Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes
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Title
Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes
Authors
Keywords
-
Journal
Nature Communications
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-09-26
DOI
10.1038/ncomms5934
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Note: Only part of the references are listed.- Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes
- (2014) Jinyoung Kim et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2013) Na-Ri Shin et al. GUT
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- (2013) Di Ma et al. MOLECULAR ENDOCRINOLOGY
- Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
- (2013) Takuma Misawa et al. NATURE IMMUNOLOGY
- Overexpression of Atg5 in mice activates autophagy and extends lifespan
- (2013) Jong-Ok Pyo et al. Nature Communications
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- Loss of Autophagy in Pro-opiomelanocortin Neurons Perturbs Axon Growth and Causes Metabolic Dysregulation
- (2012) Bérengère Coupé et al. Cell Metabolism
- Loss of autophagy in hypothalamic POMC neurons impairs lipolysis
- (2012) Susmita Kaushik et al. EMBO REPORTS
- Role of Hypothalamic Proopiomelanocortin Neuron Autophagy in the Control of Appetite and Leptin Response
- (2012) Wenying Quan et al. ENDOCRINOLOGY
- Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
- (2012) Congcong He et al. NATURE
- Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
- (2012) Kook Hwan Kim et al. NATURE MEDICINE
- Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice
- (2011) W. Quan et al. DIABETOLOGIA
- C-Kit controls IL-1β-induced effector functions in HMC-cells
- (2011) Sebastian Drube et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance
- (2011) Myoung Sook Han et al. JOURNAL OF LIPID RESEARCH
- Novel Regulation of Parkin Function through c-Abl-Mediated Tyrosine Phosphorylation: Implications for Parkinson's Disease
- (2011) S. Z. Imam et al. JOURNAL OF NEUROSCIENCE
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation
- (2010) Masahiro Shibata et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance
- (2010) Ling Yang et al. Cell Metabolism
- Altered lipid content inhibits autophagic vesicular fusion
- (2010) Hiroshi Koga et al. FASEB JOURNAL
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation
- (2010) Jose A. Rodríguez-Navarro et al. NEUROBIOLOGY OF DISEASE
- Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST)
- (2010) A. Gupta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy Suppresses Tumorigenesis through Elimination of p62
- (2009) Robin Mathew et al. CELL
- Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells
- (2009) Sung Hoon Back et al. Cell Metabolism
- Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice
- (2009) M. S. Han et al. DIABETES
- Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells
- (2009) Cristian Bellodi et al. JOURNAL OF CLINICAL INVESTIGATION
- Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice
- (2009) Anurag Kumar Singh et al. JOURNAL OF CLINICAL INVESTIGATION
- Mantle skewness and ridge segmentation
- (2009) Satish C. Singh et al. NATURE
- A crucial role for adipose tissue p53 in the regulation of insulin resistance
- (2009) Tohru Minamino et al. NATURE MEDICINE
- Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence
- (2009) P. Rai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
- (2009) Y. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comprehensive proteomics analysis of autophagy-deficient mouse liver
- (2008) Naomi Matsumoto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2008) Hye Seung Jung et al. Cell Metabolism
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- (2008) M. Fraenkel et al. DIABETES
- Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells
- (2008) Takashi Shingu et al. INTERNATIONAL JOURNAL OF CANCER
- Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
- (2008) Tatsuya Saitoh et al. NATURE
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