AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells

Comparative AAV-eGFP Transgene Expression Using Vector Serotypes 1–9, 7m8, and 8b in Human Pluripotent Stem Cells, RPEs, and Human and Rat Cortical Neurons

(2019) Thu T. Duong et al.   Stem Cells International

Restoration of visual function by transplantation of optogenetically engineered photoreceptors

(2019) Marcela Garita-Hernandez et al.   Nature Communications

Assessment of AAV Vector Tropisms for Mouse and Human Pluripotent Stem Cell–Derived RPE and Photoreceptor Cells

(2018) Anai Gonzalez-Cordero et al.   HUMAN GENE THERAPY

An Alternate Route for Adeno-associated Virus (AAV) Entry Independent of AAV Receptor

(2018) Amanda M. Dudek et al.   JOURNAL OF VIROLOGY

Optogenetic Light Sensors in Human Retinal Organoids

(2018) Marcela Garita-Hernandez et al.   Frontiers in Neuroscience

Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection

(2017) Lolita Petit et al.   HUMAN GENE THERAPY

Human ESC–derived retinal epithelial cell sheets potentiate rescue of photoreceptor cell loss in rats with retinal degeneration

(2017) Karim Ben M’Barek et al.   Science Translational Medicine

Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions

(2017) Sacha Reichman et al.   STEM CELLS

Isolation and Comparative Transcriptome Analysis of Human Fetal and iPSC-Derived Cone Photoreceptor Cells

(2017) Emily Welby et al.   Stem Cell Reports

Vectors and Gene Delivery to the Retina

(2017) Arthur Planul et al.   Annual Review of Vision Science

Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant -7m8

(2016) Hanen Khabou et al.   BIOTECHNOLOGY AND BIOENGINEERING

Cone-Specific Promoters for Gene Therapy of Achromatopsia and Other Retinal Diseases

(2016) Guo-Jie Ye et al.   HUMAN GENE THERAPY

An essential receptor for adeno-associated virus infection

(2016) S. Pillay et al.   NATURE

Adeno-Associated Virus at 50: A Golden Anniversary of Discovery, Research, and Gene Therapy Success—A Personal Perspective

(2015) Eric Hastie et al.   HUMAN GENE THERAPY

Correction: AAV9 Targets Cone Photoreceptors in the Nonhuman Primate Retina

(2014) Luk H. Vandenberghe et al.   PLoS One

From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium

(2014) S. Reichman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vector platforms for gene therapy of inherited retinopathies

(2014) Ivana Trapani et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs

(2014) Xiufeng Zhong et al.   Nature Communications

Tropisms of AAV for Subretinal Delivery to the Neonatal Mouse Retina and Its Application for In Vivo Rescue of Developmental Photoreceptor Disorders

(2013) Satoshi Watanabe et al.   PLoS One

In Vivo-Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

(2013) D. Dalkara et al.   Science Translational Medicine

Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve

(2013) V Pernet et al.   Cell Death & Disease

Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

(2012) Tokushige Nakano et al.   Cell Stem Cell

Dosage Thresholds for AAV2 and AAV8 Photoreceptor Gene Therapy in Monkey

(2011) L. H. Vandenberghe et al.   Science Translational Medicine

A Conserved Role for Syndecan Family Members in the Regulation of Whole-Body Energy Metabolism

(2010) Maria De Luca et al.   PLoS One

Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat

(2009) Amanda-Jayne Carr et al.   PLoS One

Modeling early retinal development with human embryonic and induced pluripotent stem cells

(2009) J. S. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elucidating the phenomenon of HESC-derived RPE: Anatomy of cell genesis, expansion and retinal transplantation

(2008) Anthony Vugler et al.   EXPERIMENTAL NEUROLOGY