Mitochondrial dysfunction, mitophagy, and role of dynamin‐related protein 1 in Alzheimer's disease
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Title
Mitochondrial dysfunction, mitophagy, and role of dynamin‐related protein 1 in Alzheimer's disease
Authors
Keywords
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Journal
JOURNAL OF NEUROSCIENCE RESEARCH
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2021-01-20
DOI
10.1002/jnr.24781
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Note: Only part of the references are listed.- Drp1 overexpression induces desmin disassembling and drives kinesin-1 activation promoting mitochondrial trafficking in skeletal muscle
- (2020) Matteo Giovarelli et al. CELL DEATH AND DIFFERENTIATION
- Mitochondrial MicroRNAs in Aging and Neurodegenerative Diseases
- (2020) Albin John et al. Cells
- MicroRNAs Dysregulation and Mitochondrial Dysfunction in Neurodegenerative Diseases
- (2020) Mariano Catanesi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Defective mitophagy in Alzheimer’s disease
- (2020) Jangampalli Adi Pradeepkiran et al. AGEING RESEARCH REVIEWS
- The role of synaptic microRNAs in Alzheimer's disease
- (2020) Subodh Kumar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
- (2019) Evandro F. Fang et al. NATURE NEUROSCIENCE
- Mitophagy and NAD+ inhibit Alzheimer disease
- (2019) Evandro F. Fang Autophagy
- Small molecules as therapeutic drugs for Alzheimer's disease
- (2019) Darryll M.A. Oliver et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Amyloid Beta and MicroRNAs in Alzheimer’s Disease
- (2019) Nnana Amakiri et al. Frontiers in Neuroscience
- Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease
- (2019) P. Hemachandra Reddy et al. Cells
- Mitophagy Failure in APP and Tau Overexpression Model of Alzheimer’s Disease
- (2019) Patricia Martín-Maestro et al. JOURNAL OF ALZHEIMERS DISEASE
- Novel MicroRNA-455-3p and its protective effects against abnormal APP processing and amyloid beta toxicity in Alzheimer's disease
- (2019) Subodh Kumar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Dynamics of Dynamin-Related Protein 1 in Alzheimer’s Disease and Other Neurodegenerative Diseases
- (2019) Darryll Oliver et al. Cells
- Nitration of Drp1 provokes mitophagy activation mediating neuronal injury in experimental autoimmune encephalomyelitis
- (2019) Wenting Li et al. FREE RADICAL BIOLOGY AND MEDICINE
- A New Discovery of MicroRNA-455-3p in Alzheimer’s Disease
- (2019) Subodh Kumar et al. JOURNAL OF ALZHEIMERS DISEASE
- Mitochondrial MiRNA in Cardiovascular Function and Disease
- (2019) Rui Song et al. Cells
- MicroRNA: A new generation therapeutic target in diabetic nephropathy
- (2018) Saikat Dewanjee et al. BIOCHEMICAL PHARMACOLOGY
- Mitochondrial dysfunction and neurodegenerative proteinopathies: mechanisms and prospects for therapeutic intervention
- (2018) Thomas Briston et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer’s disease
- (2018) P Hemachandra Reddy et al. HUMAN MOLECULAR GENETICS
- Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer’s disease
- (2018) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Autophagy balances mtDNA synthesis and degradation by DNA polymerase POLG during starvation
- (2018) Tânia Catarina Medeiros et al. JOURNAL OF CELL BIOLOGY
- PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction
- (2018) Yun Sun Park et al. TOXICOLOGY LETTERS
- Methods for assessing mitochondrial quality control mechanisms and cellular consequences in cell culture
- (2018) Matthew Redmann et al. Redox Biology
- Autophagy and Mitochondria: Targets in Neurodegenerative Disorders
- (2018) Ashutosh Kumar et al. CNS & Neurological Disorders-Drug Targets
- Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity
- (2018) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Inhibitors of Mitochondrial Fission as a Therapeutic Strategy for Diseases with Oxidative Stress and Mitochondrial Dysfunction
- (2018) P. Hemachandra Reddy JOURNAL OF ALZHEIMERS DISEASE
- Autophagic dysfunction in Alzheimer’s disease: Cellular and molecular mechanistic approaches to halt Alzheimer’s pathogenesis
- (2018) Md. Sahab Uddin et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer’s disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities
- (2017) Chandra Sekhar Kuruva et al. HUMAN MOLECULAR GENETICS
- Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer’s disease
- (2017) P. Hemachandra Reddy et al. HUMAN MOLECULAR GENETICS
- Therapeutics of Neurotransmitters in Alzheimer’s Disease
- (2017) Ramesh Kandimalla et al. JOURNAL OF ALZHEIMERS DISEASE
- Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model
- (2017) Seung Hyun Baek et al. JOURNAL OF NEUROSCIENCE
- Mitophagy in neurodegeneration and aging
- (2017) Elayne M. Fivenson et al. NEUROCHEMISTRY INTERNATIONAL
- Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms
- (2017) Jesse S. Kerr et al. TRENDS IN NEUROSCIENCES
- Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson’s disease
- (2017) Brianada Koentjoro et al. Scientific Reports
- Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy
- (2016) Ming Chen et al. Autophagy
- Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis
- (2016) Ramesh Kandimalla et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease
- (2016) Xiangling Yin et al. HUMAN MOLECULAR GENETICS
- Role of microRNAs on the Regulation of Mitochondrial Biogenesis and Insulin Signaling in Skeletal Muscle
- (2016) Tanes I. Lima et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin
- (2016) Yu Hu et al. Oncotarget
- Molecular mechanisms underlying PINK1 and Parkin catalyzed ubiquitylation of substrates on damaged mitochondria
- (2015) Fumika Koyano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Understanding Aspects of Aluminum Exposure in Alzheimer's Disease Development
- (2015) Ramesh Kandimalla et al. BRAIN PATHOLOGY
- The mitochondrial protein BNIP3L is the substrate of PARK2 and mediates mitophagy in PINK1/PARK2 pathway
- (2015) Feng Gao et al. HUMAN MOLECULAR GENETICS
- Mitochondrial division inhibitor 1 protects against mutant huntingtin-induced abnormal mitochondrial dynamics and neuronal damage in Huntington's disease
- (2015) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?
- (2015) Jaime Ross et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- Compromised autophagy and neurodegenerative diseases
- (2015) Fiona M. Menzies et al. NATURE REVIEWS NEUROSCIENCE
- NLRP3 inflammasome activation by mitochondrial reactive oxygen species plays a key role in long-term cognitive impairment induced by paraquat exposure
- (2015) Liuji Chen et al. NEUROBIOLOGY OF AGING
- Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice
- (2015) Marissa J. Schafer et al. NEUROBIOLOGY OF AGING
- Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation
- (2015) T Touvier et al. Cell Death & Disease
- Shared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer’s Disease: Impacts on Cognitive Decline
- (2015) Jennifer Walker et al. Nutrients
- Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance
- (2014) Lori Buhlman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
- (2014) F Strappazzon et al. CELL DEATH AND DIFFERENTIATION
- Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain
- (2014) Yusuke Kageyama et al. EMBO JOURNAL
- Role of Glucose Metabolism and ATP in Maintaining PINK1 Levels during Parkin-mediated Mitochondrial Damage Responses
- (2014) Schuyler Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-137 Is a Novel Hypoxia-responsive MicroRNA That Inhibits Mitophagy via Regulation of Two Mitophagy Receptors FUNDC1 and NIX
- (2014) Wen Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitofusin 1 Is Negatively Regulated by MicroRNA 140 in Cardiomyocyte Apoptosis
- (2014) J. Li et al. MOLECULAR AND CELLULAR BIOLOGY
- MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin
- (2014) Jina Yun et al. eLife
- The Role of microRNAs in Mitochondria: Small Players Acting Wide
- (2014) Filipe Duarte et al. Genes
- PINK1 is degraded through the N-end rule pathway
- (2013) Koji Yamano et al. Autophagy
- Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance
- (2013) S Dalleau et al. CELL DEATH AND DIFFERENTIATION
- miR-761 regulates the mitochondrial network by targeting mitochondrial fission factor
- (2013) Bo Long et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hexokinase activity is required for recruitment of parkin to depolarized mitochondria
- (2013) Melissa K. McCoy et al. HUMAN MOLECULAR GENETICS
- Parkin-catalyzed Ubiquitin-Ester Transfer Is Triggered by PINK1-dependent Phosphorylation
- (2013) Masahiro Iguchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adaptive Changes in the Neuronal Proteome: Mitochondrial Energy Production, Endoplasmic Reticulum Stress, and Ribosomal Dysfunction in the Cellular Response to Metabolic Stress
- (2013) Abigail G Herrmann et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
- (2013) E. S. Vincow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Ubiquitin-Proteasome System and the Autophagic-Lysosomal System in Alzheimer Disease
- (2013) Y. Ihara et al. Cold Spring Harbor Perspectives in Medicine
- CSF p-Tau levels in the prediction of Alzheimer's disease
- (2013) R. J. L. Kandimalla et al. Biology Open
- Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer’s disease
- (2012) A-Ryeong Gwon et al. AGING CELL
- Dynamin-related protein 1 heterozygote knockout mice do not have synaptic and mitochondrial deficiencies
- (2012) Maria Manczak et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease
- (2012) Mark P. Mattson Cell Metabolism
- Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- Mitochondrial dynamics in neurodegeneration
- (2012) Kie Itoh et al. TRENDS IN CELL BIOLOGY
- Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control
- (2011) Derek P. Narendra et al. ANTIOXIDANTS & REDOX SIGNALING
- Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease
- (2011) P. Hemachandra Reddy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
- (2011) Elena Miñones-Moyano et al. HUMAN MOLECULAR GENETICS
- Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
- (2011) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Ubiquitin-dependent mitochondrial protein degradation
- (2011) Jin-Mi Heo et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
- (2011) Ligia C. Gomes et al. NATURE CELL BIOLOGY
- Protective efficacy of mitochondrial targeted antioxidant MitoQ against dichlorvos induced oxidative stress and cell death in rat brain
- (2011) Willayat Yousuf Wani et al. NEUROPHARMACOLOGY
- Pre-microRNA and Mature microRNA in Human Mitochondria
- (2011) Eric Barrey et al. PLoS One
- Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
- (2011) A. S. Rambold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Tau Protein in Alzheimerʼs Disease
- (2010) Cheng-Xin Gong et al. DRUGS & AGING
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1
- (2010) Jian-Xun Wang et al. NATURE MEDICINE
- How does diabetes accelerate Alzheimer disease pathology?
- (2010) Catrina Sims-Robinson et al. Nature Reviews Neurology
- miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway
- (2010) Jincheng Li et al. PLoS Genetics
- The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
- (2009) Junko Wakabayashi et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
- (2009) Naotada Ishihara et al. NATURE CELL BIOLOGY
- Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view
- (2008) Gilad Twig et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Essential role for Nix in autophagic maturation of erythroid cells
- (2008) Hector Sandoval et al. NATURE
- Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
- (2008) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
- (2008) P. Hemachandra Reddy et al. TRENDS IN MOLECULAR MEDICINE
- Aβ inhibits the proteasome and enhances amyloid and tau accumulation
- (2007) Bertrand P. Tseng et al. NEUROBIOLOGY OF AGING
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