One ring to bring them all and in the darkness bind them: The trafficking of heme without deliverers

Interplay of Heme with Macrophages in Homeostasis and Inflammation

(2020) Pooja Pradhan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hc-hrg-2, a glutathione transferase gene, regulates heme homeostasis in the blood-feeding parasitic nematode Haemonchus contortus

(2020) Jing-Ru Zhou et al.   Parasites & Vectors

From Synthesis to Utilization: The Ins and Outs of Mitochondrial Heme

(2020) Samantha A. Swenson et al.   Cells

Machinery for fungal heme acquisition

(2020) Simon Labbé et al.   CURRENT GENETICS

Hereditary Ataxia: A Focus on Heme Metabolism and Fe-S Cluster Biogenesis

(2020) Deborah Chiabrando et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

GAPDH Delivers Heme to Soluble Guanylyl Cyclase

(2020) Yue Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial–nuclear heme trafficking in budding yeast is regulated by GTPases that control mitochondrial dynamics and ER contact sites

(2020) Osiris Martinez-Guzman et al.   JOURNAL OF CELL SCIENCE

The regulation and functions of DNA and RNA G-quadruplexes

(2020) Dhaval Varshney et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Physiological changes in the albumin-bound non-esterified free fatty acids critically influence heme/bilirubin binding properties of the protein: A comparative, in vitro, spectroscopic study using the endogenous biomolecules

(2020) Mahtab Amoorahim et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Human Ribosomal G-Quadruplexes Regulate Heme Bioavailability

(2020) Santi Mestre-Fos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

Regulation and Function of Mitochondria–Lysosome Membrane Contact Sites in Cellular Homeostasis

(2019) Yvette C. Wong et al.   TRENDS IN CELL BIOLOGY

The Expanding and Unexpected Functions of Mitochondria Contact Sites

(2019) Laura L. Lackner   TRENDS IN CELL BIOLOGY

VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation

(2019) Sandra Muñoz-Braceras et al.   Disease Models & Mechanisms

The human ABCB6 protein is the functional homologue of HMT-1 proteins mediating cadmium detoxification

(2019) Zsófia Rakvács et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Non-canonical DNA/RNA structures during Transcription-Coupled Double-Strand Break Repair: Roadblocks or Bona fide repair intermediates?

(2019) Nadine Puget et al.   DNA REPAIR

Mechanistic study of PpIX accumulation using the JFCR39 cell panel revealed a role for dynamin 2-mediated exocytosis

(2019) Yuya Kitajima et al.   Scientific Reports

Heme acquisition by Shu1 requires Nbr1 and proteins of the ESCRT complex in Schizosaccharomyces pombe

(2019) Thierry Mourer et al.   MOLECULAR MICROBIOLOGY

Hemozoin produced by mammals confers heme tolerance

(2019) Rini H Pek et al.   eLife

Membrane-Bound Meet Membraneless in Health and Disease

(2019) Chujun Zhang et al.   Cells

PGRMC2 is an intracellular haem chaperone critical for adipocyte function

(2019) Andrea Galmozzi et al.   NATURE

The ABCG2 multidrug transporter is a pump gated by a valve and an extracellular lid

(2019) Narakorn Khunweeraphong et al.   Nature Communications

Label-Free Imaging of Heme Dynamics in Living Organisms by Transient Absorption Microscopy

(2018) Andy Jing Chen et al.   ANALYTICAL CHEMISTRY

Glyceraldehyde 3-phosphate dehydrogenase is a chaperone that allocates labile heme in cells

(2018) Elizabeth A. Sweeny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

(2018) Yvette C. Wong et al.   NATURE

The multifaceted contributions of mitochondria to cellular metabolism

(2018) Jessica B. Spinelli et al.   NATURE CELL BIOLOGY

Endocytosis of Red Blood Cell Microparticles by Pulmonary Endothelial Cells is Mediated By Rab5

(2018) Young Kim et al.   SHOCK

Single organelle dynamics linked to 3D structure by correlative live-cell imaging and 3D electron microscopy

(2018) Job Fermie et al.   TRAFFIC

Mitochondria-associated membranes (MAMs) and pathologies

(2018) Paolo Pinton   Cell Death & Disease

Handling heme: The mechanisms underlying the movement of heme within and between cells

(2018) Rebecca K. Donegan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Super-Resolution Tracking of Mitochondrial Dynamics with An Iridium(III) Luminophore

(2018) Qixin Chen et al.   Small

Hrg1 promotes heme-iron recycling during hemolysis in the zebrafish kidney

(2018) Jianbing Zhang et al.   PLoS Genetics

Anaemia and malaria

(2018) Nicholas J. White   MALARIA JOURNAL

Zebrafish as a model system to delineate the role of heme and iron metabolism during erythropoiesis

(2018) Jianbing Zhang et al.   MOLECULAR GENETICS AND METABOLISM

Unraveling the Role of Heme in Neurodegeneration

(2018) Deborah Chiabrando et al.   Frontiers in Neuroscience

Mammalian mitophagy - from in vitro molecules to in vivo models

(2017) Catherine E. Rodger et al.   FEBS Journal

Iron transport proteins: Gateways of cellular and systemic iron homeostasis

(2017) Mitchell D. Knutson   JOURNAL OF BIOLOGICAL CHEMISTRY

Incredibly close—A newly identified peroxisome–ER contact site in humans

(2017) Maya Schuldiner et al.   JOURNAL OF CELL BIOLOGY

Quantitative Analysis of Human Red Blood Cell Proteome

(2017) Agata H. Bryk et al.   JOURNAL OF PROTEOME RESEARCH

Intracellular iron and heme trafficking and metabolism in developing erythroblasts

(2017) Martin D. Kafina et al.   Metallomics

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

(2017) Ayumu Sugiura et al.   NATURE

Inter-organ signalling by HRG-7 promotes systemic haem homeostasis

(2017) Jason Sinclair et al.   NATURE CELL BIOLOGY

The impact of replication stress on replication dynamics and DNA damage in vertebrate cells

(2017) Hervé Técher et al.   NATURE REVIEWS GENETICS

Crystal structures of Mmm1 and Mdm12–Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites

(2017) Hanbin Jeong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Do Mammalian Cells Really Need to Export and Import Heme?

(2017) Prem Ponka et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitochondrial dysfunction activates lysosomal-dependent mitophagy selectively in cancer cells

(2017) Thomas G. Biel et al.   Oncotarget

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart

(2017) Daniel Aston et al.   Scientific Reports

From Erythroblasts to Mature Red Blood Cells: Organelle Clearance in Mammals

(2017) Martina Moras et al.   Frontiers in Physiology

From the Cradle to the Grave: The Role of Macrophages in Erythropoiesis and Erythrophagocytosis

(2017) Thomas R. L. Klei et al.   Frontiers in Immunology

Heme Mobilization in Animals: A Metallolipid’s Journey

(2016) Amit R. Reddi et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase

(2016) Robert B. Piel et al.   BIOCHEMISTRY

VAP, a Versatile Access Point for the Endoplasmic Reticulum: Review and analysis of FFAT-like motifs in the VAPome

(2016) Sarah E. Murphy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The formation and function of ER-endosome membrane contact sites

(2016) Emily R. Eden   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

No peroxisome is an island — Peroxisome contact sites

(2016) Nadav Shai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Liquid–liquid phase separation in cellular signaling systems

(2016) P Andrew Chong et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites

(2016) Michal Eisenberg-Bord et al.   DEVELOPMENTAL CELL

Interaction of hemin with quadruplex DNA

(2016) Maryam Ghahremani Nasab et al.   JOURNAL OF BIOLOGICAL PHYSICS

Num1 anchors mitochondria to the plasma membrane via two domains with different lipid binding specificities

(2016) Holly A. Ping et al.   JOURNAL OF CELL BIOLOGY

Endosome–mitochondria interactions are modulated by iron release from transferrin

(2016) Anupam Das et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy

(2016) Shun-ichi Yamashita et al.   JOURNAL OF CELL BIOLOGY

Quadruplex Nucleic Acids as Novel Therapeutic Targets

(2016) Stephen Neidle   JOURNAL OF MEDICINAL CHEMISTRY

ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis

(2016) Jinjiang Fan et al.   MOLECULAR ENDOCRINOLOGY

A heme-binding domain controls regulation of ATP-dependent potassium channels

(2016) Mark J. Burton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of intracellular heme trafficking revealed by subcellular reporters

(2016) Xiaojing Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors

(2016) David A. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome

(2016) Zhantao Yang et al.   Science Translational Medicine

Bacterial Vesicle Secretion and the Evolutionary Origin of the Eukaryotic Endomembrane System

(2016) Sven B. Gould et al.   TRENDS IN MICROBIOLOGY

A Genetically Encoded FRET Sensor for Intracellular Heme

(2015) Yanqun Song et al.   ACS Chemical Biology

Molecular mechanisms of erythrocyte aging

(2015) Richard S. Hoehn et al.   BIOLOGICAL CHEMISTRY

Lessons from bloodless worms: heme homeostasis in C. elegans

(2015) Jason Sinclair et al.   BIOMETALS

Macrophages and iron trafficking at the birth and death of red cells

(2015) T. Korolnek et al.   BLOOD

Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease

(2015) S. M. Camus et al.   BLOOD

Calcium signaling and cell proliferation

(2015) Mauro Cunha Xavier Pinto et al.   CELLULAR SIGNALLING

Role of hemoglobin/heme scavenger protein hemopexin in atherosclerosis and inflammatory diseases

(2015) Niyati U. Mehta et al.   CURRENT OPINION IN LIPIDOLOGY

ER-endosome contact sites: molecular compositions and functions

(2015) C. Raiborg et al.   EMBO JOURNAL

The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation

(2015) S. Mercurio et al.   HAEMATOLOGICA

Shu1 Is a Cell-surface Protein Involved in Iron Acquisition from Heme inSchizosaccharomyces pombe

(2015) Thierry Mourer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs

(2015) Robert S. Jansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histidine residues are important for preserving the structure and heme binding to the C. elegans HRG-3 heme-trafficking protein

(2015) Ortal Marciano et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts

(2015) Andrew Murley et al.   JOURNAL OF CELL BIOLOGY

Genome-Wide Localization Study of Yeast Pex11 Identifies Peroxisome–Mitochondria Interactions through the ERMES Complex

(2015) M. Mattiazzi Ušaj et al.   JOURNAL OF MOLECULAR BIOLOGY

ApoHRP-based assay to measure intracellular regulatory heme

(2015) Hani Atamna et al.   Metallomics

In-Depth, Label-Free Analysis of the Erythrocyte Cytoplasmic Proteome in Diamond Blackfan Anemia Identifies a Unique Inflammatory Signature

(2015) Esther N. Pesciotta et al.   PLoS One

Identification of the Mitochondrial Heme Metabolism Complex

(2015) Amy E. Medlock et al.   PLoS One

PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts

(2015) J. Chung et al.   SCIENCE

Regulation of heme biosynthesis and transport in metazoa

(2015) FengXiu Sun et al.   Science China-Life Sciences

Lam6 Regulates the Extent of Contacts between Organelles

(2015) Yael Elbaz-Alon et al.   Cell Reports

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

(2015) Alberto T Gatta et al.   eLife

The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation

(2015) S. Mercurio et al.   HAEMATOLOGICA

Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders

(2015) Ann Smith et al.   Frontiers in Physiology

The Molecular Biology of Human Iron Metabolism

(2015) William E. Winter et al.   Labmedicine

Protein moonlighting in iron metabolism: glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

(2014) Vishant Mahendra Boradia et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Malarial hemozoin: From target to tool

(2014) Lorena M. Coronado et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

New functions of mitochondria associated membranes in cellular signaling

(2014) Alexander R. van Vliet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Control of Metazoan Heme Homeostasis by a Conserved Multidrug Resistance Protein

(2014) Tamara Korolnek et al.   Cell Metabolism

Heme Enzyme Structure and Function

(2014) Thomas L. Poulos   CHEMICAL REVIEWS

Mitochondria and Melanosomes Establish Physical Contacts Modulated by Mfn2 and Involved in Organelle Biogenesis

(2014) Tiziana Daniele et al.   CURRENT BIOLOGY

A Dynamic Interface between Vacuoles and Mitochondria in Yeast

(2014) Yael Elbaz-Alon et al.   DEVELOPMENTAL CELL

Cellular Metabolism Regulates Contact Sites between Vacuoles and Mitochondria

(2014) Carina Hönscher et al.   DEVELOPMENTAL CELL

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles

(2014) A. Sugiura et al.   EMBO JOURNAL

Heme and erythropoieis: more than a structural role

(2014) D. Chiabrando et al.   HAEMATOLOGICA

Processing of microRNA primary transcripts requires heme in mammalian cells

(2014) Sara H. Weitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hemolysis-induced lethality involves inflammasome activation by heme

(2014) Fabianno F. Dutra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DGCR8 RNA-Binding Heme Domain Recognizes Primary MicroRNAs by Clamping the Hairpin

(2014) Jen Quick-Cleveland et al.   Cell Reports

Iron Metabolism Regulates p53 Signaling through Direct Heme-p53 Interaction and Modulation of p53 Localization, Stability, and Function

(2014) Jia Shen et al.   Cell Reports

A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria

(2014) Sujoy Lahiri et al.   PLOS BIOLOGY

Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

(2014) Deborah Chiabrando et al.   Frontiers in Pharmacology

Like iron in the blood of the people: the requirement for heme trafficking in iron metabolism

(2014) Tamara Korolnek et al.   Frontiers in Pharmacology

Characterization of heme binding to recombinant α1-microglobulin

(2014) Elena Karnaukhova et al.   Frontiers in Physiology

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Organization and function of membrane contact sites

(2013) Sebastian C.J. Helle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ca2+ homeostasis in the endoplasmic reticulum measured with a new low-Ca2+-affinity targeted aequorin

(2013) Sergio de la Fuente et al.   CELL CALCIUM

HRG1 Is Essential for Heme Transport from the Phagolysosome of Macrophages during Erythrophagocytosis

(2013) Carine White et al.   Cell Metabolism

Heme transport and erythropoiesis

(2013) Xiaojing Yuan et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

An ER-peroxisome tether exerts peroxisome population control in yeast

(2013) Barbara Knoblach et al.   EMBO JOURNAL

Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states

(2013) Peter Hahl et al.   JOURNAL OF NEUROCHEMISTRY

Heme and FLVCR-related transporter families SLC48 and SLC49

(2013) Anwar A. Khan et al.   MOLECULAR ASPECTS OF MEDICINE

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

(2013) Estelle Woldt et al.   NATURE MEDICINE

Detection of G-quadruplex DNA in mammalian cells

(2013) A. Henderson et al.   NUCLEIC ACIDS RESEARCH

Human housekeeping genes, revisited

(2013) Eli Eisenberg et al.   TRENDS IN GENETICS

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast

(2013) Andrew Murley et al.   eLife

Trapping of Human Hemoglobin by Haptoglobin: Molecular Mechanisms and Clinical Applications

(2012) Khuanpiroon Ratanasopa et al.   ANTIOXIDANTS & REDOX SIGNALING

ABC transporters and their role in nucleoside and nucleotide drug resistance

(2012) Yu Fukuda et al.   BIOCHEMICAL PHARMACOLOGY

Heme Binding Properties of Glyceraldehyde-3-phosphate Dehydrogenase

(2012) Luciana Hannibal et al.   BIOCHEMISTRY

One ring to rule them all: Trafficking of heme and heme synthesis intermediates in the metazoans

(2012) Iqbal Hamza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

(2012) D. J. Schaer et al.   BLOOD

Preliminary characterization of the murine membrane reticulocyte proteome

(2012) Jessica E. Prenni et al.   BLOOD CELLS MOLECULES AND DISEASES

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

(2012) Vincent Soubannier et al.   CURRENT BIOLOGY

Heme metabolism and erythropoiesis

(2012) Jacky Chung et al.   CURRENT OPINION IN HEMATOLOGY

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology

(2012) Andrew G. Manford et al.   DEVELOPMENTAL CELL

Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol

(2012) Y. Gottlieb et al.   HAEMATOLOGICA

Heme Utilization in theCaenorhabditis elegansHypodermal Cells Is Facilitated by Heme-responsive Gene-2

(2012) Caiyong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae

(2012) C. Voss et al.   JOURNAL OF CELL SCIENCE

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

(2012) Deborah Chiabrando et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages and Systemic Iron Homeostasis

(2012) Tomas Ganz   Journal of Innate Immunity

Crystallographic studies of heme oxygenase complexed with an unstable reaction intermediate, verdoheme

(2012) Masaki Unno et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Null alleles of ABCG2 encoding the breast cancer resistance protein define the new blood group system Junior

(2012) Carole Saison et al.   NATURE GENETICS

STIM proteins: dynamic calcium signal transducers

(2012) Jonathan Soboloff et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo

(2012) Vincent Soubannier et al.   PLoS One

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

(2012) I. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gem1 and ERMES Do Not Directly Affect Phosphatidylserine Transport from ER to Mitochondria or Mitochondrial Inheritance

(2012) Tammy T. Nguyen et al.   TRAFFIC

The β1a Subunit of the Skeletal DHPR Binds to Skeletal RyR1 and Activates the Channel via Its 35-Residue C-Terminal Tail

(2011) Robyn T. Rebbeck et al.   BIOPHYSICAL JOURNAL

An Intercellular Heme-Trafficking Protein Delivers Maternal Heme to the Embryo during Development in C. elegans

(2011) Caiyong Chen et al.   CELL

Nitric Oxide Scavenging by Red Blood Cell Microparticles and Cell-Free Hemoglobin as a Mechanism for the Red Cell Storage Lesion

(2011) Chenell Donadee et al.   CIRCULATION

RNA and DNA complexes with hemin [Fe(III) heme] are efficient peroxidases and peroxygenases: how do they do it and what does it mean?

(2011) Dipankar Sen et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Role for cER and Mmr1p in Anchorage of Mitochondria at Sites of Polarized Surface Growth in Budding Yeast

(2011) Theresa C. Swayne et al.   CURRENT BIOLOGY

Lipid transfer and signaling at organelle contact sites: the tip of the iceberg

(2011) Alexandre Toulmay et al.   CURRENT OPINION IN CELL BIOLOGY

Mammalian multidrug-resistance proteins (MRPs)

(2011) Andrew J. Slot et al.   Essays in Biochemistry

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

(2011) Kurt J. De Vos et al.   HUMAN MOLECULAR GENETICS

Topologically Conserved Residues Direct Heme Transport in HRG-1-related Proteins

(2011) Xiaojing Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guanine-Rich RNAs and DNAs That Bind Heme Robustly Catalyze Oxygen Transfer Reactions

(2011) Lester C.-H. Poon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections

(2011) B. Kornmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Storage lesion: role of red blood cell breakdown

(2011) Daniel B. Kim-Shapiro et al.   TRANSFUSION

Ca2+ Signaling During Mammalian Fertilization: Requirements, Players, and Adaptations

(2011) T. Wakai et al.   Cold Spring Harbor Perspectives in Biology

Multidrug resistance associated proteins in multidrug resistance

(2011) Kamlesh Sodani et al.   Chinese Journal of Cancer

Mutations in FLVCR2 Are Associated with Proliferative Vasculopathy and Hydranencephaly-Hydrocephaly Syndrome (Fowler Syndrome)

(2010) Esther Meyer et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Copper Metallochaperones

(2010) Nigel J. Robinson et al.   Annual Review of Biochemistry

Heme and non-heme iron transporters in non-polarized and polarized cells

(2010) Izumi Yanatori et al.   BMC CELL BIOLOGY

Cardiac Copper Deficiency Activates a Systemic Signaling Mechanism that Communicates with the Copper Acquisition and Storage Organs

(2010) Byung-Eun Kim et al.   Cell Metabolism

Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction

(2010) Ryota Iwasawa et al.   EMBO JOURNAL

ABCG2 Transports and Transfers Heme to Albumin through Its Large Extracellular Loop

(2010) Elodie Desuzinges-Mandon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Iron and Porphyrin Trafficking in Heme Biogenesis

(2010) Iman J. Schultz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetics and Specificity of Feline Leukemia Virus Subgroup C Receptor (FLVCR) Export Function and Its Dependence on Hemopexin

(2010) Zhantao Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tetrapyrrole binding affinity of the murine and human p22HBP heme-binding proteins

(2010) Nuno M. Micaelo et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

The Fowler Syndrome-Associated Protein FLVCR2 Is an Importer of Heme

(2010) S. P. Duffy et al.   MOLECULAR AND CELLULAR BIOLOGY

GAPDH regulates cellular heme insertion into inducible nitric oxide synthase

(2010) R. Chakravarti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification

(2009) P. W. Buehler et al.   BLOOD

Trafficking of Heme and Porphyrins in Metazoa

(2009) Scott Severance et al.   CHEMICAL REVIEWS

Negative feedback maintenance of heme homeostasis by its receptor, Rev-erb 

(2009) N. Wu et al.   GENES & DEVELOPMENT

Heme-binding Protein HRG-1 Is Induced by Insulin-like Growth Factor I and Associates with the Vacuolar H+-ATPase to Control Endosomal pH and Receptor Trafficking

(2009) Katie M. O'Callaghan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mss51 and Ssc1 Facilitate Translational Regulation of Cytochrome c Oxidase Biogenesis

(2009) F. Fontanesi et al.   MOLECULAR AND CELLULAR BIOLOGY

GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

(2009) Renata Sano et al.   MOLECULAR CELL

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

ABCG2: A perspective

(2008) Robert W. Robey et al.   ADVANCED DRUG DELIVERY REVIEWS

Hemopexin Prevents Endothelial Damage and Liver Congestion in a Mouse Model of Heme Overload

(2008) Francesca Vinchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Cargo-Selected Transport from the Mitochondria to Peroxisomes Is Mediated by Vesicular Carriers

(2008) Margaret Neuspiel et al.   CURRENT BIOLOGY

The Role of Oxidative Stress in Hemolytic Anemia

(2008) Eitan Fibach et al.   CURRENT MOLECULAR MEDICINE

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)

(2008) Gergely Szakács et al.   DRUG DISCOVERY TODAY

Heme Transport and Detoxification in Nematodes: Subproteomics Evidence of Differential Role of Glutathione Transferases

(2008) Samïrah Perally et al.   JOURNAL OF PROTEOME RESEARCH

Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides

(2008) C. de Wolf et al.   MOLECULAR CANCER THERAPEUTICS

Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins

(2008) Abbhirami Rajagopal et al.   NATURE

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin

(2008) Yoshihiro Dohi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis

(2008) S. B. Keel et al.   SCIENCE

Special delivery from mitochondria to peroxisomes

(2008) Uwe Schumann et al.   TRENDS IN CELL BIOLOGY