CD36 in Alzheimer’s Disease: An Overview of Molecular Mechanisms and Therapeutic Targeting
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CD36 in Alzheimer’s Disease: An Overview of Molecular Mechanisms and Therapeutic Targeting
Authors
Keywords
-
Journal
NEUROSCIENCE
Volume 453, Issue -, Pages 301-311
Publisher
Elsevier BV
Online
2020-11-17
DOI
10.1016/j.neuroscience.2020.11.003
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation
- (2020) Elien Grajchen et al. Journal of Neuroinflammation
- Inflammatory mechanisms in neurodegeneration
- (2019) Michael R. Nichols et al. JOURNAL OF NEUROCHEMISTRY
- CD36 signaling in vascular redox stress
- (2019) Moua Yang et al. FREE RADICAL BIOLOGY AND MEDICINE
- A Unifying Hypothesis for Alzheimer’s Disease: From Plaques to Neurodegeneration
- (2019) Frances A. Edwards TRENDS IN NEUROSCIENCES
- Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease
- (2019) Maya Koronyo-Hamaoui et al. BRAIN
- 1-O-alkyl glycerophosphate-induced CD36 expression drives oxidative stress in microglial cells
- (2019) Tamotsu Tsukahara CELLULAR SIGNALLING
- Effects of β2/aβ2 on oxLDL-induced CD36 activation in THP-1 macrophages
- (2019) Chao He et al. LIFE SCIENCES
- CD36 gene polymorphism and plasma sCD36 as the risk factor in higher cholesterolemia
- (2018) M.E. Rać et al. ARCHIVES DE PEDIATRIE
- CD36 and lipid metabolism in the evolution of atherosclerosis
- (2018) Lei Zhao et al. BRITISH MEDICAL BULLETIN
- CD36 gene variants is associated with type 2 diabetes mellitus through the interaction of obesity in rural Chinese adults
- (2018) Dongdong Zhang et al. GENE
- Dynamic role of the transmembrane glycoprotein CD36 (SR-B2) in cellular fatty acid uptake and utilization
- (2018) Jan F. C. Glatz et al. JOURNAL OF LIPID RESEARCH
- The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway
- (2018) Yinquan Fang et al. Journal of Neuroinflammation
- Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis
- (2018) Andras Ladanyi et al. ONCOGENE
- Replication of a Gene-Diet Interaction at CD36 , NOS3 and PPARG in Response to Omega-3 Fatty Acid Supplements on Blood Lipids: A Double-Blind Randomized Controlled Trial
- (2018) Ju-Sheng Zheng et al. EBioMedicine
- Microglia Demonstrate Age-Dependent Interaction with Amyloid-β Fibrils
- (2018) Angela Marie Floden et al. JOURNAL OF ALZHEIMERS DISEASE
- A Randomized Placebo-Controlled Pilot Trial of Omega-3 Fatty Acids and Alpha Lipoic Acid in Alzheimer's Disease
- (2018) Lynne Shinto et al. JOURNAL OF ALZHEIMERS DISEASE
- The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer’s disease
- (2018) Sarah C. Hopp et al. Journal of Neuroinflammation
- Brain Health across the Lifespan: A Systematic Review on the Role of Omega-3 Fatty Acid Supplements
- (2018) Emma Derbyshire Nutrients
- OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice
- (2018) Chunling Yuan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Parasite Recognition and Signaling Mechanisms in Innate Immune Responses to Malaria
- (2018) D. Channe Gowda et al. Frontiers in Immunology
- The effect of oxidized phospholipids on phenotypic polarization and function of macrophages
- (2017) Vlad Serbulea et al. FREE RADICAL BIOLOGY AND MEDICINE
- Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia-mediated neurodegeneration
- (2017) Liraz Shmuel-Galia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality
- (2017) Ramesh P. Thylur et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease
- (2017) Mercy R. PrabhuDas et al. JOURNAL OF IMMUNOLOGY
- Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes
- (2017) Shannon L. Klingel et al. LIPIDS
- CD36 Deficiency Suppresses Epileptic Seizures
- (2017) Fangshuo Zheng et al. NEUROSCIENCE
- Fatty acid transporting proteins: Roles in brain development, aging, and stroke
- (2017) Wenting Zhang et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Association of Docosahexaenoic Acid Supplementation With Alzheimer Disease Stage in Apolipoprotein E ε4 Carriers
- (2017) Hussein N. Yassine et al. JAMA Neurology
- Polymorphism rs1761667 in the CD36 Gene Is Associated to Changes in Fatty Acid Metabolism and Circulating Endocannabinoid Levels Distinctively in Normal Weight and Obese Subjects
- (2017) Melania Melis et al. Frontiers in Physiology
- Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology
- (2016) Elodie Martin et al. AGING CELL
- Fatty acid-induced astrocyte ketone production and the control of food intake
- (2016) Christelle Le Foll et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Behavioral characterization of CD36 knockout mice with SHIRPA primary screen
- (2016) Shuxiao Zhang et al. BEHAVIOURAL BRAIN RESEARCH
- CD36 actions in the heart: Lipids, calcium, inflammation, repair and more?
- (2016) Nada A. Abumrad et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Omega-3 Fatty Acids and their Role in Central Nervous System - A Review
- (2016) Tomasz Wysoczański et al. CURRENT MEDICINAL CHEMISTRY
- Tet38 Efflux Pump Affects Staphylococcus aureus Internalization by Epithelial Cells through Interaction with CD36 and Contributes to Bacterial Escape from Acidic and Nonacidic Phagolysosomes
- (2016) Q. C. Truong-Bolduc et al. INFECTION AND IMMUNITY
- Impact of Omega-3 Fatty Acid Supplementation on Memory Functions in Healthy Older Adults
- (2016) Nadine Külzow et al. JOURNAL OF ALZHEIMERS DISEASE
- Activation of Peroxisome Proliferator-activated Receptor γ (PPARγ) and CD36 Protein Expression
- (2016) Xiaoxiao Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Macrophage CD36 Expression and Cellular Oxidized Low Density Lipoprotein (oxLDL) Accumulation by Tamoxifen
- (2016) Miao Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ion Channel Formation by Amyloid-β42Oligomers but Not Amyloid-β40in Cellular Membranes
- (2016) David C. Bode et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell Surface CD36 Protein in Monocyte/Macrophage Contributes to Phagocytosis during the Resolution Phase of Ischemic Stroke in Mice
- (2016) Moon-Sook Woo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus
- (2016) Maria E. Lund et al. JOURNAL OF IMMUNOLOGICAL METHODS
- CD36 Provides Host Protection AgainstKlebsiella pneumoniaeIntrapulmonary Infection by Enhancing Lipopolysaccharide Responsiveness and Macrophage Phagocytosis
- (2016) Tolani F. Olonisakin et al. JOURNAL OF INFECTIOUS DISEASES
- Higher chylomicron remnants and LDL particle numbers associate withCD36SNPs and DNA methylation sites that reduceCD36
- (2016) Latisha Love-Gregory et al. JOURNAL OF LIPID RESEARCH
- Mechanisms of Aβ Clearance and Degradation by Glial Cells
- (2016) Miriam Ries et al. Frontiers in Aging Neuroscience
- Leishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation
- (2016) Kendi Okuda et al. PLoS Pathogens
- CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium
- (2016) André Machado Xavier et al. Scientific Reports
- Intakes of fish and polyunsaturated fatty acids and mild-to-severe cognitive impairment risks: a dose-response meta-analysis of 21 cohort studies1–3
- (2015) Yu Zhang et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Prostaglandin E2 Receptor Subtype 2 Regulation of Scavenger Receptor CD36 Modulates Microglial Aβ42 Phagocytosis
- (2015) Xianwu Li et al. AMERICAN JOURNAL OF PATHOLOGY
- Therapeutic effects of glatiramer acetate and grafted CD115+monocytes in a mouse model of Alzheimer’s disease
- (2015) Yosef Koronyo et al. BRAIN
- Apoptotic cell recognition receptors and scavenger receptors
- (2015) Kristen K. Penberthy et al. IMMUNOLOGICAL REVIEWS
- Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake
- (2015) Xiaoxiao Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD36 Is Essential for Regulation of the Host Innate Response toStaphylococcus aureusα-Toxin–Mediated Dermonecrosis
- (2015) Moriah J. Castleman et al. JOURNAL OF IMMUNOLOGY
- Dietary Patterns and Risk of Dementia: a Systematic Review and Meta-Analysis of Cohort Studies
- (2015) Lei Cao et al. MOLECULAR NEUROBIOLOGY
- Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma
- (2015) Aritro Nath et al. Scientific Reports
- Structure-Function of CD36 and Importance of Fatty Acid Signal Transduction in Fat Metabolism
- (2014) Marta Yanina Pepino et al. Annual Review of Nutrition
- CD36 Upregulation Mediated by Intranasal LV-NRF2 Treatment Mitigates Hypoxia-Induced Progression of Alzheimer's-Like Pathogenesis
- (2014) Chun-Yan Wang et al. ANTIOXIDANTS & REDOX SIGNALING
- Commentary on Myers et al.: Growing role of the innate immunity receptor CD36 in central nervous system diseases
- (2014) Lidia Garcia-Bonilla et al. EXPERIMENTAL NEUROLOGY
- Mitochondrial Dysfunction and Decrease in Body Weight of a Transgenic Knock-in Mouse Model for TDP-43
- (2014) Carola Stribl et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-4-Induced Selective Clearance of Oligomeric -Amyloid Peptide1-42 by Rat Primary Type 2 Microglia
- (2014) E. Shimizu et al. JOURNAL OF IMMUNOLOGY
- Role of Human CD36 in Bacterial Recognition, Phagocytosis, and Pathogen-Induced JNK-Mediated Signaling
- (2014) I. N. Baranova et al. JOURNAL OF IMMUNOLOGY
- Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis
- (2014) Deborah Doens et al. Journal of Neuroinflammation
- Omega-3 fatty acids and brain resistance to ageing and stress: Body of evidence and possible mechanisms
- (2013) I. Denis et al. AGEING RESEARCH REVIEWS
- DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial
- (2013) Welma Stonehouse et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling
- (2013) Ming-Sheng Zhou et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Molecular Basis of Antiangiogenic Thrombospondin-1 Type 1 Repeat Domain Interactions With CD36
- (2013) Philip A. Klenotic et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- FAT/CD36: A Major Regulator of Neuronal Fatty Acid Sensing and Energy Homeostasis in Rats and Mice
- (2013) Christelle Le Foll et al. DIABETES
- CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
- (2013) Frederick J Sheedy et al. NATURE IMMUNOLOGY
- Innate immunity receptor CD36 promotes cerebral amyloid angiopathy
- (2013) L. Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia
- (2012) Eunhee Kim et al. ANNALS OF NEUROLOGY
- CD36 as a Therapeutic Target for Endothelial Dysfunction in Stroke
- (2012) Sunghee Cho CURRENT PHARMACEUTICAL DESIGN
- Functional consequences of CD36 downregulation by TLR signals
- (2012) Carlos Zamora et al. CYTOKINE
- CD36 is Involved in Astrocyte Activation and Astroglial Scar Formation
- (2012) Yi Bao et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Amyloid-β-Induced Astrocytic Phagocytosis is Mediated by CD36, CD47 and RAGE
- (2012) Raasay S. Jones et al. Journal of Neuroimmune Pharmacology
- PPAR /RXR -Induced and CD36-Mediated Microglial Amyloid- Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice
- (2012) M. Yamanaka et al. JOURNAL OF NEUROSCIENCE
- Context Dependent Role of the CD36 - Thrombospondin - Histidine-Rich Glycoprotein Axis in Tumor Angiogenesis and Growth
- (2012) James Scott Hale et al. PLoS One
- Docosahexaenoic acid-concentrated fish oil supplementation in subjects with mild cognitive impairment (MCI): a 12-month randomised, double-blind, placebo-controlled trial
- (2012) Lai Kuan Lee et al. PSYCHOPHARMACOLOGY
- Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime
- (2011) Paola Gamba et al. AGING CELL
- Polymorphism of the CD36 Gene and Cardiovascular Risk Factors in Patients with Coronary Artery Disease Manifested at a Young Age
- (2011) Monika Ewa Rać et al. BIOCHEMICAL GENETICS
- Alzheimer's disease: Cholesterol a menace?
- (2011) Anila Mathew et al. BRAIN RESEARCH BULLETIN
- A High Content Drug Screen Identifies Ursolic Acid as an Inhibitor of Amyloid β Protein Interactions with Its Receptor CD36
- (2011) Kim Wilkinson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkin reinvents itself to regulate fatty acid metabolism by tagging CD36
- (2011) Nada A. Abumrad et al. JOURNAL OF CLINICAL INVESTIGATION
- Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
- (2011) Kye-Young Kim et al. JOURNAL OF CLINICAL INVESTIGATION
- Pathogenic Role of Scavenger Receptor CD36 in the Metabolic Syndrome and Diabetes
- (2011) David J. Kennedy et al. Metabolic Syndrome and Related Disorders
- Mechanism mediating oligomeric Aβ clearance by naïve primary microglia
- (2011) Cheng-Ning Yang et al. NEUROBIOLOGY OF DISEASE
- Soluble CD36− a marker of the (pathophysiological) role of CD36 in the metabolic syndrome?
- (2011) Debby P.Y. Koonen et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- Silencing of either SR-A or CD36 reduces atherosclerosis in hyperlipidaemic mice and reveals reciprocal upregulation of these receptors
- (2010) P. I. Makinen et al. CARDIOVASCULAR RESEARCH
- Expression of adhesion antigens of human bone marrow megakaryocytes, circulating megakaryocytes and blood platelets
- (2010) Elisabeth C. M. Pampus et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease
- (2010) Joseph F. Quinn et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology
- (2010) Luis Escribano et al. NEUROPSYCHOPHARMACOLOGY
- Inflammation, atherosclerosis, and arterial thrombosis: Role of the scavenger receptor CD36
- (2009) R. L. SILVERSTEIN CLEVELAND CLINIC JOURNAL OF MEDICINE
- Neuronal expression of Cd36, Cd44, and Cd83 antigen transcripts maps to distinct and specific murine brain circuits
- (2009) Isaias Glezer et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Desacyl-ghrelin and synthetic GH-secretagogues modulate the production of inflammatory cytokines in mouse microglia cells stimulated by β-amyloid fibrils
- (2009) Ilaria Bulgarelli et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol
- (2008) Latisha Love-Gregory et al. HUMAN MOLECULAR GENETICS
- Amyloid β-Protein Assembly and Alzheimer Disease
- (2008) Robin Roychaudhuri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microglial Dysfunction and Defective -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
- (2008) S. E. Hickman et al. JOURNAL OF NEUROSCIENCE
- Polymorphisms in the CD36 gene modulate the ability of fish oil supplements to lower fasting plasma triacyl glycerol and raise HDL cholesterol concentrations in healthy middle-aged men
- (2008) Jacqueline Madden et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Hematoma Resolution as a Therapeutic Target: The Role of Microglia/Macrophages
- (2008) X. Zhao et al. STROKE
- Mechanisms of Aβ mediated neurodegeneration in Alzheimer's disease
- (2007) Peter J. Crouch et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now