Melatonin Suppresses Estrogen Deficiency-Induced Osteoporosis and Promotes Osteoblastogenesis by Inactivating the NLRP3 Inflammasome

Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome

(2017) Zhengwang Cao et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as an Anti-Inflammatory Agent Modulating Inflammasome Activation

(2017) Gaia Favero et al.   International Journal of Endocrinology

Knockdown of SIRT7 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the Wnt/β-catenin signaling pathway

(2017) Erman E M Chen et al.   Cell Death & Disease

Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation

(2017) Shenglong Cao et al.   Scientific Reports

Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance by suppressing NLRP3 inflammasome-mediated inflammation in type 2 diabetes rats

(2017) Xiaoya Sun et al.   Stem Cell Research & Therapy

Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis

(2017) Meng Qi et al.   Theranostics

SIRT6 promotes osteogenic differentiation of mesenchymal stem cells through BMP signaling

(2017) Ping Zhang et al.   Scientific Reports

Melatonin promotes osteoblast differentiation by regulating Osterix protein stability and expression

(2017) Younho Han et al.   Scientific Reports

NLRP3 inflammasome activation mediates estrogen deficiency-induced depression- and anxiety-like behavior and hippocampal inflammation in mice

(2016) Yongjun Xu et al.   BRAIN BEHAVIOR AND IMMUNITY

The myeloid heat shock transcription factor 1/β-catenin axis regulates NLR family, pyrin domain-containing 3 inflammasome activation in mouse liver ischemia/reperfusion injury

(2016) Shi Yue et al.   HEPATOLOGY

Melatonin attenuated adipogenesis through reduction of the CCAAT/enhancer binding protein beta by regulating the glycogen synthase 3 beta in human mesenchymal stem cells

(2016) Yun-Hee Rhee et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling

(2016) Yushu Dong et al.   JOURNAL OF PINEAL RESEARCH

Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome

(2016) Yong Zhang et al.   JOURNAL OF PINEAL RESEARCH

GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation

(2016) Weiqing Liu et al.   Nature Communications

Melatonin suppresses autophagy in type 2 diabetic osteoporosis

(2016) Wei-Lin Zhang et al.   Oncotarget

IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation

(2016) Mohd Nizam Mansoori et al.   Scientific Reports

The role of menopausal hormone therapy in the management of osteoporosis

(2015) T. J. de Villiers   CLIMACTERIC

Photoactivation of TAZ via Akt/GSK3β signaling pathway promotes osteogenic differentiation

(2015) Jie Feng et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Melatonin improves bone mineral density at the femoral neck in postmenopausal women with osteopenia: a randomized controlled trial

(2015) Anne Kristine Amstrup et al.   JOURNAL OF PINEAL RESEARCH

Melatonin promotes osteoblast differentiation and mineralization of MC3T3-E1 cells under hypoxic conditions through activation of PKD/p38 pathways

(2014) Jang-Ho Son et al.   JOURNAL OF PINEAL RESEARCH

Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis

(2014) Francisco Ortiz et al.   JOURNAL OF PINEAL RESEARCH

Tumor necrosis factor α suppresses the mesenchymal stem cell osteogenesis promoter miR-21 in estrogen deficiency-induced osteoporosis

(2012) Nan Yang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

(2012) Sheri L. Bonar et al.   PLoS One

Melatonin promotes osteoblastic differentiation through the BMP/ERK/Wnt signaling pathways

(2011) Ki-Ho Park et al.   JOURNAL OF PINEAL RESEARCH

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Melatonin: A pleiotropic molecule regulating inflammation

(2010) Flavia Radogna et al.   BIOCHEMICAL PHARMACOLOGY

Circulating mesenchymal stem cells with abnormal osteogenic differentiation in patients with osteoporosis

(2009) Luca Dalle Carbonare et al.   ARTHRITIS AND RHEUMATISM

Lipopolysaccharide up-regulates the expression of Fcα/μ receptor and promotes the binding of oxidized low-density lipoprotein and its IgM antibody complex to activated human macrophages

(2009) Xuyang Feng et al.   ATHEROSCLEROSIS

Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway: Inhibitors of the Wnt/β-Catenin Signaling Pathway as Novel Anticancer Drugs

(2009) Fumi Takahashi-Yanaga et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

A PLA/calcium phosphate degradable composite material for bone tissue engineering: an in vitro study

(2008) Montse Charles-Harris et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE