Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy

A large animal model of spinal muscular atrophy and correction of phenotype

(2015) Sandra I. Duque et al.   ANNALS OF NEUROLOGY

IntraneuralGJB1gene delivery improves nerve pathology in a model of X-linked Charcot-Marie-Tooth disease

(2015) Irene Sargiannidou et al.   ANNALS OF NEUROLOGY

Measurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR

(2015) I Christodoulou et al.   GENE THERAPY

Charcot-Marie-Tooth disease and pathways to molecular based therapies

(2014) T. Harel et al.   CLINICAL GENETICS

Recent advances in Charcot–Marie–Tooth disease

(2014) Jonathan Baets et al.   CURRENT OPINION IN NEUROLOGY

Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy

(2014) A. Lattanzi et al.   HUMAN MOLECULAR GENETICS

Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain

(2014) Ellen C Dengler et al.   Journal of Neuroinflammation

In vivo introduction of transgenes into mouse sciatic nerve cells in situ using viral vectors

(2014) Sergio Gonzalez et al.   Nature Protocols

Animal models and therapeutic prospects for Charcot-Marie-Tooth disease

(2013) Delphine Bouhy et al.   ANNALS OF NEUROLOGY

Inherited Peripheral Neuropathies

(2013) Mario A. Saporta et al.   NEUROLOGIC CLINICS

Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy

(2013) A. Biffi et al.   SCIENCE

AAV8gfp preferentially targets large diameter dorsal root ganglion neurones after both intra-dorsal root ganglion and intrathecal injection

(2012) Steven J. Jacques et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection

(2011) A. Biffi et al.   BLOOD

Schwann cell targeting via intrasciatic injection of AAV8 as gene therapy strategy for peripheral nerve regeneration

(2011) J Homs et al.   GENE THERAPY

The Role of Gap Junctions in Charcot-Marie-Tooth Disease

(2011) K. A. Kleopa   JOURNAL OF NEUROSCIENCE

Systemic Gene Delivery in Large Species for Targeting Spinal Cord, Brain, and Peripheral Tissues for Pediatric Disorders

(2011) Adam K Bevan et al.   MOLECULAR THERAPY

Homeostatic regulation of the endoneurial microenvironment during development, aging and in response to trauma, disease and toxic insult

(2010) Andrew P. Mizisin et al.   ACTA NEUROPATHOLOGICA

Attenuation of MCP-1/CCL2 expression ameliorates neuropathy in a mouse model for Charcot–Marie–Tooth 1X

(2010) Janos Groh et al.   HUMAN MOLECULAR GENETICS

Gene knockdown with lentiviral vector-mediated intrathecal RNA interference of protein kinase C gamma reverses chronic morphine tolerance in rats

(2010) Zongbin Song et al.   JOURNAL OF GENE MEDICINE

Axonal Pathology Precedes Demyelination in a Mouse Model of X-Linked Demyelinating/Type I Charcot-Marie Tooth Neuropathy

(2010) Natalie Vavlitou et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Polyethylene Glycol Rapidly Restores Axonal Integrity and Improves the Rate of Motor Behavior Recovery After Sciatic Nerve Crush Injury

(2010) Joshua M. Britt et al.   JOURNAL OF NEUROPHYSIOLOGY

The Expression of TAG-1 in Glial Cells Is Sufficient for the Formation of the Juxtaparanodal Complex and the Phenotypic Rescue of Tag-1 Homozygous Mutants in the CNS

(2010) M. Savvaki et al.   JOURNAL OF NEUROSCIENCE

Differential Adeno-Associated Virus Mediated Gene Transfer to Sensory Neurons following Intrathecal Delivery by Direct Lumbar Puncture

(2010) Lucy Vulchanova et al.   Molecular Pain

Connexin32 Mutations Cause Loss of Function in Schwann Cells and Oligodendrocytes Leading to PNS and CNS Myelination Defects

(2009) I. Sargiannidou et al.   JOURNAL OF NEUROSCIENCE

Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct

(2007) Meejin Ahn et al.   JOURNAL OF NEUROSCIENCE RESEARCH