The Gut-Brain Axis in Autism Spectrum Disorder: A Focus on the Metalloproteases ADAM10 and ADAM17
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Gut-Brain Axis in Autism Spectrum Disorder: A Focus on the Metalloproteases ADAM10 and ADAM17
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 1, Pages 118
Publisher
MDPI AG
Online
2020-12-24
DOI
10.3390/ijms22010118
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
- (2020) Mahmoud Gheblawi et al. CIRCULATION RESEARCH
- Altered Caecal Neuroimmune Interactions in the Neuroligin-3R451C Mouse Model of Autism
- (2020) Samiha Sayed Sharna et al. Frontiers in Cellular Neuroscience
- The Promising Role of Probiotics in Managing the Altered Gut in Autism Spectrum Disorders
- (2020) Basma Abdellatif et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A shedding soluble form of interleukin-17 receptor D exacerbates collagen-induced arthritis through facilitating TNF-α-dependent receptor clustering
- (2020) Sihan Liu et al. Cellular & Molecular Immunology
- Role of the Gut Microbiota in the Pathophysiology of Autism Spectrum Disorder: Clinical and Preclinical Evidence
- (2020) Léa Roussin et al. Microorganisms
- Loss of RHBDF2 results in an early‐onset spontaneous murine colitis
- (2019) Ramasatyaveni Geesala et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Neuromodulation of autism spectrum disorders using vagal nerve stimulation
- (2019) Alje van Hoorn et al. JOURNAL OF CLINICAL NEUROSCIENCE
- NrCAM is a marker for substrate‐selective activation of ADAM10 in Alzheimer's disease
- (2019) Tobias Brummer et al. EMBO Molecular Medicine
- Colonic dilation and altered ex vivo gastrointestinal motility in the neuroligin‐3 knockout mouse
- (2019) Anita J. L. Leembruggen et al. Autism Research
- Gastrointestinal dysfunction in patients and mice expressing the autism‐associated r451c mutation in neuroligin‐3
- (2019) Suzanne Hosie et al. Autism Research
- The influence of neuroinflammation in Autism Spectrum Disorder
- (2019) Samantha M. Matta et al. BRAIN BEHAVIOR AND IMMUNITY
- The metalloprotease ADAM17 in inflammation and cancer
- (2019) Stefan Düsterhöft et al. PATHOLOGY RESEARCH AND PRACTICE
- Notch Signaling in Mammalian Intestinal Stem Cells: Determining Cell Fate and Maintaining Homeostasis
- (2019) Shao-Jie Liang et al. Current Stem Cell Research & Therapy
- Clostridium perfringens Delta-Toxin Damages the Mouse Small Intestine
- (2019) Soshi Seike et al. Toxins
- The Relationship Among Gastrointestinal Symptoms, Problem Behaviors, and Internalizing Symptoms in Children and Adolescents With Autism Spectrum Disorder
- (2019) Bradley J. Ferguson et al. Frontiers in Psychiatry
- Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
- (2019) Gil Sharon et al. CELL
- Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder
- (2019) Khushmol K. Dhaliwal et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters
- (2019) Justin H. Trotter et al. JOURNAL OF CELL BIOLOGY
- Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling
- (2019) Georgia Gunner et al. NATURE NEUROSCIENCE
- Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota
- (2019) Dae-Wook Kang et al. Scientific Reports
- A molecular biomarker for prediction of clinical outcome in children with ASD, constipation, and intestinal inflammation
- (2019) Stephen J. Walker et al. Scientific Reports
- Probiotic Therapy for Treating Behavioral and Gastrointestinal Symptoms in Autism Spectrum Disorder: A Systematic Review of Clinical Trials
- (2019) Jun Liu et al. Current Medical Science
- T lymphocytes and cytotoxic astrocyte blebs correlate across autism brains
- (2019) Marcello M. DiStasio et al. ANNALS OF NEUROLOGY
- miR-23b Negatively Regulates Sepsis-Induced Inflammatory Responses by Targeting ADAM10 in Human THP-1 Monocytes
- (2019) Wenying Zhang et al. MEDIATORS OF INFLAMMATION
- Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions
- (2019) Maria Vittoria Ristori et al. Nutrients
- Maternal and early postnatal immune activation produce sex-specific effects on autism-like behaviors and neuroimmune function in mice
- (2019) William A. Carlezon et al. Scientific Reports
- Incidence of Clostridium perfringens and its toxin genes in the gut of children with autism spectrum disorder
- (2019) Maryam K. Alshammari et al. ANAEROBE
- Microbiota and gut-brain axis dysfunction in autism spectrum disorder: Evidence for functional gastrointestinal disorders
- (2019) I. Lasheras et al. Asian Journal of Psychiatry
- Toxin profile of fecal Clostridium perfringens strains isolated from children with autism spectrum disorders
- (2018) Bartłomiej Góra et al. ANAEROBE
- Delta-toxin from Clostridium perfringens perturbs intestinal epithelial barrier function in Caco-2 cell monolayers
- (2018) Soshi Seike et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15
- (2018) Lisa Seipold et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Temporal Regulation of Dendritic Spines Through NrCAM-Semaphorin3F Receptor Signaling in Developing Cortical Pyramidal Neurons
- (2018) Vishwa Mohan et al. CEREBRAL CORTEX
- Role of the immune system in autism spectrum disorders (ASD)
- (2018) Heidi Ormstad et al. CNS & Neurological Disorders-Drug Targets
- Non‐cell‐autonomous function of DR6 in Schwann cell proliferation
- (2018) Alessio Colombo et al. EMBO JOURNAL
- Resveratrol attenuates pro-inflammatory cytokines and activation of JAK1-STAT3 in BTBR T + Itpr3 tf /J autistic mice
- (2018) Sheikh F. Ahmad et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity
- (2018) Fabia Filipello et al. IMMUNITY
- Impact of Auditory Integrative Training on Transforming Growth Factor-β1 and Its Effect on Behavioral and Social Emotions in Children with Autism Spectrum Disorder
- (2018) Laila Al-Ayadhi et al. MEDICAL PRINCIPLES AND PRACTICE
- In Search of Selectivity in Inhibition of ADAM10
- (2018) Kiran V. Mahasenan et al. ACS Medicinal Chemistry Letters
- Glutamate and GABA in autism spectrum disorder—a translational magnetic resonance spectroscopy study in man and rodent models
- (2018) Jamie Horder et al. Translational Psychiatry
- The Perturbance of Microbiome and Gut-Brain Axis in Autism Spectrum Disorders
- (2018) Greta Fowlie et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autism spectrum disorder
- (2018) Catherine Lord et al. LANCET
- A prebiotic intervention study in children with autism spectrum disorders (ASDs)
- (2018) Roberta Grimaldi et al. Microbiome
- Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder
- (2018) Martina Sgritta et al. NEURON
- Enteric infection coupled with chronic Notch pathway inhibition alters colonic mucus composition leading to dysbiosis, barrier disruption and colitis
- (2018) Ishfaq Ahmed et al. PLoS One
- Role of Microglia TLRs in Neurodegeneration
- (2018) Bernd L. Fiebich et al. Frontiers in Cellular Neuroscience
- Synaptopathology Involved in Autism Spectrum Disorder
- (2018) Shiqi Guang et al. Frontiers in Cellular Neuroscience
- Gut Microbiota Features in Young Children With Autism Spectrum Disorders
- (2018) Lorena Coretti et al. Frontiers in Microbiology
- ADAM10 as a therapeutic target for brain diseases: from developmental disorders to Alzheimer’s disease
- (2017) Elena Marcello et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- The Heritability of Autism Spectrum Disorder
- (2017) Sven Sandin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Soluble TREM2 induces inflammatory responses and enhances microglial survival
- (2017) Li Zhong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation
- (2017) Marcia L. Moss et al. MEDIATORS OF INFLAMMATION
- Early brain development in infants at high risk for autism spectrum disorder
- (2017) Heather Cody Hazlett et al. NATURE
- Interactions between the microbiota, immune and nervous systems in health and disease
- (2017) Thomas C Fung et al. NATURE NEUROSCIENCE
- ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157
- (2017) Dominik Feuerbach et al. NEUROSCIENCE LETTERS
- Is functional brain connectivity atypical in autism? A systematic review of EEG and MEG studies
- (2017) Christian O’Reilly et al. PLoS One
- Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest
- (2017) Isabel Espinosa-Medina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice
- (2017) Mauricio D. Dorfman et al. Nature Communications
- The Immune System, Cytokines, and Biomarkers in Autism Spectrum Disorder
- (2017) Anne Masi et al. Neuroscience Bulletin
- Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain
- (2017) Kendra L. Puig et al. Scientific Reports
- Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation
- (2017) Steffen Riethmueller et al. PLOS BIOLOGY
- Abundance and Significance of Neuroligin-1 and Neurexin II in the Enteric Nervous System of Embryonic Rats
- (2017) Dongming Wang et al. Biomed Research International
- Transcutaneous Vagus Nerve Stimulation: A Promising Method for Treatment of Autism Spectrum Disorders
- (2017) Yu Jin et al. Frontiers in Neuroscience
- Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism
- (2017) Anna V. Golubeva et al. EBioMedicine
- Inhibition of IL-6 trans-signaling in the brain increases sociability in the BTBR mouse model of autism
- (2016) Hongen Wei et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring
- (2016) Shelly A. Buffington et al. CELL
- Hypertension-Linked Pathophysiological Alterations in the GutNovelty and Significance
- (2016) Monica M. Santisteban et al. CIRCULATION RESEARCH
- Autism spectrum disorder phenotype and intellectual disability in females with epilepsy and PCDH-19 mutations
- (2016) Delphine Breuillard et al. EPILEPSY & BEHAVIOR
- TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage
- (2016) Roslyn A. Taylor et al. JOURNAL OF CLINICAL INVESTIGATION
- Targeting ADAM17 in leukocytes increases neutrophil recruitment and reduces bacterial spread during polymicrobial sepsis
- (2016) Hemant K Mishra et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes
- (2016) Sinead A. O’Sullivan et al. Journal of Neuroinflammation
- The Role of the Immune System in Autism Spectrum Disorder
- (2016) Amory Meltzer et al. NEUROPSYCHOPHARMACOLOGY
- Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids
- (2016) Alexandra L. Matthews et al. PLATELETS
- The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
- (2016) G. B. Choi et al. SCIENCE
- Can probiotics benefit children with autism spectrum disorders?
- (2016) Fernando Navarro et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets
- (2016) Shinji Hirata et al. Stem Cells Translational Medicine
- Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function
- (2016) Peer-Hendrik Kuhn et al. eLife
- Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders
- (2016) Maria Fiorentino et al. Molecular Autism
- Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue
- (2016) Balmiki Ray et al. Scientific Reports
- Shedding of neurexin 3β ectodomain by ADAM10 releases a soluble fragment that affects the development of newborn neurons
- (2016) Erika Borcel et al. Scientific Reports
- Slow intestinal transit contributes to elevate urinaryp-cresol level in Italian autistic children
- (2015) Stefano Gabriele et al. Autism Research
- Genetic Mapping in Mice Reveals the Involvement of Pcdh9 in Long-Term Social and Object Recognition and Sensorimotor Development
- (2015) Hilgo Bruining et al. BIOLOGICAL PSYCHIATRY
- The blood-brain barrier in neuroimmunology: Tales of separation and assimilation
- (2015) W.A. Banks BRAIN BEHAVIOR AND IMMUNITY
- In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes
- (2015) Pietra Candela et al. BRAIN RESEARCH
- Control of Brain Development, Function, and Behavior by the Microbiome
- (2015) Timothy R. Sampson et al. Cell Host & Microbe
- TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization
- (2015) Stéphanie Jouannet et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The Distinct Role of ADAM17 in APP Proteolysis and Microglial Activation Related to Alzheimer’s Disease
- (2015) Meng Qian et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Dynamics of ADAM17-Mediated Shedding of ACE2 Applied to Pancreatic Islets of Maledb/dbMice
- (2015) Kim Brint Pedersen et al. ENDOCRINOLOGY
- Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells
- (2015) Christopher S. Reigstad et al. FASEB JOURNAL
- Whole Exome Sequencing in Females with Autism Implicates Novel and Candidate Genes
- (2015) Merlin Butler et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions
- (2015) Peter J. Noy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ACE2 and Microbiota
- (2015) Colleen T. Cole-Jeffrey et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier
- (2015) Steffen E. Storck et al. JOURNAL OF CLINICAL INVESTIGATION
- ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses
- (2015) Isabell Yan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- ADAM10 and BACE1 are localized to synaptic vesicles
- (2015) Jolanta L. Lundgren et al. JOURNAL OF NEUROCHEMISTRY
- Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan
- (2015) Christine Ecker et al. LANCET NEUROLOGY
- Gene hunting in autism spectrum disorder: on the path to precision medicine
- (2015) Daniel H Geschwind et al. LANCET NEUROLOGY
- The role of TIMPs in regulation of extracellular matrix proteolysis
- (2015) Valerie Arpino et al. MATRIX BIOLOGY
- Host microbiota constantly control maturation and function of microglia in the CNS
- (2015) Daniel Erny et al. NATURE NEUROSCIENCE
- Cell type– and brain region–resolved mouse brain proteome
- (2015) Kirti Sharma et al. NATURE NEUROSCIENCE
- Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome
- (2015) Emanuela Pasciuto et al. NEURON
- Protection of TGF-β1 against Neuroinflammation and Neurodegeneration in Aβ1–42-Induced Alzheimer’s Disease Model Rats
- (2015) Jia-Hui Chen et al. PLoS One
- Amyloid Precursor Protein Mediated Changes in Intestinal Epithelial Phenotype In Vitro
- (2015) Kendra L. Puig et al. PLoS One
- Role of the Microbiota in Immunity and Inflammation
- (2014) Yasmine Belkaid et al. CELL
- Interleukin-6 and its receptors: A highly regulated and dynamic system
- (2014) Janina Wolf et al. CYTOKINE
- ADAM10 Regulates Notch Function in Intestinal Stem Cells of Mice
- (2014) Yu-Hwai Tsai et al. GASTROENTEROLOGY
- Neural Cell Adhesion Molecule NrCAM Regulates Semaphorin 3F-Induced Dendritic Spine Remodeling
- (2014) G. P. Demyanenko et al. JOURNAL OF NEUROSCIENCE
- Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis
- (2014) A Masi et al. MOLECULAR PSYCHIATRY
- Resveratrol prevents social deficits in animal model of autism induced by valproic acid
- (2014) Victorio Bambini-Junior et al. NEUROSCIENCE LETTERS
- Gastrointestinal Symptoms in Autism Spectrum Disorder: A Meta-analysis
- (2014) B. O. McElhanon et al. PEDIATRICS
- Genetic variants of Adam17 differentially regulate TGF signaling to modify vascular pathology in mice and humans
- (2014) K. Kawasaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered Peripheral and Central Inflammatory Responses in a Mouse Model of Autism
- (2013) Luciana Lucchina et al. Autism Research
- Altered gut microbiota and activity in a murine model of autism spectrum disorders
- (2013) Caroline G.M. de Theije et al. BRAIN BEHAVIOR AND IMMUNITY
- Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
- (2013) Elaine Y. Hsiao et al. CELL
- Lipopolysaccharide Activates Toll-like Receptor 4 (TLR4)-mediated NF-κB Signaling Pathway and Proinflammatory Response in Human Pericytes
- (2013) Irene Guijarro-Muñoz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia
- (2013) Linli Yao et al. Journal of Neuroinflammation
- Postnatal Disruption of the Disintegrin/Metalloproteinase ADAM10 in Brain Causes Epileptic Seizures, Learning Deficits, Altered Spine Morphology, and Defective Synaptic Functions
- (2013) J. Prox et al. JOURNAL OF NEUROSCIENCE
- Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
- (2013) Yukihiro Furusawa et al. NATURE
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling
- (2013) Csaba Földy et al. NEURON
- iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding
- (2013) T. Maretzky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis
- (2013) P. M. Smith et al. SCIENCE
- Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway
- (2013) Debomoy K. Lahiri et al. Frontiers in Cellular Neuroscience
- Neurexins
- (2013) Carsten Reissner et al. GENOME BIOLOGY
- Amniotic Fluid MMP-9 and Neurotrophins in Autism Spectrum Disorders: An Exploratory Study
- (2012) Morsi W. Abdallah et al. Autism Research
- Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors
- (2012) Hongen Wei et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses
- (2012) Dilja D Krueger et al. CURRENT OPINION IN NEUROBIOLOGY
- Elevated Fecal Short Chain Fatty Acid and Ammonia Concentrations in Children with Autism Spectrum Disorder
- (2012) Lv Wang et al. DIGESTIVE DISEASES AND SCIENCES
- Butyrate Enhances Intestinal Epithelial Barrier Function via Up-Regulation of Tight Junction Protein Claudin-1 Transcription
- (2012) Hong-Bo Wang et al. DIGESTIVE DISEASES AND SCIENCES
- Emerging new roles of Th17 cells
- (2012) Vijay K. Kuchroo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6
- (2012) Stefan Rose-John International Journal of Biological Sciences
- The TspanC8 Subgroup of Tetraspanins Interacts with A Disintegrin and Metalloprotease 10 (ADAM10) and Regulates Its Maturation and Cell Surface Expression
- (2012) Elizabeth J. Haining et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The interplay between the intestinal microbiota and the brain
- (2012) Stephen M. Collins et al. NATURE REVIEWS MICROBIOLOGY
- Neuroinflammation: A Common Pathway in CNS Diseases as Mediated at the Blood-Brain Barrier
- (2012) Michelle A. Erickson et al. NEUROIMMUNOMODULATION
- Transsynaptic Signaling by Activity-Dependent Cleavage of Neuroligin-1
- (2012) Rui T. Peixoto et al. NEURON
- Activity-Dependent Proteolytic Cleavage of Neuroligin-1
- (2012) Kunimichi Suzuki et al. NEURON
- Urinary p-cresol in autism spectrum disorder
- (2012) Antonio M. Persico et al. NEUROTOXICOLOGY AND TERATOLOGY
- Tumor Necrosis Factor Signaling Requires iRhom2 to Promote Trafficking and Activation of TACE
- (2012) C. Adrain et al. SCIENCE
- Brain abnormalities in a Neuroligin3 R451C knockin mouse model associated with autism
- (2011) Jacob Ellegood et al. Autism Research
- The pro- and anti-inflammatory properties of the cytokine interleukin-6
- (2011) Jürgen Scheller et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Urinaryp-cresol is elevated in small children with severe autism spectrum disorder
- (2011) Laura Altieri et al. BIOMARKERS
- Early and adult hippocampal TGF-β1 overexpression have opposite effects on behavior
- (2011) Amaicha Mara Depino et al. BRAIN BEHAVIOR AND IMMUNITY
- Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding
- (2011) Christoph Garbers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid Precursor Protein Expression Modulates Intestine Immune Phenotype
- (2011) Kendra L. Puig et al. Journal of Neuroimmune Pharmacology
- CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity
- (2011) J. T. Rogers et al. JOURNAL OF NEUROSCIENCE
- A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures
- (2011) D A Rossignol et al. MOLECULAR PSYCHIATRY
- Downregulating DR6 to drive remyelination
- (2011) Brian Popko NATURE MEDICINE
- Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination
- (2011) Sha Mi et al. NATURE MEDICINE
- Increased Secreted Amyloid Precursor Protein-α (sAPPα) in Severe Autism: Proposal of a Specific, Anabolic Pathway and Putative Biomarker
- (2011) Balmiki Ray et al. PLoS One
- Reversal of Fragile X Phenotypes by Manipulation of AβPP/Aβ Levels in Fmr1KO Mice
- (2011) Cara J. Westmark et al. PLoS One
- Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
- (2011) R. C. Paolicelli et al. SCIENCE
- ADAM17: a molecular switch to control inflammation and tissue regeneration
- (2011) Jürgen Scheller et al. TRENDS IN IMMUNOLOGY
- Deciphering the role of Th17 cells in human disease
- (2011) Cailin Moira Wilke et al. TRENDS IN IMMUNOLOGY
- Death receptor signalling in central nervous system inflammation and demyelination
- (2011) Conor Mc Guire et al. TRENDS IN NEUROSCIENCES
- Lymphotoxin-αβ heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis
- (2010) Judy Young et al. CYTOKINE
- ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons
- (2010) Peer-Hendrik Kuhn et al. EMBO JOURNAL
- The soluble Interleukin 6 receptor: Generation and role in inflammation and cancer
- (2010) Athena Chalaris et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Notch-1 Signaling Regulates Intestinal Epithelial Barrier Function, Through Interaction With CD4+ T Cells, in Mice and Humans
- (2010) Stephanie Dahan et al. GASTROENTEROLOGY
- Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases
- (2010) Nathalie Bot et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice
- (2010) Athena Chalaris et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?
- (2010) S. Rivera et al. JOURNAL OF NEUROSCIENCE
- Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior
- (2010) J. Blundell et al. JOURNAL OF NEUROSCIENCE
- Alterations of the Intestinal Barrier in Patients With Autism Spectrum Disorders and in Their First-degree Relatives
- (2010) Laura de Magistris et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Improved Synthesis of ADAM10 Inhibitor GI254023X
- (2010) Nicole Hoettecke et al. Neurodegenerative Diseases
- Low-grade endotoxemia in patients with severe autism
- (2010) Enzo Emanuele et al. NEUROSCIENCE LETTERS
- ADAM17 (TACE) regulates TGFβ signaling through the cleavage of vasorin
- (2010) J Malapeira et al. ONCOGENE
- The metzincins - Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc-peptidases
- (2010) Walter Stöcker et al. PROTEIN SCIENCE
- Impaired sociability and cognitive function in Nrcam-null mice
- (2009) Sheryl S. Moy et al. BEHAVIOURAL BRAIN RESEARCH
- Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models
- (2009) Miriam Fanjul-Fernández et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
- (2009) Jeffrey J. Hutsler et al. BRAIN RESEARCH
- Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts
- (2009) Renata Mężyk-Kopeć et al. CYTOKINE
- Clostridial toxins
- (2009) Michel R Popoff et al. Future Microbiology
- Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit
- (2009) K. Radyushkin et al. GENES BRAIN AND BEHAVIOR
- A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia
- (2009) Christine L. Hsieh et al. JOURNAL OF NEUROCHEMISTRY
- Elevated immune response in the brain of autistic patients
- (2009) Xiaohong Li et al. JOURNAL OF NEUROIMMUNOLOGY
- Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers
- (2009) Luying Peng et al. JOURNAL OF NUTRITION
- TACE-Mediated Ectodomain Shedding of the Type I TGF-β Receptor Downregulates TGF-β Signaling
- (2009) Cheng Liu et al. MOLECULAR CELL
- Autism genome-wide copy number variation reveals ubiquitin and neuronal genes
- (2009) Joseph T. Glessner et al. NATURE
- APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
- (2009) Anatoly Nikolaev et al. NATURE
- Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
- (2009) W. R. Wikoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Variation of Chromosomes in Autism Spectrum Disorder
- (2008) Christian R. Marshall et al. AMERICAN JOURNAL OF HUMAN GENETICS
- ADAM10 Regulates Endothelial Permeability and T-Cell Transmigration by Proteolysis of Vascular Endothelial Cadherin
- (2008) Beate Schulz et al. CIRCULATION RESEARCH
- Association of the neuronal cell adhesion molecule (NRCAM) gene variants with autism
- (2008) Tetsuya Marui et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Amyloid Precursor Protein Trafficking, Processing, and Function
- (2008) Gopal Thinakaran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ADAM10-Mediated E-Cadherin Release Is Regulated by Proinflammatory Cytokines and Modulates Keratinocyte Cohesion in Eczematous Dermatitis
- (2008) Thorsten Maretzky et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Decreased transforming growth factor beta1 in autism: A potential link between immune dysregulation and impairment in clinical behavioral outcomes
- (2008) P ASHWOOD et al. JOURNAL OF NEUROIMMUNOLOGY
- The ADAM metalloproteinases
- (2008) D EDWARDS et al. MOLECULAR ASPECTS OF MEDICINE
- Abnormal axonal guidance and brain anatomy in mouse mutants for the cell recognition molecules close homolog of L1 and NgCAM-related cell adhesion molecule
- (2008) A. Heyden et al. NEUROSCIENCE
- Identifying Autism Loci and Genes by Tracing Recent Shared Ancestry
- (2008) E. M. Morrow et al. SCIENCE
- The “A Disintegrin And Metalloprotease” (ADAM) family of sheddases: Physiological and cellular functions
- (2008) Karina Reiss et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started