NLRP3 regulates alveolar bone loss in ligature‐induced periodontitis by promoting osteoclastic differentiation

The Anti-Periodontitis Action of Metformin via Targeting NLRP3 Inflammasome

(2020) Yongmei Tan et al.   ARCHIVES OF ORAL BIOLOGY

NLRP3 inflammasome mediates M1 macrophage polarization and IL‐1β production in inflammatory root resorption

(2020) Jie Zhang et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Advances in the molecular mechanisms of NLRP3 inflammasome activators and inactivators

(2020) Dongling Liu et al.   BIOCHEMICAL PHARMACOLOGY

Effects of Sulfonylureas on Periodontopathic Bacteria-Induced Inflammation

(2020) Y. Kawahara et al.   JOURNAL OF DENTAL RESEARCH

Oxidative stress induced pyroptosis leads to osteogenic dysfunction of MG63 cells

(2020) Shanshan Liu et al.   JOURNAL OF MOLECULAR HISTOLOGY

Effect of VEGFC on lymph flow and inflammation‐induced alveolar bone loss

(2020) Hua Wang et al.   JOURNAL OF PATHOLOGY

Tripartite motif 31 alleviates IL-1ß secretion via promoting the ubiquitination of pyrin domain domains-containing protein 3 in human periodontal ligament fibroblasts

(2020) Xueying Wu et al.   Odontology

Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype

(2020) Baohua Hou et al.   Cell Death & Disease

Relevance of Caspase-1 and Nlrp3 Inflammasome on Inflammatory Bone Resorption in A Murine Model of Periodontitis

(2020) Fernanda R G. Rocha et al.   Scientific Reports

Wedelolactone facilitates Ser/Thr phosphorylation of NLRP3 dependent on PKA signalling to block inflammasome activation and pyroptosis

(2020) Hao Pan et al.   CELL PROLIFERATION

Targeting NLRP3 Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss

(2020) Y. Zang et al.   JOURNAL OF DENTAL RESEARCH

The NLRP3 inflammasome: Mechanism of action, role in disease and therapies

(2020) Li Wang et al.   MOLECULAR ASPECTS OF MEDICINE

Chronic Inflammation as a Link between Periodontitis and Carcinogenesis

(2019) Anilei Hoare et al.   MEDIATORS OF INFLAMMATION

Association Between Periodontitis and Cognitive Impairment in Adults: A Systematic Review

(2019) Priscila Cunha Nascimento et al.   Frontiers in Neurology

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Suppressive effects of dehydrocostus lactone on the toll-like receptor signaling pathways

(2019) Su Yeon Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination

(2019) Zebing Rao et al.   Frontiers in Immunology

Melatonin Suppresses Estrogen Deficiency-Induced Osteoporosis and Promotes Osteoblastogenesis by Inactivating the NLRP3 Inflammasome

(2018) Lijun Xu et al.   CALCIFIED TISSUE INTERNATIONAL

Overexpressed Sirt1 in MSCs Promotes Dentin Formation in Bmi1-Deficient Mice

(2018) H. Wang et al.   JOURNAL OF DENTAL RESEARCH

MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice

(2018) Agampodi Promoda Perera et al.   Scientific Reports

Mouse Cre Models for the Study of Bone Diseases

(2018) Sarah L. Dallas et al.   Current Osteoporosis Reports

LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF-κB/NLRP3 inflammasome pathway

(2018) Mengru Ma et al.   CELL PROLIFERATION

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

(2018) Richard Gordon et al.   Science Translational Medicine

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

(2017) Hua Jiang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-1β Induces Pathologically Activated Osteoclasts Bearing Extremely High Levels of Resorbing Activity: A Possible Pathological Subpopulation of Osteoclasts, Accompanied by Suppressed Expression of Kindlin-3 and Talin-1

(2017) Takuma Shiratori et al.   JOURNAL OF IMMUNOLOGY

Porphyromonas gingivalis-Derived Lipopolysaccharide Combines Hypoxia to Induce Caspase-1 Activation in Periodontitis

(2017) Ran Cheng et al.   Frontiers in Cellular and Infection Microbiology

PTHrP Nuclear Localization and Carboxyl Terminus Sequences Modulate Dental and Mandibular Development in Part via the Action of p27

(2016) Wen Sun et al.   ENDOCRINOLOGY

Regulation of the NLRP3 inflammasome in Porphyromonas gingivalis-accelerated periodontal disease

(2016) Yohei Yamaguchi et al.   INFLAMMATION RESEARCH

NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms

(2015) Chao Qu et al.   FASEB JOURNAL

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

NLRP3 inflammasome and its inhibitors: a review

(2015) Bo-Zong Shao et al.   Frontiers in Pharmacology

Activation of NLRP3 and AIM2 Inflammasomes by Porphyromonas gingivalis Infection

(2013) Eunjoo Park et al.   INFECTION AND IMMUNITY

Cell therapy of periodontium: from animal to human?

(2013) Elena A. Trofin et al.   Frontiers in Physiology

Differential Expression of NLRP3 among Hematopoietic Cells

(2011) G. Guarda et al.   JOURNAL OF IMMUNOLOGY

Direct Inhibition of Human RANK+ Osteoclast Precursors Identifies a Homeostatic Function of IL-1 

(2010) B. Lee et al.   JOURNAL OF IMMUNOLOGY