Virus-like particles in vaccine development

Low pH-Triggered Model Drug Molecule Release from Virus-Like Particles

(2010) Noriko Ohtake et al.   CHEMBIOCHEM

Influenza virus-like particles as an antigen-carrier platform for the ESAT-6 epitope of Mycobacterium tuberculosis

(2010) Florian Krammer et al.   JOURNAL OF VIROLOGICAL METHODS

Assembly and Biological and Immunological Properties of Newcastle Disease Virus-Like Particles

(2010) L. W. McGinnes et al.   JOURNAL OF VIROLOGY

Trichoplusia ni cells (High FiveTM) are highly efficient for the production of influenza A virus-like particles: a comparison of two insect cell lines as production platforms for influenza vaccines

(2010) Florian Krammer et al.   MOLECULAR BIOTECHNOLOGY

Hepatitis B vaccines: Protective efficacy and therapeutic potential

(2010) M.-L. Michel et al.   PATHOLOGIE BIOLOGIE

Mammalian Expression of Virus-Like Particles for Advanced Mimicry of Authentic Influenza Virus

(2010) Chia-Ying Wu et al.   PLoS One

Virus-Like Particle Vaccine Protects against 2009 H1N1 Pandemic Influenza Virus in Mice

(2010) Fu-Shi Quan et al.   PLoS One

Expression and self-assembly of virus-like particles of infectious hypodermal and hematopoietic necrosis virus in Escherichia coli

(2009) Luhong Hou et al.   ARCHIVES OF VIROLOGY

Expression and characterization of HPV-16 L1 capsid protein in Pichia pastoris

(2009) Silvia Boschi Bazan et al.   ARCHIVES OF VIROLOGY

N/P Ratio Significantly Influences the Transfection Efficiency and Cytotoxicity of a Polyethylenimine/Chitosan/DNA Complex

(2009) Qing-Qing Zhao et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Advances in on-line monitoring and control of mammalian cell cultures: Supporting the PAT initiative

(2009) A.P. Teixeira et al.   BIOTECHNOLOGY ADVANCES

A DNA replicon system for rapid high-level production of virus-like particles in plants

(2009) Zhong Huang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Cell density effect in the baculovirus-insect cells system: A quantitative analysis of energetic metabolism

(2009) Vicente Bernal et al.   BIOTECHNOLOGY AND BIOENGINEERING

Swine-origin pandemic H1N1 influenza virus-like particles produced in insect cells induce hemagglutination inhibiting antibodies in BALB/c mice

(2009) Florian Krammer et al.   Biotechnology Journal

Optimization of chimeric HIV-1 virus-like particle production in a baculovirus-insect cell expression system

(2009) Sirika Pillay et al.   BIOTECHNOLOGY PROGRESS

Purification of recombinant baculoviruses for gene therapy using membrane processes

(2009) T Vicente et al.   GENE THERAPY

Newcastle Disease Virus-Like Particles Containing Respiratory Syncytial Virus G Protein Induced Protection in BALB/c Mice, with No Evidence of Immunopathology

(2009) M. R. Murawski et al.   JOURNAL OF VIROLOGY

A review of human carcinogens—Part B: biological agents

(2009) Véronique Bouvard et al.   LANCET ONCOLOGY

Improving baculovirus production at high cell density through manipulation of energy metabolism

(2009) Nuno Carinhas et al.   METABOLIC ENGINEERING

Induction of Long-Term Protective Immune Responses by Influenza H5N1 Virus-Like Particles

(2009) Sang-Moo Kang et al.   PLoS One

Skin Electroporation: Effects on Transgene Expression, DNA Persistence and Local Tissue Environment

(2009) Anna-Karin Roos et al.   PLoS One

Monitoring virus-like particle and viral protein production by intact cell MALDI-TOF mass spectrometry

(2009) Catarina F. Franco et al.   TALANTA

Display of neutralizing epitopes of Canine parvovirus and a T-cell epitope of the fusion protein of Canine distemper virus on chimeric tymovirus-like particles and its use as a vaccine candidate both against Canine parvo and Canine distemper

(2009) Dev Chandran et al.   VACCINE

Refining HPV 16 L1 purification from E. coli: Reducing endotoxin contaminations and their impact on immunogenicity

(2009) Lysann Schädlich et al.   VACCINE

M2e-based universal influenza A vaccine

(2009) Walter Fiers et al.   VACCINE

An HPV 16 L1-based chimeric human papilloma virus-like particles containing a string of epitopes produced in plants is able to elicit humoral and cytotoxic T-cell activity in mice

(2009) Georgina De la Rosa et al.   Virology Journal

Influenza vaccines based on virus-like particles

(2009) Sang-Moo Kang et al.   VIRUS RESEARCH

Characterization of virus-like particle assembly for DNA delivery using asymmetrical flow field-flow fractionation and light scattering

(2008) Andrzej Citkowicz et al.   ANALYTICAL BIOCHEMISTRY

Achievement of avian influenza virus-like particles that could be used as a subunit vaccine against low-pathogenic avian influenza strains in ducks

(2008) Anne Prel et al.   AVIAN PATHOLOGY

Virus-like Particles as Quantitative Probes of Membrane Protein Interactions†

(2008) Sharon Willis et al.   BIOCHEMISTRY

The coming of age of virus-like particle vaccines

(2008) Gary T. Jennings et al.   BIOLOGICAL CHEMISTRY

In situ 2D fluorometry and chemometric monitoring of mammalian cell cultures

(2008) Ana P. Teixeira et al.   BIOTECHNOLOGY AND BIOENGINEERING

Towards purification of adenoviral vectors based on membrane technology

(2008) Cristina Peixoto et al.   BIOTECHNOLOGY PROGRESS

Differential protein expression following low temperature culture of suspension CHO-K1 cells

(2008) Niraj Kumar et al.   BMC BIOTECHNOLOGY

Comparison of different commercially available cationic liposome–DNA lipoplexes: Parameters influencing toxicity and transfection efficiency

(2008) A. Masotti et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis

(2008) Gunther Spohn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Presentation of functional foreign peptides on the surface of SV40 virus-like particles

(2008) Ryou-u Takahashi et al.   JOURNAL OF BIOTECHNOLOGY

Sodium dodecyl sulfate-capillary gel electrophoresis analysis of rotavirus-like particles

(2008) Maria Candida M. Mellado et al.   JOURNAL OF CHROMATOGRAPHY A

Purification of recombinant rotavirus VP7 glycoprotein for the study of in vitro rotavirus-like particles assembly

(2008) M MELLADO et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Self-Assembly of the Recombinant Capsid Protein of a Swine Norovirus into Virus-Like Particles and Evaluation of Monoclonal Antibodies Cross-Reactive with a Human Strain from Genogroup II

(2008) H. Almanza et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Heparin binding induces conformational changes in Adeno-associated virus serotype 2

(2008) Hazel C. Levy et al.   JOURNAL OF STRUCTURAL BIOLOGY

Recombinant hepatitis B virus core particles: Association, dissociation and encapsidation of green fluorescent protein

(2008) Khai Wooi Lee et al.   JOURNAL OF VIROLOGICAL METHODS

Incorporation of Membrane-Anchored Flagellin into Influenza Virus-Like Particles Enhances the Breadth of Immune Responses

(2008) B.-Z. Wang et al.   JOURNAL OF VIROLOGY

Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study

(2008) Alain C Tissot et al.   LANCET

Transient Transfection Factors for High-Level Recombinant Protein Production in Suspension Cultured Mammalian Cells

(2008) Chaoting Liu et al.   MOLECULAR BIOTECHNOLOGY

Influenza virus-like particles produced by transient expression inNicotiana benthamianainduce a protective immune response against a lethal viral challenge in mice

(2008) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL

Cross-Clade Protective Immune Responses to Influenza Viruses with H5N1 HA and NA Elicited by an Influenza Virus-Like Particle

(2008) Rick A. Bright et al.   PLoS One

A Vaccine against Nicotine for Smoking Cessation: A Randomized Controlled Trial

(2008) Jacques Cornuz et al.   PLoS One

Enhanced intracellular accumulation of recombinant HBsAg in CHO cells by dimethyl sulfoxide

(2008) Zheyong Ma et al.   PROCESS BIOCHEMISTRY

Optimum conditions for production and purification of human papillomavirus type 16 L1 protein from Saccharomyces cerevisiae

(2008) Min-A Park et al.   PROTEIN EXPRESSION AND PURIFICATION

H5N1 VLP vaccine induced protection in ferrets against lethal challenge with highly pathogenic H5N1 influenza viruses

(2008) Kutubuddin Mahmood et al.   VACCINE

An update of prophylactic human papillomavirus L1 virus-like particle vaccine clinical trial results

(2008) John T. Schiller et al.   VACCINE

Influenza-pseudotyped Gag virus-like particle vaccines provide broad protection against highly pathogenic avian influenza challenge

(2008) Joel R. Haynes et al.   VACCINE

Protection against lethal challenge by Ebola virus-like particles produced in insect cells

(2008) Yuliang Sun et al.   VIROLOGY

Rift Valley fever virus structural proteins: expression, characterization and assembly of recombinant proteins

(2008) Li Liu et al.   Virology Journal

Escherichia coli-based cell-free synthesis of virus-like particles

(2007) Bradley C. Bundy et al.   BIOTECHNOLOGY AND BIOENGINEERING

Stochastic simulation of protein expression in the baculovirus/insect cells system

(2007) António Roldão et al.   COMPUTERS & CHEMICAL ENGINEERING

Anion-exchange membrane chromatography for purification of rotavirus-like particles

(2007) Tiago Vicente et al.   JOURNAL OF MEMBRANE SCIENCE

Production of rotavirus-like particles in Spodoptera frugiperda larvae

(2007) P. Molinari et al.   JOURNAL OF VIROLOGICAL METHODS

Production of Recombinant Adeno-Associated Viral Vectors Using a Baculovirus/Insect Cell Suspension Culture System: From Shake Flasks to a 20-L Bioreactor

(2005) Jamal Meghrous et al.   BIOTECHNOLOGY PROGRESS