The Role of Eosinophils in Immunotherapy

Effectiveness and safety of dupilumab for the treatment of atopic dermatitis in a real-life French multicenter adult cohort

(2019) Sarah Faiz et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Summary of the updated international consensus diagnostic criteria for eosinophilic esophagitis: AGREE conference ,

(2018) Jonathan M. Spergel et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis

(2018) Maureen Egan et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Eosinophilic esophagitis and symptoms possibly related to eosinophilic esophagitis in oral immunotherapy

(2018) Daniel Petroni et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

A Randomized, Double-Blind, Placebo-Controlled, Ascending Dose Phase 1 Study of AK002, a Novel Siglec-8 Selective Monoclonal Antibody, in Healthy Subjects

(2018) Henrik S. Rasmussen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficacy and safety of lebrikizumab (an anti-IL-13 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical corticosteroids: A randomized, placebo-controlled phase II trial (TREBLE)

(2018) Eric L. Simpson et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma

(2018) Klaus F. Rabe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Eosinophils from Physiology to Disease: A Comprehensive Review

(2018) Giuseppe A. Ramirez et al.   Biomed Research International

Benralizumab: From the Basic Mechanism of Action to the Potential Use in the Biological Therapy of Severe Eosinophilic Asthma

(2018) Corrado Pelaia et al.   Biomed Research International

Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age

(2018) W. Gerald Teague et al.   Journal of Allergy and Clinical Immunology-In Practice

Assessment of the long-term safety of mepolizumab and durability of clinical response in patients with severe eosinophilic asthma

(2018) Sumita Khatri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Oral immunotherapy–induced gastrointestinal symptoms and peripheral blood eosinophil responses

(2017) Michael R. Goldberg et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Reduced need for surgery in severe nasal polyposis with mepolizumab: Randomized trial

(2017) Claus Bachert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial

(2017) Andrew Blauvelt et al.   LANCET

Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis

(2017) Michael E. Wechsler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tezepelumab in Adults with Uncontrolled Asthma

(2017) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Eosinophilic Esophagitis: A Primary Disease of the Esophageal Mucosa

(2017) J. Pablo Abonia et al.   Journal of Allergy and Clinical Immunology-In Practice

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma

(2016) Jonathan Corren et al.   CHEST

Food allergen immunotherapy: Current status and prospects for the future

(2016) Robert A. Wood   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

(2016) Sally Wenzel et al.   LANCET

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

(2016) Eric L. Simpson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Elevated blood eosinophils in early infancy are predictive of atopic dermatitis in children with risk for atopy

(2016) Siri Rossberg et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Eosinophilia in Hematologic Disorders

(2015) Lorenzo Falchi et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Intravenous anti–IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis

(2015) Marc E. Rothenberg et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eosinophilic Esophagitis

(2015) Glenn T. Furuta et al.   NEW ENGLAND JOURNAL OF MEDICINE

Food specific oral immunotherapy: a potential treatment for food allergy

(2015) Allison J Burbank et al.   Expert Review of Gastroenterology & Hepatology

Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial

(2015) Christopher E Brightling et al.   Lancet Respiratory Medicine

Blood eosinophil count and prospective annual asthma disease burden: a UK cohort study

(2015) David B Price et al.   Lancet Respiratory Medicine

Hematologic Malignancies Identified in Patients with Hypereosinophilia and Hypereosinophilic Syndromes

(2015) Jay J. Jin et al.   Journal of Allergy and Clinical Immunology-In Practice

A Pilot Study of Omalizumab in Eosinophilic Esophagitis

(2015) Denise Loizou et al.   PLoS One

Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome

(2014) Julie M. Caldwell et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses

(2014) Gail M. Gauvreau et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma

(2014) Hector G. Ortega et al.   NEW ENGLAND JOURNAL OF MEDICINE

Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study

(2014) Mario Castro et al.   Lancet Respiratory Medicine

High eosinophil count: A potential biomarker for assessing successful omalizumab treatment effects

(2013) William Busse et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Long-term follow-up of FIP1L1-PDGFRA-mutated patients with eosinophilia: survival and clinical outcome

(2012) A Pardanani et al.   LEUKEMIA

Allergen immunotherapy

(2011) David J. Fitzhugh et al.   Current Opinion in Allergy and Clinical Immunology

An Antibody Against IL-5 Reduces Numbers of Esophageal Intraepithelial Eosinophils in Children With Eosinophilic Esophagitis

(2011) Amal H. Assa'ad et al.   GASTROENTEROLOGY

Reslizumab in children and adolescents with eosinophilic esophagitis: Results of a double-blind, randomized, placebo-controlled trial

(2011) Jonathan M. Spergel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical and Immunologic Effects of Sublingual Immunotherapy on Patients with Allergic Rhinitis to House-Dust Mites: 1-Year follow-up Results

(2010) Seung-Tae Kim et al.   American Journal of Rhinology & Allergy

MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

(2010) Roland Kolbeck et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Evaluation of serum s-IgE/total IgE ratio in predicting clinical response to allergen-specific immunotherapy

(2009) Gabriele Di Lorenzo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Safety of a peanut oral immunotherapy protocol in children with peanut allergy

(2009) Alison M. Hofmann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effect of omalizumab on peripheral blood eosinophilia in allergic asthma

(2009) M. Massanari et al.   RESPIRATORY MEDICINE

Treatment of Patients with the Hypereosinophilic Syndrome with Mepolizumab

(2008) Marc E. Rothenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE