Role of Host-Mediated Post-Translational Modifications (PTMs) in RNA Virus Pathogenesis

A SNARE geranylgeranyltransferase essential for the organization of the Golgi apparatus

(2020) Ryutaro Shirakawa et al.   EMBO JOURNAL

The impact of PARPs and ADP-ribosylation on inflammation and host–pathogen interactions

(2020) Anthony R. Fehr et al.   GENES & DEVELOPMENT

PARP1 enhances influenza A virus propagation by facilitating degradation of host type I interferon receptor

(2020) Chuan Xia et al.   JOURNAL OF VIROLOGY

Palmitoylated cysteines in Chikungunya virus nsP1 are critical for targeting to cholesterol-rich plasma membrane microdomains with functional consequences for viral genome replication

(2020) William Bakhache et al.   JOURNAL OF VIROLOGY

TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Vesicular Stomatitis Virus Infection

(2020) Girish Patil et al.   Viruses-Basel

NS5 Conservative Site Is Required for Zika Virus to Restrict the RIG-I Signaling

(2020) Aixin Li et al.   Frontiers in Immunology

Env Exceptionalism: Why Are HIV-1 Env Glycoproteins Atypical Immunogens?

(2020) P.J. Klasse et al.   Cell Host & Microbe

TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination

(2020) Qingchen Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nonproteolytic K29-Linked Ubiquitination of the PB2 Replication Protein of Influenza A Viruses by Proviral Cullin 4-Based E3 Ligases

(2020) Marwah Karim et al.   mBio

Characterization and noncovalent inhibition of the deubiquitinase and deISGylase activity of SARS-CoV-2 papain-like protease

(2020) Brendan T Freitas et al.   ACS Infectious Diseases

Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming

(2020) Meike Kespohl et al.   Science Advances

Myristoylation of EV71 VP4 is Essential for Infectivity and Interaction with Membrane Structure

(2020) Jiaming Cao et al.   VIROLOGICA SINICA

Exploring the Influence of Cell Metabolism on Cell Fate through Protein Post-translational Modifications

(2020) Oscar A. Tarazona et al.   DEVELOPMENTAL CELL

ISGylation of hepatitis C virus NS5A protein promotes viral RNA replication via the recruitment of cyclophilin A

(2020) Takayuki Abe et al.   JOURNAL OF VIROLOGY

NS5 Sumoylation Directs Nuclear Responses that Permit Zika Virus to Persistently Infect Human Brain Microvascular Endothelial Cells

(2020) Jonas N. Conde et al.   JOURNAL OF VIROLOGY

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

(2020) Donghyuk Shin et al.   NATURE

MARCH8 Inhibits Ebola Virus Glycoprotein, Human Immunodeficiency Virus Type 1 Envelope Glycoprotein, and Avian Influenza Virus H5N1 Hemagglutinin Maturation

(2020) Changqing Yu et al.   mBio

SARS-CoV-2 N protein antagonizes type I interferon signaling by suppressing phosphorylation and nuclear translocation of STAT1 and STAT2

(2020) Jingfang Mu et al.   Cell Discovery

TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb

(2019) Xiancai Ma et al.   eLife

The Molecular Basis of Viral Inhibition of IRF- and STAT-Dependent Immune Responses

(2019) Hao-Sen Chiang et al.   Frontiers in Immunology

Inhibition of N -myristoyltransferase1 affects dengue virus replication

(2019) San Suwanmanee et al.   MicrobiologyOpen

MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment

(2019) Sathish Kumar et al.   Cell Reports

Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation

(2019) Hashim Ali et al.   Nature Communications

Exploitation of glycosylation in enveloped virus pathobiology

(2019) Yasunori Watanabe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Tat expression led to increased histone 3 tri-methylation at lysine 27 and contributed to HIV latency in astrocytes through regulation of MeCP2 and Ezh2 expression

(2019) Ying Liu et al.   JOURNAL OF NEUROVIROLOGY

Envelope Protein Glycosylation Mediates Zika Virus Pathogenesis

(2019) Derek L. Carbaugh et al.   JOURNAL OF VIROLOGY

The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression

(2019) Matthew E. Grunewald et al.   PLoS Pathogens

ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP

(2019) Tingting Guo et al.   Nature Microbiology

Control of antiviral innate immune response by protein geranylgeranylation

(2019) Shigao Yang et al.   Science Advances

Zika virus circumvents host innate immunity by targeting the adaptor proteins MAVS and MITA

(2019) Wenjiao Li et al.   FASEB JOURNAL

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

(2019) Abhilash I. Chiramel et al.   Cell Reports

Neddylation Facilitates the Antiviral Response in Zebrafish

(2019) Guangqing Yu et al.   Frontiers in Immunology

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

(2019) Nora Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication

(2019) Ting Pan et al.   eLife

Ebola virus replication is regulated by the phosphorylation of viral protein VP35

(2019) Lin Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of the Ebola Virus VP24 Protein by SUMO

(2019) Santiago Vidal et al.   JOURNAL OF VIROLOGY

Palmitoylation of Hepatitis C Virus NS2 Regulates Its Subcellular Localization and NS2-NS3 Autocleavage

(2019) Ming-Jhan Wu et al.   JOURNAL OF VIROLOGY

RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions

(2019) Johannes Schwerk et al.   NATURE IMMUNOLOGY

Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies

(2018) Hong Jiang et al.   CHEMICAL REVIEWS

Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5

(2018) Dai Hatakeyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Influenza A Virus Infection

(2018) Girish Patil et al.   JOURNAL OF VIROLOGY

Insights into the biogenesis, function, and regulation of ADP-ribosylation

(2018) Michael S Cohen et al.   Nature Chemical Biology

STING-dependent translation inhibition restricts RNA virus replication

(2018) Kate M. Franz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PARP12suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins

(2018) Lili Li et al.   Science Signaling

Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis

(2018) Anthony R. Fehr et al.   TRENDS IN MICROBIOLOGY

Inhibition of neddylation pathway represses influenza virus replication and pro-inflammatory responses

(2018) Haiwei Sun et al.   VIROLOGY

The coronavirus nucleocapsid protein is ADP-ribosylated

(2018) Matthew E. Grunewald et al.   VIROLOGY

K48-linked polyubiquitination of dengue virus NS1 protein inhibits its interaction with the viral partner NS4B

(2018) Maria Isabel Giraldo et al.   VIRUS RESEARCH

PARP12suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins

(2018) Lili Li et al.   Science Signaling

Protein Palmitoylation and Its Role in Bacterial and Viral Infections

(2018) Justyna Sobocińska et al.   Frontiers in Immunology

Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1‐caspase‐1 axis

(2018) Yanyan Zheng et al.   EMBO JOURNAL

Epigenetic control of influenza virus: role of H3K79 methylation in interferon-induced antiviral response

(2018) Laura Marcos-Villar et al.   Scientific Reports

Cellular N-myristoyltransferases play a crucial picornavirus genus-specific role in viral assembly, virion maturation, and infectivity

(2018) Irena Corbic Ramljak et al.   PLoS Pathogens

Interferon-stimulated TRIM69 interrupts dengue virus replication by ubiquitinating viral nonstructural protein 3

(2018) Kezhen Wang et al.   PLoS Pathogens

Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection

(2018) Valerie J. Kinchen et al.   Cell Host & Microbe

HDAC6 restricts influenza A virus by deacetylation of the RNA polymerase PA subunit

(2018) Huan Chen et al.   JOURNAL OF VIROLOGY

ADP-ribosyl–binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication

(2018) Rachy Abraham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of Type I Interferon Signaling by Flavivirus NS5

(2018) Stephanie Thurmond et al.   Viruses-Basel

Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth

(2018) Kshitij Wagh et al.   Cell Reports

Palmitoylation mediates membrane association of hepatitis E virus ORF3 protein and is required for infectious particle secretion

(2018) Jérôme Gouttenoire et al.   PLoS Pathogens

The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review)

(2017) Fatima Ardito et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis

(2017) Chien-Yi Lu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulating STING in health and disease

(2017) Yang Li et al.   Journal of Inflammation-London

Structure and Function of Viral Deubiquitinating Enzymes

(2017) Ben A. Bailey-Elkin et al.   JOURNAL OF MOLECULAR BIOLOGY

Viral Epitranscriptomics

(2017) Edward M. Kennedy et al.   JOURNAL OF VIROLOGY

Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response

(2017) Dongming Zhao et al.   JOURNAL OF VIROLOGY

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication

(2017) Preeti Bharaj et al.   JOURNAL OF VIROLOGY

Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency

(2017) Zheng Zhang et al.   NUCLEIC ACIDS RESEARCH

Protein Posttranslational Modifications: Roles in Aging and Age-Related Disease

(2017) Ana L. Santos et al.   Oxidative Medicine and Cellular Longevity

CNOT4-Mediated Ubiquitination of Influenza A Virus Nucleoprotein Promotes Viral RNA Replication

(2017) Yu-Chen Lin et al.   mBio

Role of influenza A virus NP acetylation on viral growth and replication

(2017) Sebastian Giese et al.   Nature Communications

NEDDylation of PB2 Reduces Its Stability and Blocks the Replication of Influenza A Virus

(2017) Tinghong Zhang et al.   Scientific Reports

Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease

(2017) Florine E.M. Scholte et al.   Cell Reports

Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation

(2017) Jiaoyu Shan et al.   PLoS Pathogens

Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6

(2017) Jie Zan et al.   Frontiers in Cellular and Infection Microbiology

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

(2017) Sebastian Aguirre et al.   Nature Microbiology

HIV-1 matrix-31 membrane binding peptide interacts differently with membranes containing PS vs . PI(4,5)P 2

(2016) Lauren O'Neil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The cGAS-STING Defense Pathway and Its Counteraction by Viruses

(2016) Zhe Ma et al.   Cell Host & Microbe

Ubiquitin modifications

(2016) Kirby N Swatek et al.   CELL RESEARCH

Threonine 80 phosphorylation of non-structural protein 1 regulates the replication of influenza A virus by reducing the binding affinity with RIG-I

(2016) Weinan Zheng et al.   CELLULAR MICROBIOLOGY

Phosphorylation of influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity

(2016) Omer Abid Kathum et al.   CELLULAR MICROBIOLOGY

HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I

(2016) S. J. Choi et al.   EMBO JOURNAL

Post-Translational Modification Control of Innate Immunity

(2016) Juan Liu et al.   IMMUNITY

Histone deacetylase inhibitors suppress RSV infection and alleviate virus-induced airway inflammation

(2016) Qiuqin Feng et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Poly(ADP-ribose) polymerase-1 silences retroviruses independently of viral DNA integration or heterochromatin formation

(2016) Denisse A. Gutierrez et al.   JOURNAL OF GENERAL VIROLOGY

Role of envelope N-linked glycosylation in Ross River virus virulence and transmission

(2016) Michelle A. Nelson et al.   JOURNAL OF GENERAL VIROLOGY

Secreted NS1 Protects Dengue Virus from Mannose-Binding Lectin–Mediated Neutralization

(2016) Somchai Thiemmeca et al.   JOURNAL OF IMMUNOLOGY

HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual

(2016) Karen P. Coss et al.   JOURNAL OF VIROLOGY

SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication

(2016) Yan Liu et al.   JOURNAL OF VIROLOGY

Viral Macro Domains Reverse Protein ADP-Ribosylation

(2016) Changqing Li et al.   JOURNAL OF VIROLOGY

Ubiquitination Upregulates Influenza Virus Polymerase Function

(2016) James Kirui et al.   JOURNAL OF VIROLOGY

Palmitoylation of Sindbis Virus TF Protein Regulates Its Plasma Membrane Localization and Subsequent Incorporation into Virions

(2016) Jolene Ramsey et al.   JOURNAL OF VIROLOGY

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease

(2016) Miklós Békés et al.   MOLECULAR CELL

Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

(2016) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins

(2016) Chen Zhao et al.   Nature Communications

APOBEC3G-Mediated G-to-A Hypermutation of the HIV-1 Genome: The Missing Link in Antiviral Molecular Mechanisms

(2016) Ayaka Okada et al.   Frontiers in Microbiology

SARS hCoV papain-like protease is a unique Lys48linkage-specific di-distributive deubiquitinating enzyme

(2015) Miklós Békés et al.   BIOCHEMICAL JOURNAL

TRIM5  requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription

(2015) A. J. Fletcher et al.   EMBO JOURNAL

The hepatitis E virus ORF1 ‘X-domain’ residues form a putative macrodomain protein/Appr-1″-pase catalytic-site, critical for viral RNA replication

(2015) Mohammad Khalid Parvez   GENE

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization

(2015) Bastian Thaa et al.   JOURNAL OF VIROLOGY

Biology of Poly(ADP-Ribose) Polymerases: The Factotums of Cell Maintenance

(2015) Peter Bai   MOLECULAR CELL

Antigen-presenting cells look within during influenza infection

(2015) Justine D Mintern et al.   NATURE MEDICINE

Protein neddylation: beyond cullin–RING ligases

(2015) Radoslav I. Enchev et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Battle between influenza A virus and a newly identified antiviral activity of the PARP-containing ZAPL protein

(2015) Chien-Hung Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Single Stranded RNA Virus Proteins and Potential for Novel Therapeutic Strategies

(2015) Forrest Keck et al.   Viruses-Basel

Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response

(2015) Yong Ran et al.   Journal of Molecular Cell Biology

Global Reprogramming of Host SUMOylation during Influenza Virus Infection

(2015) Patricia Domingues et al.   Cell Reports

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Interferon-mediated ISG15 conjugation restricts dengue virus 2 replication

(2014) Takayuki Hishiki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ubiquitin-Like Protein ISG15 (Interferon-Stimulated Gene of 15 kDa) in Host Defense Against Heart Failure in a Mouse Model of Virus-Induced Cardiomyopathy

(2014) Anna Rahnefeld et al.   CIRCULATION

Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression

(2014) Ben A. Bailey-Elkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Deacetylase 6 Inhibits Influenza A Virus Release by Downregulating the Trafficking of Viral Components to the Plasma Membrane via Its Substrate, Acetylated Microtubules

(2014) M. Husain et al.   JOURNAL OF VIROLOGY

Sumoylation of Influenza A Virus Nucleoprotein Is Essential for Intracellular Trafficking and Virus Growth

(2014) Q. Han et al.   JOURNAL OF VIROLOGY

Ubiquitination in disease pathogenesis and treatment

(2014) Doris Popovic et al.   NATURE MEDICINE

IFITM-Family Proteins: The Cell's First Line of Antiviral Defense

(2014) Charles C. Bailey et al.   Annual Review of Virology

Understanding MHC Class I Presentation of Viral Antigens by Human Dendritic Cells as a Basis for Rational Design of Therapeutic Vaccines

(2014) Nadine van Montfoort et al.   Frontiers in Immunology

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

Effect of posttranslational modifications on enzyme function and assembly

(2013) Helena Ryšlavá et al.   Journal of Proteomics

Palmitoylation on Conserved and Nonconserved Cysteines of Murine IFITM1 Regulates Its Stability and Anti-Influenza A Virus Activity

(2013) J. C. Hach et al.   JOURNAL OF VIROLOGY

Inhibition of CUL4A Neddylation Causes a Reversible Block to SAMHD1-Mediated Restriction of HIV-1

(2013) H. Hofmann et al.   JOURNAL OF VIROLOGY

Interplay between viruses and host sumoylation pathways

(2013) Roger D. Everett et al.   NATURE REVIEWS MICROBIOLOGY

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

(2013) Anna M. Mielech et al.   VIROLOGY

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G

(2013) David J. Stanley et al.   PLoS Pathogens

Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling

(2013) Juliet Morrison et al.   PLoS Pathogens

Ubiquitin-Like Proteins

(2012) Annemarthe G. van der Veen et al.   Annual Review of Biochemistry

Post-translational modifications induce significant yet not extreme changes to protein structure

(2012) Fuxiao Xin et al.   BIOINFORMATICS

Palmitoylation of virus proteins

(2012) Michael Veit   BIOLOGY OF THE CELL

N-Myristoylation and Ca2+Binding of Calcineurin B Homologous Protein CHP3 Are Required to Enhance Na+/H+Exchanger NHE1 Half-life and Activity at the Plasma Membrane

(2012) Hans C. Zaun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Double-stranded RNA-activated Protein Kinase (PKR) by Interferon-stimulated Gene 15 (ISG15) Modification Down-regulates Protein Translation

(2012) Fumihiko Okumura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New PARP Gene with an Anti-Alphavirus Function

(2012) S. Atasheva et al.   JOURNAL OF VIROLOGY

Poly(ADP-Ribose) Polymerase 1 Promotes Transcriptional Repression of Integrated Retroviruses

(2012) M. T. D. Bueno et al.   JOURNAL OF VIROLOGY

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rotavirus Viroplasm Fusion and Perinuclear Localization Are Dynamic Processes Requiring Stabilized Microtubules

(2012) Catherine Eichwald et al.   PLoS One

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

(2012) Sebastian Aguirre et al.   PLoS Pathogens

Acetylation is indispensable for p53 antiviral activity

(2011) Cesar Muñoz-Fontela et al.   CELL CYCLE

Impairment of Human Immunodeficiency Virus Type-1 Integrase SUMOylation Correlates with an Early Replication Defect

(2011) Alessia Zamborlini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sumoylation-promoted Enterovirus 71 3C Degradation Correlates with a Reduction in Viral Replication and Cell Apoptosis

(2011) Shu-Chuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SUMOylation of Matrix Protein M1 Modulates the Assembly and Morphogenesis of Influenza A Virus

(2011) C.-Y. Wu et al.   JOURNAL OF VIROLOGY

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

(2011) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement-Mediated Neutralization of Dengue Virus Requires Mannose-Binding Lectin

(2011) P. Avirutnan et al.   mBio

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)

(2011) Naoki Sakane et al.   PLoS Pathogens

Identification and characterization of protein glycosylation using specific endo- and exoglycosidases

(2011) Paula E. Magnelli et al.   Jove-Journal of Visualized Experiments

Ubiquitination and deubiquitination of NP protein regulates influenza A virus RNA replication

(2010) Tsai-Ling Liao et al.   EMBO JOURNAL

Palmitoylome profiling reveals S-palmitoylation–dependent antiviral activity of IFITM3

(2010) Jacob S Yount et al.   Nature Chemical Biology

ISG15 conjugation system targets the viral NS1 protein in influenza A virus-infected cells

(2010) C. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

(2010) Michael O. Hottiger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Palmitoylation of SARS-CoV S protein is necessary for partitioning into detergent-resistant membranes and cell–cell fusion but not interaction with M protein

(2010) Corrin E. McBride et al.   VIROLOGY

SUMOylation of RIG-I positively regulates the type I interferon signaling

(2010) Zhiqiang Mi et al.   Protein & Cell

Ubiquitylation on Canonical and Non-canonical Sites Targets the Transcription Factor Neurogenin for Ubiquitin-mediated Proteolysis

(2009) Jonathan M. D. Vosper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitoylation of Interferon-α (IFN-α) Receptor Subunit IFNAR1 Is Required for the Activation of Stat1 and Stat2 by IFN-α

(2009) Julie Claudinon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dengue Virus NS5 Inhibits Interferon‐α Signaling by Blocking Signal Transducer and Activator of Transcription 2 Phosphorylation

(2009) Michela Mazzon et al.   JOURNAL OF INFECTIOUS DISEASES

Palmitoylation of the Influenza A Virus M2 Protein Is Not Required for Virus Replication In Vitro but Contributes to Virus Virulence

(2009) M. L. Grantham et al.   JOURNAL OF VIROLOGY

Ebolavirus Glycoprotein GP Masks both Its Own Epitopes and the Presence of Cellular Surface Proteins

(2009) O. Reynard et al.   JOURNAL OF VIROLOGY

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

(2009) H. Malet et al.   JOURNAL OF VIROLOGY

Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF- B Signaling

(2009) M. Frieman et al.   JOURNAL OF VIROLOGY

Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

(2009) Tsung-Hsien Chang et al.   PLoS Pathogens

The nucleocapsid protein of SARS-associated coronavirus inhibits B23 phosphorylation

(2008) Yingchun Zeng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nef and TNFα are Coplayers that Favor HIV-1 Replication in Monocytic Cells and Primary Macrophages

(2008) Georges Herbein et al.   CURRENT HIV RESEARCH

Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein

(2008) Julie A. Kerns et al.   PLoS Genetics

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity

(2008) A. Okumura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR

(2008) Rachel Van Duyne et al.   Retrovirology