Advances and novel developments in molecular allergology

Food allergy immunotherapy: OIT and EPIT

(2020) Edwin H. Kim et al.   ALLERGY

The Role of Eosinophils in Immunotherapy

(2020) Joseph Cafone et al.   CURRENT ALLERGY AND ASTHMA REPORTS

The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab

(2020) Pascal Gasser et al.   Nature Communications

A WAO — ARIA — GA2LEN consensus document on molecular-based allergy diagnosis (PAMD@): Update 2020

(2020) Ignacio J. Ansotegui et al.   World Allergy Organization Journal

Chronic allergen exposure drives accumulation of long-lived IgE plasma cells in the bone marrow, giving rise to serological memory

(2020) Seblewongel Asrat et al.   Science Immunology

Origins and clonal convergence of gastrointestinal IgE+ B cells in human peanut allergy

(2020) Ramona A. Hoh et al.   Science Immunology

iTRAQ‐based proteomic analysis reveals potential serum biomarkers of allergic and non‐allergic asthma

(2020) Juan José Nieto‐Fontarigo et al.   ALLERGY

Past, present, and future of anti‐IgE biologics

(2020) Pascal Guntern et al.   ALLERGY

IgE-blocking antibodies following SLIT with recombinant Mal d 1 accord with improved apple allergy

(2020) Gabriela Sánchez Acosta et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Biomarkers of severity and threshold of allergic reactions during oral peanut challenges

(2020) Alexandra F. Santos et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

EAACI Allergen Immunotherapy User's Guide

(2020) Montserrat Alvaro‐Lozano et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

The functional biology of peanut allergens and possible links to their allergenicity

(2019) Peggy Ozias-Akins et al.   ALLERGY

Crystal structure of the dog allergen Can f 6 and structure-based implications of its cross-reactivity with the cat allergen Fel d 4

(2019) Kenji Yamamoto et al.   Scientific Reports

Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid

(2019) Hideaki Morita et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Nanoallergen platform for detection of platin drug allergies

(2019) Peter E. Deak et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Gender aspects in food allergy

(2019) Isabella Pali-Schöll et al.   Current Opinion in Allergy and Clinical Immunology

Sublingual immunotherapy with recombinant Mal d 1 downregulates the allergen‐specific Th2 response

(2019) Claudia Kitzmüller et al.   ALLERGY

Identification of an Antigenic Determinant of Clavulanic Acid Responsible for IgE-mediated Reactions

(2019) Nekane Barbero et al.   ALLERGY

DNA methylation and allergic sensitizations: A genome-scale longitudinal study during adolescence

(2019) Hongmei Zhang et al.   ALLERGY

Birch pollen allergen-specific immunotherapy with glutaraldehyde-modified allergoid induces IL-10 secretion and protective antibody responses

(2019) Michèle Myriam Rauber et al.   ALLERGY

Variability of allergens in commercial fish extracts for skin prick testing

(2019) Thimo Ruethers et al.   ALLERGY

Soluble Fcɛ RI : a biomarker for IgE‐mediated diseases

(2019) Sherezade Moñino‐Romero et al.   ALLERGY

Towards clinically applicable biomarkers for asthma – An EAACI position paper

(2019) Zuzana Diamant et al.   ALLERGY

Allergen databases – a critical evaluation

(2019) C. Radauer et al.   ALLERGY

Modulation of CRT h2 expression on allergen‐specific T cells following peptide immunotherapy

(2019) Christopher D. Rudulier et al.   ALLERGY

Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care

(2019) Heimo Breiteneder et al.   ALLERGY

Interaction of Alt a 1 with SLC 22A17 in the airway mucosa

(2019) María Garrido‐Arandia et al.   ALLERGY

Only aG al bound to lipids, but not to proteins, is transported across enterocytes as an IgE reactive molecule that can induce effector cell activation

(2019) Patricia Román‐Carrasco et al.   ALLERGY

Identification and mutational analysis of continuous, immunodominant epitopes of the major oyster allergen Crag 1

(2019) Lei Fang et al.   CLINICAL IMMUNOLOGY

Resistance of parvalbumin to gastrointestinal digestion is required for profound and long‐lasting prophylactic oral tolerance

(2019) Raphaela Freidl et al.   ALLERGY

Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity

(2019) Wai Tuck Soh et al.   ALLERGY

Class-Switch Recombination Occurs Infrequently in Germinal Centers

(2019) Jonathan A. Roco et al.   IMMUNITY

Novel Nanofluidic IgE Assay versus a Reference Method: A Real-World Comparison

(2019) Samuel Roethlisberger et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Peptides from allergenic lipocalins bind to Formyl-Peptide-Receptor 3 in human dendritic cells to mediate Th2 immunity.

(2019) Dominik Klaver et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

FOXP3 expression, vitamins D and C in the prediction of tolerance acquisition in infants with cow’s milk allergy

(2019) I Sardecka et al.   JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY

Possible utility of basophil activation test in dual honeybee and vespid sensitization

(2019) Danijela Bokanovic et al.   Journal of Allergy and Clinical Immunology-In Practice

Comparison of two multiplex arrays in the diagnostics of allergy

(2019) Jana Bojcukova et al.   Clinical and Translational Allergy

Keep the cat, change the care pathway: A transformational approach to managing Fel d 1, the major cat allergen

(2019) Ebenezer Satyaraj et al.   ALLERGY

Development of a novel Ara h 2 hypoallergen with no IgE binding or anaphylactogenic activity

(2019) Angelika Tscheppe et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Fish-derived low molecular weight components modify bronchial epithelial barrier properties and release of pro-inflammatory cytokines

(2019) Tanja Kalic et al.   MOLECULAR IMMUNOLOGY

Clinical and Molecular Characterization of Walnut and Pecan Allergy (NUT CRACKER Study)

(2019) Arnon Elizur et al.   Journal of Allergy and Clinical Immunology-In Practice

Cross‐reactivities of non‐homologous allergens

(2019) Merima Bublin et al.   ALLERGY

Virus like particles displaying major HDM allergen Der p 2 for prophylactic allergen immunotherapy

(2019) Tewarit Soongrung et al.   ALLERGY

Recent developments and highlights in food allergy

(2019) Thomas Eiwegger et al.   ALLERGY

TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures

(2019) Ang A. Tu et al.   NATURE IMMUNOLOGY

Ole e 15 and its human counterpart -PPIA- chimeras reveal an heterogeneous IgE response in olive pollen allergic patients

(2019) Pablo San Segundo-Acosta et al.   Scientific Reports

Conservation Analysis of B-Cell Allergen Epitopes to Predict Clinical Cross-Reactivity Between Shellfish and Inhalant Invertebrate Allergens

(2019) Roni Nugraha et al.   Frontiers in Immunology

Laser‐facilitated epicutaneous immunotherapy with depigmented house dust mite extract alleviates allergic responses in a mouse model of allergic lung inflammation

(2019) Evgeniia Korotchenko et al.   ALLERGY

Are allergens more abundant and/or more stable than other proteins in pollens and dust?

(2019) Aurora Cabrera et al.   ALLERGY

The quest for ingested peanut protein in human serum

(2019) Anja Pahlow Mose et al.   ALLERGY

Perspectives in allergen immunotherapy: 2019 and beyond

(2019) Oliver Pfaar et al.   ALLERGY

A novel tool for clinical diagnosis of allergy operating a microfluidic immunoaffinity basophil activation test technique

(2019) Zenib Aljadi et al.   CLINICAL IMMUNOLOGY

Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens

(2019) Federico Storni et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Novel Bead-Based Epitope Assay is a sensitive and reliable tool for profiling epitope-specific antibody repertoire in food allergy

(2019) Maria Suprun et al.   Scientific Reports

Major hazelnut and peanut allergens are potent in basophil activation and cross-react at T-cell level

(2018) L. J. N. Masthoff et al.   ALLERGY

Immunoprofile of α-Gal- and B-antigen-specific responses differentiates red meat-allergic patients from healthy individuals

(2018) D. Apostolovic et al.   ALLERGY

Isolation of a high-affinity Bet v 1-specific IgG-derived ScFv from a subject vaccinated with hypoallergenic Bet v 1 fragments

(2018) E. Gadermaier et al.   ALLERGY

A novel glycocluster molecule prevents timothy-induced allergic airway inflammation in mice

(2018) M. Lehto et al.   ALLERGY

Identification of T-cell epitopes from benzylpenicillin conjugated to human serum albumin and implication in penicillin allergy

(2018) M. E. Azoury et al.   ALLERGY

Peanut lipids display potential adjuvanticity by triggering a pro-inflammatory response in human keratinocytes

(2018) C. Palladino et al.   ALLERGY

The use of omalizumab in allergen immunotherapy

(2018) J. A. Dantzer et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Characterization of Vibrio cholerae neuraminidase as an immunomodulator for novel formulation of oral allergy immunotherapy

(2018) Susanne C. Diesner et al.   CLINICAL IMMUNOLOGY

Update on Omalizumab for Urticaria: What’s New in the Literature from Mechanisms to Clinic

(2018) Désirée E. S. Larenas-Linnemann et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Modified Allergens for Immunotherapy

(2018) Pattraporn Satitsuksanoa et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Misleading Allergens in the Diagnosis of Latex Allergy: Profilin and Cross-Reactive Carbohydrate Determinants

(2018) Feridun Gürlek et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Venoms of Neotropical wasps lack cross-reactive carbohydrate determinants enabling reliable protein-based specific IgE determination

(2018) Amilcar Perez-Riverol et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Induction of bystander tolerance and immune deviation after Fel d 1 peptide immunotherapy

(2018) Daniel M. Moldaver et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hypoallergenic casein hydrolysate for peptide-based oral immunotherapy in cow's milk allergy

(2018) Hiroshi M. Ueno et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular allergy diagnostics refine characterization of children sensitized to dog dander

(2018) Ulrika Käck et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Personalized and rapid test for food-related allergy

(2018) Mikaël Frossard et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rapid and comprehensive discovery of unreported shellfish allergens using large-scale transcriptomic and proteomic resources

(2018) Roni Nugraha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A bispecific antibody strategy to target multiple type 2 cytokines in asthma

(2018) Marie Godar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Safety and efficacy of immunotherapy with the recombinant B-cell epitope–based grass pollen vaccine BM32

(2018) Verena Niederberger et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Stability of allergens

(2018) Judith Pekar et al.   MOLECULAR IMMUNOLOGY

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement

(2018) J. M. Orengo et al.   Nature Communications

The high molecular weight dipeptidyl peptidase IV Pol d 3 is a major allergen of Polistes dominula venom

(2018) Maximilian Schiener et al.   Scientific Reports

Steroid Allergy: Clinical Features and the Importance of Excipient Testing in a Diagnostic Algorithm

(2018) Philip H. Li et al.   Journal of Allergy and Clinical Immunology-In Practice

The B antigen protects against the development of red meat allergy

(2018) Jonathan R. Brestoff et al.   Journal of Allergy and Clinical Immunology-In Practice

Ara h 2 basophil activation test does not predict clinical reactivity to peanut

(2018) Alexandra Chapuis et al.   Journal of Allergy and Clinical Immunology-In Practice

A new luminex-based peptide assay to identify reactivity to baked, fermented and whole milk

(2018) Cansin Sackesen et al.   ALLERGY

Do mucosal biomarkers reveal the immunological state associated with food allergy?

(2018) Eliete Neves Silva Guerra et al.   ALLERGY

Prevention of allergy by virus-like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model

(2018) Bernhard Kratzer et al.   ALLERGY

Egg allergen specific IgE diversity predicts resolution of egg allergy in the population cohort HealthNuts

(2018) Thanh D Dang et al.   ALLERGY

Mapping of conformational IgE epitopes of food allergens

(2018) Heimo Breiteneder   ALLERGY

Underestimation of house dust mite–specific IgE with extract-based ImmunoCAPs compared with molecular ImmunoCAPs

(2018) Huey-Jy Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergen content in German cockroach extracts and sensitization profiles to a new expanded set of cockroach allergens determine in vitro extract potency for IgE reactivity

(2018) Jill Glesner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Glutathione S-transferase (GST) of American Cockroach, Periplaneta americana: Classes, Isoforms, and Allergenicity

(2018) Nitat Sookrung et al.   Scientific Reports

Jug r 6 is the allergenic vicilin present in walnut responsible for IgE cross-reactivities to other tree nuts and seeds

(2018) Pawel Dubiela et al.   Scientific Reports

Cross-reactive aeroallergens: which need to cross our mind in food allergy diagnosis?

(2018) Margaretha A. Faber et al.   Journal of Allergy and Clinical Immunology-In Practice

Exploring the diagnosis and profile of cannabis allergy

(2018) Ine Ilona Decuyper et al.   Journal of Allergy and Clinical Immunology-In Practice

Distinct Lipid Transfer Proteins display different IgE‐binding activities that are affected by fatty acid binding

(2018) Roberta Aina et al.   ALLERGY

Chemically modified peanut extract shows increased safety while maintaining immunogenicity

(2018) Hanneke P. M. van der Kleij et al.   ALLERGY

Recent developments and highlights in biomarkers in allergic diseases and asthma

(2018) Ibon Eguiluz-Gracia et al.   ALLERGY

Recent developments and highlights in allergen immunotherapy

(2018) Oliver Pfaar et al.   ALLERGY

Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper

(2018) Franziska Roth-Walter et al.   ALLERGY

Basophil Activation Test: Old and New Applications in Allergy

(2018) Oliver Hemmings et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Engineering of structural variants of the major peanut allergens Ara h 2 and Ara h 6 for allergen-specific immunotherapy

(2018) Merima Bublin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peanut allergen–specific antibodies go public

(2018) Hannah J. Gould et al.   SCIENCE

High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes

(2018) Derek Croote et al.   SCIENCE

Patients Allergic to Fish Tolerate Ray Based on the Low Allergenicity of Its Parvalbumin

(2018) Tanja Kalic et al.   Journal of Allergy and Clinical Immunology-In Practice

Allergen Extracts for In Vivo Diagnosis and Treatment of Allergy: Is There a Future?

(2018) Rudolf Valenta et al.   Journal of Allergy and Clinical Immunology-In Practice

Recombinant Allergens in Structural Biology, Diagnosis, and Immunotherapy

(2017) Angelika Tscheppe et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Early life innate immune signatures of persistent food allergy

(2017) Melanie R. Neeland et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Enhanced Pru p 3 IgE-binding activity by selective free fatty acid-interaction

(2017) Pawel Dubiela et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A phenotypically and functionally distinct human T H 2 cell subpopulation is associated with allergic disorders

(2017) Erik Wambre et al.   Science Translational Medicine

Major findings and recent advances in virus–like particle (VLP)-based vaccines

(2017) Mona O. Mohsen et al.   SEMINARS IN IMMUNOLOGY

Proteomic profiling of the weed feverfew, a neglected pollen allergen source

(2017) Isabel Pablos et al.   Scientific Reports

Determination of Crucial Immunogenic Epitopes in Major Peanut Allergy Protein, Ara h2, via Novel Nanoallergen Platform

(2017) Peter E. Deak et al.   Scientific Reports

The conformational IgE epitope profile of soya bean allergen Gly m 4

(2016) F. Husslik et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Cloning and Expression of Human Monoclonal Antibodies: Implications for Allergen Immunotherapy

(2016) Louisa K. James   CURRENT ALLERGY AND ASTHMA REPORTS

Allergy-Protective Arabinogalactan Modulates Human Dendritic Cells via C-Type Lectins and Inhibition of NF-κB

(2016) Marcus Peters et al.   JOURNAL OF IMMUNOLOGY

High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum

(2015) Anders Christiansen et al.   Scientific Reports

Component-resolved diagnosis of vespid venom-allergic individuals: phospholipases and antigen 5s are necessary to identify Vespula or Polistes sensitization

(2012) R. I. Monsalve et al.   ALLERGY

Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis

(2008) Gabrielle Pauli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY