Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis

Protective Effect of Ginsenoside Rg1 on Oxidative Damage Induced by Hydrogen Peroxide in Chicken Splenic Lymphocytes

(2019) Shicheng Bi et al.   Oxidative Medicine and Cellular Longevity

Dietary DHA/EPA supplementation ameliorates diabetic nephropathy by protecting from distal tubular cell damage

(2019) Marija Vitlov Uljević et al.   CELL AND TISSUE RESEARCH

miR‐124a enhances therapeutic effects of bone marrow stromal cells transplant on diabetic nephropathy‐related epithelial‐to‐mesenchymal transition and fibrosis

(2019) Xiaojun Cai et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

From podocyte biology to novel cures for glomerular disease

(2019) Elena Torban et al.   KIDNEY INTERNATIONAL

Calpain silencing alleviates myocardial ischemia-reperfusion injury through the NLRP3/ASC/Caspase-1 axis in mice

(2019) Rong-Chuan Yue et al.   LIFE SCIENCES

TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease

(2019) Youliang Wang et al.   Frontiers in Endocrinology

Calpain-10 drives podocyte apoptosis and renal injury in diabetic nephropathy

(2019) Tao Wang et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Ginsenoside Rg1 inhibits apoptosis by increasing autophagy via the AMPK/mTOR signaling in serum deprivation macrophages

(2018) Ping Yang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

OUP accepted manuscript

(2018)   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Rapamycin Reduces Podocyte Apoptosis and is Involved in Autophagy and mTOR/ P70S6K/4EBP1 Signaling

(2018) Juan Jin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy

(2018) Nianxiu Tian et al.   Drug Design Development and Therapy

Hyperglycemia induces inflammatory mediators in the human chorionic villous

(2018) Simone Corrêa-Silva et al.   CYTOKINE

Astragaloside IV represses high glucose-induced mesangial cells activation by enhancing autophagy via SIRT1 deacetylation of NF-κB P65 subunit

(2018) Xiaolei Wang et al.   Drug Design Development and Therapy

Combination of Ginsenoside Rg1 and Astragaloside IV reduces oxidative stress and inhibits TGF-β1/Smads signaling cascade on renal fibrosis in rats with diabetic nephropathy

(2018) Na Du et al.   Drug Design Development and Therapy

Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B

(2018) Tomohisa Hatta et al.   Scientific Reports

Delayed oseltamivir plus sirolimus treatment attenuates H1N1 virus-induced severe lung injury correlated with repressed NLRP3 inflammasome activation and inflammatory cell infiltration

(2018) Xuehong Jia et al.   PLoS Pathogens

Metabolic regulation of NLRP3

(2017) Mark M. Hughes et al.   IMMUNOLOGICAL REVIEWS

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Protection by mTOR Inhibition on Zymosan-Induced Systemic Inflammatory Response and Oxidative/Nitrosative Stress: Contribution of mTOR/MEK1/ERK1/2/IKKβ/IκB-α/NF-κB Signalling Pathway

(2017) Seyhan Sahan-Firat et al.   INFLAMMATION

Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor‑κB pathway and inhibition of inflammasome activation in alcoholic hepatitis

(2017) Jiajun Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1β production via suppressing the NF-κB pathway and ROS production

(2017) Xin Yu et al.   JOURNAL OF HEPATOLOGY

Ginsenoside Rg1 protects against sepsis-associated encephalopathy through beclin 1–independent autophagy in mice

(2017) Yinjiao Li et al.   JOURNAL OF SURGICAL RESEARCH

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy

(2017) Hong Yi et al.   Cell Death & Disease

Apelin involved in progression of diabetic nephropathy by inhibiting autophagy in podocytes

(2017) Yu Liu et al.   Cell Death & Disease

Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation

(2017) Jesus Cosin-Roger et al.   Nature Communications

The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling

(2017) Mee-Sup Yoon   Nutrients

Ginsenoside Rg1 Attenuates Cigarette Smoke-Induced Pulmonary Epithelial-Mesenchymal Transition via Inhibition of the TGF-β1/Smad Pathway

(2017) Sibin Guan et al.   Biomed Research International

ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication

(2017) Masato Kitazawa et al.   PLoS One

p65 down-regulates DEPTOR expression in response to LPS stimulation in hepatocytes

(2016) Xiaoling Yu et al.   GENE

Ginsenoside Rg1 ameliorates diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress-induced apoptosis in a streptozotocin-induced diabetes rat model

(2016) Haitao Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nephroprotective Effects of Metformin in Diabetic Nephropathy

(2016) Sreenithya Ravindran et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protective effects of ginsenoside Rg1 on intestinal ischemia/reperfusion injury-induced oxidative stress and apoptosis via activation of the Wnt/β-catenin pathway

(2016) Guo Zu et al.   Scientific Reports

Emerging role of podocyte autophagy in the progression of diabetic nephropathy

(2015) Mako Yasuda-Yamahara et al.   Autophagy

Ginsenoside Rg1 ameliorates oxidative stress and myocardial apoptosis in streptozotocin-induced diabetic rats

(2015) Hai-tao Yu et al.   Journal of Zhejiang University-SCIENCE B

Neuroprotective effects of ginsenoside Rg1-induced neural stem cell transplantation on hypoxic-ischemic encephalopathy

(2015) Sha-li Wang et al.   Neural Regeneration Research

Astragaloside IV attenuates proteinuria in streptozotocin-induced diabetic nephropathy via the inhibition of endoplasmic reticulum stress

(2015) Zeng Si Wang et al.   BMC Nephrology

Ginsenoside Rg1 protects mouse podocytes from aldosterone-induced injury in vitro

(2014) Nan Mao et al.   ACTA PHARMACOLOGICA SINICA

TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia/reperfusion injury

(2014) Yi Liu et al.   BASIC RESEARCH IN CARDIOLOGY

NF-κB signaling inhibition and anticancer activities of LLDT-246 on human colorectal cancer HCT-116 cells in vitro

(2014) Meng Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Crosstalk between protective autophagy and NF-κB signal in high glucose-induced podocytes

(2014) Miaomiao Wei et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Crosstalk between apoptosis, necrosis and autophagy

(2013) Vassiliki Nikoletopoulou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Extensive Podocyte Loss Triggers a Rapid Parietal Epithelial Cell Response

(2013) S. Hakroush et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Combined Angiotensin Inhibition for the Treatment of Diabetic Nephropathy

(2013) Linda F. Fried et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy is required for the activation of NFκB

(2012) Alfredo Criollo et al.   CELL CYCLE

Activation of Nod-Like Receptor Protein 3 Inflammasomes Turns on Podocyte Injury and Glomerular Sclerosis in Hyperhomocysteinemia

(2012) Chun Zhang et al.   HYPERTENSION

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

(2011) Ken Inoki et al.   JOURNAL OF CLINICAL INVESTIGATION

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Mechanisms of Podocyte Injury in Diabetes: Role of Cytochrome P450 and NADPH Oxidases

(2009) A. A. Eid et al.   DIABETES

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA