Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE

Hypoxia and the hypoxia inducible factor 1α activate protein kinase A by repressing RII beta subunit transcription

(2020) Kristin Lucia et al.   ONCOGENE

Csf1 Deficiency Dysregulates Glial Responses to Demyelination and Disturbs CNS White Matter Remyelination

(2020) Bartosz Wylot et al.   Cells

Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway

(2020) Yu Li et al.   Frontiers in Cell and Developmental Biology

Hydrogen attenuates radiation-induced intestinal damage by reducing oxidative stress and inflammatory response

(2020) Xiaochen Qiu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCε pathway in a rat model of neonatal HIE

(2020) Xiao Hu et al.   Journal of Neuroinflammation

CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE

(2019) Agnieszka Wlodarczyk et al.   Frontiers in Cellular Neuroscience

Royal Jelly Alleviates Cognitive Deficits and β-Amyloid Accumulation in APP/PS1 Mouse Model Via Activation of the cAMP/PKA/CREB/BDNF Pathway and Inhibition of Neuronal Apoptosis

(2019) Mengmeng You et al.   Frontiers in Aging Neuroscience

The Role of Oxidative Stress in Microvascular Disturbances after Experimental Subarachnoid Hemorrhage

(2019) Toshio Fumoto et al.   Translational Stroke Research

Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer’s disease

(2019) Darshpreet Kaur et al.   INFLAMMOPHARMACOLOGY

Neuroprotection Induced by Energy and Protein-Energy Undernutrition Is Phase-Dependent After Focal Cerebral Ischemia in Mice

(2019) Tayana Silva de Carvalho et al.   Translational Stroke Research

Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

(2019) Lorenza Magno et al.   Alzheimers Research & Therapy

Liraglutide and its Neuroprotective Properties—Focus on Possible Biochemical Mechanisms in Alzheimer’s Disease and Cerebral Ischemic Events

(2019) Michał Wiciński et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes

(2019) Jinda Huang et al.   Oxidative Medicine and Cellular Longevity

Exploration of MST1-Mediated Secondary Brain Injury Induced by Intracerebral Hemorrhage in Rats via Hippo Signaling Pathway

(2019) Peng Zhang et al.   Translational Stroke Research

Mechanism and Treatment Related to Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy

(2019) Xingping Qin et al.   Frontiers in Molecular Neuroscience

CSF-1 controls cerebellar microglia and is required for motor function and social interaction

(2019) Veronika Kana et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina

(2019) Levi Todd et al.   Journal of Neuroinflammation

PKA- and Ca2+-dependent p38 MAPK/CREB activation protects against manganese-mediated neuronal apoptosis

(2019) Ganlin Zhu et al.   TOXICOLOGY LETTERS

Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood–Brain Barrier Integrity in Stroke

(2019) Yuan Zhang et al.   Translational Stroke Research

Ghrelin attenuates oxidative stress and neuronal apoptosis via GHSR-1α/AMPK/Sirt1/PGC-1α/UCP2 pathway in a rat model of neonatal HIE

(2019) Juan Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions

(2019) Courtney Easley-Neal et al.   Frontiers in Immunology

Association between CSF1 and CSF1R Polymorphisms and Parkinson’s Disease in Taiwan

(2019) Kuo-Hsuan Chang et al.   Journal of Clinical Medicine

Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization

(2019) Won-Kyu Ju et al.   Oxidative Medicine and Cellular Longevity

Ginsenoside Rb1 Promotes Motor Functional Recovery and Axonal Regeneration in Post-stroke Mice through cAMP/PKA/CREB Signaling Pathway

(2019) Xuan Gao et al.   BRAIN RESEARCH BULLETIN

Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune system

(2019) Zhiguang Wu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Oxidative Stress Induces Neuronal Apoptosis Through Suppressing Transcription Factor EB Phosphorylation at Ser467

(2018) Qian Su et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A Long Journey into Aging, Brain Aging, and Alzheimer’s Disease Following the Oxidative Stress Tracks

(2018) Patrizia Mecocci et al.   JOURNAL OF ALZHEIMERS DISEASE

Astrocyte truncated-TrkB mediates BDNF antiapoptotic effect leading to neuroprotection

(2018) Julieta Saba et al.   JOURNAL OF NEUROCHEMISTRY

Increased Microglial CSF1R Expression in the SIV/Macaque Model of HIV CNS Disease

(2018) Audrey C Knight et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The AMPK-PGC-1α signaling axis regulates the astrocyte glutathione system to protect against oxidative and metabolic injury

(2018) Xiaoxin Guo et al.   NEUROBIOLOGY OF DISEASE

Dyslipidemia-associated atherogenic oxidized lipids induce platelet hyperactivity through phospholipase Cγ2-dependent reactive oxygen species generation

(2018) Martin Berger et al.   PLATELETS

Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes

(2018) Myoung Sup Shim et al.   Cell Death & Disease

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential

(2018) Sonia Boulakirba et al.   Scientific Reports

PAI-1 but Not PAI-2 Gene Deficiency Attenuates Ischemic Brain Injury After Experimental Stroke

(2018) Eva-Verena Griemert et al.   Translational Stroke Research

Protective Role of UCP2 in Oxidative Stress and Apoptosis during the Silent Phase of an Experimental Model of Epilepsy Induced by Pilocarpine

(2018) Marina Rascio Henriques Dutra et al.   Oxidative Medicine and Cellular Longevity

MMP10 Promotes Efficient Thrombolysis After Ischemic Stroke in Mice with Induced Diabetes

(2018) Manuel Navarro-Oviedo et al.   Translational Stroke Research

AVE 0991 attenuates oxidative stress and neuronal apoptosis via Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats

(2018) Jun Mo et al.   Redox Biology

Hearing impairment and hypoxia ischaemic encephalopathy: Incidence and associated factors

(2018) Michael P. Fitzgerald et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice

(2017) Javier A. Carrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial function in hypoxic ischemic injury and influence of aging

(2017) P. Benson Ham et al.   PROGRESS IN NEUROBIOLOGY

From the Cover: AstrocytesAre Protective Against Chlorpyrifos Developmental Neurotoxicity in Human Pluripotent Stem Cell-Derived Astrocyte-Neuron Cocultures

(2017) Xian Wu et al.   TOXICOLOGICAL SCIENCES

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development

(2017) Mei Yu et al.   Nature Communications

Upregulation of UCP2 in beta-cells confers partial protection against both oxidative stress and glucotoxicity

(2017) Ning Li et al.   Redox Biology

The association between antioxidant enzyme polymorphisms and cerebral palsy after perinatal hypoxic-ischaemic encephalopathy

(2016) Katarina Esih et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Resveratrol Reverses the Synaptic Plasticity Deficits in a Chronic Cerebral Hypoperfusion Rat Model

(2016) Huagang Li et al.   Journal of Stroke & Cerebrovascular Diseases

Mitochondrial Dysfunction Contributes to Hypertensive Target Organ Damage: Lessons from an Animal Model of Human Disease

(2016) Speranza Rubattu et al.   Oxidative Medicine and Cellular Longevity

Resveratrol Reverses the Synaptic Plasticity Deficits in a Chronic Cerebral Hypoperfusion Rat Model

(2016) Huagang Li et al.   Journal of Stroke & Cerebrovascular Diseases

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

(2015) Sandrine Obba et al.   Autophagy

Brain Barrier Properties and Cerebral Blood Flow in Neonatal Mice Exposed to Cerebral Hypoxia-Ischemia

(2015) C Joakim Ek et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Injured sensory neuron–derived CSF1 induces microglial proliferation and DAP12-dependent pain

(2015) Zhonghui Guan et al.   NATURE NEUROSCIENCE

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

(2013) Jian Luo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phospholipase C-γ2 via p38 and ERK1/2 MAP kinase mediates diperoxovanadate-asparagine induced human platelet aggregation and sCD40L release

(2013) Ankita Misra et al.   REDOX REPORT

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation

(2012) Sayan Nandi et al.   DEVELOPMENTAL BIOLOGY

Dysfunctional Mitochondria Modulate cAMP-PKA Signaling and Filamentous and Invasive Growth of Saccharomyces cerevisiae

(2012) A. Aun et al.   GENETICS

Microglial activation in stroke: Therapeutic targets

(2010) Midori A. Yenari et al.   Neurotherapeutics

Neuroprotective Role of Mitochondrial Uncoupling Protein 2 in Cerebral Stroke

(2009) Suresh L Mehta et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM