Processing of microRNA primary transcripts requires heme in mammalian cells

Regulation of miRNA biogenesis as an integrated component of growth factor signaling

(2013) Matthew T Blahna et al.   CURRENT OPINION IN CELL BIOLOGY

Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8

(2012) Taeko Wada et al.   EMBO REPORTS

Dimerization and Heme Binding Are Conserved in Amphibian and Starfish Homologues of the microRNA Processing Protein DGCR8

(2012) Rachel Senturia et al.   PLoS One

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

(2012) I. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspases cleave and inhibit the microRNA processing protein DiGeorge Critical Region 8

(2012) Ming Gong et al.   PROTEIN SCIENCE

MicroRNA turnover: when, how, and why

(2012) Stefan Rüegger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heme Oxygenase-1 Inhibits Myoblast Differentiation by Targeting Myomirs

(2011) Magdalena Kozakowska et al.   ANTIOXIDANTS & REDOX SIGNALING

In-vivo quantification of primary microRNA processing by Drosha with a luciferase based system

(2011) Danilo Allegra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

MicroRNAs and developmental timing

(2011) Victor Ambros   CURRENT OPINION IN GENETICS & DEVELOPMENT

DiGeorge Critical Region 8 (DGCR8) Is a Double-cysteine-ligated Heme Protein

(2011) Ian Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

Identification of microprocessor-dependent cancer cells allows screening for growth-sustaining micro-RNAs

(2011) D Peric et al.   ONCOGENE

Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex

(2011) K. Fenelon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Structure of the dimerization domain of DiGeorge Critical Region 8

(2010) Rachel Senturia et al.   PROTEIN SCIENCE

DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures

(2010) M. Faller et al.   RNA

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Post-transcriptional control of DGCR8 expression by the Microprocessor

(2009) R. Triboulet et al.   RNA

Establishment of cells to monitor Microprocessor through fusion genes of microRNA and GFP

(2008) Motomu Tsutsui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS