Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes

Synergistic induction of CXCL10 by interferon-gamma and lymphotoxin-alpha in astrocytes: Possible role in cerebral malaria

(2016) Supun M. Bakmiwewa et al.   CYTOKINE

The opioid antagonist, β-funaltrexamine, inhibits NF-κB signaling and chemokine expression in human astrocytes and in mice

(2015) Randall L. Davis et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling

(2015) C. O'Sullivan et al.   JOURNAL OF CELL SCIENCE

Caspase-9 activation and Apaf-1 cleavage by MMP-3

(2014) Eun-Mee Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LPS and IL-1 differentially activate mouse and human astrocytes: Role of CD14

(2014) Leonid Tarassishin et al.   GLIA

The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes

(2014) Gaelle Elain et al.   GLIA

EBI2 regulates intracellular signaling and migration in human astrocyte

(2014) Aleksandra Rutkowska et al.   GLIA

Essential Involvement of CX3CR1-Mediated Signals in the Bactericidal Host Defense during Septic Peritonitis

(2014) Y. Ishida et al.   JOURNAL OF IMMUNOLOGY

Upregulation of APP, ADAM10 and ADAM17 in the Denervated Mouse Dentate Gyrus

(2014) Domenico Del Turco et al.   PLoS One

Role of ADAM-17, p38 MAPK, Cathepsins, and the Proteasome Pathway in the Synthesis and Shedding of Fractalkine/CX3CL1 in Rheumatoid Arthritis

(2013) Brian A. Jones et al.   ARTHRITIS AND RHEUMATISM

Pathway specific modulation of S1P1 receptor signalling in rat and human astrocytes

(2013) Luke M Healy et al.   BRITISH JOURNAL OF PHARMACOLOGY

ADAM10 as a Biomarker for Alzheimer’s Disease: A Study with Brazilian Elderly

(2013) Patricia Regina Manzine et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Shedding of Discoidin Domain Receptor 1 by Membrane-type Matrix Metalloproteinases

(2013) Hsueh-Liang Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of IRS-1 Interaction With ADAM10 in the Regulation of Neurite Extension

(2013) Jin Ying Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CX3CL1 protects neurons against excitotoxicity enhancing GLT-1 activity on astrocytes

(2013) Myriam Catalano et al.   JOURNAL OF NEUROIMMUNOLOGY

Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1

(2013) Yutaka Koyama et al.   Journal of Neuroinflammation

Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells

(2013) Hidemi Yoshida et al.   NEUROSCIENCE RESEARCH

Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage

(2013) G. K. Sheridan et al.   Open Biology

C/EBPβ regulates multiple IL-1β-induced human astrocyte inflammatory genes

(2012) Jerel Fields et al.   Journal of Neuroinflammation

Deficiency of the Microglial Receptor CX3CR1 Impairs Postnatal Functional Development of Thalamocortical Synapses in the Barrel Cortex

(2012) M. Hoshiko et al.   JOURNAL OF NEUROSCIENCE

siRNA knockdown of ADAM-10, but not ADAM-17, significantly reduces fractalkine shedding following pro-inflammatory cytokine treatment in a human adult brain endothelial cell line

(2012) Louise A. Hurst et al.   NEUROSCIENCE LETTERS

HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms

(2011) Manmeet K Mamik et al.   Journal of Neuroinflammation

CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease

(2011) Mibel M Pabon et al.   Journal of Neuroinflammation

CX3CL1 Is Neuroprotective in Permanent Focal Cerebral Ischemia in Rodents

(2011) R. Cipriani et al.   JOURNAL OF NEUROSCIENCE

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Interactions between Chemokines

(2010) Anna Cook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hemin inhibits NO production by IL-1β-stimulated human astrocytes through induction of heme oxygenase-1 and reduction of p38 MAPK activation

(2010) Wen S Sheng et al.   Journal of Neuroinflammation

Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: Results of two randomized, double-blind, placebo-controlled clinical studies

(2009) Nemanja Damjanov et al.   ARTHRITIS AND RHEUMATISM

Albumin activates astrocytes and microglia through mitogen-activated protein kinase pathways

(2009) Hantamalala Ralay Ranaivo et al.   BRAIN RESEARCH

CX3CL1/fractalkine shedding by human hepatic stellate cells: contribution to chronic inflammation in the liver

(2009) Katia Bourd-Boittin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Selective p38α Inhibitors Clinically Evaluated for the Treatment of Chronic Inflammatory Disorders

(2009) David M. Goldstein et al.   JOURNAL OF MEDICINAL CHEMISTRY

WIN55,212-2 Inhibits Production of CX3CL1 by Human Astrocytes: Involvement of p38 MAP Kinase

(2009) W. S. Sheng et al.   Journal of Neuroimmune Pharmacology

The Liberation of Fractalkine in the Dorsal Horn Requires Microglial Cathepsin S

(2009) A. K. Clark et al.   JOURNAL OF NEUROSCIENCE

HIV-1 Tat Co-Operates with IFN-γ and TNF-α to Increase CXCL10 in Human Astrocytes

(2009) Rachel Williams et al.   PLoS One

Glia in pathological pain: A role for fractalkine

(2008) E.D. Milligan et al.   JOURNAL OF NEUROIMMUNOLOGY