New opportunities for targeting redox dysregulation in cardiovascular disease
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Title
New opportunities for targeting redox dysregulation in cardiovascular disease
Authors
Keywords
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Journal
CARDIOVASCULAR RESEARCH
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2019-07-10
DOI
10.1093/cvr/cvz183
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Note: Only part of the references are listed.- Unlockable Nanocomplexes with Self-Accelerating Nucleic Acid Release for Effective Staged Gene Therapy of Cardiovascular Diseases
- (2018) Jing-Jun Nie et al. ADVANCED MATERIALS
- Vascular smooth muscle contraction in hypertension
- (2018) Rhian M Touyz et al. CARDIOVASCULAR RESEARCH
- Reactive Oxygen Species in Metabolic and Inflammatory Signaling
- (2018) Steven J. Forrester et al. CIRCULATION RESEARCH
- Redox Regulation Beyond ROS
- (2018) Ralf P. Brandes et al. CIRCULATION RESEARCH
- Strategies for the enhanced intracellular delivery of nanomaterials
- (2018) Cláudia Azevedo et al. DRUG DISCOVERY TODAY
- VEGFR (Vascular Endothelial Growth Factor Receptor) Inhibition Induces Cardiovascular Damage via Redox-Sensitive ProcessesNovelty and Significance
- (2018) Karla B. Neves et al. HYPERTENSION
- Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older AdultsNovelty and Significance
- (2018) Matthew J. Rossman et al. HYPERTENSION
- Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
- (2018) Antonio Cuadrado et al. PHARMACOLOGICAL REVIEWS
- MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation
- (2018) Catherine A. Makarewich et al. Cell Reports
- The role of mitochondrial cardiolipin in heart function and its implication in cardiac disease
- (2018) Jan Dudek et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models
- (2018) Masaki Tokutome et al. CARDIOVASCULAR RESEARCH
- A Small Peptide Ac-SDKP Inhibits Radiation-Induced Cardiomyopathy
- (2018) Umesh C. Sharma et al. Circulation-Heart Failure
- Current perspectives in fragment-based lead discovery (FBLD)
- (2017) Bas Lamoree et al. Essays in Biochemistry
- Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up
- (2017) Juha Hartikainen et al. EUROPEAN HEART JOURNAL
- Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
- (2017) Tore Skotland et al. EUROPEAN JOURNAL OF CANCER
- The NRF2 activator DH404 attenuates adverse ventricular remodeling post-myocardial infarction by modifying redox signalling
- (2017) Kristen J. Bubb et al. FREE RADICAL BIOLOGY AND MEDICINE
- Redox modification of caveolar proteins in the cardiovascular system- role in cellular signalling and disease
- (2017) Kristen J. Bubb et al. FREE RADICAL BIOLOGY AND MEDICINE
- Placental Vesicles Carry Active Endothelial Nitric Oxide Synthase and Their Activity is Reduced in PreeclampsiaNovelty and Significance
- (2017) Carolina Motta-Mejia et al. HYPERTENSION
- Nanoparticle-mediated drug delivery system for atherosclerotic cardiovascular disease
- (2017) Tetsuya Matoba et al. Journal of Cardiology
- Amelioration of atherosclerotic inflammation and plaques via endothelial adrenoceptor-targeted eNOS gene delivery using redox-sensitive polymer bearing l -arginine
- (2017) Qurrat Ul Ain et al. JOURNAL OF CONTROLLED RELEASE
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Redox Regulation of Inflammatory Processes Is Enzymatically Controlled
- (2017) Inken Lorenzen et al. Oxidative Medicine and Cellular Longevity
- Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet
- (2017) Meng Zhang et al. PLoS One
- Mining for Micropeptides
- (2017) Catherine A. Makarewich et al. TRENDS IN CELL BIOLOGY
- NOX Activation by Subunit Interaction and Underlying Mechanisms in Disease
- (2017) Radhika Rastogi et al. Frontiers in Cellular Neuroscience
- Caveolin-1 scaffolding domain peptides enhance anti-inflammatory effect of heme oxygenase-1 through interrupting its interact with caveolin-1
- (2017) Ping Weng et al. Oncotarget
- Redox Regulation and Noncoding RNAs
- (2017) Matthias S. Leisegang et al. ANTIOXIDANTS & REDOX SIGNALING
- P66Shc-Induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1Highlights
- (2016) Qiuxia Li et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Therapeutic potential of NADPH oxidase 1/4 inhibitors
- (2016) G Teixeira et al. BRITISH JOURNAL OF PHARMACOLOGY
- Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System
- (2016) Kathy K. Griendling et al. CIRCULATION RESEARCH
- RNA Therapeutics for Treatment of Cardiovascular Diseases
- (2016) Tina Lucas et al. CIRCULATION RESEARCH
- Gene therapy for the treatment of heart failure: promise postponed
- (2016) Jean-Sebastien Hulot et al. EUROPEAN HEART JOURNAL
- Redox signaling in the cardiomyocyte: From physiology to failure
- (2016) Celio X.C. Santos et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- EFFECTS OF A NOVEL TETRAPEPTIDE IN HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF): A PHASE I RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF ELAMIPRETIDE
- (2016) Melissa A. Daubert et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Identification of miR-34 regulatory networks in settings of disease and antimiR-therapy: Implications for treating cardiac pathology and other diseases
- (2016) Jenny Y.Y. Ooi et al. RNA Biology
- A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle
- (2016) B. R. Nelson et al. SCIENCE
- Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides
- (2016) D. M. Anderson et al. Science Signaling
- Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
- (2016) Eri H. Kobayashi et al. Nature Communications
- Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides
- (2016) D. M. Anderson et al. Science Signaling
- Therapeutically targeting mitochondrial redox signalling alleviates endothelial dysfunction in preeclampsia
- (2016) Cathal McCarthy et al. Scientific Reports
- CoQ10 Function and Role in Heart Failure and Ischemic Heart Disease
- (2015) Anita Ayer et al. Annual Review of Nutrition
- Antioxidants in Translational Medicine
- (2015) Harald H.H.W. Schmidt et al. ANTIOXIDANTS & REDOX SIGNALING
- Fanning the flames: inflammation in cardiovascular diseases
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- (2015) Keyvan Karimi Galougahi et al. EUROPEAN HEART JOURNAL
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- (2015) Luciano Cominacini et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2014) Melanie P. Chin et al. AMERICAN JOURNAL OF NEPHROLOGY
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- (2014) S. M. Tan et al. DIABETES
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- (2014) Melanie P. Chin et al. JOURNAL OF CARDIAC FAILURE
- Monoamine oxidases as sources of oxidants in the heart
- (2014) Nina Kaludercic et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Genetic Targeting or Pharmacologic Inhibition of NADPH Oxidase Nox4 Provides Renoprotection in Long-Term Diabetic Nephropathy
- (2014) J. C. Jha et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
- (2014) Edward T. Chouchani et al. NATURE
- Therapeutic targeting of microRNAs: current status and future challenges
- (2014) Zhonghan Li et al. NATURE REVIEWS DRUG DISCOVERY
- Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways
- (2014) Karina Huynh et al. PHARMACOLOGY & THERAPEUTICS
- Endothelial NADPH oxidases: which NOX to target in vascular disease?
- (2014) Grant R. Drummond et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Glutathionylation Mediates Angiotensin II–Induced eNOS Uncoupling, Amplifying NADPH Oxidase‐Dependent Endothelial Dysfunction
- (2014) Keyvan Karimi Galougahi et al. Journal of the American Heart Association
- Monoamine Oxidase B Prompts Mitochondrial and Cardiac Dysfunction in Pressure Overloaded Hearts
- (2013) Nina Kaludercic et al. ANTIOXIDANTS & REDOX SIGNALING
- Redox Modulation of Endothelial Nitric Oxide Synthase by Glutaredoxin-1 through Reversible Oxidative Post-Translational Modification
- (2013) Chun-An Chen et al. BIOCHEMISTRY
- Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis
- (2013) D.A. Lowes et al. BRITISH JOURNAL OF ANAESTHESIA
- Leptin promotes neointima formation and smooth muscle cell proliferation via NADPH oxidase activation and signalling in caveolin-rich microdomains
- (2013) Marco R. Schroeter et al. CARDIOVASCULAR RESEARCH
- NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis
- (2013) Stephen P. Gray et al. CIRCULATION
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- (2013) P. Sukumar et al. DIABETES
- Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune–inflammatory responses in diabetic Apoe −/− mice
- (2013) E. Di Marco et al. DIABETOLOGIA
- Monoamine Oxidases Are Mediators of Endothelial Dysfunction in the Mouse Aorta
- (2013) Adrian Sturza et al. HYPERTENSION
- Selective Recapitulation of Conserved and Nonconserved Regions of Putative NOXA1 Protein Activation Domain Confers Isoform-specific Inhibition of Nox1 Oxidase and Attenuation of Endothelial Cell Migration
- (2013) Daniel J. Ranayhossaini et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation
- (2013) M. E. Heid et al. JOURNAL OF IMMUNOLOGY
- Protein kinase-dependent oxidative regulation of the cardiac Na+-K+pump: evidence fromin vivoandin vitromodulation of cell signalling
- (2013) Keyvan Karimi Galougahi et al. JOURNAL OF PHYSIOLOGY-LONDON
- The Mitochondrial-Targeted Compound SS-31 Re-Energizes Ischemic Mitochondria by Interacting with Cardiolipin
- (2013) A. V. Birk et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
- (2013) Edward T Chouchani et al. NATURE MEDICINE
- Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease
- (2013) Dick de Zeeuw et al. NEW ENGLAND JOURNAL OF MEDICINE
- Peroxiredoxin 4, A Novel Circulating Biomarker for Oxidative Stress and the Risk of Incident Cardiovascular Disease and All‐Cause Mortality
- (2013) Ali Abbasi et al. Journal of the American Heart Association
- Endothelial NADPH oxidase 2: when does it matter in atherosclerosis?
- (2012) J. Haendeler et al. CARDIOVASCULAR RESEARCH
- Redox Signaling in Cardiac Physiology and Pathology
- (2012) Joseph R. Burgoyne et al. CIRCULATION RESEARCH
- Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
- (2012) B. C. Bernardo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis
- (2011) Xiaoni Kong et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Chronic Diseases: The Emerging Pandemic
- (2011) Andre Terzic et al. CTS-Clinical and Translational Science
- Mechanistic Insights Into the Therapeutic Use of High-Dose Allopurinol in Angina Pectoris
- (2011) Narasimharajapura S. Rajendra et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
- (2011) Grant R. Drummond et al. NATURE REVIEWS DRUG DISCOVERY
- Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes
- (2011) Pablo E. Pergola et al. NEW ENGLAND JOURNAL OF MEDICINE
- Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease
- (2011) Bor-Jen Lee et al. NUTRITION
- Principles of early drug discovery
- (2010) JP Hughes et al. BRITISH JOURNAL OF PHARMACOLOGY
- Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury
- (2010) Sang-Bing Ong et al. CIRCULATION
- Therapeutic Targeting of Mitochondrial Superoxide in Hypertension
- (2010) Anna E. Dikalova et al. CIRCULATION RESEARCH
- The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients
- (2010) Edward J. Gane et al. LIVER INTERNATIONAL
- A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease
- (2010) Barry J. Snow et al. MOVEMENT DISORDERS
- Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE−/− mice
- (2009) Courtney P. Judkins et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Monoamine Oxidase A–Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload
- (2009) Nina Kaludercic et al. CIRCULATION RESEARCH
- Heme oxygenase and renal disease
- (2009) Tambi Jarmi et al. CURRENT HYPERTENSION REPORTS
- Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide
- (2009) Soona Shin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway
- (2008) Wen Lin et al. BIOCHEMICAL PHARMACOLOGY
- The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide–peptidoglycan model of sepsis
- (2008) Damon A. Lowes et al. FREE RADICAL BIOLOGY AND MEDICINE
- Vitamins E and C in the Prevention of Cardiovascular Disease in Men
- (2008) Howard D. Sesso JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes
- (2008) NEW ENGLAND JOURNAL OF MEDICINE
- NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition
- (2008) Stavros Selemidis et al. PHARMACOLOGY & THERAPEUTICS
- Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant
- (2007) Sabine Heumüller et al. HYPERTENSION
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