Activation of Double-stranded RNA-activated Protein Kinase (PKR) by Interferon-stimulated Gene 15 (ISG15) Modification Down-regulates Protein Translation

Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15

(2012) Young Joo Jeon et al.   JOURNAL OF CLINICAL INVESTIGATION

HERC6 Is the Main E3 Ligase for Global ISG15 Conjugation in Mouse Cells

(2012) Diede Oudshoorn et al.   PLoS One

mHERC6 is the essential ISG15 E3 ligase in the murine system

(2011) Lars Ketscher et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRIM8 regulates Nanog via Hsp90β-mediated nuclear translocation of STAT3 in embryonic stem cells

(2011) Fumihiko Okumura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The ISG15/USP18 ubiquitin-like pathway (ISGylation system) in Hepatitis C Virus infection and resistance to interferon therapy

(2011) Limin Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Short RNA Duplexes Elicit RIG-I-Mediated Apoptosis in a Cell Type- and Length-Dependent Manner

(2011) O. Ishibashi et al.   Science Signaling

Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis

(2010) Takahisa Nakamura et al.   CELL

Protein Kinase R Contributes to Immunity against Specific Viruses by Regulating Interferon mRNA Integrity

(2010) Oliver Schulz et al.   Cell Host & Microbe

Interferon-Stimulated Gene 15 and the Protein ISGylation System

(2010) Dongxian Zhang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Positive Regulation of Interferon Regulatory Factor 3 Activation by Herc5 via ISG15 Modification

(2010) H. X. Shi et al.   MOLECULAR AND CELLULAR BIOLOGY

ISG15 conjugation system targets the viral NS1 protein in influenza A virus-infected cells

(2010) C. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway

(2009) Young Joo Jeon et al.   EMBO REPORTS

Nitrosylation of ISG15 Prevents the Disulfide Bond-mediated Dimerization of ISG15 and Contributes to Effective ISGylation

(2008) Fumihiko Okumura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY