Involvement of TGF-β and Autophagy Pathways in Pathogenesis of Diabetes: A Comprehensive Review on Biological and Pharmacological Insights
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Involvement of TGF-β and Autophagy Pathways in Pathogenesis of Diabetes: A Comprehensive Review on Biological and Pharmacological Insights
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-09-15
DOI
10.3389/fphar.2020.498758
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Ethnopharmacological Applications Targeting Alcohol Abuse: Overview and Outlook
- (2020) Laxman Singh et al. Frontiers in Pharmacology
- Phytopharmacology and Clinical Updates of Berberis Species Against Diabetes and Other Metabolic Diseases
- (2020) Tarun Belwal et al. Frontiers in Pharmacology
- Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence
- (2019) Marziyeh Hajialyani et al. MOLECULES
- Lycopus lucidus Turcz Inhibits the Osteoclastogenesis in RAW 264.7 Cells and Bone Loss in Ovariectomized Rat Model
- (2019) Da-Won Jeong et al. Evidence-based Complementary and Alternative Medicine
- Phytochemicals as potent modulators of autophagy for cancer therapy
- (2018) Mohammad Amin Moosavi et al. CANCER LETTERS
- Mechanistic insight into contextual TGF-β signaling
- (2018) Ying E Zhang CURRENT OPINION IN CELL BIOLOGY
- IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045
- (2018) N.H. Cho et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- The role of TGF-β/SMAD4 signaling in cancer
- (2018) Ming Zhao et al. International Journal of Biological Sciences
- Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways
- (2018) Jiao Feng et al. Drug Design Development and Therapy
- Silymarin ameliorates diabetic cardiomyopathy via inhibiting TGF-β1/Smad signaling
- (2018) Songyan Meng et al. CELL BIOLOGY INTERNATIONAL
- mTORC1 Overactivation as a Key Aging Factor in the Progression to Type 2 Diabetes Mellitus
- (2018) Carlos Guillén et al. Frontiers in Endocrinology
- Vitamin D improves the content of TGF-β and IGF-1 in intervertebral disc of diabetic rats
- (2017) Ji-long An et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes
- (2017) Huige Li et al. EXPERIMENTAL CELL RESEARCH
- TGF-β1/Smad3 Pathway Targets PP2A-AMPK-FoxO1 Signaling to Regulate Hepatic Gluconeogenesis
- (2017) Hariom Yadav et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prevention of renal apoB retention is protective against diabetic nephropathy: role of TGF-β inhibition
- (2017) Patricia G. Wilson et al. JOURNAL OF LIPID RESEARCH
- Adiponectin improves insulin sensitivity via activation of autophagic flux
- (2017) Penny Ahlstrom et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Puerarin Protects against Cardiac Fibrosis Associated with the Inhibition of TGF-β1/Smad2-Mediated Endothelial-to-Mesenchymal Transition
- (2017) Ya-Ge Jin et al. PPAR Research
- Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes
- (2017) Andreas Buch Møller et al. Scientific Reports
- Alterations in Mitochondrial Oxidative Stress and Mitophagy in Subjects with Prediabetes and Type 2 Diabetes Mellitus
- (2017) Shipra Bhansali et al. Frontiers in Endocrinology
- Limited Alzheimer-Type Neurodegeneration in Experimental Obesity and Type 2 Diabetes Mellitus
- (2017) Natalie Moroz et al. JOURNAL OF ALZHEIMERS DISEASE
- Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways
- (2017) Liwei Wu et al. Scientific Reports
- TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy
- (2016) Ana García-Aguilar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Subcutaneous administration of liraglutide ameliorates learning and memory impairment by modulating tau hyperphosphorylation via the glycogen synthase kinase-3β pathway in an amyloid β protein induced alzheimer disease mouse model
- (2016) Liqin Qi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Autophagy links β-catenin and Smad signaling to promote epithelial-mesenchymal transition via upregulation of integrin linked kinase
- (2016) Min Pang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion
- (2016) Yubin Wang et al. Molecular Medicine Reports
- Exendin-4 Reverses Biochemical and Functional Alterations in the Blood–Brain and Blood–CSF Barriers in Diabetic Rats
- (2016) Caroline Zanotto et al. MOLECULAR NEUROBIOLOGY
- Quercetin-Rich Guava (Psidium guajava) Juice in Combination with Trehalose Reduces Autophagy, Apoptosis and Pyroptosis Formation in the Kidney and Pancreas of Type II Diabetic Rats
- (2016) Chia-Fa Lin et al. MOLECULES
- TOR Complexes and the Maintenance of Cellular Homeostasis
- (2016) Sandra Eltschinger et al. TRENDS IN CELL BIOLOGY
- Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy
- (2016) Chuanyong Guo et al. Drug Design Development and Therapy
- Efficacy and safety of liraglutide for overweight adult patients with type 1 diabetes and insufficient glycaemic control (Lira-1): a randomised, double-blind, placebo-controlled trial
- (2016) Thomas Fremming Dejgaard et al. Lancet Diabetes & Endocrinology
- Beclin-1- mediated autophagy may be involved in the elderly cognitive and affective disorders in streptozotocin-induced diabetic mice
- (2016) Zhu-Fei Guan et al. Translational Neurodegeneration
- The DPP4 Inhibitor Linagliptin Protects from Experimental Diabetic Retinopathy
- (2016) Nadine Dietrich et al. PLoS One
- The Neuroprotection of Liraglutide Against Ischaemia-induced Apoptosis through the Activation of the PI3K/AKT and MAPK Pathways
- (2016) Huili Zhu et al. Scientific Reports
- Metformin is a novel suppressor for transforming growth factor (TGF)-β1
- (2016) Han Xiao et al. Scientific Reports
- Is Autophagy Altered in the Leukocytes of Type 2 Diabetic Patients?
- (2015) Susana Rovira-Llopis et al. ANTIOXIDANTS & REDOX SIGNALING
- Emerging role of autophagy in mediating widespread actions of ADIPOQ/adiponectin
- (2015) Aimin Xu et al. Autophagy
- Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-κB and TGF-β1/Smad-2/-3 pathways
- (2015) Haiying Tang et al. CELL STRESS & CHAPERONES
- Topical Application of Propolis Enhances Cutaneous Wound Healing by Promoting TGF-Beta/Smad-Mediated Collagen Production in a Streptozotocin-Induced Type I Diabetic Mouse Model
- (2015) Wael N. Hozzein et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Topical administration of GLP-1 receptor agonists prevents retinal neurodegeneration in experimental diabetes
- (2015) Cristina Hernández et al. DIABETES
- Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study
- (2015) Christian S. Frandsen et al. DIABETES CARE
- Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetes
- (2015) Rikke Kruse et al. DIABETOLOGIA
- Upregulation ofmicroRNA-126in Hepatic Stellate Cells May Affect Pathogenesis of Liver Fibrosis Through theNF-κBPathway
- (2015) Xiao Feng et al. DNA AND CELL BIOLOGY
- Pressure Overload-Induced Cardiac Dysfunction in Aged Male Adiponectin Knockout Mice Is Associated With Autophagy Deficiency
- (2015) James Won Suk Jahng et al. ENDOCRINOLOGY
- Variation in nutritional compositions, antioxidant activity and microstructure of Lycopus lucidus Turcz. root at different harvest times
- (2015) Yue-hong Lu et al. FOOD CHEMISTRY
- Liraglutide is neurotrophic and neuroprotective in neuronal cultures and mitigates mild traumatic brain injury in mice
- (2015) Yazhou Li et al. JOURNAL OF NEUROCHEMISTRY
- Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway
- (2015) Linying Shi et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Protective Effects of Red Guava on Inflammation and Oxidative Stress in Streptozotocin-Induced Diabetic Mice
- (2015) Pei-Ying Li et al. MOLECULES
- Ezetimibe improves hepatic steatosis in relation to autophagy in obese and diabetic rats
- (2015) Eugene Chang WORLD JOURNAL OF GASTROENTEROLOGY
- Puerarin attenuates the inflammatory response and apoptosis in LPS-stimulated cardiomyocytes
- (2015) YUAN YUAN et al. Experimental and Therapeutic Medicine
- Combination of Active Components of Xiexin Decoction Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad Pathways in db/db Diabetic Mice
- (2015) Jia-Sheng Wu et al. PLoS One
- Is Glycemic Control Modulating Endoplasmic Reticulum Stress in Leukocytes of Type 2 Diabetic Patients?
- (2014) Susana Rovira-Llopis et al. ANTIOXIDANTS & REDOX SIGNALING
- Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
- (2014) Suchithra Menon et al. CELL
- Pancreatic -Cell Failure Mediated by mTORC1 Hyperactivity and Autophagic Impairment
- (2014) A. Bartolome et al. DIABETES
- Phytochemical, Phytotherapeutical and Pharmacological Study ofMomordica dioica
- (2014) Sattya Narayan Talukdar et al. Evidence-based Complementary and Alternative Medicine
- Hepatoprotective Effects ofSilybum marianum(Silymarin) andGlycyrrhiza glabra(Glycyrrhizin) in Combination: A Possible Synergy
- (2014) Mahmood Rasool et al. Evidence-based Complementary and Alternative Medicine
- Molecular Mechanism and Treatment of Viral Hepatitis-Related Liver Fibrosis
- (2014) Tung-Hung Su et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Human IAPP–induced pancreatic β cell toxicity and its regulation by autophagy
- (2014) Nayumi Shigihara et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity
- (2014) Jacqueline F. Rivera et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy in diabetic nephropathy
- (2014) Yan Ding et al. JOURNAL OF ENDOCRINOLOGY
- The putative role of proteolytic pathways in the pathogenesis of Type 1 diabetes mellitus: The ‘autophagy’ hypothesis
- (2014) Alessandra Fierabracci MEDICAL HYPOTHESES
- Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats
- (2014) Marie-Soleil Beaudoin et al. Obesity
- Low vitamin D concentrations may contribute to the increased risk of diabetes mellitus related to shift work
- (2014) William B Grant OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
- Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models
- (2014) Hamideh Parhiz et al. PHYTOTHERAPY RESEARCH
- Role of islet β cell autophagy in the pathogenesis of diabetes
- (2014) Myung-Shik Lee TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes
- (2014) Yu-Mi Lim et al. Nature Communications
- Effects of puerarin in STZ-induced diabetic rats by oxidative stress and the TGF-β1/Smad2 pathway
- (2014) ShaoYi She et al. Food & Function
- Momordica charantia ointment accelerates diabetic wound healing and enhances transforming growth factor-β expression
- (2014) F. Hussan et al. Journal of Wound Care
- Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin
- (2013) Kenneth K.Y. Cheng et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Effect of Liraglutide on endoplasmic reticulum stress in diabetes
- (2013) Linlin Zhao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Crosstalk between apoptosis, necrosis and autophagy
- (2013) Vassiliki Nikoletopoulou et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Measurement of urinary TGF-β1 in patients with diabetes mellitus and normal controls
- (2013) Mykola V. Tsapenko et al. CLINICAL BIOCHEMISTRY
- Human Leukocyte/Endothelial Cell Interactions and Mitochondrial Dysfunction in Type 2 Diabetic Patients and Their Association With Silent Myocardial Ischemia
- (2013) A. Hernandez-Mijares et al. DIABETES CARE
- Exendin-4 Improves β-Cell Function in Autophagy-Deficient β-Cells
- (2013) Hiroko Abe et al. ENDOCRINOLOGY
- Inhibition of dipeptidyl peptidase activity by flavonol glycosides of guava (Psidium guajava L.): A key to the beneficial effects of guava in type II diabetes mellitus
- (2013) Thomas Eidenberger et al. FITOTERAPIA
- Phenolic-rich extract from the Costa Rican guava (Psidium friedrichsthalianum) pulp with antioxidant and anti-inflammatory activity. Potential for COPD therapy
- (2013) Gema Flores et al. FOOD CHEMISTRY
- Neuroprotective Effects of Liraglutide for Stroke Model of Rats
- (2013) Kenichiro Sato et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Green Tea Extract Decreases Oxidative Stress and Improves Insulin Sensitivity in an Animal Model of Insulin Resistance, the Fructose-Fed Rat
- (2013) Isabelle Hininger-Favier et al. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
- Relationship between Serum Transforming Growth Factorβ1 Concentrations and the Duration of Type 1 Diabetes Mellitus in Children and Adolescents
- (2013) Katarzyna Zorena et al. MEDIATORS OF INFLAMMATION
- A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity
- (2013) Miki Okada-Iwabu et al. NATURE
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- The aqueous extract of Lycopus lucidus Turcz ameliorates streptozotocin-induced diabetic renal damage via inhibiting TGF-β1 signaling pathway
- (2013) Yuanzhang Yao et al. PHYTOMEDICINE
- Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies
- (2013) Zhichun Chen et al. PROGRESS IN NEUROBIOLOGY
- Vitamin D Intake and Risk of Type 1 Diabetes: A Meta-Analysis of Observational Studies
- (2013) Jia-Yi Dong et al. Nutrients
- Impaired autophagic function in rat islets with aging
- (2012) Yu Liu et al. AGE
- Mitophagy: mechanisms, pathophysiological roles, and analysis
- (2012) Wen-Xing Ding et al. BIOLOGICAL CHEMISTRY
- Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1α, MIP-2, KC, CX3CL1 and TGF-β in wounded tissue
- (2012) Gamal Badr et al. BMC IMMUNOLOGY
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- The Immunomodulatory and Anticancer Properties of Propolis
- (2012) Godfrey Chi-Fung Chan et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Dorothy Hodgkin Lecture 2012* Non-alcoholic fatty liver disease, insulin resistance and ectopic fat: a new problem in diabetes management
- (2012) C. D. Byrne DIABETIC MEDICINE
- Circulating TGF-β1, Glycation, and Oxidation in Children with Diabetes Mellitus Type 1
- (2012) Vladimír Jakuš et al. Experimental Diabetes Research
- The anticancer activity of propolis
- (2012) Diana Sawicka et al. FOLIA HISTOCHEMICA ET CYTOBIOLOGICA
- Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues
- (2012) Virginia Hernández–Gea et al. GASTROENTEROLOGY
- TGF- -induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion
- (2012) S. Lamouille et al. JOURNAL OF CELL SCIENCE
- Association of β-catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF-β1
- (2012) Xinrui Tian et al. JOURNAL OF CELL SCIENCE
- Ethnobotanical survey of medicinal plants used by Bapedi healers to treat diabetes mellitus in the Limpopo Province, South Africa
- (2012) S. Semenya et al. JOURNAL OF ETHNOPHARMACOLOGY
- Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
- (2012) Kook Hwan Kim et al. NATURE MEDICINE
- Liraglutide protects against amyloid-β protein-induced impairment of spatial learning and memory in rats
- (2012) Wei-Na Han et al. NEUROBIOLOGY OF AGING
- Renal Protective Effects of Extracts from Guava Fruit (Psidium guajava L.) in Diabetic Mice
- (2012) Chia-Yun Lin et al. PLANT FOODS FOR HUMAN NUTRITION
- GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy
- (2012) S.-Y. Lin et al. SCIENCE
- Chaperone-mediated autophagy: a unique way to enter the lysosome world
- (2012) Susmita Kaushik et al. TRENDS IN CELL BIOLOGY
- The crosstalk between autophagy and apoptosis: where does this lead?
- (2012) Claire Gordy et al. Protein & Cell
- Glucagon-like peptide 1 receptor plays a critical role in geniposide-regulated insulin secretion in INS-1 cells
- (2011) Li-xia Guo et al. ACTA PHARMACOLOGICA SINICA
- Chronic administration of ezetimibe increases active glucagon-like peptide-1 and improves glycemic control and pancreatic beta cell mass in a rat model of type 2 diabetes
- (2011) Soo Jin Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats
- (2011) Kuan-Hsing Chen et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Maternal Serum Levels of 25-Hydroxy-Vitamin D During Pregnancy and Risk of Type 1 Diabetes in the Offspring
- (2011) I. M. Sorensen et al. DIABETES
- Determination and Comparison of γ-Aminobutyric Acid (GABA) Content in Pu-erh and Other Types of Chinese Tea
- (2011) Ming Zhao et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Axin Pathway Activity Regulatesin VivopY654-β-catenin Accumulation and Pulmonary Fibrosis
- (2011) Arnau Ulsamer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Vitamin D and diabetes: Its importance for beta cell and immune function
- (2011) Heidi Wolden-Kirk et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Impaired TGF-β signaling and a defect in resolution of inflammation contribute to delayed wound healing in a female rat model of type 2 diabetes
- (2011) Fahd Al-Mulla et al. Molecular BioSystems
- NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma
- (2011) Tom Luedde et al. Nature Reviews Gastroenterology & Hepatology
- Tubular Overexpression of Transforming Growth Factor-β1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells
- (2010) Robert Koesters et al. AMERICAN JOURNAL OF PATHOLOGY
- The emerging role of autophagy in the pathophysiology of diabetes mellitus
- (2010) Claudio D. Gonzalez et al. Autophagy
- Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions
- (2010) J F Rivera et al. CELL DEATH AND DIFFERENTIATION
- Protein misfolding disorders and macroautophagy
- (2010) Fiona M Menzies et al. CURRENT OPINION IN CELL BIOLOGY
- Role of the TSC1-TSC2 Complex in the Integration of Insulin and Glucose Signaling Involved in Pancreatic β-Cell Proliferation
- (2010) Alberto Bartolomé et al. ENDOCRINOLOGY
- Polyphenol contents and antioxidant activity of lyophilized aqueous extract of propolis from Erzurum, Turkey
- (2010) İlhami Gülçin et al. FOOD AND CHEMICAL TOXICOLOGY
- Anticancer, antioxidant and antimicrobial activities of the essential oil of Lycopus lucidus Turcz. var. hirtus Regel
- (2010) Jian-Qing Yu et al. FOOD CHEMISTRY
- TGF-β2 Suppresses Macrophage Cytokine Production and Mucosal Inflammatory Responses in the Developing Intestine
- (2010) Akhil Maheshwari et al. GASTROENTEROLOGY
- TGF-β1 Protects against Mesangial Cell Apoptosis via Induction of Autophagy
- (2010) Yan Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Macroautophagy Regulates Energy Metabolism during Effector T Cell Activation
- (2010) V. M. Hubbard et al. JOURNAL OF IMMUNOLOGY
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a
- (2010) Huanxin Lin et al. PLoS One
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- Regulation of autophagy by ROS: physiology and pathology
- (2010) Ruth Scherz-Shouval et al. TRENDS IN BIOCHEMICAL SCIENCES
- Autophagy protects against human islet amyloid polypeptide-associated apoptosis
- (2010) Shuhei Morita et al. Journal of Diabetes Investigation
- Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-β1 in Renal Tubular Epithelial Cells
- (2009) Guoping Zheng et al. AMERICAN JOURNAL OF PATHOLOGY
- The role of autophagy in pancreatic β-cell and diabetes
- (2009) Yoshio Fujitani et al. Autophagy
- Autophagy and the pancreatic beta-cell in human type 2 diabetes
- (2009) Piero Marchetti et al. Autophagy
- The MAP1-LC3 conjugation system is involved in lipid droplet formation
- (2009) Masahiro Shibata et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Emerging common themes in regulation of PIKKs and PI3Ks
- (2009) Harri Lempiäinen et al. EMBO JOURNAL
- Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts
- (2009) Young Kim et al. JOURNAL OF CELL BIOLOGY
- Autophagy regulates adipose mass and differentiation in mice
- (2009) Rajat Singh et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy-Mediated Insulin Receptor Down-Regulation Contributes to Endoplasmic Reticulum Stress-Induced Insulin Resistance
- (2009) L. Zhou et al. MOLECULAR PHARMACOLOGY
- Incretin-based therapies for type 2 diabetes mellitus
- (2009) Julie A. Lovshin et al. Nature Reviews Endocrinology
- Molecular mechanisms of mTOR-mediated translational control
- (2009) Xiaoju Max Ma et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
- (2009) Y. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Shared Principles in NF-κB Signaling
- (2008) Matthew S. Hayden et al. CELL
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
- (2008) Hye Seung Jung et al. Cell Metabolism
- Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet
- (2008) Chie Ebato et al. Cell Metabolism
- TGF-β coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival
- (2008) Anne Gingery et al. EXPERIMENTAL CELL RESEARCH
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- Autophagy and VMP1 Expression Are Early Cellular Events in Experimental Diabetes
- (2008) Daniel Grasso et al. PANCREATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation