PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol
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Title
PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol
Authors
Keywords
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Journal
BMC BIOLOGY
Volume 16, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-01-10
DOI
10.1186/s12915-017-0470-7
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Note: Only part of the references are listed.- Mitochondrial fission facilitates the selective mitophagy of protein aggregates
- (2017) Jonathon L. Burman et al. JOURNAL OF CELL BIOLOGY
- PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis
- (2017) Shotaro Saita et al. NATURE CELL BIOLOGY
- Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import
- (2017) Ireos Filipuzzi et al. Nature Chemical Biology
- PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival
- (2017) Yunjong Lee et al. Cell Reports
- PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?
- (2017) Dominika Truban et al. Journal of Parkinsons Disease
- The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation
- (2016) Koji Yamano et al. EMBO REPORTS
- The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i ‐AAA protease YME1L
- (2016) Timothy Wai et al. EMBO REPORTS
- Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
- (2016) Benjamin Richter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PARL: The mitochondrial rhomboid protease
- (2016) Marco Spinazzi et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Deciphering the Molecular Signals of PINK1/Parkin Mitophagy
- (2016) Thanh N. Nguyen et al. TRENDS IN CELL BIOLOGY
- Mitochondrial Antigen Presentation: A Vacuolar Path to Autoimmunity in Parkinson's Disease
- (2016) Pascale Baden et al. TRENDS IN IMMUNOLOGY
- Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
- (2016) Rebecca Rojansky et al. eLife
- (Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation
- (2015) F. C. Fiesel et al. EMBO REPORTS
- Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment
- (2015) K. Okatsu et al. JOURNAL OF CELL SCIENCE
- The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
- (2015) Jin-Mi Heo et al. MOLECULAR CELL
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- New roles for mitochondrial proteases in health, ageing and disease
- (2015) Pedro M. Quirós et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
- (2015) Alicia M. Pickrell et al. NEURON
- Molecular architecture of the active mitochondrial protein gate
- (2015) T. Shiota et al. SCIENCE
- The Rhomboid-Like Superfamily: Molecular Mechanisms and Biological Roles
- (2014) Matthew Freeman Annual Review of Cell and Developmental Biology
- Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
- (2014) Agne Kazlauskaite et al. BIOCHEMICAL JOURNAL
- Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis
- (2014) T. Wauer et al. EMBO JOURNAL
- Roles of mitochondrial ubiquitin ligase MITOL/MARCH5 in mitochondrial dynamics and diseases
- (2014) S. Nagashima et al. JOURNAL OF BIOCHEMISTRY
- Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
- (2014) Ghazaleh Ashrafi et al. JOURNAL OF CELL BIOLOGY
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
- (2014) Alban Ordureau et al. MOLECULAR CELL
- Ubiquitin is phosphorylated by PINK1 to activate parkin
- (2014) Fumika Koyano et al. NATURE
- PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
- (2014) V. A. Morais et al. SCIENCE
- PINK1-Parkin Pathway Activity Is Regulated by Degradation of PINK1 in the Mitochondrial Matrix
- (2014) Ruth E. Thomas et al. PLoS Genetics
- PINK1 is degraded through the N-end rule pathway
- (2013) Koji Yamano et al. Autophagy
- The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
- (2013) Seok Min Jin et al. Autophagy
- A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1
- (2013) Nicholas T. Hertz et al. CELL
- A Dimeric PINK1-containing Complex on Depolarized Mitochondria Stimulates Parkin Recruitment
- (2013) Kei Okatsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
- (2013) Samuel A. Hasson et al. NATURE
- The N-End Rule Pathway
- (2012) Takafumi Tasaki et al. Annual Review of Biochemistry
- Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
- (2012) Michael Lazarou et al. DEVELOPMENTAL CELL
- Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
- (2012) Andrew W Greene et al. EMBO REPORTS
- Analysis of the regulatory and catalytic domains of PTEN-induced kinase-1 (PINK1)
- (2012) Chou Hung Sim et al. HUMAN MUTATION
- Rhomboid Protease PARL Mediates the Mitochondrial Membrane Potential Loss-induced Cleavage of PGAM5
- (2012) Shiori Sekine et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrates of IAP Ubiquitin Ligases Identified with a Designed Orthogonal E3 Ligase, the NEDDylator
- (2012) Min Zhuang et al. MOLECULAR CELL
- Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation
- (2012) A. M. Nargund et al. SCIENCE
- PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
- (2012) Kei Okatsu et al. Nature Communications
- PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
- (2012) Kahori Shiba-Fukushima et al. Scientific Reports
- PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
- (2012) C. Kondapalli et al. Open Biology
- Lateral release of proteins from the TOM complex into the outer membrane of mitochondria
- (2011) Max Harner et al. EMBO JOURNAL
- The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
- (2011) Cathrin Meissner et al. JOURNAL OF NEUROCHEMISTRY
- The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
- (2010) Sven Geisler et al. Autophagy
- PINK1 cleavage at position A103 by the mitochondrial protease PARL
- (2010) Emma Deas et al. HUMAN MOLECULAR GENETICS
- Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
- (2010) Seok Min Jin et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- Intramembrane Proteolysis of Mgm1 by the Mitochondrial Rhomboid Protease Is Highly Promiscuous Regarding the Sequence of the Cleaved Hydrophobic Segment
- (2010) Anja Schäfer et al. JOURNAL OF MOLECULAR BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Prohibitins and the functional compartmentalization of mitochondrial membranes
- (2009) C. Osman et al. JOURNAL OF CELL SCIENCE
- Sequence-Specific Intramembrane Proteolysis: Identification of a Recognition Motif in Rhomboid Substrates
- (2009) Kvido Strisovsky et al. MOLECULAR CELL
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
- (2008) A. J. Whitworth et al. Disease Models & Mechanisms
- Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria
- (2008) C. Merkwirth et al. GENES & DEVELOPMENT
- Step-size Analyses of the Mitochondrial Hsp70 Import Motor Reveal the Brownian Ratchet in Operation
- (2008) Koji Yamano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Characterization of PINK1 processing, stability, and subcellular localization
- (2008) William Lin et al. JOURNAL OF NEUROCHEMISTRY
- The kinase domain of mitochondrial PINK1 faces the cytoplasm
- (2008) C. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1
- (2007) Sho Takatori et al. NEUROSCIENCE LETTERS
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