The Beneficial Effects of Saffron Extract on Potential Oxidative Stress in Cardiovascular Diseases
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Title
The Beneficial Effects of Saffron Extract on Potential Oxidative Stress in Cardiovascular Diseases
Authors
Keywords
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Journal
Oxidative Medicine and Cellular Longevity
Volume 2021, Issue -, Pages 1-14
Publisher
Hindawi Limited
Online
2021-01-21
DOI
10.1155/2021/6699821
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Note: Only part of the references are listed.- Safranal, an active constituent of saffron, ameliorates myocardial ischemia via reduction of oxidative stress and regulation of Ca2+ homeostasis
- (2020) Yurun Xue et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- The Role of Antioxidants in Ameliorating Cyclophosphamide-Induced Cardiotoxicity
- (2020) Muluken Altaye Ayza et al. Oxidative Medicine and Cellular Longevity
- Mitochondrial ROS in myocardial ischemia reperfusion and remodeling
- (2020) Heiko Bugger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro
- (2020) Xi Chu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The Crocus sativus Compounds trans-Crocin 4 and trans-Crocetin Modulate the Amyloidogenic Pathway and Tau Misprocessing in Alzheimer Disease Neuronal Cell Culture Models
- (2019) Ioanna Chalatsa et al. Frontiers in Neuroscience
- Crocin inhibits the migration, invasion, and epithelial-mesenchymal transition of gastric cancer cells via miR-320/KLF5/HIF-1α signaling
- (2019) Ying Zhou et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Reactive Oxygen Species (ROS)-Based Nanomedicine
- (2019) Bowen Yang et al. CHEMICAL REVIEWS
- Effect of Different Drying Methods on the Physicochemical Properties and Bioactive Components of Saffron Powder
- (2019) Zahra Aghaei et al. PLANT FOODS FOR HUMAN NUTRITION
- New opportunities for targeting redox dysregulation in cardiovascular disease
- (2019) Kristen J Bubb et al. CARDIOVASCULAR RESEARCH
- Insights into Doxorubicin-induced Cardiotoxicity: Molecular Mechanisms, Preventive Strategies, and Early Monitoring
- (2019) Nadine Wenningmann et al. MOLECULAR PHARMACOLOGY
- Targeting Early Atherosclerosis: A Focus on Oxidative Stress and Inflammation
- (2019) Patricia Marchio et al. Oxidative Medicine and Cellular Longevity
- Crocin Protects Cardiomyocytes against LPS-Induced Inflammation
- (2019) Vafa Baradaran Rahimi et al. Pharmacological Reports
- Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis
- (2019) Weiyue Jin et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Hypoxia-Inducible Factors as an Alternative Source of Treatment Strategy for Cancer
- (2019) Musbau Adewumi Akanji et al. Oxidative Medicine and Cellular Longevity
- Polyphenols in human nutrition: from the in vitro antioxidant capacity to the beneficial effects on cardiometabolic health and related inter-individual variability – an overview and perspective
- (2019) T. Ruskovska et al. BRITISH JOURNAL OF NUTRITION
- A comparative study of the role of crocin and sitagliptin in attenuation of STZ-induced diabetes mellitus and the associated inflammatory and apoptotic changes in pancreatic β-islets
- (2019) Mahmoud M. Samaha et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Regulated preparation of Crocin-1 or Crocin-2′ Triggered by the Cosolvent DMSO Using Bs-GT/At-SuSy One-Pot Reaction
- (2019) Feng Liu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets
- (2019) Yixuan Zhang et al. Nature Reviews Cardiology
- Effects of crocin and saffron aqueous extract on gene expression of SIRT1 , AMPK , LOX1 , NF‐κB , and MCP‐1 in patients with coronary artery disease: A randomized placebo‐controlled clinical trial
- (2019) Nasim Abedimanesh et al. PHYTOTHERAPY RESEARCH
- The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy
- (2018) I. Marques-Aleixo et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Cardiotoxic effects of chemotherapy: A review of both cytotoxic and molecular targeted oncology therapies and their effect on the cardiovascular system
- (2018) Hani M Babiker et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications
- (2018) Péter Ferdinandy et al. EUROPEAN HEART JOURNAL
- ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection
- (2018) Susana Cadenas FREE RADICAL BIOLOGY AND MEDICINE
- Saffron in the treatment of depression, anxiety and other mental disorders: Current evidence and potential mechanisms of action
- (2018) Mojtaba Shafiee et al. JOURNAL OF AFFECTIVE DISORDERS
- Trimetazidine protects against myocardial ischemia/reperfusion injury by inhibiting excessive autophagy
- (2018) Shiyong Wu et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity
- (2018) Mônica Samuel Avila et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Anticancer drug-induced cardiac rhythm disorders: Current knowledge and basic underlying mechanisms
- (2018) Joachim Alexandre et al. PHARMACOLOGY & THERAPEUTICS
- PPARγ agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation
- (2018) Ekaterina Legchenko et al. Science Translational Medicine
- Rapid determination of crocins in saffron by near-infrared spectroscopy combined with chemometric techniques
- (2018) Shuailing Li et al. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
- Assessment of Left Ventricular Function by Echocardiography
- (2018) Elizabeth Potter et al. JACC-Cardiovascular Imaging
- 3D bioprinting for cardiovascular regeneration and pharmacology
- (2018) Haitao Cui et al. ADVANCED DRUG DELIVERY REVIEWS
- Cardiovascular disease models: A game changing paradigm in drug discovery and screening
- (2018) Houman Savoji et al. BIOMATERIALS
- Saffron; An updated review on biological properties with special focus on cardiovascular effects
- (2018) Samad Ghaffari et al. BIOMEDICINE & PHARMACOTHERAPY
- Geographical identification of saffron (Crocus sativus L.) by linear discriminant analysis applied to the UV–visible spectra of aqueous extracts
- (2017) Angelo Antonio D’Archivio et al. FOOD CHEMISTRY
- Comparative evaluation of an ISO 3632 method and an HPLC-DAD method for safranal quantity determination in saffron
- (2017) M. Valle García-Rodríguez et al. FOOD CHEMISTRY
- Crocin modulates IL-4/IL-13 signaling and ameliorates experimentally induced allergic airway asthma in a murine model
- (2017) Haidy Yosri et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis
- (2017) Andrey Lozhkin et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Effects of saffron and its constituents, crocin-1, crocin-2, and crocetin on α-synuclein fibrils
- (2017) Eiji Inoue et al. Journal of Natural Medicines
- Basic Biology of Oxidative Stress and the Cardiovascular System
- (2017) Michael N. Sack et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Cardiotoxic effects of anthracycline-based therapy: what is the evidence and what are the potential harms?
- (2017) Bennett E Levis et al. LANCET ONCOLOGY
- Saffron ( Crocus sativus ) intake provides nutritional preconditioning against myocardial ischemia–reperfusion injury in Wild Type and ApoE (−/−) mice: Involvement of Nrf2 activation
- (2017) P. Efentakis et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Cardiovascular Bio-Engineering: Current State of the Art
- (2017) Teresa Simon-Yarza et al. Journal of Cardiovascular Translational Research
- Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies
- (2017) Xinyu Yang et al. Frontiers in Physiology
- Crocin protects against doxorubicin-induced myocardial toxicity in rats through down-regulation of inflammatory and apoptic pathways
- (2016) Nehal M. Elsherbiny et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Crocetin ester improves myocardial ischemia via Rho/ROCK/NF-κB pathway
- (2016) Zhiheng Huang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Pathophysiology of cardiotoxicity induced by nonanthracycline chemotherapy
- (2016) Clelia Madeddu et al. Journal of Cardiovascular Medicine
- Crocin treatment prevents doxorubicin-induced cardiotoxicity in rats
- (2016) Nasser Razmaraii et al. LIFE SCIENCES
- Constituents of Saffron (Crocus sativus L.) as Potential Candidates for the Treatment of Anxiety Disorders and Schizophrenia
- (2016) Nikolaos Pitsikas MOLECULES
- Drug-induced mitochondrial dysfunction and cardiotoxicity
- (2015) Zoltán V Varga et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Saffron extracts alleviate cardiomyocytes injury induced by doxorubicin and ischemia-reperfusionin vitro
- (2015) Nathalie Chahine et al. DRUG AND CHEMICAL TOXICOLOGY
- Crocin and quercetin prevent PAT-induced apoptosis in mammalian cells: Involvement of ROS-mediated ER stress pathway
- (2015) Manel Boussabbeh et al. ENVIRONMENTAL TOXICOLOGY
- Zearalenone-induced changes in biochemical parameters, oxidative stress and apoptosis in cardiac tissue
- (2015) I Ben Salem et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- HIF-1 at the crossroads of hypoxia, inflammation, and cancer
- (2015) Kuppusamy Balamurugan INTERNATIONAL JOURNAL OF CANCER
- Crocin Prevents Patulin-Induced Acute Toxicity in Cardiac Tissues via the Regulation of Oxidative Damage and Apoptosis
- (2015) Manel Boussabbeh et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Structural characterization of highly glucosylated crocins and regulation of their biosynthesis during flower development in Crocus
- (2015) Oussama Ahrazem et al. Frontiers in Plant Science
- Oxidative Stress and Early Atherosclerosis: Novel Antioxidant Treatment
- (2014) Dimitris Tousoulis et al. CARDIOVASCULAR DRUGS AND THERAPY
- Protective effects of crocetin pretreatment on myocardial injury in an ischemia/reperfusion rat model
- (2014) Yanyan Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Flavonoid Determination in the Quality Control of Floral Bioresidues from Crocus sativus L.
- (2014) Jéssica Serrano-Díaz et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Evaluation of antioxidant activities of bioactive compounds and various extracts obtained from saffron (Crocus sativus L.): a review
- (2014) Somayeh Rahaiee et al. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
- Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron
- (2014) Tomáš Šimůnek et al. Pharmacological Reports
- Modulating Effects of Pycnogenol® on Oxidative Stress and DNA Damage Induced by Sepsis in Rats
- (2014) Gökçe Taner et al. PHYTOTHERAPY RESEARCH
- Protective Effects of Crocin on Hemodynamic Parameters and Infarct Size in Comparison with Vitamin E after Ischemia Reperfusion in Isolated Rat Hearts
- (2014) Mahin Dianat et al. PLANTA MEDICA
- Cardioprotective Effect of Saffron Extracts against Acute Doxorubicin Toxicity in Isolated Rabbit Hearts Submitted to Ischemia-Reperfusion Injury
- (2014) Nathalie Chahine et al. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
- ATP stimulates PGE2/cyclin D1-dependent VSMCs proliferation via STAT3 activation: Role of PKCs-dependent NADPH oxidase/ROS generation
- (2013) I-Ta Lee et al. BIOCHEMICAL PHARMACOLOGY
- Protective effect of crocin on diazinon induced cardiotoxicity in rats in subchronic exposure
- (2013) Bibi Marjan Razavi et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Bioactivity assessment and toxicity of crocin: A comprehensive review
- (2013) Seyedeh Hoda Alavizadeh et al. FOOD AND CHEMICAL TOXICOLOGY
- Determination of volatile components of saffron by optimised ultrasound-assisted extraction in tandem with dispersive liquid–liquid microextraction followed by gas chromatography–mass spectrometry
- (2013) Hassan Sereshti et al. FOOD CHEMISTRY
- Cyclophosphamide-induced Cardiotoxicity with a Prolonged Clinical Course Diagnosed on an Endomyocardial Biopsy
- (2013) Saburo Kusumoto et al. INTERNAL MEDICINE
- Proanthocyanidin prevents myocardial ischemic injury in adult rats
- (2013) Adem Guler et al. MEDICAL SCIENCE MONITOR
- Protective effect of saffron extract against doxorubicin cardiotoxicity in isolated rabbit heart
- (2013) Nathalie Chahine et al. PHARMACEUTICAL BIOLOGY
- Crocin “saffron” protects against beryllium chloride toxicity in rats through diminution of oxidative stress and enhancing gene expression of antioxidant enzymes
- (2012) Hesham A. El-Beshbishy et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Cancer drugs and the heart: importance and management
- (2012) T. M. Suter et al. EUROPEAN HEART JOURNAL
- Mitochondria in cardiac hypertrophy and heart failure
- (2012) Mariana G. Rosca et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Akt/GSK-3β/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia–reperfusion injury in rats
- (2011) Saurabh Bharti et al. EUROPEAN JOURNAL OF NUTRITION
- Signal transduction by reactive oxygen species
- (2011) Toren Finkel JOURNAL OF CELL BIOLOGY
- Development of novel inhibitors targeting HIF-1α towards anticancer drug discovery
- (2010) Nilambari Yewalkar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The Effect of Saffron Consumption on Biochemical and Histopathological Heart Indices of Rats with Myocardial Infarction
- (2010) Siyavash Joukar et al. Cardiovascular Toxicology
- Evaluation of the safety and antioxidant activities of Crocus sativus and Propolis ethanolic extracts
- (2010) A. Ramadan et al. Journal of Saudi Chemical Society
- Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats
- (2009) S.N. Goyal et al. PHYTOMEDICINE
- EFFECT OF CROCETIN ON BLOOD PRESSURE RESTORATION AND SYNTHESIS OF INFLAMMATORY MEDIATORS IN HEART AFTER HEMORRHAGIC SHOCK IN ANESTHETIZED RATS
- (2009) Junling Yan et al. SHOCK
- Oxidative stress parameters in patients with slow coronary flow
- (2008) Yasar Enli et al. ADVANCES IN THERAPY
- Redox Regulation of Cell Survival
- (2008) Dunyaporn Trachootham et al. ANTIOXIDANTS & REDOX SIGNALING
- Relationship between oxidative stress and HIF-1α mRNA during sustained hypoxia in humans
- (2008) Vincent Pialoux et al. FREE RADICAL BIOLOGY AND MEDICINE
- Effect of short-term exposure to zidovudine (AZT) on the expression of mitochondria-related genes in skeletal muscle of neonatal mice
- (2008) Varsha G. Desai et al. MITOCHONDRION
- Saffron, an alternative crop for sustainable agricultural systems. A review
- (2007) F. Gresta et al. Agronomy for Sustainable Development
- Dose translation from animal to human studies revisited
- (2007) Shannon Reagan-Shaw et al. FASEB JOURNAL
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