Ginsenoside Rg1 Attenuates Cigarette Smoke-Induced Pulmonary Epithelial-Mesenchymal Transition via Inhibition of the TGF-β1/Smad Pathway

Paraquat induce pulmonary epithelial–mesenchymal transition through transforming growth factor-β1-dependent mechanism

(2016) Linshen Xie et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Ginsenoside Rg1 exerts a protective effect against Aβ25–35-induced toxicity in primary cultured rat cortical neurons through the NF-κB/NO pathway

(2016) JIAYING WU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Integrated long non-coding RNA analyses identify novel regulators of epithelial-mesenchymal transition in the mouse model of pulmonary fibrosis

(2016) Hao Sun et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Down-regulation of microRNAs of themiR-200family and up-regulation of Snail and Slug in inflammatory bowel diseases - hallmark of epithelial−mesenchymal transition

(2016) Nina Zidar et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Novel anti-cancer agent myrtucommulone-A and thymoquinone abrogate epithelial–mesenchymal transition in cancer cells mainly through the inhibition of PI3K/AKT signalling axis

(2016) Banu Iskender et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mechanism of ginsenoside Rg1 renal protection in a mouse model ofd-galactose-induced subacute damage

(2016) Yanling Fan et al.   PHARMACEUTICAL BIOLOGY

AURKA induces EMT by regulating histone modification through Wnt/β-catenin and PI3K/Akt signaling pathway in gastric cancer

(2016) Xi Liu et al.   Oncotarget

Dexamethasone Inhibits TGF-β1–Induced Cell Migration by Regulating the ERK and AKT Pathways in Human Colon Cancer Cells Via CYR61

(2016) Sanghoon Han et al.   Cancer Research and Treatment

A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease

(2016) Naijing Li et al.   Journal of Ginseng Research

Effects of geniposide on hepatocytes undergoing epithelial–mesenchymal transition in hepatic fibrosis by targeting TGFβ/Smad and ERK-MAPK signaling pathways

(2015) Ji-Hyun Park et al.   BIOCHIMIE

CXCR2/CXCL5 axis contributes to epithelial–mesenchymal transition of HCC cells through activating PI3K/Akt/GSK-3β/Snail signaling

(2015) Shao-Lai Zhou et al.   CANCER LETTERS

Ginsenoside Rg1 improves lipopolysaccharide-induced acute lung injury by inhibiting inflammatory responses and modulating infiltration of M2 macrophages

(2015) Suhong Bao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Panax ginseng aqueous extract prevents pneumococcal sepsis in vivo by potentiating cell survival and diminishing inflammation

(2015) Cuong Thach Nguyen et al.   PHYTOMEDICINE

Mesenchymal stem cells alleviate airway inflammation and emphysema in COPD through down-regulation of cyclooxygenase-2 via p38 and ERK MAPK pathways

(2015) Wen Gu et al.   Scientific Reports

Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction

(2015) Malik Mahmood et al.   International Journal of Chronic Obstructive Pulmonary Disease

Therapeutic potential of Panax ginseng and ginsenosides in the treatment of chronic obstructive pulmonary disease

(2014) J.L. Shergis et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Airway and Lung Remodelling in Chronic Pulmonary Obstructive Disease: A Role for Muscarinic Receptor Antagonists?

(2014) Michael Roth   DRUGS

Treatment with ginseng total saponins improves the neurorestoration of rat after traumatic brain injury

(2014) Bao-Ying Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ginsenoside Rg1 attenuates invasion and migration by inhibiting transforming growth factor-β1-induced epithelial to mesenchymal transition in HepG2 cells

(2014) MEILING YU et al.   Molecular Medicine Reports

Evidence of TGF-β1 mediated epithelial-mesenchymal transition in immortalized benign prostatic hyperplasia cells

(2014) Shuai Hu et al.   MOLECULAR MEMBRANE BIOLOGY

TGF-β1/Smad Signaling Pathway Regulates Epithelial-to-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma: In Vitro and Clinical Analyses of Cell Lines and Nomadic Kazakh Patients from Northwest Xinjiang, China

(2014) Lijuan Pang et al.   PLoS One

Systems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthma

(2014) Talha Ijaz et al.   World Allergy Organization Journal

Novel therapeutic strategies for lung disorders associated with airway remodelling and fibrosis

(2013) Simon G. Royce et al.   PHARMACOLOGY & THERAPEUTICS

Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease

(2013) Sukhwinder Singh Sohal et al.   Expert Review of Respiratory Medicine

The Critical Role of TAK1 in Accentuated Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis after Lung Transplantation

(2012) Aaron Gardner et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibitory effect of ginsenoside Rg1 on extracellular matrix production via extracellular signal-regulated protein kinase/activator protein 1 pathway in nasal polyp-derived fibroblasts

(2012) Jung-Sun Cho et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Ginseng, the 'Immunity Boost': The Effects of Panax ginseng on Immune System

(2012) Soo-Won Kang et al.   Journal of Ginseng Research

Pharmacokinetic, tissue distribution and excretion of ginsenoside-Rd in rodents

(2011) Dong Sun et al.   PHYTOMEDICINE

The inhibitory effect of ginsan on TGF-β mediated fibrotic process

(2010) Ji-Yeon Ahn et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Anti-fatigue activity of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer

(2010) Jia Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease

(2010) Sukhwinder S. SOHAL et al.   RESPIROLOGY

Induction of Epithelial–Mesenchymal Transition in Primary Airway Epithelial Cells from Patients with Asthma by Transforming Growth Factor-β1

(2009) Tillie-Louise Hackett et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ginsenoside Rg1, a major active component isolated from Panax notoginseng, restrains tubular epithelial to myofibroblast transition in vitro

(2008) Xi-Sheng Xie et al.   JOURNAL OF ETHNOPHARMACOLOGY