HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer
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Title
HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 130, Issue 10, Pages 5074-5087
Publisher
American Society for Clinical Investigation
Online
2020-09-02
DOI
10.1172/jci137552
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Note: Only part of the references are listed.- Decylubiquinone suppresses breast cancer growth and metastasis by inhibiting angiogenesis via the ROS/p53/ BAI1 signaling pathway
- (2020) Jinghua Cao et al. ANGIOGENESIS
- Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration
- (2020) Mounia Beloueche-Babari et al. BRITISH JOURNAL OF CANCER
- HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis
- (2020) Yanling Niu et al. CANCER RESEARCH
- A Small Hypoxia Signature Predicted pCR Response to Bevacizumab in the Neoadjuvant GeparQuinto Breast Cancer Trial
- (2020) Thomas Karn et al. CLINICAL CANCER RESEARCH
- Ketogenic diets in medical oncology: a systematic review with focus on clinical outcomes
- (2020) Rainer J. Klement et al. MEDICAL ONCOLOGY
- Hypoxia Attenuates Trastuzumab Uptake and Trastuzumab-Emtansine (T-DM1) Cytotoxicity Through Redistribution of Phosphorylated Caveolin-1
- (2020) Vineesh Indira Chandran et al. MOLECULAR CANCER RESEARCH
- A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
- (2020) Maria Escala-Garcia et al. Nature Communications
- Dietary modifications for enhanced cancer therapy
- (2020) Naama Kanarek et al. NATURE
- Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells
- (2019) Angelika Bröer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Therapeutic impact of Nintedanib with paclitaxel and/or a PD-L1 antibody in preclinical models of orthotopic primary or metastatic triple negative breast cancer
- (2019) Elaine Reguera-Nuñez et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Hypoxic Radioresistance: Can ROS Be the Key to Overcome It?
- (2019) Hui Wang et al. Cancers
- Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer
- (2019) Luigi Formisano et al. Nature Communications
- The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression
- (2019) Biao Ma et al. Nature Communications
- Prognostic role of glycolysis for cancer outcome: evidence from 86 studies
- (2019) Min Yu et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting
- (2019) Mark R. Sullivan et al. Cell Metabolism
- Na+,HCO3− cotransporter NBCn1 accelerates breast carcinogenesis
- (2019) Ebbe Boedtkjer CANCER AND METASTASIS REVIEWS
- Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges
- (2019) John D. Martin et al. Annual Review of Physiology
- A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells
- (2019) Mam Y. Mboge et al. BIOCHEMICAL JOURNAL
- Development and radiosynthesis of the first 18 F-labeled inhibitor of monocarboxylate transporters (MCTs)
- (2019) Masoud Sadeghzadeh et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells
- (2019) Fei Chen et al. NATURE CELL BIOLOGY
- Targeting hypoxia-induced carbonic anhydrase IX enhances immune checkpoint blockade locally and systemically
- (2019) Shawn C Chafe et al. Cancer Immunology Research
- Metformin inhibits metastatic breast cancer progression and improves chemosensitivity by inducing vessel normalization via PDGF-B downregulation
- (2019) Ji-Chang Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer
- (2019) Matteo Morotti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Monocarboxylate transporters in cancer
- (2019) Valéry L. Payen et al. Molecular Metabolism
- A phase II study of cabozantinib alone or in combination with trastuzumab in breast cancer patients with brain metastases
- (2019) José Pablo Leone et al. BREAST CANCER RESEARCH AND TREATMENT
- Causes and Consequences of A Glutamine Induced Normoxic HIF1 Activity for the Tumor Metabolism
- (2019) Matthias Kappler et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hypoxia-reprogrammed tricarboxylic acid cycle promotes the growth of human breast tumorigenic cells
- (2019) Ke Tang et al. ONCOGENE
- Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes
- (2019) Megan A. Altemus et al. PLoS One
- Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer
- (2019) Diane M. Demas et al. Frontiers in Oncology
- Breast cancer statistics, 2019
- (2019) Carol E. DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Randomized Phase 0/I Trial of the Mitochondrial Inhibitor ME-344 or Placebo Added to Bevacizumab in Early HER2-Negative Breast Cancer
- (2019) Miguel Quintela-Fandino et al. CLINICAL CANCER RESEARCH
- Phase II randomised discontinuation trial of brivanib in patients with advanced solid tumours
- (2019) Robin L. Jones et al. EUROPEAN JOURNAL OF CANCER
- CAIX forms a transport metabolon with monocarboxylate transporters in human breast cancer cells
- (2019) Samantha Ames et al. ONCOGENE
- Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis
- (2019) Inês Godet et al. Nature Communications
- Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
- (2019) Michael J. Lukey et al. Cell Reports
- CAIX is a predictor of pathological complete response and is associated with higher survival in locally advanced breast cancer submitted to neoadjuvant chemotherapy
- (2019) Wilson Eduardo Furlan Matos Alves et al. BMC CANCER
- A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells
- (2019) Hee Chan Yoo et al. Cell Metabolism
- GDF15 mediates the effects of metformin on body weight and energy balance
- (2019) Anthony P. Coll et al. NATURE
- Expression of HIF-1α is related to a poor prognosis and tamoxifen resistance in contralateral breast cancer
- (2019) Annika Jögi et al. PLoS One
- FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer
- (2019) Xiaoyong Fu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metformin: The Answer to Cancer in a Flower? Current Knowledge and Future Prospects of Metformin as an Anti-Cancer Agent in Breast Cancer
- (2019) Samson Mathews Samuel et al. Biomolecules
- Consensus guidelines for the use and interpretation of angiogenesis assays
- (2018) Patrycja Nowak-Sliwinska et al. ANGIOGENESIS
- Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
- (2018) Debangshu Samanta et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Glucose-dependent growth arrest of leukemia cells by MCT1 inhibition: Feeding Warburg’s sweet tooth and blocking acid export as an anticancer strategy
- (2018) Aleksandra I. Pivovarova et al. BIOMEDICINE & PHARMACOTHERAPY
- Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways
- (2018) Michelle van Geldermalsen et al. BMC CANCER
- Targeting tumor-associated acidity in cancer immunotherapy
- (2018) Ruben Lacroix et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Advances in Hypoxia-Inducible Factor Biology
- (2018) Hani Choudhry et al. Cell Metabolism
- Molecular Mechanisms Linking Exercise to Cancer Prevention and Treatment
- (2018) Pernille Hojman et al. Cell Metabolism
- ZMYND8 acetylation mediates HIF-dependent breast cancer progression and metastasis
- (2018) Yan Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Breast Cancer Blood Flow and Metabolism on Dual-Acquisition18F-FDG PET: Correlation with Tumor Phenotype and Neoadjuvant Chemotherapy Response
- (2018) Olivier Humbert et al. JOURNAL OF NUCLEAR MEDICINE
- OUP accepted manuscript
- (2018) JOURNAL OF NUTRITION
- Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models
- (2018) Michael L Schulte et al. NATURE MEDICINE
- Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa
- (2018) Kabir A. Khan et al. Nature Reviews Clinical Oncology
- Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis
- (2018) Huichun Liang et al. ONCOGENE
- Synergistic anti-angiogenic treatment effects by dual FGFR1 and VEGFR1 inhibition in FGFR1-amplified breast cancer
- (2018) Kristina Golfmann et al. ONCOGENE
- Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2
- (2018) Joao Incio et al. Science Translational Medicine
- Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft
- (2018) Santosh K. Bharti et al. Oncotarget
- The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells
- (2018) Samantha Ames et al. Oncotarget
- Metformin-induced caveolin-1 expression promotes T-DM1 drug efficacy in breast cancer cells
- (2018) Yuan-Chiang Chung et al. Scientific Reports
- DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer
- (2018) Simon Peter Gampenrieder et al. Theranostics
- Targeting SLC25A10 alleviates improved antioxidant capacity and associated radioresistance of cancer cells induced by chronic-cycling hypoxia
- (2018) Julian Hlouschek et al. CANCER LETTERS
- Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer
- (2018) Simon R. Lord et al. Cell Metabolism
- Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-Regulated Genes
- (2018) I. Chae Ye et al. MOLECULAR CANCER RESEARCH
- LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response
- (2018) Inna Serganova et al. PLoS One
- Associations of angiogenesis-related proteins with specific prognostic factors, breast cancer subtypes and survival outcome in early-stage breast cancer patients. A Hellenic Cooperative Oncology Group (HeCOG) trial
- (2018) Anna Goussia et al. PLoS One
- BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
- (2018) Andrew G. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pre- and post-operative anti-PD-L1 plus anti-angiogenic therapies in mouse breast or renal cancer models of micro- or macro-metastatic disease
- (2018) Florence T. H. Wu et al. BRITISH JOURNAL OF CANCER
- The clinicopathological and prognostic value of hypoxia-inducible factor-2α in cancer patients: a systematic review and meta-analysis
- (2018) Deqing Luo et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin
- (2018) James A Smythies et al. EMBO REPORTS
- Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1–NDRG1 axis in both PR-positive and -negative breast cancer cells
- (2018) Mukul Godbole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Challenges facing antiangiogenesis therapy: The significant role of hypoxia-inducible factor and MET in development of resistance to anti-vascular endothelial growth factor-targeted therapies
- (2018) Ali Mahdi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Diffuse optical spectroscopy for monitoring the responses of patients with breast cancer to neoadjuvant chemotherapy
- (2018) Yong Hong Liu et al. MEDICINE
- Hypoxia-inducible factor 1-alpha expression correlates with response to neoadjuvant chemotherapy in women with breast cancer
- (2018) Caiyun Nie et al. MEDICINE
- Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4
- (2018) Ryan Kolb et al. ONCOGENE
- Collagen prolyl 4-hydroxylase 1 is essential for HIF-1α stabilization and TNBC chemoresistance
- (2018) Gaofeng Xiong et al. Nature Communications
- Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells
- (2018) Don Benjamin et al. Cell Reports
- Bevacizumab plus paclitaxel versus placebo plus paclitaxel as first-line therapy for HER2-negative metastatic breast cancer (MERiDiAN): A double-blind placebo-controlled randomised phase III trial with prospective biomarker evaluation
- (2017) David Miles et al. EUROPEAN JOURNAL OF CANCER
- The accuracy of 18F-FDG PET/CT in predicting the pathological response to neoadjuvant chemotherapy in patients with breast cancer: a meta-analysis and systematic review
- (2017) Fangfang Tian et al. EUROPEAN RADIOLOGY
- Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)
- (2017) Ganesha Rai et al. JOURNAL OF MEDICINAL CHEMISTRY
- In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer
- (2017) Basel Abu-Jamous et al. Molecular Cancer
- Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
- (2017) Lin Tian et al. NATURE
- Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade
- (2017) Martina Schmittnaegel et al. Science Translational Medicine
- Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation
- (2017) Elizabeth Allen et al. Science Translational Medicine
- Hypoxia-related biological markers as predictors of epirubicin-based treatment responsiveness and resistance in locally advanced breast cancer
- (2017) Manuela Milani et al. Oncotarget
- The prognostic value of GLUT1 in cancers: a systematic review and meta-analysis
- (2017) Min Yu et al. Oncotarget
- The Linkage between Breast Cancer, Hypoxia, and Adipose Tissue
- (2017) Linda K. Rausch et al. Frontiers in Oncology
- Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition
- (2017) Michael Lampa et al. PLoS One
- The hypoxic tumor microenvironment: A driving force for breast cancer progression
- (2016) Gregg L. Semenza BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Predictive role of the overexpression for CXCR4, C-Met, and VEGF-C among breast cancer patients: A meta-analysis
- (2016) Fang Wang et al. BREAST
- PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis
- (2016) D. Samanta et al. CANCER RESEARCH
- Predicting Responses to Neoadjuvant Chemotherapy in Breast Cancer: ACRIN 6691 Trial of Diffuse Optical Spectroscopic Imaging
- (2016) B. J. Tromberg et al. CANCER RESEARCH
- Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target
- (2016) Geoffrey Grandjean et al. CANCER RESEARCH
- Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
- (2016) Kimberly J. Briggs et al. CELL
- Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
- (2016) Gregg L Semenza EMBO JOURNAL
- Antiangiogenic therapy in oncology: current status and future directions
- (2016) Gordon C Jayson et al. LANCET
- ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models
- (2016) Danielle L. Peacock Brooks et al. Molecular Cancer
- Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases
- (2016) Sophia Frentzas et al. NATURE MEDICINE
- Phase II and Biomarker Study of Cabozantinib in Metastatic Triple‐Negative Breast Cancer Patients
- (2016) Sara M. Tolaney et al. ONCOLOGIST
- Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer
- (2016) Caroline Wigerup et al. PHARMACOLOGY & THERAPEUTICS
- Prognostic Significance of High VEGF-C Expression for Patients with Breast Cancer: An Update Meta Analysis
- (2016) Zhiqiao Zhang et al. PLoS One
- A hypoxic signature marks tumors formed by disseminated tumor cells in the BALB-neuT mammary cancer model
- (2016) Aichi Msaki et al. Oncotarget
- Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells
- (2016) Jerry H. Fuady et al. Oncotarget
- MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4
- (2016) Candice Sun Hong et al. Cell Reports
- Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment
- (2016) Shaveta Mehta et al. EBioMedicine
- Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis
- (2016) Simon J. A. van Kuijk et al. Frontiers in Oncology
- Molecular imaging as a tool to investigate heterogeneity of advanced HER2-positive breast cancer and to predict patient outcome under trastuzumab emtansine (T-DM1): the ZEPHIR trial
- (2015) G. Gebhart et al. ANNALS OF ONCOLOGY
- The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study
- (2015) Stefanie de Groot et al. BMC CANCER
- The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor
- (2015) Cara J. Valvona et al. BRAIN PATHOLOGY
- Trebananib (AMG 386) plus weekly paclitaxel with or without bevacizumab as first-line therapy for HER2-negative locally recurrent or metastatic breast cancer: A phase 2 randomized study
- (2015) Véronique Diéras et al. BREAST
- Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies
- (2015) Young Joo Jeon et al. CANCER CELL
- Prognostic significance of c-Met in breast cancer: a meta-analysis of 6010 cases
- (2015) Shunchao Yan et al. Diagnostic Pathology
- EglN2 associates with the NRF1‐PGC1α complex and controls mitochondrial function in breast cancer
- (2015) Jing Zhang et al. EMBO JOURNAL
- A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors
- (2015) Quincy Siu-Chung Chu et al. INVESTIGATIONAL NEW DRUGS
- Cross-talk between ER and HER2 regulates c-MYC-mediated glutamine metabolism in aromatase inhibitor resistant breast cancer cells
- (2015) Zhike Chen et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer
- (2015) M van Geldermalsen et al. ONCOGENE
- Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
- (2015) Haiquan Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer
- (2015) Jun Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function
- (2015) Somayeh Jamali et al. Scientific Reports
- Tumor factors predictive of response to hypofractionated radiotherapy in a randomized trial following breast conserving therapy
- (2014) A. L. Bane et al. ANNALS OF ONCOLOGY
- The Clinical Importance of Assessing Tumor Hypoxia: Relationship of Tumor Hypoxia to Prognosis and Therapeutic Opportunities
- (2014) Joseph C. Walsh et al. ANTIOXIDANTS & REDOX SIGNALING
- Prospective neoadjuvant analysis of PET imaging and mechanisms of resistance to Trastuzumab shows role of HIF1 and autophagy
- (2014) M I Koukourakis et al. BRITISH JOURNAL OF CANCER
- Targeting of two aspects of metabolism in breast cancer treatment
- (2014) Bevan P Gang et al. CANCER BIOLOGY & THERAPY
- ERGO: A pilot study of ketogenic diet in recurrent glioblastoma
- (2014) JOHANNES RIEGER et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Repositioning Proton Pump Inhibitors as Anticancer Drugs by Targeting the Thioesterase Domain of Human Fatty Acid Synthase
- (2014) Valerie E. Fako et al. JOURNAL OF MEDICINAL CHEMISTRY
- Use of [18F]-FDG PET to predict response to neoadjuvant trastuzumab and docetaxel in patients with HER2-positive breast cancer, and addition of bevacizumab to neoadjuvant trastuzumab and docetaxel in [18F]-FDG PET-predicted non-responders (AVATAXHER): an open-label, randomised phase 2 trial
- (2014) Bruno Coudert et al. LANCET ONCOLOGY
- XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway
- (2014) Xi Chen et al. NATURE
- Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
- (2014) T. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells
- (2014) Debangshu Samanta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
- (2014) J. Ye et al. Cancer Discovery
- Pan-genomic binding of hypoxia-inducible transcription factors
- (2013) Johannes Schödel et al. BIOLOGICAL CHEMISTRY
- The potential of hypoxia markers as target for breast molecular imaging – a systematic review and meta-analysis of human marker expression
- (2013) Arthur Adams et al. BMC CANCER
- A meta-analysis of gene expression-based biomarkers predicting outcome after tamoxifen treatment in breast cancer
- (2013) Zsuzsanna Mihály et al. BREAST CANCER RESEARCH AND TREATMENT
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- 18F-FDG PET/CT for Early Prediction of Response to Neoadjuvant Lapatinib, Trastuzumab, and Their Combination in HER2-Positive Breast Cancer: Results from Neo-ALTTO
- (2013) G. Gebhart et al. JOURNAL OF NUCLEAR MEDICINE
- 18F-Fluoromisonidazole PET/CT: A Potential Tool for Predicting Primary Endocrine Therapy Resistance in Breast Cancer
- (2013) J. Cheng et al. JOURNAL OF NUCLEAR MEDICINE
- HIF-1α Overexpression in Ductal Carcinoma In Situ of the Breast in BRCA1 and BRCA2 Mutation Carriers
- (2013) Petra van der Groep et al. PLoS One
- Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression
- (2012) Jun Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- The Tyrosine Kinase Inhibitor E-3810 Combined with Paclitaxel Inhibits the Growth of Advanced-Stage Triple-Negative Breast Cancer Xenografts
- (2012) E. Bello et al. MOLECULAR CANCER THERAPEUTICS
- HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
- (2012) Ainara Elorza et al. MOLECULAR CELL
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Metabolism of [U-13C]glucose in human brain tumorsin vivo
- (2012) Elizabeth A. Maher et al. NMR IN BIOMEDICINE
- Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer
- (2012) G Sutendra et al. ONCOGENE
- Metabolism-Related Proteins Are Differentially Expressed according to the Molecular Subtype of Invasive Breast Cancer Defined by Surrogate Immunohistochemistry
- (2012) Junjeong Choi et al. PATHOBIOLOGY
- Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells
- (2011) Yasuki Higashimura et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Noninvasive Detection of Breast Cancer Lymph Node Metastasis Using Carbonic Anhydrases IX and XII Targeted Imaging Probes
- (2011) N. K. Tafreshi et al. CLINICAL CANCER RESEARCH
- Molecular mechanisms and clinical applications of angiogenesis
- (2011) Peter Carmeliet et al. NATURE
- HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
- (2011) H Zhang et al. ONCOGENE
- Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer
- (2010) Carlos H. Barrios et al. BREAST CANCER RESEARCH AND TREATMENT
- Advances in Targeting Src in the Treatment of Breast Cancer and Other Solid Malignancies
- (2010) E. L. Mayer et al. CLINICAL CANCER RESEARCH
- 2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer
- (2008) S L C Tagg et al. BRITISH JOURNAL OF CANCER
- Hypoxia-Inducible Factor-2 Correlates to Distant Recurrence and Poor Outcome in Invasive Breast Cancer
- (2008) K. Helczynska et al. CANCER RESEARCH
- Phosphorylated ERα, HIF-1α, and MAPK Signaling As Predictors of Primary Endocrine Treatment Response and Resistance in Patients With Breast Cancer
- (2008) Daniele Generali et al. JOURNAL OF CLINICAL ONCOLOGY
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