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Title
Phosphorylated ubiquitin chain is the genuine Parkin receptor
Authors
Keywords
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Journal
JOURNAL OF CELL BIOLOGY
Volume 209, Issue 1, Pages 111-128
Publisher
Rockefeller University Press
Online
2015-04-07
DOI
10.1083/jcb.201410050
References
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Related references
Note: Only part of the references are listed.- Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
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- PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
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- PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
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- Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria
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- Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
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- Parkin Mediates Apparent E2-Independent Monoubiquitination In Vitro and Contains an Intrinsic Activity That Catalyzes Polyubiquitination
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- p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
- (2010) Derek Narendra et al. Autophagy
- p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
- (2010) Kei Okatsu et al. GENES TO CELLS
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
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- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
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- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
- (2010) Angela C. Poole et al. PLoS One
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome
- (2009) Yasushi Saeki et al. EMBO JOURNAL
- Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
- (2009) David Komander et al. EMBO REPORTS
- Pex2 and Pex12 Function as Protein-Ubiquitin Ligases in Peroxisomal Protein Import
- (2009) H. W. Platta et al. MOLECULAR AND CELLULAR BIOLOGY
- A Ubiquitin Replacement Strategy in Human Cells Reveals Distinct Mechanisms of IKK Activation by TNFα and IL-1β
- (2009) Ming Xu et al. MOLECULAR CELL
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies
- (2008) Kim Newton et al. CELL
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
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