Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
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Title
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 35, Pages E7348-E7357
Publisher
Proceedings of the National Academy of Sciences
Online
2017-08-15
DOI
10.1073/pnas.1707304114
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Related references
Note: Only part of the references are listed.- Middle East Respiratory Syndrome
- (2017) Yaseen M. Arabi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Sequential activation of the three protomers in the Moloney murine leukemia virus Env
- (2017) Mathilda Sjöberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding
- (2016) Miao Gui et al. CELL RESEARCH
- Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer
- (2016) Alexandra C. Walls et al. NATURE
- Pre-fusion structure of a human coronavirus spike protein
- (2016) Robert N. Kirchdoerfer et al. NATURE
- A roadmap for MERS-CoV research and product development: report from a World Health Organization consultation
- (2016) Kayvon Modjarrad et al. NATURE MEDICINE
- Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy
- (2016) Alexandra C Walls et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules
- (2016) Haim Ashkenazy et al. NUCLEIC ACIDS RESEARCH
- Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer
- (2016) J. H. Lee et al. SCIENCE
- Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
- (2016) R. Kong et al. SCIENCE
- Vaccines against respiratory syncytial virus: The time has finally come
- (2016) Barney S. Graham VACCINE
- Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir
- (2016) Hamzah A. Mohd et al. Virology Journal
- Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability
- (2016) Leopold Kong et al. Nature Communications
- Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy
- (2016) Alexandra C Walls et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure, Function, and Evolution of Coronavirus Spike Proteins
- (2016) Fang Li Annual Review of Virology
- A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein
- (2015) Yan Li et al. CELL RESEARCH
- Human Coronavirus HKU1 Spike Protein UsesO-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme
- (2015) Xingchuan Huang et al. JOURNAL OF VIROLOGY
- Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection
- (2015) Hadi M Yassine et al. NATURE MEDICINE
- Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement
- (2015) Frank DiMaio et al. NATURE METHODS
- EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
- (2015) Benjamin A Barad et al. NATURE METHODS
- X-ray structure determination using low-resolution electron microscopy maps for molecular replacement
- (2015) Ryan N Jackson et al. Nature Protocols
- Privateer: software for the conformational validation of carbohydrate structures
- (2015) Jon Agirre et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- 2014 MERS-CoV Outbreak in Jeddah — A Link to Health Care Facilities
- (2015) Ikwo K. Oboho et al. NEW ENGLAND JOURNAL OF MEDICINE
- Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
- (2015) Davide Corti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen
- (2015) A. Impagliazzo et al. SCIENCE
- Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells
- (2015) Scott F. Rusin et al. Science Signaling
- Receptor-binding domain-based subunit vaccines against MERS-CoV
- (2015) Naru Zhang et al. VIRUS RESEARCH
- Evaluation of candidate vaccine approaches for MERS-CoV
- (2015) Lingshu Wang et al. Nature Communications
- A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism
- (2015) Anders Krarup et al. Nature Communications
- Privateer: software for the conformational validation of carbohydrate structures
- (2015) Jon Agirre et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells
- (2015) Scott F. Rusin et al. Science Signaling
- Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
- (2014) Xiangguo Qiu et al. NATURE
- Structure and immune recognition of trimeric pre-fusion HIV-1 Env
- (2014) Marie Pancera et al. NATURE
- Evidence for Camel-to-Human Transmission of MERS Coronavirus
- (2014) Esam I. Azhar et al. NEW ENGLAND JOURNAL OF MEDICINE
- Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein
- (2014) Jean Kaoru Millet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
- (2014) X.-C. Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
- (2014) J. B. Munro et al. SCIENCE
- Potent Neutralization of MERS-CoV by Human Neutralizing Monoclonal Antibodies to the Viral Spike Glycoprotein
- (2014) L. Jiang et al. Science Translational Medicine
- How good are my data and what is the resolution?
- (2013) Philip R. Evans et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4
- (2013) Nianshuang Wang et al. CELL RESEARCH
- Middle East Respiratory Syndrome Coronavirus Infection Mediated by the Transmembrane Serine Protease TMPRSS2
- (2013) Kazuya Shirato et al. JOURNAL OF VIROLOGY
- The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies
- (2013) S. Gierer et al. JOURNAL OF VIROLOGY
- Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
- (2013) Guangwen Lu et al. NATURE
- Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
- (2013) V. Stalin Raj et al. NATURE
- Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM
- (2013) Xueming Li et al. NATURE METHODS
- Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
- (2013) T. Scobey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus
- (2013) J. S. McLellan et al. SCIENCE
- Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer
- (2013) J.-P. Julien et al. SCIENCE
- Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
- (2013) D. Lyumkis et al. SCIENCE
- Collaboration gets the most out of software
- (2013) Andrew Morin et al. eLife
- Crystal Structure of Bovine Coronavirus Spike Protein Lectin Domain
- (2012) Guiqing Peng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
- (2012) Ali M. Zaki et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genomic Characterization of a Newly Discovered Coronavirus Associated with Acute Respiratory Distress Syndrome in Humans
- (2012) S. van Boheemen et al. mBio
- iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM
- (2011) T. Geoff G. Battye et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Improved molecular replacement by density- and energy-guided protein structure optimization
- (2011) Frank DiMaio et al. NATURE
- Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor
- (2011) G. Peng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Coronavirus Diversity, Phylogeny and Interspecies Jumping
- (2009) Patrick C. Y. Woo et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Refinement of Protein Structures into Low-Resolution Density Maps Using Rosetta
- (2009) Frank DiMaio et al. JOURNAL OF MOLECULAR BIOLOGY
- Appion: An integrated, database-driven pipeline to facilitate EM image processing
- (2009) Gabriel C. Lander et al. JOURNAL OF STRUCTURAL BIOLOGY
- DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy
- (2009) N.R. Voss et al. JOURNAL OF STRUCTURAL BIOLOGY
- Two-Step Conformational Changes in a Coronavirus Envelope Glycoprotein Mediated by Receptor Binding and Proteolysis
- (2009) S. Matsuyama et al. JOURNAL OF VIROLOGY
- Antibody Recognition of a Highly Conserved Influenza Virus Epitope
- (2009) D. C. Ekiert et al. SCIENCE
- A single amino acid substitution in the S1 and S2 Spike protein domains determines the neutralization escape phenotype of SARS-CoV
- (2008) Yu-ya Mitsuki et al. MICROBES AND INFECTION
- Broadening of Neutralization Activity to Directly Block a Dominant Antibody-Driven SARS-Coronavirus Evolution Pathway
- (2008) Jianhua Sui et al. PLoS Pathogens
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