SARS-CoV-2 vaccines in advanced clinical trials: Where do we stand?

Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

(2020) Aiping Wu et al.   Cell Host & Microbe

A new coronavirus associated with human respiratory disease in China

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First Case of 2019 Novel Coronavirus in the United States

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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

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The promise of mRNA vaccines: a biotech and industrial perspective

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The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application

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Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

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New Measures for the Coronavirus Disease 2019 Response: A Lesson From the Wenzhou Experience

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Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients

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The presence of SARS‐CoV‐2 RNA in the feces of COVID‐19 patients

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An 81 nucleotide deletion in SARS-CoV-2 ORF7a identified from sentinel surveillance in Arizona (Jan-Mar 2020)

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Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

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Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study

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Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

(2020) Dora Pinto et al.   NATURE

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

(2020) Irani Thevarajan et al.   NATURE MEDICINE

Antibody responses to SARS-CoV-2 in patients with COVID-19

(2020) Quan-Xin Long et al.   NATURE MEDICINE

Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1

(2020) Neeltje van Doremalen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

(2020) Yan Wu et al.   SCIENCE

Reducing transmission of SARS-CoV-2

(2020) Kimberly A. Prather et al.   SCIENCE

Development of an inactivated vaccine candidate for SARS-CoV-2

(2020) Qiang Gao et al.   SCIENCE

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period

(2020) Stephen M. Kissler et al.   SCIENCE

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

(2020) Jingyou Yu et al.   SCIENCE

Immunogenicity of a DNA vaccine candidate for COVID-19

(2020) Trevor R. F. Smith et al.   Nature Communications

Factors Which Contribute to the Immunogenicity of Non-replicating Adenoviral Vectored Vaccines

(2020) Lynda Coughlan   Frontiers in Immunology

A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques

(2020) Neeltje van Doremalen et al.   Science Advances

SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis

(2020) Elio Issa et al.   mSystems

Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2

(2020) Hui Wang et al.   CELL

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

(2020) Bette Korber et al.   CELL

On the evolutionary epidemiology of SARS-CoV-2

(2020) Troy Day et al.   CURRENT BIOLOGY

Distinct Early Serological Signatures Track with SARS-CoV-2 Survival

(2020) Caroline Atyeo et al.   IMMUNITY

Airborne Transmission of SARS-CoV-2

(2020) Michael Klompas et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes

(2020) Shengli Xia et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial

(2020) Feng-Cai Zhu et al.   LANCET

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

(2020) Pedro M Folegatti et al.   LANCET

Single-shot live-attenuated chikungunya vaccine in healthy adults: a phase 1, randomised controlled trial

(2020) Nina Wressnigg et al.   LANCET INFECTIOUS DISEASES

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

(2020) Noe B. Mercado et al.   NATURE

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

(2020) Kizzmekia S. Corbett et al.   NATURE

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

(2020) Neeltje van Doremalen et al.   NATURE

Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults

(2020) Mark J. Mulligan et al.   NATURE

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

(2020) Nina Le Bert et al.   NATURE

Convergent antibody responses to SARS-CoV-2 in convalescent individuals

(2020) Davide F. Robbiani et al.   NATURE

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

(2020) Lihong Liu et al.   NATURE

Potently neutralizing and protective human antibodies against SARS-CoV-2

(2020) Seth J. Zost et al.   NATURE

Next-generation vaccine platforms for COVID-19

(2020) Debby van Riel et al.   NATURE MATERIALS

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

(2020) Kizzmekia S. Corbett et al.   NEW ENGLAND JOURNAL OF MEDICINE

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

(2020) Lisa A. Jackson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Serology assays to manage COVID-19

(2020) Florian Krammer et al.   SCIENCE

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

(2020) Philip J. M. Brouwer et al.   SCIENCE

Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice

(2020) Paul F. McKay et al.   Nature Communications

A Snapshot of the Global Race for Vaccines Targeting SARS-CoV-2 and the COVID-19 Pandemic

(2020) Colin D. Funk et al.   Frontiers in Pharmacology

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

(2020) Simon P. Graham et al.   npj Vaccines

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

(2020) Daniela Weiskopf et al.   Science Immunology

TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

(2020) Dorothea Bestle et al.   Life Science Alliance

Probable Evidence of Fecal Aerosol Transmission of SARS-CoV-2 in a High-Rise Building

(2020) Min Kang et al.   ANNALS OF INTERNAL MEDICINE

Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

(2020) Ahmad Abu Turab Naqvi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

(2020) Ahmed O. Hassan et al.   CELL

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology

(2020) Luca Piccoli et al.   CELL

Vaccines for COVID‐19

(2020) J. S. Tregoning et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Molecular conservation and differential mutation on ORF3a gene in Indian SARS-CoV2 genomes

(2020) Sk. Sarif Hassan et al.   GENOMICS

COVID-19 and mRNA Vaccines—First Large Test for a New Approach

(2020) Jennifer Abbasi   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Herd Immunity and Implications for SARS-CoV-2 Control

(2020) Saad B. Omer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack Rate

(2020) Amin Addetia et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia

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SARS-CoV-2 vaccines in development

(2020) Florian Krammer   NATURE

ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection

(2020) Asmaa Hachim et al.   NATURE IMMUNOLOGY

Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters

(2020) Lisa H. Tostanoski et al.   NATURE MEDICINE

An inflammatory cytokine signature predicts COVID-19 severity and survival

(2020) Diane Marie Del Valle et al.   NATURE MEDICINE

Humoral Immune Response to SARS-CoV-2 in Iceland

(2020) Daniel F. Gudbjartsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates

(2020) Edward E. Walsh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

(2020) Evan J. Anderson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine

(2020) Cheryl Keech et al.   NEW ENGLAND JOURNAL OF MEDICINE

Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype

(2020) Jennifer R. Habel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

(2020) Sandhya Bangaru et al.   SCIENCE

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

(2020) M. Alejandra Tortorici et al.   SCIENCE

NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge

(2020) Mimi Guebre-Xabier et al.   VACCINE

Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneity

(2020) M. Rafiul Islam et al.   Scientific Reports

Virology, transmission, and pathogenesis of SARS-CoV-2

(2020) Muge Cevik et al.   BMJ-British Medical Journal

Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: A living systematic review and meta-analysis

(2020) Diana Buitrago-Garcia et al.   PLOS MEDICINE

Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic

(2020) Chase W Nelson et al.   eLife

SARS-CoV-2 Proteome Microarray for Mapping COVID-19 Antibody Interactions at Amino Acid Resolution

(2020) Hongye Wang et al.   ACS Central Science

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

(2020) Maheshi N Ramasamy et al.   LANCET

Towards an accurate and systematic characterisation of persistently asymptomatic infection with SARS-CoV-2

(2020) Eric A Meyerowitz et al.   LANCET INFECTIOUS DISEASES

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

(2020) Katie J. Ewer et al.   NATURE MEDICINE

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

(2020) Lindsey R. Baden et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

(2020) Fernando P. Polack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

(2020) Mads Delbo Larsen et al.   SCIENCE

COVID-19 transmission—up in the air

(2020) The Lancet Respiratory Medicine   Lancet Respiratory Medicine

Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial

(2020) Yanjun Zhang et al.   LANCET INFECTIOUS DISEASES

mRNA as a Transformative Technology for Vaccine Development to Control Infectious Diseases

(2019) Giulietta Maruggi et al.   MOLECULAR THERAPY

Intradermal SynCon® Ebola GP DNA Vaccine is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers

(2019) Pablo Tebas et al.   JOURNAL OF INFECTIOUS DISEASES

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

(2019) Alexandra C. Walls et al.   CELL

Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC

(2019) Kam-Leung Siu et al.   FASEB JOURNAL

Coronavirus envelope protein: current knowledge

(2019) Dewald Schoeman et al.   Virology Journal

Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial

(2019) Kayvon Modjarrad et al.   LANCET INFECTIOUS DISEASES

Virus-Like Particles as an Instrument of Vaccine Production

(2019) B. V. Syomin et al.   MOLECULAR BIOLOGY

Structural basis for human coronavirus attachment to sialic acid receptors

(2019) M. Alejandra Tortorici et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus

(2019) Chean Yeah Yong et al.   Frontiers in Microbiology

Regulatory aspects of quality and safety for live recombinant viral vaccines against infectious diseases in Japan

(2019) Akira Sakurai et al.   VACCINE

Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials

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mRNA vaccines — a new era in vaccinology

(2018) Norbert Pardi et al.   NATURE REVIEWS DRUG DISCOVERY

Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis

(2018) Carlos Castaño-Rodriguez et al.   mBio

Noninvasive vaccination against infectious diseases

(2018) Zhichao Zheng et al.   Human Vaccines & Immunotherapeutics

SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death

(2018) Yuan Yue et al.   Cell Death & Disease

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

(2018) Robert N. Kirchdoerfer et al.   Scientific Reports

New Vaccine Technologies to Combat Outbreak Situations

(2018) Susanne Rauch et al.   Frontiers in Immunology

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

(2017) Norbert Pardi et al.   NATURE

Chimpanzee Adenovirus Vector Ebola Vaccine

(2017) Julie E. Ledgerwood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion

(2017) Alexandra C. Walls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

(2017) Jesper Pallesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increasing the breadth and potency of response to the seasonal influenza virus vaccine by immune complex immunization

(2017) Jad Maamary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity

(2017) Taia T. Wang et al.   SCIENCE

Yellow fever live attenuated vaccine: A very successful live attenuated vaccine but still we have problems controlling the disease

(2017) Alan D.T. Barrett   VACCINE

Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines

(2017) Troy C. Sutton et al.   npj Vaccines

Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection

(2016) Carole J. Henry Dunand et al.   Cell Host & Microbe

Cutaneous and Visceral Chronic Granulomatous Disease Triggered by a Rubella Virus Vaccine Strain in Children With Primary Immunodeficiencies: Table 1.

(2016) Bénédicte Neven et al.   CLINICAL INFECTIOUS DISEASES

Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection

(2016) David J. DiLillo et al.   JOURNAL OF CLINICAL INVESTIGATION

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

(2016) Alexandra C. Walls et al.   NATURE

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

(2016) Katie Ewer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact

(2016) Paul E. Leon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy

(2016) Alexandra Walls et al.   PROTEIN SCIENCE

Adverse events following immunization in patients with primary immunodeficiencies

(2016) Juan David Sarmiento et al.   VACCINE

Engineering virus-like particles as vaccine platforms

(2016) Kathryn M Frietze et al.   Current Opinion in Virology

Ebola vaccines in clinical trial: The promising candidates

(2016) Yuxiao Wang et al.   Human Vaccines & Immunotherapeutics

Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus

(2016) Anurodh Shankar Agrawal et al.   Human Vaccines & Immunotherapeutics

Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules

(2016) Isabelle Legastelois et al.   Human Vaccines & Immunotherapeutics

Flucelvax (Optaflu) for seasonal influenza

(2015) Ilaria Manini et al.   Expert Review of Vaccines

Severe Acute Respiratory Syndrome Coronaviruses with Mutations in the E Protein Are Attenuated and Promising Vaccine Candidates

(2015) Jose A. Regla-Nava et al.   JOURNAL OF VIROLOGY

Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial

(2015) Katrin Ramsauer et al.   LANCET INFECTIOUS DISEASES

Live attenuated vaccines: Historical successes and current challenges

(2015) Philip D. Minor   VIROLOGY

Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

(2015) Jean Kaoru Millet et al.   VIRUS RESEARCH

Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies

(2015) Shujing Wang et al.   Protein & Cell

Accessory proteins of SARS-CoV and other coronaviruses

(2014) Ding Xiang Liu et al.   ANTIVIRAL RESEARCH

The SARS coronavirus nucleocapsid protein – Forms and functions

(2014) Chung-ke Chang et al.   ANTIVIRAL RESEARCH

Prior Immunization with Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus (SARS-CoV) Nucleocapsid Protein Causes Severe Pneumonia in Mice Infected with SARS-CoV

(2014) F. Yasui et al.   JOURNAL OF IMMUNOLOGY

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection

(2014) V. V. A. Mallajosyula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

History of vaccination

(2014) S. Plotkin   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Coronavirus Nucleocapsid Is a Multifunctional Protein

(2014) Ruth McBride et al.   Viruses-Basel

Pre-existing immunity against Ad vectors

(2014) Hugues Fausther-Bovendo et al.   Human Vaccines & Immunotherapeutics

Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis

(2014) Jose L. Nieto-Torres et al.   PLoS Pathogens

Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development

(2013) William A Rodríguez-Limas et al.   CURRENT OPINION IN BIOTECHNOLOGY

Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate

(2013) F. Almazan et al.   mBio

Viral vaccines: past successes and future challenges

(2013) Rafi Ahmed et al.   Current Opinion in Virology

Recombinant vaccines and the development of new vaccine strategies

(2012) I.P. Nascimento et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

(2012) R. Hai et al.   JOURNAL OF VIROLOGY

Correction: Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

(2012) Chien-Te Tseng et al.   PLoS One

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

(2012) N. Pica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids

(2012) Carmina Verdiá-Báguena et al.   VIROLOGY

Ready, Set, Fuse! The Coronavirus Spike Protein and Acquisition of Fusion Competence

(2012) Taylor Heald-Sargent et al.   Viruses-Basel

Adenoviral Vector Immunity: Its Implications and Circumvention Strategies

(2011) Yadvinder S. Ahi et al.   CURRENT GENE THERAPY

A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

(2011) M. Bolles et al.   JOURNAL OF VIROLOGY

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials

(2011) Julie E Ledgerwood et al.   LANCET INFECTIOUS DISEASES

Immunological mechanisms of vaccination

(2011) Bali Pulendran et al.   NATURE IMMUNOLOGY

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

(2011) D. Corti et al.   SCIENCE

Subcellular location and topology of severe acute respiratory syndrome coronavirus envelope protein

(2011) Jose L. Nieto-Torres et al.   VIROLOGY

Virus-like particles in vaccine development

(2010) António Roldão et al.   Expert Review of Vaccines

Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronaviruses 229E and OC43

(2010) Hyun-Kyoung Lee et al.   Journal of Veterinary Science

A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults

(2010) J.E. Ledgerwood et al.   VACCINE

Phase 1 clinical trials of the safety and immunogenicity of adjuvanted plasmid DNA vaccines encoding influenza A virus H5 hemagglutinin

(2010) Larry R. Smith et al.   VACCINE

Differential Stepwise Evolution of SARS Coronavirus Functional Proteins in Different Host Species

(2009) Xianchun Tang et al.   BMC EVOLUTIONARY BIOLOGY

The Open Reading Frame 3a Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Promotes Membrane Rearrangement and Cell Death

(2009) E. C. Freundt et al.   JOURNAL OF VIROLOGY

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

(2009) Jianhua Sui et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

DNA vaccination protects against an influenza challenge in a double-blind randomised placebo-controlled phase 1b clinical trial

(2009) Suzanne Jones et al.   VACCINE

FluBlok, a recombinant hemagglutinin influenza vaccine

(2008) Manon M.J. Cox et al.   Influenza and Other Respiratory Viruses

Severe acute respiratory syndrome coronavirus 3a protein activates the mitochondrial death pathway through p38 MAP kinase activation

(2008) K. Padhan et al.   JOURNAL OF GENERAL VIROLOGY

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Virus-Like Particles of SARS-Like Coronavirus Formed by Membrane Proteins from Different Origins Demonstrate Stimulating Activity in Human Dendritic Cells

(2008) Bingke Bai et al.   PLoS One

Dissection and identification of regions required to form pseudoparticles by the interaction between the nucleocapsid (N) and membrane (M) proteins of SARS coronavirus

(2008) Seisuke Hatakeyama et al.   VIROLOGY

SARS coronavirus accessory proteins

(2007) Krishna Narayanan et al.   VIRUS RESEARCH