LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy

Atorvastatin suppresses NLRP3 inflammasome activation via TLR4/MyD88/NF-κB signaling in PMA-stimulated THP-1 monocytes

(2016) Fanqi Kong et al.   BIOMEDICINE & PHARMACOTHERAPY

Genome-wide identification of human- and primate-specific core promoter short tandem repeats

(2016) A. Bushehri et al.   GENE

Danshen injection ameliorates STZ-induced diabetic nephropathy in association with suppression of oxidative stress, pro-inflammatory factors and fibrosis

(2016) Linhao Xu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Nuclear Protein IκBζ Forms a Transcriptionally Active Complex with Nuclear Factor-κB (NF-κB) p50 and theLcn2Promoter via the N- and C-terminal Ankyrin Repeat Motifs

(2016) Akira Kohda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cepharanthine and Piperine ameliorate diabetic nephropathy in rats: role of NF-κB and NLRP3 inflammasome

(2016) Yara A. Samra et al.   LIFE SCIENCES

miR-451 suppresses the NF-kappaB-mediated proinflammatory molecules expression through inhibiting LMP7 in diabetic nephropathy

(2016) Yan Sun et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A novel long non-coding RNA CYP4B1-PS1-001 regulates proliferation and fibrosis in diabetic nephropathy

(2016) Min Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

SN50, a Cell-Permeable Inhibitor of Nuclear Factor-κB, Attenuates Ventilator-Induced Lung Injury in an Isolated and Perfused Rat Lung Model

(2016) Chih-Feng Chian et al.   SHOCK

MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome

(2016) Xixi Zhang et al.   Cell Reports

Long non-coding MIAT mediates high glucose-induced renal tubular epithelial injury

(2015) Ling Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Cytoplasmic NF-κB Interacting Long Noncoding RNA Blocks IκB Phosphorylation and Suppresses Breast Cancer Metastasis

(2015) Bodu Liu et al.   CANCER CELL

BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathway

(2015) Sambasiva Rao Kolati et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation

(2015) Yinquan Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High glucose induces rat mesangial cells proliferation and MCP-1 expression via ROS-mediated activation of NF-κB pathway, which is inhibited by eleutheroside E

(2015) Xiuqin Yang et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Revisiting inflammation in diabetic nephropathy: the role of the Nlrp3 inflammasome in glomerular resident cells

(2015) Norihiko Sakai et al.   KIDNEY INTERNATIONAL

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

(2015) Khurrum Shahzad et al.   KIDNEY INTERNATIONAL

Relevance of TNF-α in the context of other inflammatory cytokines in the progression of diabetic nephropathy

(2015) Lin Sun et al.   KIDNEY INTERNATIONAL

The function of miR-199a-5p/Klotho regulating TLR4/NF-κB p65/NGAL pathways in rat mesangial cells cultured with high glucose and the mechanism

(2015) Can Wu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Long Noncoding RNA Arid2-IR Is a Novel Therapeutic Target for Renal Inflammation

(2015) Qin Zhou et al.   MOLECULAR THERAPY

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

(2015) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Inflammatory Cytokines in Diabetic Nephropathy

(2015) Javier Donate-Correa et al.   Journal of Diabetes Research

Thioredoxin-interacting protein mediates NALP3 inflammasome activation in podocytes during diabetic nephropathy

(2014) Pan Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inflammatory signaling regulates hematopoietic stem and progenitor cell emergence in vertebrates

(2014) Q. He et al.   BLOOD

NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

(2014) Beibei Luo et al.   PLoS One

Pathogenic role of lncRNA-MALAT1 in endothelial cell dysfunction in diabetes mellitus

(2014) J-Y Liu et al.   Cell Death & Disease

Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis

(2013) Shun-Min Yang et al.   DIABETOLOGIA

New Therapies for Diabetic Kidney Disease

(2013) Jonathan Himmelfarb et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of MicroRNA 1207-5P and Its Host Gene, the Long Non-Coding RNA Pvt1, as Mediators of Extracellular Matrix Accumulation in the Kidney: Implications for Diabetic Nephropathy

(2013) M. Lucrecia Alvarez et al.   PLoS One

Inhibitor of nuclear factor-κB, SN50, attenuates lipopolysaccharide-induced lung injury in an isolated and perfused rat lung model

(2013) Chih-Feng Chian et al.   Translational Research

The DNA demethylating agent decitabine activates the TRAIL pathway and induces apoptosis in acute myeloid leukemia

(2012) Matías Soncini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inflammation and the pathogenesis of diabetic nephropathy

(2012) Jun Wada et al.   CLINICAL SCIENCE

Specific-site methylation of tumour suppressor ANKRD11 in breast cancer

(2012) Sue Ping Lim et al.   EUROPEAN JOURNAL OF CANCER

TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

(2012) Yu Qiao et al.   FEBS LETTERS

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

NF-κB regulation: lessons from structures

(2012) Gourisankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

MicroRNAs miR-125a and miR-125b constitutively activate the NF- B pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)

(2012) S.-W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription factor binding predictions using TRAP for the analysis of ChIP-seq data and regulatory SNPs

(2011) Morgane Thomas-Chollier et al.   Nature Protocols

Functional Characterization of the Plasmacytoma Variant Translocation 1 Gene (PVT1) in Diabetic Nephropathy

(2011) M. Lucrecia Alvarez et al.   PLoS One

Non-coding RNAs: Meet thy masters

(2010) Fabrício F. Costa   BIOESSAYS

Relationship between Oxidative Stress and Inflammatory Cytokines in Diabetic Nephropathy

(2010) Ahmed A. Elmarakby et al.   Cardiovascular Therapeutics

Transcribed dark matter: meaning or myth?

(2010) C. P. Ponting et al.   HUMAN MOLECULAR GENETICS

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

Functional impact of sequence variation in the promoter region ofTGFB1

(2009) Jasmine Healy et al.   INTERNATIONAL JOURNAL OF CANCER

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Long intronic noncoding RNA transcription: Expression noise or expression choice?

(2008) Rodrigo Louro et al.   GENOMICS