Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 50, Pages E5429-E5438
Publisher
Proceedings of the National Academy of Sciences
Online
2014-12-02
DOI
10.1073/pnas.1421438111
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metastatic Stem Cells: Sources, Niches, and Vital Pathways
- (2014) Thordur Oskarsson et al. Cell Stem Cell
- Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
- (2013) Gregg L. Semenza Annual Review of Pathology-Mechanisms of Disease
- Tumor Cells Upregulate Normoxic HIF-1 in Response to Doxorubicin
- (2013) Y. Cao et al. CANCER RESEARCH
- Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8
- (2013) Z. C. Hartman et al. CANCER RESEARCH
- Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer
- (2013) DG Tiezzi et al. Clinics
- Role of hypoxia-inducible factors in breast cancer metastasis
- (2013) Daniele M Gilkes et al. Future Oncology
- TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer
- (2013) Neil E. Bhola et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer
- (2013) Lisha Xiang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia
- (2013) Piotr Przanowski et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- TLR4 Is a Novel Determinant of the Response to Paclitaxel in Breast Cancer
- (2013) S. Rajput et al. MOLECULAR CANCER THERAPEUTICS
- Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells
- (2013) M F Kendellen et al. ONCOGENE
- A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
- (2012) S. K. Chia et al. CLINICAL CANCER RESEARCH
- Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
- (2012) Carmen Chak-Lui Wong et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A
- (2012) I. Mimura et al. MOLECULAR AND CELLULAR BIOLOGY
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- The UCSC Cancer Genomics Browser: update 2013
- (2012) Mary Goldman et al. NUCLEIC ACIDS RESEARCH
- Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
- (2012) Nanduri R. Prabhakar et al. PHYSIOLOGICAL REVIEWS
- Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
- (2012) S. J. Conley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- An increase in cancer stem cell population after primary systemic therapy is a poor prognostic factor in breast cancer
- (2011) H E Lee et al. BRITISH JOURNAL OF CANCER
- Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
- (2011) Nadine Rohwer et al. DRUG RESISTANCE UPDATES
- Heterogeneity in breast cancer
- (2011) Kornelia Polyak JOURNAL OF CLINICAL INVESTIGATION
- The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors
- (2011) Lauren L.C. Marotta et al. JOURNAL OF CLINICAL INVESTIGATION
- Insight into the heterogeneity of breast cancer through next-generation sequencing
- (2011) Hege G. Russnes et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
- (2011) H Zhang et al. ONCOGENE
- GOBO: Gene Expression-Based Outcome for Breast Cancer Online
- (2011) Markus Ringnér et al. PLoS One
- Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
- (2011) D. Iliopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
- (2010) F M Buffa et al. BRITISH JOURNAL OF CANCER
- Hypoxia inducible factors in cancer stem cells
- (2010) J M Heddleston et al. BRITISH JOURNAL OF CANCER
- Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1α
- (2010) Sreenivasulu Chintala et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
- (2010) Christophe Ginestier et al. JOURNAL OF CLINICAL INVESTIGATION
- Triple-Negative Breast Cancer
- (2010) William D. Foulkes et al. NEW ENGLAND JOURNAL OF MEDICINE
- An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
- (2009) Balazs Györffy et al. BREAST CANCER RESEARCH AND TREATMENT
- Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
- (2009) Emmanuelle Charafe-Jauffret et al. CANCER RESEARCH
- Association of Breast Cancer Stem Cells Identified by Aldehyde Dehydrogenase 1 Expression with Resistance to Sequential Paclitaxel and Epirubicin-Based Chemotherapy for Breast Cancers
- (2009) T. Tanei et al. CLINICAL CANCER RESEARCH
- Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes
- (2009) Joel S. Parker et al. JOURNAL OF CLINICAL ONCOLOGY
- Histological and molecular types of breast cancer: is there a unifying taxonomy?
- (2009) Britta Weigelt et al. Nature Reviews Clinical Oncology
- Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
- (2009) C. J. Creighton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
- (2009) K. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy
- (2008) X. Li et al. JNCI-Journal of the National Cancer Institute
- Digoxin and other cardiac glycosides inhibit HIF-1 synthesis and block tumor growth
- (2008) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search