The meninges as barriers and facilitators for the movement of fluid, cells and pathogens related to the rodent and human CNS

The role of brain barriers in fluid movement in the CNS: is there a ‘glymphatic’ system?

(2018) N. Joan Abbott et al.   ACTA NEUROPATHOLOGICA

The “glymphatic” mechanism for solute clearance in Alzheimer’s disease: game changer or unproven speculation?

(2018) Alex J. Smith et al.   FASEB JOURNAL

Medulloblastoma: From Myth to Molecular

(2017) Vijay Ramaswamy et al.   JOURNAL OF CLINICAL ONCOLOGY

The mouse cortical meninges are the site of immune responses to many different pathogens, and are accessible to intravital imaging

(2017) Jonathan A. Coles et al.   METHODS

The whole-genome landscape of medulloblastoma subtypes

(2017) Paul A. Northcott et al.   NATURE

A journey into the brain: insight into how bacterial pathogens cross blood–brain barriers

(2017) Mathieu Coureuil et al.   NATURE REVIEWS MICROBIOLOGY

Editorial: Clearance Pathways for Amyloid-β. Significance for Alzheimer's Disease and Its Therapy

(2017) Roxana O. Carare   Frontiers in Aging Neuroscience

Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development

(2017) Kjeld Møllgård et al.   Scientific Reports

Vascular basement membranes as pathways for the passage of fluid into and out of the brain

(2016) Alan W. J. Morris et al.   ACTA NEUROPATHOLOGICA

Vascular, glial, and lymphatic immune gateways of the central nervous system

(2016) Britta Engelhardt et al.   ACTA NEUROPATHOLOGICA

Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy

(2016) Abby Keable et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neisseriae internalization by epithelial cells is enhanced by TLR2 stimulation

(2016) Deana N. Toussi et al.   MICROBES AND INFECTION

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

(2016) Christian Schläger et al.   NATURE

Neisserial Heparin Binding Antigen (NHBA) Contributes to the Adhesion of Neisseria meningitidis to Human Epithelial Cells

(2016) Irene Vacca et al.   PLoS One

Dilated Perivascular Spaces in the Basal Ganglia Are a Biomarker of Small-Vessel Disease in a Very Elderly Population with Dementia

(2015) T.P. Hansen et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Nuclear trafficking, histone cleavage and induction of apoptosis by the meningococcal App and MspA autotransporters

(2015) Ahmed S. Khairalla et al.   CELLULAR MICROBIOLOGY

Neisseria meningitidisfactor H-binding protein fHbp: a key virulence factor and vaccine antigen

(2015) Kate L Seib et al.   Expert Review of Vaccines

Binding of Complement Factor H to PorB3 and NspA Enhances Resistance of Neisseria meningitidis to Anti-Factor H Binding Protein Bactericidal Activity

(2015) Serena Giuntini et al.   INFECTION AND IMMUNITY

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

White Matter Perivascular Spaces on Magnetic Resonance Imaging

(2015) Andreas Charidimou et al.   STROKE

Normal pio-dural arterial connections

(2015) Pervinder Bhogal et al.   INTERVENTIONAL NEURORADIOLOGY

Outer brain barriers in rat and human development

(2015) Christian B. Brøchner et al.   Frontiers in Neuroscience

The inner CSF–brain barrier: developmentally controlled access to the brain via intercellular junctions

(2015) Sophie Whish et al.   Frontiers in Neuroscience

Cellular and molecular biology ofNeisseria meningitidiscolonization and invasive disease

(2015) Darryl J. Hill et al.   CLINICAL SCIENCE

White Matter Changes in Dementia: Role of Impaired Drainage of Interstitial Fluid

(2014) Roy O. Weller et al.   BRAIN PATHOLOGY

Comment on the topology of mammalian blood–cerebrospinal fluid barrier

(2014) Hartwig Wolburg et al.   NEUROLOGY PSYCHIATRY AND BRAIN RESEARCH

Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models

(2013) Michal Arbel-Ornath et al.   ACTA NEUROPATHOLOGICA

Role of Epidermal Growth Factor Receptor Signaling in the Interaction of Neisseria meningitidis with Endothelial Cells

(2013) Heiko Slanina et al.   INFECTION AND IMMUNITY

In vitroresistance mechanisms ofNeisseria meningitidisagainst neutrophil extracellular traps

(2013) Martin Lappann et al.   MOLECULAR MICROBIOLOGY

Review: Cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy

(2013) R. O. Carare et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The Adhesin Complex Protein (ACP) of Neisseria meningitidis Is a New Adhesin with Vaccine Potential

(2013) M.-C. Hung et al.   mBio

Dual Pili Post-translational Modifications Synergize to Mediate Meningococcal Adherence to Platelet Activating Factor Receptor on Human Airway Cells

(2013) Freda E. C. Jen et al.   PLoS Pathogens

Neisseria gonorrhoeaebreaches the apical junction of polarized epithelial cells for transmigration by activating EGFR

(2012) Vonetta L. Edwards et al.   CELLULAR MICROBIOLOGY

A bacterial siren song: intimate interactions between Neisseria and neutrophils

(2012) Alison K. Criss et al.   NATURE REVIEWS MICROBIOLOGY

Group B Streptococcus Interactions with Human Meningeal Cells and Astrocytes In Vitro

(2012) Khalil Alkuwaity et al.   PLoS One

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

(2011) Cheryl A. Hawkes et al.   ACTA NEUROPATHOLOGICA

We have got you ‘covered’: how the meninges control brain development

(2011) Julie A Siegenthaler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Neisseria meningitidisAdhesin NadA Targets β1 Integrins

(2011) Virginie Nägele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogenic Neisseria Hitchhike on the Uropod of Human Neutrophils

(2011) Niklas Söderholm et al.   PLoS One

Compromise of Brain Tissue Caused by Cortical Venous Reflux of Intracranial Dural Arteriovenous Fistulas

(2011) Kenichi Sato et al.   STROKE

Developmental Stages in Human Embryos: Revised and New Measurements

(2010) Ronan O’Rahilly et al.   CELLS TISSUES ORGANS

Early microglial colonization of the human forebrain and possible involvement in periventricular white-matter injury of preterm infants

(2010) Catherine Verney et al.   JOURNAL OF ANATOMY

Neisseria meningitidis Induces Brain Microvascular Endothelial Cell Detachment from the Matrix and Cleavage of Occludin: A Role for MMP-8

(2010) Alexandra Schubert-Unkmeir et al.   PLoS Pathogens

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models

(2009) Carlos J. Orihuela et al.   JOURNAL OF CLINICAL INVESTIGATION

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

The blood–CSF barrier explained: when development is not immaturity

(2008) Pia A. Johansson et al.   BIOESSAYS

SR-A, MARCO and TLRs Differentially Recognise Selected Surface Proteins from Neisseria meningitidis: an Example of Fine Specificity in Microbial Ligand Recognition by Innate Immune Receptors

(2008) Annette Plüddemann et al.   Journal of Innate Immunity

Integrins mediate adhesion of medulloblastoma cells to tenascin and activate pathways associated with survival and proliferation

(2008) Paul Fiorilli et al.   LABORATORY INVESTIGATION

Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

(2008) R. O. Carare et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY