp et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Risk-Adapted Preemptive Tocilizumab Decreases Severe Cytokine Release Syndrome (CRS) after CTL019 CD19-Targeted Chimeric Antigen Receptor (CAR) T-Cell Therapy for Pediatric B-Cell Acute Lymphoblastic Leukemia (B-ALL)
- (2020) Regina M. Myers et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Tisagenlecleucel Chimeric Antigen Receptor (CAR) T-Cell Therapy for Adults with Diffuse Large B-Cell Lymphoma (DLBCL): Real World Experience from the Center for International Blood & Marrow Transplant Research (CIBMTR) Cellular Therapy (CT) Registry
- (2020) Samantha Jaglowski et al. BLOOD
- Post-Marketing Use Outcomes of an Anti-CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy, Axicabtagene Ciloleucel (Axi-Cel), for the Treatment of Large B Cell Lymphoma (LBCL) in the United States (US)
- (2020) Marcelo C. Pasquini et al. BLOOD
- Single-Cell Transcriptome Atlas of Murine Endothelial Cells
- (2020) Joanna Kalucka et al. CELL
- Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma
- (2020) Jennifer N. Brudno et al. NATURE MEDICINE
- IL (Interleukin)-15 Bridges Astrocyte-Microglia Crosstalk and Exacerbates Brain Injury Following Intracerebral Hemorrhage
- (2020) Samuel X. Shi et al. STROKE
- Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy
- (2020) Alyssa Sheih et al. Nature Communications
- Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation
- (2020) Ankit Jambusaria et al. eLife
- Extracorporeal cytokine removal in severe CAR-T cell associated cytokine release syndrome
- (2020) Klaus Stahl et al. JOURNAL OF CRITICAL CARE
- CRISPR/Cas9-based genome editing in the Era of CAR T cell immunotherapy
- (2019) January Salas-Mckee et al. Human Vaccines & Immunotherapeutics
- Granulocyte-macrophage colony-stimulating factor inactivation in CAR T-Cells prevents monocyte-dependent release of key cytokine release syndrome mediators
- (2019) Mohit Sachdeva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities
- (2019) Xiaoyu Liu et al. IMMUNITY
- Neurological toxicities associated with chimeric antigen receptor T-cell therapy
- (2019) Daniel B Rubin et al. BRAIN
- Glial injury in neurotoxicity after pediatric CD19‐directed chimeric antigen receptor T cell therapy
- (2019) Juliane Gust et al. ANNALS OF NEUROLOGY
- B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma
- (2019) Adam D. Cohen et al. JOURNAL OF CLINICAL INVESTIGATION
- Role and Molecular Mechanisms of Pericytes in Regulation of Leukocyte Diapedesis in Inflamed Tissues
- (2019) Paulina Rudziak et al. MEDIATORS OF INFLAMMATION
- Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma
- (2019) Noopur Raje et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chimeric Antigen Receptor T Cell-Related Neurotoxicity: Mechanisms, Clinical Presentation, and Approach to Treatment
- (2019) Jessica Rice et al. Current Treatment Options in Neurology
- Neuronal vulnerability and multilineage diversity in multiple sclerosis
- (2019) Lucas Schirmer et al. NATURE
- The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells
- (2019) Katrin Mestermann et al. Science Translational Medicine
- Single-cell Analysis of CAR-T Cell Activation Reveals A Mixed TH1/TH2 Response Independent of Differentiation
- (2019) Iva Xhangolli et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- Gamma Interferon Alters Junctional Integrity via Rho Kinase, Resulting in Blood-Brain Barrier Leakage in Experimental Viral Encephalitis
- (2019) Stephanie Bonney et al. mBio
- Tisagenlecleucel Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory Children and Young Adults with Acute Lymphoblastic Leukemia (ALL): Real World Experience from the Center for International Blood and Marrow Transplant Research (CIBMTR) and Cellular Therapy (CT) Registry
- (2019) Stephan Grupp et al. BLOOD
- Adhesion of T Cells to Endothelial Cells Facilitates Blinatumomab-Associated Neurologic Adverse Events
- (2019) Matthias Klinger et al. CANCER RESEARCH
- Long-Term Microgliosis Driven by Acute Systemic Inflammation
- (2019) Alissa Trzeciak et al. JOURNAL OF IMMUNOLOGY
- Mapping microglia states in the human brain through the integration of high-dimensional techniques
- (2019) Roman Sankowski et al. NATURE NEUROSCIENCE
- Preemptive mitigation of CD19 CAR T-cell cytokine release syndrome without attenuation of antileukemic efficacy
- (2019) Rebecca A. Gardner et al. BLOOD
- Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program
- (2019) Laufey Geirsdottir et al. CELL
- EEG Correlates of Delirium in Children and Young Adults With CD19-Directed CAR T Cell Treatment-Related Neurotoxicity
- (2019) Juliane Gust et al. JOURNAL OF CLINICAL NEUROPHYSIOLOGY
- The meninges as barriers and facilitators for the movement of fluid, cells and pathogens related to the rodent and human CNS
- (2018) Roy O. Weller et al. ACTA NEUROPATHOLOGICA
- Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells associate with clinical outcomes in NHL
- (2018) John Rossi et al. BLOOD
- Improved CNS exposure to tocilizumab after cerebrospinal fluid compared to intravenous administration in rhesus macaques
- (2018) Anandani Nellan et al. BLOOD
- The controversial origin of pericytes during angiogenesis – Implications for cell-based therapeutic angiogenesis and cell-based therapies
- (2018) Anna Blocki et al. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
- T Cells Genetically Modified to Express an Anti–B-Cell Maturation Antigen Chimeric Antigen Receptor Cause Remissions of Poor-Prognosis Relapsed Multiple Myeloma
- (2018) Jennifer N. Brudno et al. JOURNAL OF CLINICAL ONCOLOGY
- Unique and shared inflammatory profiles of human brain endothelia and pericytes
- (2018) Leon C. D. Smyth et al. Journal of Neuroinflammation
- Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells
- (2018) Margherita Norelli et al. NATURE MEDICINE
- Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
- (2018) Joseph A. Fraietta et al. NATURE MEDICINE
- CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade
- (2018) Theodoros Giavridis et al. NATURE MEDICINE
- Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'
- (2018) David T. Teachey et al. Nature Reviews Clinical Oncology
- EEG findings in CAR T-cell therapy-related encephalopathy
- (2018) Aline Herlopian et al. NEUROLOGY
- Regulation of Body Temperature by the Nervous System
- (2018) Chan Lek Tan et al. NEURON
- Neural Mechanisms of Inflammation-Induced Fever
- (2018) Anders Blomqvist et al. NEUROSCIENTIST
- Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
- (2018) Jae H. Park et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
- (2018) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- FDA Approval Summary: Tocilizumab for Treatment of Chimeric Antigen Receptor T Cell‐Induced Severe or Life‐Threatening Cytokine Release Syndrome
- (2018) Robert Q. Le et al. ONCOLOGIST
- CAR T cell immunotherapy for human cancer
- (2018) Carl H. June et al. SCIENCE
- Clinical and Biologic Correlates of Neurotoxicity Associated with CAR T Cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia (B-ALL)
- (2018) Bianca D. Santomasso et al. Cancer Discovery
- Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain
- (2018) Andrée-Anne Berthiaume et al. Cell Reports
- Endothelial Activation: The Ang/Tie Axis in Sepsis
- (2018) Aleksandra Leligdowicz et al. Frontiers in Immunology
- Beginning the CAR T cell therapy revolution in the US and EU
- (2018) Stephan Grupp Current Research in Translational Medicine
- Neurologic adverse events in patients with relapsed/refractory acute lymphoblastic leukemia treated with blinatumomab: management and mitigating factors
- (2018) Anthony S. Stein et al. ANNALS OF HEMATOLOGY
- Neurotoxicity after CTL019 in a Pediatric and Young Adult Cohort
- (2018) Jacqueline S. Gofshteyn et al. ANNALS OF NEUROLOGY
- Molecular Architecture of the Mouse Nervous System
- (2018) Amit Zeisel et al. CELL
- Systematic Evaluation of Neurotoxicity in Children and Young Adults Undergoing CD22 Chimeric Antigen Receptor T-Cell Therapy
- (2018) Haneen Shalabi et al. JOURNAL OF IMMUNOTHERAPY
- Hemofiltration Successfully Eliminates Severe Cytokine Release Syndrome Following CD19 CAR-T-Cell Therapy
- (2018) Yanfen Liu et al. JOURNAL OF IMMUNOTHERAPY
- Neuropathology of a Case With Fatal CAR T-Cell-Associated Cerebral Edema
- (2018) Matthew Torre et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Angiopoietin/Tie2 axis regulates the age-at-injury cerebrovascular response to traumatic brain injury
- (2018) Thomas R. Brickler et al. JOURNAL OF NEUROSCIENCE
- Innate immune memory in the brain shapes neurological disease hallmarks
- (2018) Ann-Christin Wendeln et al. NATURE
- Microglia in neurodegeneration
- (2018) Suzanne Hickman et al. NATURE NEUROSCIENCE
- Microglia Responses to Pro-inflammatory Stimuli (LPS, IFNγ+TNFα) and Reprogramming by Resolving Cytokines (IL-4, IL-10)
- (2018) Starlee Lively et al. Frontiers in Cellular Neuroscience
- Cerebral Malaria in Mouse and Man
- (2018) Nazanin Ghazanfari et al. Frontiers in Immunology
- ASBMT Consensus Grading for Cytokine Release Syndrome and Neurological Toxicity Associated with Immune Effector Cells
- (2018) Daniel W Lee et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts
- (2018) Rosalie M. Sterner et al. BLOOD
- Plasma Exchange Can Be an Alternative Therapeutic Modality for Severe Cytokine Release Syndrome after Chimeric Antigen Receptor-T Cell Infusion: A Case Report
- (2018) Xia Xiao et al. CLINICAL CANCER RESEARCH
- Neurotoxicity Associated with CD19-Targeted CAR-T Cell Therapies
- (2018) Juliane Gust et al. CNS DRUGS
- Benefit–Risk Assessment of Blinatumomab in the Treatment of Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia
- (2018) Anthony Stein et al. DRUG SAFETY
- Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
- (2018) Timothy R. Hammond et al. IMMUNITY
- A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
- (2018) Wan-Hong Zhao et al. Journal of Hematology & Oncology
- Brain swelling is independent of peripheral plasma cytokine levels in Malawian children with cerebral malaria
- (2018) Visopo Harawa et al. MALARIA JOURNAL
- Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome
- (2018) Verena Staedtke et al. NATURE
- Potential role of CSF cytokine profiles in discriminating infectious from non-infectious CNS disorders
- (2018) Danielle Fortuna et al. PLoS One
- Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response
- (2018) Sara Bachiller et al. Frontiers in Cellular Neuroscience
- Anakinra Therapy for Non-cancer Inflammatory Diseases
- (2018) Giulio Cavalli et al. Frontiers in Pharmacology
- AXICABTAGENE CILOLEUCEL (AXI-CEL; KTE-C19) IN PATIENTS WITH REFRACTORY AGGRESSIVE NON-HODGKIN LYMPHOMAS (NHL): PRIMARY RESULTS OF THE PIVOTAL TRIAL ZUMA-1
- (2017) S.S. Neelapu et al. HEMATOLOGICAL ONCOLOGY
- Mechanisms and Therapeutic Relevance of Neuro-immune Communication
- (2017) Sangeeta S. Chavan et al. IMMUNITY
- Overview of the IL-1 family in innate inflammation and acquired immunity
- (2017) Charles A. Dinarello IMMUNOLOGICAL REVIEWS
- Neurovascular unit crosstalk: Pericytes and astrocytes modify cytokine secretion patterns of brain endothelial cells
- (2017) William A Banks et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Clinical and immunological responses after CD30-specific chimeric antigen receptor–redirected lymphocytes
- (2017) Carlos A. Ramos et al. JOURNAL OF CLINICAL INVESTIGATION
- Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor–Modified T Cells After Failure of Ibrutinib
- (2017) Cameron J. Turtle et al. JOURNAL OF CLINICAL ONCOLOGY
- Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels
- (2017) James N. Kochenderfer et al. JOURNAL OF CLINICAL ONCOLOGY
- Analysis of plasma multiplex cytokines and increased level of IL-10 and IL-1Ra cytokines in febrile seizures
- (2017) Kyungmin Kim et al. Journal of Neuroinflammation
- CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy
- (2017) Terry J Fry et al. NATURE MEDICINE
- Chimeric antigen receptor T-cell therapy — assessment and management of toxicities
- (2017) Sattva S. Neelapu et al. Nature Reviews Clinical Oncology
- Therapeutic targeting of the angiopoietin–TIE pathway
- (2017) Pipsa Saharinen et al. NATURE REVIEWS DRUG DISCOVERY
- Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas
- (2017) Stephen J. Schuster et al. NEW ENGLAND JOURNAL OF MEDICINE
- Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
- (2017) Sattva S. Neelapu et al. NEW ENGLAND JOURNAL OF MEDICINE
- A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
- (2017) Donald M. O’Rourke et al. Science Translational Medicine
- Brain Pericytes As Mediators of Neuroinflammation
- (2017) Justin Rustenhoven et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells
- (2017) Juliane Gust et al. Cancer Discovery
- Cytokines and Chemokines in Cerebral Malaria Pathogenesis
- (2017) Josefine Dunst et al. Frontiers in Cellular and Infection Microbiology
- Comparison of the inflammatory response of brain microvascular and peripheral endothelial cells following infection with Neisseria meningitidis
- (2017) Julia Dick et al. Pathogens and Disease
- 32nd Annual Meeting and Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2017): Part One
- (2017) Journal for ImmunoTherapy of Cancer
- T cells expressing an anti-B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma
- (2016) S. A. Ali et al. BLOOD
- Toxicities of chimeric antigen receptor T cells: recognition and management
- (2016) Jennifer N. Brudno et al. BLOOD
- Autologous T Cells Expressing CD30 Chimeric Antigen Receptors for Relapsed or Refractory Hodgkin Lymphoma: An Open-Label Phase I Trial
- (2016) Chun-Meng Wang et al. CLINICAL CANCER RESEARCH
- A gradient of glucocorticoid sensitivity among helper T cell cytokines
- (2016) Jesus Banuelos et al. CYTOKINE & GROWTH FACTOR REVIEWS
- CSF, blood-brain barrier, and brain drug delivery
- (2016) William M. Pardridge Expert Opinion on Drug Delivery
- CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients
- (2016) Cameron J. Turtle et al. JOURNAL OF CLINICAL INVESTIGATION
- Myeloid cell transmigration across the CNS vasculature triggers IL-1β–driven neuroinflammation during autoimmune encephalomyelitis in mice
- (2016) Sébastien A. Lévesque et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy
- (2016) Fang Chen et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Balancing the immune response in the brain: IL-10 and its regulation
- (2016) Diogo Lobo-Silva et al. Journal of Neuroinflammation
- From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery
- (2016) William A. Banks NATURE REVIEWS DRUG DISCOVERY
- Acute disseminated encephalomyelitis
- (2016) Daniela Pohl et al. NEUROLOGY
- Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
- (2016) Christine E. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of Fulminant Cerebral Edema in Acute Pediatric Encephalitis
- (2016) Shih-Yun Lan et al. Pediatrics and Neonatology
- Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells
- (2016) Lenka V. Hurton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria
- (2016) Sarah J. Higgins et al. Science Translational Medicine
- Immunotherapy of non-Hodgkin’s lymphoma with a defined ratio of CD8 + and CD4 + CD19-specific chimeric antigen receptor–modified T cells
- (2016) Cameron J. Turtle et al. Science Translational Medicine
- Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia
- (2016) D. T. Teachey et al. Cancer Discovery
- Analysis of the brain mural cell transcriptome
- (2016) Liqun He et al. Scientific Reports
- CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia
- (2015) S. L. Maude et al. BLOOD
- The blood-brain barrier in neuroimmunology: Tales of separation and assimilation
- (2015) W.A. Banks BRAIN BEHAVIOR AND IMMUNITY
- Neurological Complications of PCR-ProvenM. pneumoniaeInfections in Children: Prodromal Illness Duration May Reflect Pathogenetic Mechanism
- (2015) Samiah A. Al-Zaidy et al. CLINICAL INFECTIOUS DISEASES
- Pathogenesis of Brain Edema and Investigation into Anti-Edema Drugs
- (2015) Shotaro Michinaga et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molecular pathophysiology of cerebral edema
- (2015) Jesse A Stokum et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells
- (2015) Simon J. O’Carroll et al. Journal of Neuroinflammation
- T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
- (2015) Daniel W Lee et al. LANCET
- Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study
- (2015) Max S Topp et al. LANCET ONCOLOGY
- Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
- (2015) Aoi Shiomi et al. MEDIATORS OF INFLAMMATION
- Astrocyte barriers to neurotoxic inflammation
- (2015) Michael V. Sofroniew NATURE REVIEWS NEUROSCIENCE
- Brain Swelling and Death in Children with Cerebral Malaria
- (2015) Karl B. Seydel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Opposing Roles of Interferon-Gamma on Cells of the Central Nervous System in Autoimmune Neuroinflammation
- (2015) Payton A. Ottum et al. Frontiers in Immunology
- Interferon-γ Safeguards Blood-Brain Barrier during Experimental Autoimmune Encephalomyelitis
- (2014) Chen Ni et al. AMERICAN JOURNAL OF PATHOLOGY
- Macrophage activation syndrome and cytokine-directed therapies
- (2014) Grant S. Schulert et al. BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
- Current concepts in the diagnosis and management of cytokine release syndrome
- (2014) D. W. Lee et al. BLOOD
- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
- (2014) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Therapeutic Role of Anakinra, an Interleukin-1 Receptor Antagonist, in the Management of Secondary Hemophagocytic Lymphohistiocytosis/Sepsis/Multiple Organ Dysfunction/Macrophage Activating Syndrome in Critically Ill Children*
- (2014) Surender Rajasekaran et al. Pediatric Critical Care Medicine
- IL-6 in Inflammation, Immunity, and Disease
- (2014) T. Tanaka et al. Cold Spring Harbor Perspectives in Biology
- Central Nervous System Involvement in Adults with Epidemic Hemolytic Uremic Syndrome
- (2013) M. Wengenroth et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Pegylated IL-10 induces cancer immunity
- (2013) John B. Mumm et al. BIOESSAYS
- IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair
- (2013) Gilad Kunis et al. BRAIN
- A Phase I, Open-Label Study of Siltuximab, an Anti-IL-6 Monoclonal Antibody, in Patients with B-cell Non-Hodgkin Lymphoma, Multiple Myeloma, or Castleman Disease
- (2013) R. Kurzrock et al. CLINICAL CANCER RESEARCH
- A clinicopathological correlation of the expression of the angiopoietin-Tie-2 receptor pathway in the brain of adults with Plasmodium falciparum malaria
- (2013) Panote Prapansilp et al. MALARIA JOURNAL
- Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia
- (2013) David S. Ritchie et al. MOLECULAR THERAPY
- Imaging in sepsis-associated encephalopathy—insights and opportunities
- (2013) Daniel J. Stubbs et al. Nature Reviews Neurology
- Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: Case report
- (2013) F. Leypoldt et al. NEUROLOGY
- Cerebrospinal Fluid Secretion by the Choroid Plexus
- (2013) Helle H. Damkier et al. PHYSIOLOGICAL REVIEWS
- Pathophysiology of cerebral oedema in acute liver failure
- (2013) Teresa R Scott WORLD JOURNAL OF GASTROENTEROLOGY
- Unwinding the von Willebrand factor strings puzzle
- (2012) K. De Ceunynck et al. BLOOD
- Interleukin-6, a Major Cytokine in the Central Nervous System
- (2012) María Erta et al. International Journal of Biological Sciences
- Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
- (2012) Azeb Tadesse Argaw et al. JOURNAL OF CLINICAL INVESTIGATION
- Immune-neural connections: how the immune system's response to infectious agents influences behavior
- (2012) R. H. McCusker et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- OX40 costimulation by a chimeric antigen receptor abrogates CD28 and IL-2 induced IL-10 secretion by redirected CD4+T cells
- (2012) Andreas A. Hombach et al. OncoImmunology
- Role of microglia in CNS inflammation
- (2011) Manuel B. Graeber et al. FEBS LETTERS
- Cytokines and brain excitability
- (2011) Michael A. Galic et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Targeted Therapy With the T-Cell–Engaging Antibody Blinatumomab of Chemotherapy-Refractory Minimal Residual Disease in B-Lineage Acute Lymphoblastic Leukemia Patients Results in High Response Rate and Prolonged Leukemia-Free Survival
- (2011) Max S. Topp et al. JOURNAL OF CLINICAL ONCOLOGY
- Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes and microglia
- (2011) Wenwen Sheng et al. Journal of Neuroinflammation
- Sepsis-associated encephalopathy and its differential diagnosis
- (2010) Emanuele Iacobone et al. CRITICAL CARE MEDICINE
- Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis
- (2010) Theodore J. Iwashyna et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Distinct Clinical and Immunologic Profiles in Severe Malarial Anemia and Cerebral Malaria in Zambia
- (2010) P. E. Thuma et al. JOURNAL OF INFECTIOUS DISEASES
- Marked potentiation of cell swelling by cytokines in ammonia-sensitized cultured astrocytes
- (2010) Kakulavarapu V Rama Rao et al. Journal of Neuroinflammation
- Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema
- (2010) A. S. Thrane et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blockade of IL-15 activity inhibits microglial activation through the NFκB, p38, and ERK1/2 pathways, reducing cytokine and chemokine release
- (2009) Diego Gomez-Nicola et al. GLIA
- The clinical spectrum and immunobiology of parainfectious neuromyelitis optica (Devic) syndromes
- (2009) Johann Sellner et al. JOURNAL OF AUTOIMMUNITY
- Cerebral inflammation contributes to encephalopathy and brain edema in acute liver failure: protective effect of minocycline
- (2009) Wenlei Jiang et al. JOURNAL OF NEUROCHEMISTRY
- Pathogenesis of Thrombotic Microangiopathies
- (2008) X. Long Zheng et al. Annual Review of Pathology-Mechanisms of Disease
- Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura
- (2008) J. E. Sadler BLOOD
- Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease
- (2008) N. Nishimoto et al. BLOOD
- Serum and cerebrospinal fluid levels of cytokines in acute encephalopathy associated with human herpesvirus-6 infection
- (2008) Takashi Ichiyama et al. BRAIN & DEVELOPMENT
- Detachment of Brain Pericytes from the Basal Lamina is Involved in Disruption of the Blood–Brain Barrier Caused by Lipopolysaccharide-Induced Sepsis in Mice
- (2008) Tsuyoshi Nishioku et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective
- (2008) Solomon S Shaftel et al. Journal of Neuroinflammation
- Inflammatory cytokines inhibit ADAMTS13 synthesis in hepatic stellate cells and endothelial cells
- (2008) W. J. CAO et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started