The regulation of mitochondrial homeostasis by the ubiquitin proteasome system

Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane

(2020) Pin-Chao Liao et al.   Cell Reports

Mitochondrial proteins: from biogenesis to functional networks

(2019) Nikolaus Pfanner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme

(2019) Felix Boos et al.   NATURE CELL BIOLOGY

Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL

(2019) Fumika Koyano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rsp5 and Mdm30 reshape the mitochondrial network in response to age-induced vacuole stress

(2019) Jenna M. Goodrum et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial protein translocation-associated degradation

(2019) Christoph U. Mårtensson et al.   NATURE

Selective Autophagy: ATG8 Family Proteins, LIR Motifs and Cargo Receptors

(2019) Terje Johansen et al.   JOURNAL OF MOLECULAR BIOLOGY

Physics-based oligomeric models of the yeast mitofusin Fzo1 at the molecular scale in the context of membrane docking

(2019) Astrid Brandner et al.   MITOCHONDRION

Endoplasmic reticulum–mitochondria crosstalk: from junction to function across neurological disorders

(2019) Pabbala Veeresh et al.   Annals of the New York Academy of Sciences

Identification of a mitofusin specificity region that confers unique activities to Mfn1 and Mfn2

(2019) S. R. Sloat et al.   MOLECULAR BIOLOGY OF THE CELL

Msp1 Clears Mistargeted Proteins by Facilitating Their Transfer from Mitochondria to the ER

(2019) Shunsuke Matsumoto et al.   MOLECULAR CELL

Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts

(2019) Rajat Puri et al.   Nature Communications

Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset

(2019) Yu-Jie Li et al.   Nature Communications

A AAA ATPase Cdc48 with a cofactor Ubx2 facilitates ubiquitylation of a mitochondrial fusion-promoting factor Fzo1 for proteasomal degradation

(2019) Sabiqun Nahar et al.   JOURNAL OF BIOCHEMISTRY

Structure and Function of the 26S Proteasome

(2018) Jared A.M. Bard et al.   Annual Review of Biochemistry

PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol

(2018) Shiori Sekine et al.   BMC BIOLOGY

Mechanistic insights into ER-associated protein degradation

(2018) Xudong Wu et al.   CURRENT OPINION IN CELL BIOLOGY

The role of mitochondria in stem cell fate and aging

(2018) Hongbo Zhang et al.   DEVELOPMENT

Two Cdc48 cofactors Ubp3 and Ubx2 regulate mitochondrial morphology and protein turnover

(2018) Abhijit Chowdhury et al.   JOURNAL OF BIOCHEMISTRY

Cytosolic Hsp70 and Hsp40 chaperones enable the biogenesis of mitochondrial β-barrel proteins

(2018) Tobias Jores et al.   JOURNAL OF CELL BIOLOGY

Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion

(2018) Liming Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MitoCPR—A surveillance pathway that protects mitochondria in response to protein import stress

(2018) Hilla Weidberg et al.   SCIENCE

Mitochondrial dynamics: The dynamin superfamily and execution by collusion

(2018) Rajesh Ramachandran   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Vms1p is a release factor for the ribosome-associated quality control complex

(2018) Olga Zurita Rendón et al.   Nature Communications

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

(2018) Nadav Shai et al.   Nature Communications

Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion

(2018) Liming Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ubiquitin-Dependent Degradation of Mitochondrial Proteins Regulates Energy Metabolism

(2018) Julie Lavie et al.   Cell Reports

Cdc48 regulates a deubiquitylase cascade critical for mitochondrial fusion

(2018) Tânia Simões et al.   eLife

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

(2018) Gian-Luca McLelland et al.   eLife

Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes

(2018) Rati Verma et al.   NATURE

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

(2018) Konstantinos Palikaras et al.   NATURE CELL BIOLOGY

Regulation of Endoplasmic Reticulum-Mitochondria contacts by Parkin via Mfn2

(2018) Valentina Basso et al.   PHARMACOLOGICAL RESEARCH

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

(2018) Anthea Di Rita et al.   Nature Communications

Lipid exchange at ER-mitochondria contact sites: a puzzle falling into place with quite a few pieces missing

(2018) Carmelina Petrungaro et al.   CURRENT OPINION IN CELL BIOLOGY

Cell Biology of the Mitochondrion

(2017) Alexander M. van der Bliek et al.   GENETICS

A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space

(2017) Sevan Mattie et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins

(2017) Matthew L. Wohlever et al.   MOLECULAR CELL

MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion

(2017) Yu-Lu Cao et al.   NATURE

CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides

(2017) Kamena K. Kostova et al.   SCIENCE

The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

(2017) Yong Tae Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES

With the Help of MOM: Mitochondrial Contributions to Cellular Quality Control

(2017) Ralf J. Braun et al.   TRENDS IN CELL BIOLOGY

A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance

(2017) Babette C. Hammerling et al.   Nature Communications

An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion

(2017) Laetitia Cavellini et al.   Nature Communications

Control of mitochondrial biogenesis and function by the ubiquitin–proteasome system

(2017) Piotr Bragoszewski et al.   Open Biology

Ubiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin

(2017) Sora Lee et al.   eLife

Cell Biology of the Mitochondrion

(2017) Alexander M. van der Bliek et al.   GENETICS

A membrane-inserted structural model of the yeast mitofusin Fzo1

(2017) Dario De Vecchis et al.   Scientific Reports

Ubiquitination of ERMES components by the E3 ligase Rsp5 is involved in mitophagy

(2016) Naïma Belgareh-Touzé et al.   Autophagy

Ubiquitination of specific mitochondrial matrix proteins

(2016) Gilad Lehmann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The coming of age of the mitochondria–ER contact: a matter of thickness

(2016) M Giacomello et al.   CELL DEATH AND DIFFERENTIATION

E2 enzymes: more than just middle men

(2016) Mikaela D Stewart et al.   CELL RESEARCH

A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites

(2016) Michal Eisenberg-Bord et al.   DEVELOPMENTAL CELL

Structure and function of the AAA+ ATPase p97/Cdc48p

(2016) Di Xia et al.   GENE

Heat Shock Protein 90 kDa (Hsp90) Has a Second Functional Interaction Site with the Mitochondrial Import Receptor Tom70

(2016) Leticia M. Zanphorlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Doa1 targets ubiquitinated substrates for mitochondria-associated degradation

(2016) Xi Wu et al.   JOURNAL OF CELL BIOLOGY

Structures of human mitofusin 1 provide insight into mitochondrial tethering

(2016) Yuanbo Qi et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis

(2016) Rukmini Mukherjee et al.   JOURNAL OF CELL SCIENCE

An overview of macroautophagy in yeast

(2016) Xin Wen et al.   JOURNAL OF MOLECULAR BIOLOGY

Mitofusins, from Mitochondria to Metabolism

(2016) Emilie Schrepfer et al.   MOLECULAR CELL

The Mitochondrial Basis of Aging

(2016) Nuo Sun et al.   MOLECULAR CELL

Failure of RQC machinery causes protein aggregation and proteotoxic stress

(2016) Young-Jun Choe et al.   NATURE

The increasing complexity of the ubiquitin code

(2016) Richard Yau et al.   NATURE CELL BIOLOGY

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

(2016) Deborah Naon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

(2016) Thanh N. Nguyen et al.   TRENDS IN CELL BIOLOGY

Deubiquitinase activity is required for the proteasomal degradation of misfolded cytosolic proteins upon heat-stress

(2016) Nancy N. Fang et al.   Nature Communications

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation

(2016) Ryo Yonashiro et al.   eLife

A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro

(2016) Tobias Brandt et al.   eLife

Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes

(2016) Christopher M. Rose et al.   Cell Systems

Mitochondrial proteases and protein quality control in ageing and longevity

(2015) Marie-Paule Hamon et al.   AGEING RESEARCH REVIEWS

Deubiquitinating enzymes regulate PARK2-mediated mitophagy

(2015) Yuqing Wang et al.   Autophagy

BCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32

(2015) Kinya Otsu et al.   Autophagy

Redox Homeostasis and Mitochondrial Dynamics

(2015) Peter H.G.M. Willems et al.   Cell Metabolism

A Ubl/ubiquitin switch in the activation of Parkin

(2015) V. Sauve et al.   EMBO JOURNAL

Phosphorylated ubiquitin chain is the genuine Parkin receptor

(2015) Kei Okatsu et al.   JOURNAL OF CELL BIOLOGY

Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment

(2015) K. Okatsu et al.   JOURNAL OF CELL SCIENCE

A Perspective on Transport of Proteins into Mitochondria: A Myriad of Open Questions

(2015) Walter Neupert   JOURNAL OF MOLECULAR BIOLOGY

MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death

(2015) Julien Prudent et al.   MOLECULAR CELL

A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death

(2015) Xiaowen Wang et al.   NATURE

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

(2015) Lidia Wrobel et al.   NATURE

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling

(2015) Riccardo Filadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retro-translocation of mitochondrial intermembrane space proteins

(2015) Piotr Bragoszewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly

(2015) Andrew P. AhYoung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains

(2015) P. S. Shen et al.   SCIENCE

The demographics of the ubiquitin system

(2015) Michael J. Clague et al.   TRENDS IN CELL BIOLOGY

Synthetic Quantitative Array Technology Identifies the Ubp3-Bre5 Deubiquitinase Complex as a Negative Regulator of Mitophagy

(2015) Matthias Müller et al.   Cell Reports

Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition

(2015) Zhu Liu et al.   eLife

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

(2014) Agne Kazlauskaite et al.   BIOCHEMICAL JOURNAL

Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family

(2014) Kefeng Lu et al.   CELL

AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1

(2014) F Strappazzon et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial ER Contacts Are Crucial for Mitophagy in Yeast

(2014) Stefan Böckler et al.   DEVELOPMENTAL CELL

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles

(2014) A. Sugiura et al.   EMBO JOURNAL

USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin

(2014) T. M. Durcan et al.   EMBO JOURNAL

Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins

(2014) Y.-C. Chen et al.   EMBO JOURNAL

The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy

(2014) Tom Cornelissen et al.   HUMAN MOLECULAR GENETICS

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

(2014) Lesley A. Kane et al.   JOURNAL OF CELL BIOLOGY

Ubiquitylation by the Ltn1 E3 ligase protects 60S ribosomes from starvation-induced selective autophagy

(2014) Batool Ossareh-Nazari et al.   JOURNAL OF CELL BIOLOGY

Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis

(2014) Alban Ordureau et al.   MOLECULAR CELL

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

(2014) Baris Bingol et al.   NATURE

Clearing tail-anchored proteins from mitochondria

(2014)  ukasz Opali ski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins

(2014) V. Okreglak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Mitochondrial Polyubiquitin by PINK1 Promotes Parkin Mitochondrial Tethering

(2014) Kahori Shiba-Fukushima et al.   PLoS Genetics

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

(2014) Jina Yun et al.   eLife

Variants of mitochondrial autophagy: Types 1 and 2 mitophagy and micromitophagy (Type 3)

(2014) John J. Lemasters   Redox Biology

Mitochondria-type GPAT is required for mitochondrial fusion

(2013) Yohsuke Ohba et al.   EMBO JOURNAL

Structure of the human Parkin ligase domain in an autoinhibited state

(2013) Tobias Wauer et al.   EMBO JOURNAL

A Dimeric PINK1-containing Complex on Depolarized Mitochondria Stimulates Parkin Recruitment

(2013) Kei Okatsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ubiquitin-Proteasome System Regulates Mitochondrial Intermembrane Space Proteins

(2013) P. Bragoszewski et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase

(2013) Min Fu et al.   MOLECULAR BIOLOGY OF THE CELL

Two Deubiquitylases Act on Mitofusin and Regulate Mitochondrial Fusion along Independent Pathways

(2013) Fabian Anton et al.   MOLECULAR CELL

MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2

(2013) Ayumu Sugiura et al.   MOLECULAR CELL

A Lipid E-MAP Identifies Ubx2 as a Critical Regulator of Lipid Saturation and Lipid Bilayer Stress

(2013) Michal A. Surma et al.   MOLECULAR CELL

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

(2013) Shireen A. Sarraf et al.   NATURE

Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products

(2013) Q. Defenouillere et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation

(2013) J.-F. Trempe et al.   SCIENCE

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease

(2013) Donald E. Spratt et al.   Nature Communications

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

(2013) B.E. Riley et al.   Nature Communications

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress

(2012) Onn Brandman et al.   CELL

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

(2012) Vincent Soubannier et al.   CURRENT BIOLOGY

Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin

(2012) Michael Lazarou et al.   DEVELOPMENTAL CELL

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

(2012) Andrew W Greene et al.   EMBO REPORTS

Cdc48p/p97-mediated regulation of mitochondrial morphology is Vms1p-independent

(2012) Masatoshi Esaki et al.   JOURNAL OF STRUCTURAL BIOLOGY

Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis

(2012) Guillaume P. Leboucher et al.   MOLECULAR CELL

Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study

(2012) Pierre Cosson et al.   PLoS One

Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo

(2012) Vincent Soubannier et al.   PLoS One

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria

(2012) Kei Okatsu et al.   Nature Communications

Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

(2011) Nickie C. Chan et al.   HUMAN MOLECULAR GENETICS

Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane

(2011) Saori R. Yoshii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion

(2011) F. Anton et al.   JOURNAL OF CELL SCIENCE

Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion

(2011) M. M. Cohen et al.   JOURNAL OF CELL SCIENCE

Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease

(2011) Tom Bender et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphorylation of Serine 114 on Atg32 mediates mitophagy

(2011) Yoshimasa Aoki et al.   MOLECULAR BIOLOGY OF THE CELL

Image-based genome-wide siRNA screen identifies selective autophagy factors

(2011) Anthony Orvedahl et al.   NATURE

Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria

(2010) Klaus O. Kopec et al.   BIOINFORMATICS

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

(2010) Matthew E. Gegg et al.   HUMAN MOLECULAR GENETICS

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Degradation of an intramitochondrial protein by the cytosolic proteasome

(2010) V. Azzu et al.   JOURNAL OF CELL SCIENCE

A Stress-Responsive System for Mitochondrial Protein Degradation

(2010) Jin-Mi Heo et al.   MOLECULAR CELL

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

(2010) Mario H. Bengtson et al.   NATURE

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dom34:Hbs1 Promotes Subunit Dissociation and Peptidyl-tRNA Drop-Off to Initiate No-Go Decay

(2010) C. J. Shoemaker et al.   SCIENCE

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy

(2009) Koji Okamoto et al.   DEVELOPMENTAL CELL

MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

(2009) Emélie Braschi et al.   EMBO REPORTS

Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity

(2009) H. C. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

A Mutation Associated with CMT2A Neuropathy Causes Defects in Fzo1 GTP Hydrolysis, Ubiquitylation, and Protein Turnover

(2009) Elizabeth A. Amiott et al.   MOLECULAR BIOLOGY OF THE CELL

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

(2009) M. Harreman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin–Proteasome-dependent Degradation of a Mitofusin, a Critical Regulator of Mitochondrial Fusion

(2008) Mickael M.J. Cohen et al.   MOLECULAR BIOLOGY OF THE CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE