AAV Targeting of Glial Cell Types in the Central and Peripheral Nervous System and Relevance to Human Gene Therapy

AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells

(2020) Marcela Garita-Hernandez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astrocyte-selective AAV-ADAMTS4 gene therapy combined with hindlimb rehabilitation promotes functional recovery after spinal cord injury

(2020) Jarred M. Griffin et al.   EXPERIMENTAL NEUROLOGY

AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo

(2020) Sara K. Powell et al.   MOLECULAR THERAPY

Modeling and Rescue of RP2 Retinitis Pigmentosa Using iPSC-Derived Retinal Organoids

(2020) Amelia Lane et al.   Stem Cell Reports

Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain

(2020) Josse A. Depla et al.   Molecular Therapy-Methods & Clinical Development

Crossing the blood-brain barrier with AAV vectors

(2020) Dan Liu et al.   METABOLIC BRAIN DISEASE

Oligodendrogliogenesis and Axon Remyelination after Traumatic Spinal Cord Injuries in Animal Studies: A Systematic Review

(2019) Zahra Hassannejad et al.   NEUROSCIENCE

Neurotropic Properties of AAV-PHP.B Are Shared among Diverse Inbred Strains of Mice

(2019) Yasunori Matsuzaki et al.   MOLECULAR THERAPY

Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors

(2019) Ren-Yuan Bai et al.   GENE THERAPY

Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury

(2019) Jarred M. Griffin et al.   GENE THERAPY

Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina

(2019) Patrizia Tornabene et al.   Science Translational Medicine

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5

(2019) Peter M. Quinn et al.   Stem Cell Reports

A rAAV6 Mutant with Enhanced Targeting for Mouse Retinal Müller Cells

(2019) Jinjing Cao et al.   CURRENT EYE RESEARCH

Charcot–Marie–Tooth disease and related disorders

(2019) Matilde Laurá et al.   CURRENT OPINION IN NEUROLOGY

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

(2019) Josephine Jüttner et al.   NATURE NEUROSCIENCE

Gene Therapy Tools for Brain Diseases

(2019) Selene Ingusci et al.   Frontiers in Pharmacology

Potential of Müller Glia for Retina Neuroprotection

(2019) Karen Eastlake et al.   CURRENT EYE RESEARCH

Myelin status and oligodendrocyte lineage cells over time after spinal cord injury: What do we know and what still needs to be unwrapped?

(2019) Nicole Pukos et al.   GLIA

AAV-PHP.B Administration Results in a Differential Pattern of CNS Biodistribution in Non-human Primates Compared with Mice

(2019) William A. Liguore et al.   MOLECULAR THERAPY

Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges

(2019) Margaret E. Maes et al.   NEUROSCIENCE LETTERS

Enteric neuroplasticity and dysmotility in inflammatory disease: key players and possible therapeutic targets

(2019) Estelle T. Spear et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids

(2019) Qin Huang et al.   PLoS One

The Role of Microglia and Astrocytes in Huntington’s Disease

(2019) Thulani H. Palpagama et al.   Frontiers in Molecular Neuroscience

The Influence of Murine Genetic Background in Adeno-Associated Virus Transduction of the Mouse Brain

(2019) Ting He et al.   Human Gene Therapy Clinical Development

Oligodendrocytes in Development, Myelin Generation and Beyond

(2019) Sarah Kuhn et al.   Cells

Gene therapy approaches targeting Schwann cells for demyelinating neuropathies

(2019) Irene Sargiannidou et al.   BRAIN RESEARCH

Ly6a Differential Expression in Blood–Brain Barrier Is Responsible for Strain Specific Central Nervous System Transduction Profile of AAV-PHP.B

(2019) Ana Rita Batista et al.   HUMAN GENE THERAPY

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism

(2019) Marcus Davidsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The multiple faces of inflammatory enteric glial cells: is Crohn’s disease a gliopathy?

(2018) Camille Pochard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Therapeutic Strategy of Targeting Astrocytes for Neuroprotection in Parkinson's Disease

(2018) Ikuko Miyazaki et al.   CURRENT PHARMACEUTICAL DESIGN

Targeting Enteric Glia in Gastrointestinal Diseases and Motility Disorders: Are We Close?

(2018) Brian D. Gulbransen et al.   GASTROENTEROLOGY

Inflammation in CNS neurodegenerative diseases

(2018) Jodie Stephenson et al.   IMMUNOLOGY

Mapping the Structural Determinants Required for AAVrh.10 Transport across the Blood-Brain Barrier

(2018) Blake H. Albright et al.   MOLECULAR THERAPY

The Neurotropic Properties of AAV-PHP.B Are Limited to C57BL/6J Mice

(2018) Juliette Hordeaux et al.   MOLECULAR THERAPY

Intravenous administration of the adeno-associated virus-PHP.B capsid fails to upregulate transduction efficiency in the marmoset brain

(2018) Yasunori Matsuzaki et al.   NEUROSCIENCE LETTERS

Astrocyte reactivity and astrogliosis after spinal cord injury

(2018) Seiji Okada et al.   NEUROSCIENCE RESEARCH

The multi-dimensional roles of astrocytes in ALS

(2018) Koji Yamanaka et al.   NEUROSCIENCE RESEARCH

Glial Cells Shape Pathology and Repair After Spinal Cord Injury

(2018) Andrew D. Gaudet et al.   Neurotherapeutics

Neurobiological links between depression and AD: The role of TGF-β1 signaling as a new pharmacological target

(2018) Filippo Caraci et al.   PHARMACOLOGICAL RESEARCH

Pharmacology of Recombinant Adeno-associated Virus Production

(2018) Magalie Penaud-Budloo et al.   Molecular Therapy-Methods & Clinical Development

White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

(2018) Sara E. Nasrabady et al.   Acta Neuropathologica Communications

Gene therapy for neurological disorders: progress and prospects

(2018) Benjamin E. Deverman et al.   NATURE REVIEWS DRUG DISCOVERY

Enteric nervous system development: what could possibly go wrong?

(2018) Meenakshi Rao et al.   NATURE REVIEWS NEUROSCIENCE

Efficient Gene Transfer to the Central Nervous System by Single-Stranded Anc80L65

(2018) Eloise Hudry et al.   Molecular Therapy-Methods & Clinical Development

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration

(2018) Suddhasil Mookherjee et al.   Cell Reports

Synthetic AAV/CRISPR vectors for blocking HIV-1 expression in persistently infected astrocytes

(2017) Christine Kunze et al.   GLIA

Microglia in steady state

(2017) Katrin Kierdorf et al.   JOURNAL OF CLINICAL INVESTIGATION

Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno-associated virus delivery in adult rats

(2017) Hongfei Xiang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glioplasticity in irritable bowel syndrome

(2017) N. L. Lilli et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role

(2017) C. J. Garwood et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection

(2017) Sean L. Hammond et al.   PLoS One

The Role of Astrocyte Dysfunction in Parkinson’s Disease Pathogenesis

(2017) Heather D.E. Booth et al.   TRENDS IN NEUROSCIENCES

Müller cells and diabetic retinopathy

(2017) Brandon A. Coughlin et al.   VISION RESEARCH

Selective induction of alternatively spliced FynT isoform by TNF facilitates persistent inflammatory responses in astrocytes

(2017) Chingli Lee et al.   Scientific Reports

A MicroRNA124 Target Sequence Restores Astrocyte Specificity of gfaABC 1 D-Driven Transgene Expression in AAV-Mediated Gene Transfer

(2017) Grit Taschenberger et al.   Molecular Therapy-Nucleic Acids

Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine

(2017) Christopher R. Schlieve et al.   Stem Cell Reports

AAV-Mediated Astrocyte-Specific Gene Expression under Human ALDH1L1 Promoter in Mouse Thalamus

(2017) Wuhyun Koh et al.   Experimental Neurobiology

Fragile X tremor ataxia syndrome and white matter dementia

(2016) Christopher M. Filley   CLINICAL NEUROPSYCHOLOGIST

Glial Cells - The Key Elements of Alzheimers Disease

(2016) David Dzamba et al.   Current Alzheimer Research

Astrocyte roles in traumatic brain injury

(2016) Joshua E. Burda et al.   EXPERIMENTAL NEUROLOGY

Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropism

(2016) S K Powell et al.   GENE THERAPY

Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype

(2016) Andromeda Liñán-Rico et al.   INFLAMMATORY BOWEL DISEASES

Functional Indicators of Glutamate Transport in Single Striatal Astrocytes and the Influence of Kir4.1 in Normal and Huntington Mice

(2016) Anton Dvorzhak et al.   JOURNAL OF NEUROSCIENCE

Enteric glia: the most alimentary of all glia

(2016) Vladimir Grubišić et al.   JOURNAL OF PHYSIOLOGY-LONDON

Systemic application of AAV vectors targeting GFAP-expressing astrocytes in Z -Q175-KI Huntington's disease mice

(2016) Tatyana Vagner et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence

(2016) Sales Ibiza et al.   NATURE

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain

(2016) Benjamin E Deverman et al.   NATURE BIOTECHNOLOGY

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy

(2016) Alexia Kagiava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

White matter injury in ischemic stroke

(2016) Yuan Wang et al.   PROGRESS IN NEUROBIOLOGY

Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo

(2016) Alexandra L. Schober et al.   Frontiers in Cellular Neuroscience

In vivo tissue-tropism of adeno-associated viral vectors

(2016) Arun Srivastava   Current Opinion in Virology

Recombinant Human Myelin-Associated Glycoprotein Promoter Drives Selective AAV-Mediated Transgene Expression in Oligodendrocytes

(2016) Georg von Jonquieres et al.   Frontiers in Molecular Neuroscience

Transcriptional activity of novel ALDH1L1 promoters in the rat brain following AAV vector-mediated gene transfer

(2016) Janitha M Mudannayake et al.   Molecular Therapy-Methods & Clinical Development

Microglia-specific targeting by novel capsid-modified AAV6 vectors

(2016) Awilda M Rosario et al.   Molecular Therapy-Methods & Clinical Development

IntraneuralGJB1gene delivery improves nerve pathology in a model of X-linked Charcot-Marie-Tooth disease

(2015) Irene Sargiannidou et al.   ANNALS OF NEUROLOGY

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

(2015) Lucy Liu et al.   CELL

Adeno-associated virus serotypes for gene therapeutics

(2015) Leszek Lisowski et al.   CURRENT OPINION IN PHARMACOLOGY

Dynamics and Mechanisms of CNS Myelination

(2015) Kathryn K. Bercury et al.   DEVELOPMENTAL CELL

Animal models of Multiple Sclerosis

(2015) Claudio Procaccini et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Gene delivery to rat and human Schwann cells and nerve segments: a comparison of AAV 1–9 and lentiviral vectors

(2015) S A Hoyng et al.   GENE THERAPY

Neuroinflammation in the peripheral nerve: Cause, modulator, or bystander in peripheral neuropathies?

(2015) Rudolf Martini et al.   GLIA

Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models

(2015) Lucie P. Pellissier et al.   HUMAN MOLECULAR GENETICS

An isoform-specific role of FynT tyrosine kinase in Alzheimer's disease

(2015) Chingli Lee et al.   JOURNAL OF NEUROCHEMISTRY

Recombinant adeno-associated viral (rAAV) vectors mediate efficient gene transduction in cultured neonatal and adult microglia

(2015) Wei Su et al.   JOURNAL OF NEUROCHEMISTRY

A New CRB1 Rat Mutation Links Müller Glial Cells to Retinal Telangiectasia

(2015) Min Zhao et al.   JOURNAL OF NEUROSCIENCE

Unique Glycan Signatures Regulate Adeno-Associated Virus Tropism in the Developing Brain

(2015) Giridhar Murlidharan et al.   JOURNAL OF VIROLOGY

Case definition and classification of leukodystrophies and leukoencephalopathies

(2015) Adeline Vanderver et al.   MOLECULAR GENETICS AND METABOLISM

Targeted Gene Delivery to the Enteric Nervous System Using AAV: A Comparison Across Serotypes and Capsid Mutants

(2015) Matthew J Benskey et al.   MOLECULAR THERAPY

GLAST But Not Least—Distribution, Function, Genetics and Epigenetics of l-Glutamate Transport in Brain—Focus on GLAST/EAAT1

(2015) Omar Šerý et al.   NEUROCHEMICAL RESEARCH

Proof-of-concept: neonatal intravenous injection of adeno-associated virus vectors results in successful transduction of myenteric and submucosal neurons in the mouse small and large intestine

(2015) R. Buckinx et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Glial cell regulation of neuronal activity and blood flow in the retina by release of gliotransmitters

(2015) Eric A. Newman   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Astrocyte physiopathology: At the crossroads of intercellular networking, inflammation and cell death

(2015) Daniela Rossi   PROGRESS IN NEUROBIOLOGY

Molecular pathogenesis of retinal and choroidal vascular diseases

(2015) Peter A. Campochiaro   PROGRESS IN RETINAL AND EYE RESEARCH

Neuroinflammation and white matter pathology in schizophrenia: systematic review

(2015) Souhel Najjar et al.   SCHIZOPHRENIA RESEARCH

Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker

(2015) Zhihui Yang et al.   TRENDS IN NEUROSCIENCES

The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease

(2015) Josiane Budni et al.   Aging and Disease

Intracisternal delivery of AAV9 results in oligodendrocyte and motor neuron transduction in the whole central nervous system of cats

(2014) T Bucher et al.   GENE THERAPY

Schwann cells transduced with a lentiviral vector encoding Fgf-2 promote motor neuron regeneration following sciatic nerve injury

(2014) Ilary Allodi et al.   GLIA

Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice

(2014) Egle Cekanaviciute et al.   GLIA

White matter injury: Ischemic and nonischemic

(2014) Robert F. Fern et al.   GLIA

Transgenic replacement of Cx32 in gap junction-deficient oligodendrocytes rescues the phenotype of a hypomyelinating leukodystrophy model

(2014) Natasa Schiza et al.   HUMAN MOLECULAR GENETICS

Gene delivery targeted to oligodendrocytes using a lentiviral vector

(2014) Alexia Kagiava et al.   JOURNAL OF GENE MEDICINE

White matter lesions and depression: A systematic review and meta-analysis

(2014) Li Wang et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Global CNS Transduction of Adult Mice by Intravenously Delivered rAAVrh.8 and rAAVrh.10 and Nonhuman Primates by rAAVrh.10

(2014) Bin Yang et al.   MOLECULAR THERAPY

Endothelin-1 is over-expressed in amyotrophic lateral sclerosis and induces motor neuron cell death

(2014) Eugenia Ranno et al.   NEUROBIOLOGY OF DISEASE

Drawing a high-resolution functional map of adeno-associated virus capsid by massively parallel sequencing

(2014) Kei Adachi et al.   Nature Communications

Biodistribution of adeno-associated virus serotype 9 (AAV9) vector after intrathecal and intravenous delivery in mouse

(2014) Daniel J. Schuster et al.   Frontiers in Neuroanatomy

Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice

(2014) Sara E. Gombash et al.   Frontiers in Molecular Neuroscience

AAV-Mediated Gene Therapy for Research and Therapeutic Purposes

(2014) R. Jude Samulski et al.   Annual Review of Virology

Suppression of leaky expression of adenovirus genes by insertion of microRNA-targeted sequences in the replication-incompetent adenovirus vector genome

(2014) Kahori Shimizu et al.   Molecular Therapy-Methods & Clinical Development

Specific tools for targeting and expression in Müller glial cells

(2014) Lucie P Pellissier et al.   Molecular Therapy-Methods & Clinical Development

Ca2+ Responses in Enteric Glia Are Mediated by Connexin-43 Hemichannels and Modulate Colonic Transit in Mice

(2013) Jonathon L. McClain et al.   GASTROENTEROLOGY

New functions of Müller cells

(2013) Andreas Reichenbach et al.   GLIA

Intracerebroventricular Injection of Adeno-Associated Virus 6 and 9 Vectors for Cell Type–Specific Transgene Expression in the Spinal Cord

(2013) Elisabeth Dirren et al.   HUMAN GENE THERAPY

Rationally designed capsid and transgene cassette of AAV6 vectors for dendritic cell-based cancer immunotherapy

(2013) Jheel Pandya et al.   IMMUNOLOGY AND CELL BIOLOGY

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Glia and pain: Is chronic pain a gliopathy?

(2013) Ru-Rong Ji et al.   PAIN

Glial Promoter Selectivity following AAV-Delivery to the Immature Brain

(2013) Georg von Jonquieres et al.   PLoS One

Lentiviral Vector-Mediated Gradients of GDNF in the Injured Peripheral Nerve: Effects on Nerve Coil Formation, Schwann Cell Maturation and Myelination

(2013) Ruben Eggers et al.   PLoS One

Fractalkine mediates inflammatory pain through activation of satellite glial cells

(2013) G. R. Souza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered astrocytic response to activation in SOD1G93Amice and its implications on amyotrophic lateral sclerosis pathogenesis

(2012) Chen Benkler et al.   GLIA

Correction of Brain Oligodendrocytes by AAVrh.10 Intracerebral Gene Therapy in Metachromatic Leukodystrophy Mice

(2012) Françoise Piguet et al.   HUMAN GENE THERAPY

Glycated AAV Vectors: Chemical Redirection of Viral Tissue Tropism

(2011) Eric D. Horowitz et al.   BIOCONJUGATE CHEMISTRY

Adenosine kinase as a target for therapeutic antisense strategies in epilepsy

(2011) Panos Theofilas et al.   EPILEPSIA

The CC genotype of transforming growth factor-β1 increases the risk of late-onset Alzheimer's disease and is associated with AD-related depression

(2011) Filippo Caraci et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

(2011) T H Hutson et al.   GENE THERAPY

Schwann cell targeting via intrasciatic injection of AAV8 as gene therapy strategy for peripheral nerve regeneration

(2011) J Homs et al.   GENE THERAPY

Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*

(2011) Leonid Tarassishin et al.   GLIA

Preclinical Differences of Intravascular AAV9 Delivery to Neurons and Glia: A Comparative Study of Adult Mice and Nonhuman Primates

(2011) Steven J Gray et al.   MOLECULAR THERAPY

AAV Mediated GDNF Secretion From Retinal Glia Slows Down Retinal Degeneration in a Rat Model of Retinitis Pigmentosa

(2011) Deniz Dalkara et al.   MOLECULAR THERAPY

Several rAAV Vectors Efficiently Cross the Blood–brain Barrier and Transduce Neurons and Astrocytes in the Neonatal Mouse Central Nervous System

(2011) Hongwei Zhang et al.   MOLECULAR THERAPY

White matter lesions in Parkinson disease

(2011) Nicolaas I. Bohnen et al.   Nature Reviews Neurology

TNFα Controls Glutamatergic Gliotransmission in the Hippocampal Dentate Gyrus

(2011) Mirko Santello et al.   NEURON

DJ-1 knock-down impairs astrocyte mitochondrial function

(2011) N.J. Larsen et al.   NEUROSCIENCE

Satellite glial cells in sympathetic and parasympathetic ganglia: In search of function

(2010) Menachem Hanani   BRAIN RESEARCH REVIEWS

Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease

(2010) James B Koprich et al.   Molecular Neurodegeneration

Can satellite glial cells be therapeutic targets for pain control?

(2010) Luc Jasmin et al.   Neuron Glia Biology

Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction

(2010) Y. Xie et al.   NEUROSCIENCE

Glial Cells and Chronic Pain

(2010) Romain-Daniel Gosselin et al.   NEUROSCIENTIST

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress

(2009) Michael I. Dorrell et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficient Gene Delivery and Selective Transduction of Glial Cells in the Mammalian Brain by AAV Serotypes Isolated From Nonhuman Primates

(2009) Patricia A Lawlor et al.   MOLECULAR THERAPY

Molecular Evolution of Adeno-associated Virus for Enhanced Glial Gene Delivery

(2009) James T Koerber et al.   MOLECULAR THERAPY

Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood–Brain Barrier (BBB)

(2009) Steven J Gray et al.   MOLECULAR THERAPY

Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy

(2009) Yong Hong Chen et al.   NATURE MEDICINE

Gliopathic Pain: When Satellite Glial Cells Go Bad

(2009) Peter T. Ohara et al.   NEUROSCIENTIST

A Novel Adeno-Associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells

(2009) Ryan R. Klimczak et al.   PLoS One

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

(2008) M Hellström et al.   GENE THERAPY

GFAPpromoter elements required for region-specific and astrocyte-specific expression

(2008) Youngjin Lee et al.   GLIA

Engineered lentiviral vector targeting astrocytesIn vivo

(2008) Angélique Colin et al.   GLIA

Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera

(2008) Robert C. Carlisle et al.   JOURNAL OF GENE MEDICINE

Novel AAV serotypes for improved ocular gene transfer

(2008) Corinna Lebherz et al.   JOURNAL OF GENE MEDICINE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Expanded Repertoire of AAV Vector Serotypes Mediate Unique Patterns of Transduction in Mouse Brain

(2008) Cassia N Cearley et al.   MOLECULAR THERAPY

High-efficiency Transduction of the Mouse Retina by Tyrosine-mutant AAV Serotype Vectors

(2008) Hilda Petrs-Silva et al.   MOLECULAR THERAPY

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

(2008) Kevin D Foust et al.   NATURE BIOTECHNOLOGY

Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

(2008) L. Zhong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific AAV serotypes stably transduce primary hippocampal and cortical cultures with high efficiency and low toxicity

(2007) Nicolas C. Royo et al.   BRAIN RESEARCH

AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method

(2007) Ronald L Klein et al.   MOLECULAR THERAPY

Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro

(2007) Douglas B. Howard et al.   VIROLOGY