Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury

Improved gene delivery to adult mouse spinal cord through the use of engineered hybrid adeno-associated viral serotypes

(2017) J J Siu et al.   GENE THERAPY

Widespread and Efficient Transduction of Spinal Cord and Brain Following Neonatal AAV Injection and Potential Disease Modifying Effect in ALS Mice

(2015) Jacob I Ayers et al.   MOLECULAR THERAPY

Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy

(2014) D Young et al.   GENE THERAPY

Transduction efficiency of neurons and glial cells by AAV-1, -5, -9, -rh10 and -hu11 serotypes in rat spinal cord following contusion injury

(2014) H A Petrosyan et al.   GENE THERAPY

A method to investigate radial glia cell behavior using two-photon time-lapse microscopy in an ex vivo model of spinal cord development

(2014) Janelle M. P. Pakan et al.   Frontiers in Neuroanatomy

Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury

(2013) Simon J. O’Carroll et al.   NEUROSCIENCE RESEARCH

Assessment of Tropism and Effectiveness of New Primate-Derived Hybrid Recombinant AAV Serotypes in the Mouse and Primate Retina

(2013) Peter Charbel Issa et al.   PLoS One

Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors

(2013) Nicolas Merienne et al.   Frontiers in Cellular Neuroscience

Improved adeno-associated virus (AAV) serotype 1 and 5 vectors for gene therapy

(2013) Dwaipayan Sen et al.   Scientific Reports

Intraspinal AAV Injections Immediately Rostral to a Thoracic Spinal Cord Injury Site Efficiently Transduces Neurons in Spinal Cord and Brain

(2013) Michelle C Klaw et al.   Molecular Therapy-Nucleic Acids

Phenotypic Changes, Signaling Pathway, and Functional Correlates of GPR17-expressing Neural Precursor Cells during Oligodendrocyte Differentiation

(2011) Marta Fumagalli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient Gene Therapy for Parkinson's Disease Using Astrocytes as Hosts for Localized Neurotrophic Factor Delivery

(2011) Anja Drinkut et al.   MOLECULAR THERAPY

Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

(2010) Pavel I Ortinski et al.   NATURE NEUROSCIENCE

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

(2009) Frederico A.C. Azevedo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Effect of Genome Size on AAV Vector Packaging

(2009) Zhijian Wu et al.   MOLECULAR THERAPY

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS

GFAPpromoter elements required for region-specific and astrocyte-specific expression

(2008) Youngjin Lee et al.   GLIA

AAV Vector–mediated RNAi of Mutant Huntingtin Expression Is Neuroprotective in a Novel Genetic Rat Model of Huntington's Disease

(2008) Nicholas R Franich et al.   MOLECULAR THERAPY

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

(2008) Kevin D Foust et al.   NATURE BIOTECHNOLOGY

Specification of CNS glia from neural stem cells in the embryonic neuroepithelium

(2007) N. Kessaris et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES