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Title
The NLRP3 Inflammasome and Its Role in T1DM
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-08-27
DOI
10.3389/fimmu.2020.01595
References
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- (2020) Claude A. Piantadosi FREE RADICAL BIOLOGY AND MEDICINE
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- (2019) Klara Kubelkova et al. Frontiers in Cellular and Infection Microbiology
- Polymorphisms in NLRP1 Gene Are Associated with Type 1 Diabetes
- (2019) Xiaoxiao Sun et al. Journal of Diabetes Research
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- (2019) Evanthia Tourkochristou et al. WORLD JOURNAL OF GASTROENTEROLOGY
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- (2019) Susanna Esposito et al. Frontiers in Endocrinology
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- Modulatory Mechanisms of the NLRP3 Inflammasomes in Diabetes
- (2019) Sujuan Ding et al. Biomolecules
- Autophagy and Inflammation
- (2018) Yu Matsuzawa-Ishimoto et al. Annual Review of Immunology
- The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
- (2018) Charles L. Evavold et al. IMMUNITY
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- (2018) Maria G. Daskalaki et al. JOURNAL OF CELLULAR PHYSIOLOGY
- COPs and POPs Patrol Inflammasome Activation
- (2018) Mohanalaxmi Indramohan et al. JOURNAL OF MOLECULAR BIOLOGY
- Type 1 diabetes
- (2018) Linda A DiMeglio et al. LANCET
- Pattern recognition receptors in fungal immunity
- (2018) Emmanuel C. Patin et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- NLRP3 inflammasome is expressed and regulated in human islets
- (2018) Fanny Lebreton et al. Cell Death & Disease
- Incidence and Trend of Type 1 Diabetes and the Underlying Environmental Determinants
- (2018) Ying Xia et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- The role of mitochondria in NLRP3 inflammasome activation
- (2018) Qiuyun Liu et al. MOLECULAR IMMUNOLOGY
- Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion
- (2018) Mercedes Monteleone et al. Cell Reports
- Role of the NLRP3 inflammasome in cancer
- (2018) Maryam Moossavi et al. Molecular Cancer
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- (2018) Nan Song et al. Frontiers in Immunology
- The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease
- (2018) Shuo Wang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Mechanisms governing inflammasome activation, assembly and pyroptosis induction
- (2017) Sannula Kesavardhana et al. INTERNATIONAL IMMUNOLOGY
- NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
- (2017) Zhen Qiu et al. Oxidative Medicine and Cellular Longevity
- Pyrin-only protein 2 limits inflammation but improves protection against bacteria
- (2017) Sivakumar Periasamy et al. Nature Communications
- Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model
- (2017) Daniela Carlos et al. Frontiers in Immunology
- Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance
- (2016) Je-Wook Yu et al. ARCHIVES OF PHARMACAL RESEARCH
- Beyond Genetics: What Causes Type 1 Diabetes
- (2016) Zhen Wang et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria
- (2016) Christina J. Groß et al. IMMUNITY
- The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation
- (2016) Deepika Sharma et al. JOURNAL OF CELL BIOLOGY
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells
- (2016) G. Arbore et al. SCIENCE
- Innate inflammation in type 1 diabetes
- (2016) Susanne M. Cabrera et al. Translational Research
- Neutrophils in type 1 diabetes
- (2016) Juan Huang et al. Journal of Diabetes Investigation
- Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages
- (2015) Sung-Soo Jung et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Innate Immune Pattern Recognition: A Cell Biological Perspective
- (2015) Sky W. Brubaker et al. Annual Review of Immunology
- How apoptotic β-cells direct immune response to tolerance or to autoimmune diabetes: a review
- (2015) Marta Vives-Pi et al. APOPTOSIS
- Molecular mechanisms regulating NLRP3 inflammasome activation
- (2015) Eun-Kyeong Jo et al. Cellular & Molecular Immunology
- A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice
- (2015) Ronald G. Gill et al. DIABETES
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- (2015) Sebastian Rühl et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets
- (2015) Changyun Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lysosomes Integrate Metabolic-Inflammatory Cross-talk in Primary Macrophage Inflammasome Activation
- (2014) Kassandra Weber et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Macrophages sense and kill bacteria through carbon monoxide–dependent inflammasome activation
- (2014) Barbara Wegiel et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2013) Kairui Mao et al. CELL RESEARCH
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- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
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- (2013) T. Fernandes-Alnemri et al. JOURNAL OF IMMUNOLOGY
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- (2013) Hiutung Chu et al. NATURE IMMUNOLOGY
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- (2012) Christine Juliana et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Mélanie Bruchard et al. NATURE MEDICINE
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- (2012) Ellen K. Grishman et al. PEDIATRIC RESEARCH
- Activated Human CD4+CD45RO+ Memory T-Cells Indirectly Inhibit NLRP3 Inflammasome Activation through Downregulation of P2X7R Signalling
- (2012) Vanessa Beynon et al. PLoS One
- In vivo diabetogenic action of CD4+ T lymphocytes requires Fas expression and is independent of IL-1 and IL-18
- (2011) Li Wen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
- (2011) Greta Guarda et al. IMMUNITY
- Is caspase 1 central to activation of interleukin-1?
- (2011) Miriam Wittmann et al. JOINT BONE SPINE
- Preliminary studies related to anti-interleukin-1β therapy in children with newly diagnosed type 1 diabetes
- (2011) Kathryn M. Sumpter et al. PEDIATRIC DIABETES
- The Nlrp3 inflammasome: contributions to intestinal homeostasis
- (2011) Md. Hasan Zaki et al. TRENDS IN IMMUNOLOGY
- Two SNPs inNLRP3gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil
- (2010) A. Pontillo et al. AUTOIMMUNITY
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Signaling by ROS drives inflammasome activation
- (2010) Fabio Martinon EUROPEAN JOURNAL OF IMMUNOLOGY
- The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
- (2010) Md. Hasan Zaki et al. IMMUNITY
- NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
- (2010) Simon A. Hirota et al. INFLAMMATORY BOWEL DISEASES
- Nlrp3: An immune sensor of cellular stress and infection
- (2010) Mohamed Lamkanfi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Sodium Overload and Water Influx Activate the NALP3 Inflammasome
- (2010) Christine Schorn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- IL-1β Processing in Host Defense: Beyond the Inflammasomes
- (2010) Mihai G. Netea et al. PLoS Pathogens
- A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses
- (2009) Guangxun Meng et al. IMMUNITY
- IL-1β receptor blockade protects islets against pro-inflammatory cytokine induced necrosis and apoptosis
- (2009) Alice Schwarznau et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Inflammasomes: too big to miss
- (2009) Andrea Stutz et al. JOURNAL OF CLINICAL INVESTIGATION
- Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells
- (2009) E. M. Bradshaw et al. JOURNAL OF IMMUNOLOGY
- Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
- (2009) Olaf Gross et al. NATURE
- Thioredoxin-interacting protein links oxidative stress to inflammasome activation
- (2009) Rongbin Zhou et al. NATURE IMMUNOLOGY
- Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal
- (2009) Catherine Dostert et al. PLoS One
- Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
- (2009) Fiona A. Sharp et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Thioredoxin-Interacting Protein: A Critical Link Between Glucose Toxicity and -Cell Apoptosis
- (2008) J. Chen et al. DIABETES
- The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity
- (2008) Luigi Franchi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
- (2008) Daniel A. Muruve et al. NATURE
- Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
- (2008) Stephanie C. Eisenbarth et al. NATURE
- Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
- (2008) Tatsuya Saitoh et al. NATURE
- Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
- (2008) Felix Meissner et al. NATURE IMMUNOLOGY
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
- The Nalp3 inflammasome is essential for the development of silicosis
- (2008) Suzanne L. Cassel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
- (2008) C. Dostert et al. SCIENCE
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