The potential health effects of dietary phytoestrogens

Soy isoflavones and glucose metabolism in menopausal women: A systematic review and meta-analysis of randomized controlled trials

(2016) Ke Fang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein

(2015) Jana Koo et al.   BMC CANCER

Soya products and serum lipids: a meta-analysis of randomised controlled trials

(2015) Oluwabunmi A. Tokede et al.   BRITISH JOURNAL OF NUTRITION

Diet and cognitive decline at middle age: the role of antioxidants

(2015) Astrid C. J. Nooyens et al.   BRITISH JOURNAL OF NUTRITION

The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The effect of glucuronidation on isoflavone induced estrogen receptor (ER)α and ERβ mediated coregulator interactions

(2015) Karsten Beekmann et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Soy Intake Is Associated With Lower Endometrial Cancer Risk

(2015) Guo-Qiang Zhang et al.   MEDICINE

Dietary isoflavones and bone mineral density during midlife and the menopausal transition

(2015) Gail A. Greendale et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

(2015) Christopher Southan et al.   NUCLEIC ACIDS RESEARCH

Schisandrin C Ameliorates Learning and Memory Deficits by Aβ1-42-induced Oxidative Stress and Neurotoxicity in Mice

(2015) Xin Mao et al.   PHYTOTHERAPY RESEARCH

Deconjugation of soy isoflavone glucuronides needed for estrogenic activity

(2015) M.A. Islam et al.   TOXICOLOGY IN VITRO

Phytoestrogens and risk of prostate cancer: a meta-analysis of observational studies

(2015) Jinjing He et al.   World Journal of Surgical Oncology

Phytoestrogen Intake and Risk of Ovarian Cancer: a Meta-Analysis of 10 Observational Studies

(2015) Xin-Lan Qu et al.   Asian Pacific Journal of Cancer Prevention

Psoralidin, a coumestan analogue, as a novel potent estrogen receptor signaling molecule isolated from Psoralea corylifolia

(2014) Xiyuan Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Therapeutic perspectives of epigenetically active nutrients

(2014) M Remely et al.   BRITISH JOURNAL OF PHARMACOLOGY

Enterolignan-Producing Phenotypes Are Associated with Increased Gut Microbial Diversity and Altered Composition in Premenopausal Women in the United States

(2014) M. A. J. Hullar et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Identification of coregulators influenced by estrogen receptor subtype specific binding of the ER antagonists 4-hydroxytamoxifen and fulvestrant

(2014) Nynke M. Evers et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Efficacy of phytoestrogens for menopausal symptoms: a meta-analysis and systematic review

(2014) M-n. Chen et al.   CLIMACTERIC

Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ERα and ERβ agonists

(2014) Nynke M. Evers et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Phytoestrogens and cognitive function: a review

(2014) Mira Soni et al.   MATURITAS

Ovarian Conservation at the Time of Hysterectomy and Long-Term Health Outcomes in the Nurses’ Health Study

(2014) William H. Parker et al.   OBSTETRICS AND GYNECOLOGY

Schisantherin A recovers Aβ-induced neurodegeneration with cognitive decline in mice

(2014) Xiaolong Li et al.   PHYSIOLOGY & BEHAVIOR

Erythroidine Alkaloids: A Novel Class of Phytoestrogens

(2014) Sefirin Djiogue et al.   PLANTA MEDICA

Association between Soy Isoflavone Intake and Breast Cancer Risk for Pre- and Post-Menopausal Women: A Meta-Analysis of Epidemiological Studies

(2014) Meinan Chen et al.   PLoS One

Evidence of ERalpha and ERbeta selectivity and partial estrogen agonism in traditional Chinese medicine

(2014) Dov Tiosano et al.   Reproductive Biology and Endocrinology

Impact of Soy Isoflavones on the Epigenome in Cancer Prevention

(2014) Maria Pudenz et al.   Nutrients

Proliferative and estrogenic sensitivity of the mammary gland are modulated by isoflavones during distinct periods of adolescence

(2013) Almut F. Molzberger et al.   ARCHIVES OF TOXICOLOGY

Soy and soy isoflavones in prostate cancer: a systematic review and meta-analysis of randomized controlled trials

(2013) M. Diana van Die et al.   BJU INTERNATIONAL

Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments

(2013) Jia Yao et al.   BRAIN RESEARCH

Estrogen receptors and ischemic neuroprotection: Who, what, where, and when?

(2013) Derek A. Schreihofer et al.   BRAIN RESEARCH

DNA Methyltransferase-1 Inhibitors as Epigenetic Therapy for Cancer

(2013) Varinder Singh et al.   CURRENT CANCER DRUG TARGETS

The association between urinary phytoestrogen excretion and components of the metabolic syndrome in NHANES

(2013) Tristan Struja et al.   EUROPEAN JOURNAL OF NUTRITION

17β-Estradiol and genistein acute treatments improve some cerebral cortex homeostasis aspects deteriorated by aging in female rats

(2013) Javier Morán et al.   EXPERIMENTAL GERONTOLOGY

The effects of lignan-riched extract of Shisandra chinensis on amyloid-β-induced cognitive impairment and neurotoxicity in the cortex and hippocampus of mouse

(2013) Eun Ju Jeong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Phytoestrogens and the metabolic syndrome

(2013) Alois Jungbauer et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Effects of soy isoflavones on mammographic density and breast parenchyma in postmenopausal women

(2013) Armando Delmanto et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Soy, Red Clover, and Isoflavones and Breast Cancer: A Systematic Review

(2013) Heidi Fritz et al.   PLoS One

Activation of Estrogen Receptor by Bavachin from Psoralea corylifolia

(2012) Joon-Woo Park et al.   Biomolecules & Therapeutics

Soy Isoflavone Supplementation for Breast Cancer Risk Reduction: A Randomized Phase II Trial

(2012) S. A. Khan et al.   Cancer Prevention Research

Endometrial, breast and liver safety of soy isoflavones plus Lactobacillus sporogenes in post-menopausal women

(2012) Nicola Colacurci et al.   GYNECOLOGICAL ENDOCRINOLOGY

Phytoestrogen intake from foods, during adolescence and adulthood, and risk of breast cancer by estrogen and progesterone receptor tumor subgroup among Ontario women

(2012) Laura N. Anderson et al.   INTERNATIONAL JOURNAL OF CANCER

Use of isoflavone supplements is associated with reduced postmenopausal breast cancer risk

(2012) Beatrice A. Boucher et al.   INTERNATIONAL JOURNAL OF CANCER

Phytoestrogens for menopausal symptoms: A review

(2012) John A. Eden   MATURITAS

Dietary phytoestrogen intakes and cognitive function during the menopausal transition

(2012) Gail A. Greendale et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Extracted or synthesized soybean isoflavones reduce menopausal hot flash frequency and severity

(2012) Kyoko Taku et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Mechanisms underlying the dualistic mode of action of major soy isoflavones in relation to cell proliferation and cancer risks

(2012) Ivonne M. C. M. Rietjens et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Soy isoflavone supplementation could reduce body weight and improve glucose metabolism in non-Asian postmenopausal women—A meta-analysis

(2012) Yun-Bo Zhang et al.   NUTRITION

Schizandrin, an Antioxidant Lignan fromSchisandra chinensis,Ameliorates Aβ1–42-Induced Memory Impairment in Mice

(2012) Di Hu et al.   Oxidative Medicine and Cellular Longevity

Soy intake is associated with lower lung cancer risk: results from a meta-analysis of epidemiologic studies

(2011) Wan-Shui Yang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Genistein inhibits aggregation of exogenous amyloid-beta1–40 and alleviates astrogliosis in the hippocampus of rats

(2011) Maryam Bagheri et al.   BRAIN RESEARCH

Estimated enterolignans, lignan-rich foods and fibre in relation to survival after postmenopausal breast cancer

(2011) K Buck et al.   BRITISH JOURNAL OF CANCER

Reduction of body weight, liver steatosis and expression of stearoyl-CoA desaturase 1 by the isoflavone daidzein in diet-induced obesity

(2011) A Crespillo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Plasma Isoflavones and the Risk of Lung Cancer in Women: A Nested Case-Control Study in Japan

(2011) T. Shimazu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Risks and benefits of dietary isoflavones for cancer

(2011) Susanne Andres et al.   CRITICAL REVIEWS IN TOXICOLOGY

Soy Isoflavones, CYP1A1, CYP1B1, and COMT Polymorphisms, and Breast Cancer: A Case–Control Study in Southwestern China

(2011) Qiong Wang et al.   DNA AND CELL BIOLOGY

Prevention of scopolamine-induced memory deficits by schisandrin B, an antioxidant lignan fromSchisandra chinensisin mice

(2011) Vijayasree V. Giridharan et al.   FREE RADICAL RESEARCH

The Effect of Soy Phytoestrogen Supplementation on Thyroid Status and Cardiovascular Risk Markers in Patients with Subclinical Hypothyroidism: A Randomized, Double-Blind, Crossover Study

(2011) Thozhukat Sathyapalan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genistein, Resveratrol, and 5-Aminoimidazole-4-carboxamide-1- -D-ribofuranoside Induce Cytochrome P450 4F2 Expression through an AMP-Activated Protein Kinase-Dependent Pathway

(2011) M.-H. Hsu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Proliferation assays for estrogenicity testing with high predictive value for the in vivo uterotrophic effect

(2011) Si Wang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estrogen receptor β-selective phytoestrogenic formulation prevents physical and neurological changes in a preclinical model of human menopause

(2011) Liqin Zhao et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

The G-protein-coupled estrogen receptor GPER in health and disease

(2011) Eric R. Prossnitz et al.   Nature Reviews Endocrinology

Meta-analyses of lignans and enterolignans in relation to breast cancer risk

(2010) Katharina Buck et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The EDKB: an established knowledge base for endocrine disrupting chemicals

(2010) Don Ding et al.   BMC BIOINFORMATICS

Borobudur revisited: Soy consumption may be associated with better recall in younger, but not in older, rural Indonesian elderly

(2010) Eef Hogervorst et al.   BRAIN RESEARCH

Soy isoflavones consumption and risk of breast cancer incidence or recurrence: a meta-analysis of prospective studies

(2010) Jia-Yi Dong et al.   BREAST CANCER RESEARCH AND TREATMENT

Genistein reduced the neural apoptosis in the brain of ovariectomised rats by modulating mitochondrial oxidative stress

(2010) Yan-Hong Huang et al.   BRITISH JOURNAL OF NUTRITION

Isoflavones from Phytoestrogens and Gastric Cancer Risk: A Nested Case-Control Study within the Korean Multicenter Cancer Cohort

(2010) K. P. Ko et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Specialty Supplements and Breast Cancer Risk in the VITamins And Lifestyle (VITAL) Cohort

(2010) T. M. Brasky et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The pros and cons of phytoestrogens

(2010) Heather B. Patisaul et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Impact of estrogen receptor alpha and beta agonists on delayed alternation in middle-aged rats

(2010) Steven L. Neese et al.   HORMONES AND BEHAVIOR

Estrogenic and Antiestrogenic Activities of Phytoalexins from Red Kidney Bean (Phaseolus vulgaris L.)

(2010) Stephen M. Boué et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Soybean Supplementation Helps Reverse Age- and Scopolamine-Induced Memory Deficits in Mice

(2010) Nitin Bansal et al.   JOURNAL OF MEDICINAL FOOD

The Antioxidant Effects of Genistein Are Associated with AMP-Activated Protein Kinase Activation and PTEN Induction in Prostate Cancer Cells

(2010) Chang Eun Park et al.   JOURNAL OF MEDICINAL FOOD

Is Soy Consumption Good or Bad for the Breast?

(2010) Leena Hilakivi‐Clarke et al.   JOURNAL OF NUTRITION

Isoflavones and cardiovascular disease

(2010) Antonio Cano et al.   MATURITAS

Dietary supplementation of soy germ phytoestrogens or estradiol improves spatial memory performance and increases gene expression of BDNF, TrkB receptor and synaptic factors in ovariectomized rats

(2010) Meixia Pan et al.   Nutrition & Metabolism

Is equol production beneficial to health?

(2010) Pamela J. Magee   PROCEEDINGS OF THE NUTRITION SOCIETY

Quantification of xanthohumol, isoxanthohumol, 8-prenylnaringenin, and 6-prenylnaringenin in hop extracts and derived capsules using secondary standards

(2010) Liene Dhooghe et al.   TALANTA

Soy consumption and prostate cancer risk in men: a revisit of a meta-analysis

(2009) Lin Yan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women’s Health Study

(2009) Sang-Ah Lee et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Side Effects of Phytoestrogens: A Meta-analysis of Randomized Trials

(2009) Clemens B. Tempfer et al.   AMERICAN JOURNAL OF MEDICINE

Genistein Inhibits Cell Growth by Modulating Various Mitogen-Activated Protein Kinases and AKT in Cervical Cancer Cells

(2009) Su-Hyeon Kim et al.   Annals of the New York Academy of Sciences

Comparative Study on the Nuclear Hormone Receptor Activity of Various Phytochemicals and Their Metabolites by Reporter Gene Assays Using Chinese Hamster Ovary Cells

(2009) Shinji Takeuchi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Sesaminol Glucosides Protect β-Amyloid Peptide-Induced Cognitive Deficits in Mice

(2009) Min Young Um et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Lignans and breast cancer risk in pre- and post-menopausal women: meta-analyses of observational studies

(2009) L S Velentzis et al.   BRITISH JOURNAL OF CANCER

Soya isoflavone supplementation enhances spatial working memory in men

(2009) Alicia A. Thorp et al.   BRITISH JOURNAL OF NUTRITION

Childhood Soy Intake and Breast Cancer Risk in Asian American Women

(2009) L. A. Korde et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The Use of Herbal Preparations to Alleviate Climacteric Disorders and Risk of Postmenopausal Breast Cancer in a German Case-Control Study

(2009) N. Obi et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Urinary Phytoestrogen Excretion and Postmenopausal Breast Cancer Risk: The Multiethnic Cohort Study

(2009) M. T. Goodman et al.   Cancer Prevention Research

Validation of a new yeast-based reporter assay consisting of human estrogen receptors α/β and coactivator SRC-1: Application for detection of estrogenic activity in environmental samples

(2009) Wai-Ling Chu et al.   ENVIRONMENTAL TOXICOLOGY

Estrogen-induced angiogenic factors derived from stromal and cancer cells are differently regulated by enterolactone and genistein in human breast cancer in vivo

(2009) Niina M. Saarinen et al.   INTERNATIONAL JOURNAL OF CANCER

Various Doses of Soy Isoflavones Do Not Modify Mammographic Density in Postmenopausal Women

(2009) Gertraud Maskarinec et al.   JOURNAL OF NUTRITION

Risk Assessment of Soybean-Based Phytoestrogens

(2009) Seung Jun Kwack et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Soy, phytoestrogens and metabolism: A review

(2009) Christopher R. Cederroth et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Efficacy of isoflavones in relieving vasomotor menopausal symptoms - A systematic review

(2009) Anja Jacobs et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Kinase mutations in human disease: interpreting genotype–phenotype relationships

(2009) Piya Lahiry et al.   NATURE REVIEWS GENETICS

Soy Isoflavones Have an Antiestrogenic Effect and Alter Mammary Promoter Hypermethylation in Healthy Premenopausal Women

(2009) Wenyi Qin et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Soy Food Consumption and Risk of Prostate Cancer: A Meta-Analysis of Observational Studies

(2009) Ye Won Hwang et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

The effect of genistein aglycone on cancer and cancer risk: a review of in vitro, preclinical, and clinical studies

(2009) Christopher K Taylor et al.   NUTRITION REVIEWS

A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women

(2008) C. E. Gleason et al.   AGE AND AGEING

The role of early life genistein exposures in modifying breast cancer risk

(2008) A Warri et al.   BRITISH JOURNAL OF CANCER

Epidemiology of soy exposures and breast cancer risk

(2008) A H Wu et al.   BRITISH JOURNAL OF CANCER

Soy Protein Containing Isoflavones and Mammographic Density in a Randomized Controlled Trial in Postmenopausal Women

(2008) M. Verheus et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

High Tofu Intake Is Associated with Worse Memory in Elderly Indonesian Men and Women

(2008) E. Hogervorst et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Degradation and metabolite formation of 17β-estradiol-3-sulphate in New Zealand pasture soils

(2008) Frank F. Scherr et al.   ENVIRONMENT INTERNATIONAL

Breast Safety and Efficacy of Genistein Aglycone for Postmenopausal Bone Loss: A Follow-Up Study

(2008) Herbert Marini et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Phytoestrogen-mediated inhibition of proliferation of the human T47D breast cancer cells depends on the ERα/ERβ ratio

(2008) A.M. Sotoca et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estrogen Receptors α and β as Determinants of Gene Expression: Influence of Ligand, Dose, and Chromatin Binding

(2008) Edmund C. Chang et al.   MOLECULAR ENDOCRINOLOGY

Conclusion that isoflavones exert estrogenic effects on breast tissue and may raise breast cancer risk unfounded

(2008) Mark Messina   MOLECULAR NUTRITION & FOOD RESEARCH

Influence of Cellular ERα/ERβ Ratio on the ERα-Agonist Induced Proliferation of Human T47D Breast Cancer Cells

(2008) Ana Maria Sotoca Covaleda et al.   TOXICOLOGICAL SCIENCES