Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer’s disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer’s disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities
Authors
Keywords
-
Journal
HUMAN MOLECULAR GENETICS
Volume 26, Issue 17, Pages 3375-3395
Publisher
Oxford University Press (OUP)
Online
2017-06-09
DOI
10.1093/hmg/ddx226
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer’s disease
- (2017) P. Hemachandra Reddy et al. HUMAN MOLECULAR GENETICS
- Mitochondria-Division Inhibitor 1 Protects Against Amyloid-β induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer’s Disease
- (2017) P. Hemachandra Reddy et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid-β and Mitochondria in Aging and Alzheimer's Disease: Implications for Synaptic Damage and Cognitive Decline
- (2017) P. Hemachandra Reddy et al. JOURNAL OF ALZHEIMERS DISEASE
- The Alzheimer's Disease Mitochondrial Cascade Hypothesis
- (2017) Russell H. Swerdlow et al. JOURNAL OF ALZHEIMERS DISEASE
- Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons
- (2017) Maria Manczak et al. JOURNAL OF ALZHEIMERS DISEASE
- Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis
- (2016) Ramesh Kandimalla et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Novel Coumarin-Containing Aminophosphonatesas Antitumor Agent: Synthesis, Cytotoxicity, DNA-Binding and Apoptosis Evaluation
- (2015) Ya-Jun Li et al. MOLECULES
- Amino Acid Esters Substituted Phosphorylated Emtricitabine and Didanosine Derivatives as Antiviral and Anticancer Agents
- (2014) Kuruva Chandra Sekhar et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both -Amyloid Production and Clearance
- (2013) Z. Zhu et al. JOURNAL OF NEUROSCIENCE
- Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- The peripheral messenger RNA expression of glycogen synthase kinase-3β genes in Alzheimer's disease patients: a preliminary study
- (2012) Jian-Hua SHENG et al. Psychogeriatrics
- Mitochondria and Cell Bioenergetics: Increasingly Recognized Components and a Possible Etiologic Cause of Alzheimer's Disease
- (2011) Russell H. Swerdlow ANTIOXIDANTS & REDOX SIGNALING
- Synaptic Mitochondrial Pathology in Alzheimer's Disease
- (2011) Heng Du et al. ANTIOXIDANTS & REDOX SIGNALING
- Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics
- (2011) P. Hemachandra Reddy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease
- (2011) P. Hemachandra Reddy BRAIN RESEARCH
- Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
- (2011) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
- (2010) Gunnar K. Gouras et al. ACTA NEUROPATHOLOGICA
- Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases
- (2010) P. Hemachandra Reddy et al. BRAIN RESEARCH REVIEWS
- Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
- (2010) H. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease
- (2009) P. Hemachandra Reddy EXPERIMENTAL NEUROLOGY
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
- (2009) J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
- (2008) Ann Cassidy-Stone et al. DEVELOPMENTAL CELL
- Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
- (2008) Heng Du et al. NATURE MEDICINE
- Amyloid- overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
- (2008) X. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The amyloid -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
- (2008) C. A. Hansson Petersen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An overview of stereoselective synthesis of α-aminophosphonic acids and derivatives
- (2008) Mario Ordóñez et al. TETRAHEDRON
- Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
- (2008) P. Hemachandra Reddy et al. TRENDS IN MOLECULAR MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now