Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice
Authors
Keywords
-
Journal
AGING CELL
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2021-01-20
DOI
10.1111/acel.13296
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Anti‐inflammatory treatment rescues memory deficits during aging in nfkb1 −/− mice
- (2020) Edward Fielder et al. AGING CELL
- Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis
- (2019) Mikolaj Ogrodnik et al. Cell Metabolism
- Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS
- (2019) Emiliano Trias et al. Frontiers in Aging Neuroscience
- Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis
- (2019) Alexandra M. Nicaise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- L1 drives IFN in senescent cells and promotes age-associated inflammation
- (2019) Marco De Cecco et al. NATURE
- Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
- (2019) Allyson K. Palmer et al. AGING CELL
- Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
- (2019) Peisu Zhang et al. NATURE NEUROSCIENCE
- Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes
- (2019) Cristina Aguayo-Mazzucato et al. Cell Metabolism
- Single-cell analysis reveals T cell infiltration in old neurogenic niches
- (2019) Ben W. Dulken et al. NATURE
- Ageing as a risk factor for neurodegenerative disease
- (2019) Yujun Hou et al. Nature Reviews Neurology
- Senolytics improve physical function and increase lifespan in old age
- (2018) Ming Xu et al. NATURE MEDICINE
- Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease
- (2018) Shankar J. Chinta et al. Cell Reports
- Tau protein aggregation is associated with cellular senescence in the brain
- (2018) Nicolas Musi et al. AGING CELL
- Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
- (2018) Tyler J. Bussian et al. NATURE
- Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells
- (2018) Mikolaj Ogrodnik et al. AGING CELL
- Impaired immune surveillance accelerates accumulation of senescent cells and aging
- (2018) Yossi Ovadya et al. Nature Communications
- Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the aging brain
- (2017) Antonio Currais et al. FASEB JOURNAL
- Senescence and aging: Causes, consequences, and therapeutic avenues
- (2017) Domhnall McHugh et al. JOURNAL OF CELL BIOLOGY
- Cellular senescence drives age-dependent hepatic steatosis
- (2017) Mikolaj Ogrodnik et al. Nature Communications
- Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
- (2016) Brandon M. Hall et al. Aging-US
- Quercetin and the mitochondria: A mechanistic view
- (2016) Marcos Roberto de Oliveira et al. BIOTECHNOLOGY ADVANCES
- Mitochondria and Synaptic Plasticity in the Mature and Aging Nervous System
- (2016) Vyara Todorova et al. Current Neuropharmacology
- Mitochondria are required for pro‐ageing features of the senescent phenotype
- (2016) Clara Correia‐Melo et al. EMBO JOURNAL
- Energy metabolism and inflammation in brain aging and Alzheimer’s disease
- (2016) Fei Yin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury
- (2016) Rodney M. Ritzel et al. JOURNAL OF IMMUNOLOGY
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Genomic integrity and the ageing brain
- (2015) Hei-man Chow et al. NATURE REVIEWS NEUROSCIENCE
- Targeting senescent cells enhances adipogenesis and metabolic function in old age
- (2015) Ming Xu et al. eLife
- Immunosurveillance of senescent cells: the bright side of the senescence program
- (2013) Adi Sagiv et al. BIOGERONTOLOGY
- Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape
- (2013) P. P. Shah et al. GENES & DEVELOPMENT
- p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
- (2013) Albert R. Davalos et al. JOURNAL OF CELL BIOLOGY
- A complex secretory program orchestrated by the inflammasome controls paracrine senescence
- (2013) Juan Carlos Acosta et al. NATURE CELL BIOLOGY
- A senescent cell bystander effect: senescence-induced senescence
- (2012) Glyn Nelson et al. AGING CELL
- Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response
- (2012) Diana Jurk et al. AGING CELL
- Pulmonary Arterial Hypertension in Patients Treated by Dasatinib
- (2012) David Montani et al. CIRCULATION
- Age-associated learning and memory deficits in two mouse versions of the stone T-maze
- (2012) Paul J. Pistell et al. NEUROBIOLOGY OF AGING
- Review: Microglia of the aged brain: primed to be activated and resistant to regulation
- (2012) D. M. Norden et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
- (2012) Graeme Hewitt et al. Nature Communications
- Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats
- (2011) Akari Ishisaka et al. FREE RADICAL BIOLOGY AND MEDICINE
- The role of nuclear lamin B1 in cell proliferation and senescence
- (2011) T. Shimi et al. GENES & DEVELOPMENT
- Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
- (2011) Tae-Won Kang et al. NATURE
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Mitochondrial dysfunction in brain aging: Role of oxidative stress and cardiolipin
- (2011) Giuseppe Paradies et al. NEUROCHEMISTRY INTERNATIONAL
- Microglia in the aging brain: relevance to neurodegeneration
- (2010) Xiao-Guang Luo et al. Molecular Neurodegeneration
- Development of a water-escape motivated version of the Stone T-maze for mice
- (2009) P.J. Pistell et al. NEUROSCIENCE
- Cell surface-bound IL-1 is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
- (2009) A. V. Orjalo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia
- (2008) K. Porkka et al. BLOOD
- Oxidative Damage and Cognitive Dysfunction: Antioxidant Treatments to Promote Healthy Brain Aging
- (2008) Elizabeth Head NEUROCHEMICAL RESEARCH
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- (2008) Jean-Philippe Coppé et al. PLOS BIOLOGY
- Flavonoids induce HIF-1α but impair its nuclear accumulation and activity
- (2007) Anastasia Triantafyllou et al. FREE RADICAL BIOLOGY AND MEDICINE
- Impaired olfactory discrimination learning and decreased olfactory sensitivity in aged C57Bl/6 mice
- (2007) Roseanne C. Patel et al. NEUROBIOLOGY OF AGING
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now