The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy
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Title
The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy
Authors
Keywords
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Journal
Frontiers in Cell and Developmental Biology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-06-10
DOI
10.3389/fcell.2020.00413
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Note: Only part of the references are listed.- p53/BNIP3-dependent mitophagy limits glycolytic shift in radioresistant cancer
- (2019) Hyo Won Chang et al. ONCOGENE
- Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to B5G1, a new betulinic acid analog
- (2019) Nan Yao et al. Cell Death & Disease
- Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing
- (2019) Yifan Zhang et al. NATURE IMMUNOLOGY
- The emerging, multifaceted role of mitophagy in cancer and cancer therapeutics
- (2019) Debasna P. Panigrahi et al. SEMINARS IN CANCER BIOLOGY
- Oncogenic Kras induces Nix-mediated mitophagy to promote pancreatic cancer
- (2019) Timothy J Humpton et al. Cancer Discovery
- Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma
- (2019) Jinkyu Jung et al. CANCER RESEARCH
- Mitochondrial Dynamics and Its Involvement in Disease
- (2019) David C. Chan Annual Review of Pathology-Mechanisms of Disease
- Mitochondria-acting nanomicelles for destruction of cancer cells via excessive mitophagy/autophagy-driven lethal energy depletion and phototherapy
- (2019) Ya-Xuan Zhu et al. BIOMATERIALS
- AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells
- (2018) Nina Meyer et al. Autophagy
- PUMA dependent mitophagy by Abrus agglutinin contributes to apoptosis through ceramide generation
- (2018) Prashanta Kumar Panda et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Silencing of PINK1 represses cell growth, migration and induces apoptosis of lung cancer cells
- (2018) Lihua Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol
- (2018) Shiori Sekine et al. BMC BIOLOGY
- Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination
- (2018) Yong Sun Lee et al. CANCER LETTERS
- Correction: The side effects of platinum-based chemotherapy drugs: a review for chemists
- (2018) Rabbab Oun et al. DALTON TRANSACTIONS
- Mitochondrial dynamics: overview of molecular mechanisms
- (2018) Lisa Tilokani et al. Essays in Biochemistry
- Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways
- (2018) Chen Shi et al. Redox Biology
- FUNDC1-mediated mitophagy suppresses hepatocarcinogenesis by inhibition of inflammasome activation
- (2018) Wenhui Li et al. HEPATOLOGY
- Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation
- (2018) Kathleen A. Boyle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hydrogen peroxide-induced mitophagy contributes to laryngeal cancer cells survival via the upregulation of FUNDC1
- (2018) L. Hui et al. Clinical & Translational Oncology
- Structure of PINK1 in complex with its substrate ubiquitin
- (2017) Alexander F. Schubert et al. NATURE
- Elements of cancer immunity and the cancer–immune set point
- (2017) Daniel S. Chen et al. NATURE
- MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion
- (2017) Yu-Lu Cao et al. NATURE
- Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells
- (2017) Farhan Basit et al. Cell Death & Disease
- Targeted apoptosis in ovarian cancer cells through mitochondrial dysfunction in response to Sambucus nigra agglutinin
- (2017) Shreya Roy Chowdhury et al. Cell Death & Disease
- microRNA-488 inhibits chemoresistance of ovarian cancer cells by targeting Six1 and mitochondrial function
- (2017) Zhuo Yang et al. Oncotarget
- Parkin-Independent Mitophagy Controls Chemotherapeutic Response in Cancer Cells
- (2017) Elodie Villa et al. Cell Reports
- Galectin-1 promotes tumor progression via NF-κB signaling pathway in epithelial ovarian cancer
- (2017) Le Chen et al. Journal of Cancer
- High expression of FUNDC1 predicts poor prognostic outcomes and is a promising target to improve chemoradiotherapy effects in patients with cervical cancer
- (2017) Hailing Hou et al. Cancer Medicine
- Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function
- (2016) Lena Pernas et al. Annual Review of Physiology
- Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML
- (2016) Mohammed Dany et al. BLOOD
- Mitochondria and Cancer
- (2016) Sejal Vyas et al. CELL
- Dihydroergotamine Tartrate Induces Lung Cancer Cell Death through Apoptosis and Mitophagy
- (2016) Seung-Hee Chang et al. CHEMOTHERAPY
- Regulators of mitochondrial dynamics in cancer
- (2016) Daniela Senft et al. CURRENT OPINION IN CELL BIOLOGY
- Metabolic regulation of mitochondrial dynamics
- (2016) Prashant Mishra et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial dynamics, mitophagy and cardiovascular disease
- (2016) César Vásquez-Trincado et al. JOURNAL OF PHYSIOLOGY-LONDON
- Parkin and mitophagy in cancer
- (2016) J P Bernardini et al. ONCOGENE
- Mitochondrial Dynamics and Metabolic Regulation
- (2016) Timothy Wai et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Galectin-1-Induced Autophagy Facilitates Cisplatin Resistance of Hepatocellular Carcinoma
- (2016) Yu-Chi Su et al. PLoS One
- BCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32
- (2015) Kinya Otsu et al. Autophagy
- A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission
- (2015) Jing Zhou et al. Autophagy
- Expression of BNIP3 and its correlations to hypoxia-induced autophagy and clinicopathological features in salivary adenoid cystic carcinoma
- (2015) Zhanwei Chen et al. Cancer Biomarkers
- Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
- (2015) A. H. Chourasia et al. EMBO REPORTS
- Mitochondria and the hallmarks of cancer
- (2015) Evangelos Giampazolias et al. FEBS Journal
- Expression profile of parkin isoforms in human gliomas
- (2015) GRAZIA MAUGERI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Hypoxia-induced autophagy contributes to the invasion of salivary adenoid cystic carcinoma through the HIF-1α/BNIP3 signaling pathway
- (2015) HAIWEI WU et al. Molecular Medicine Reports
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- Mitochondrial control by DRP1 in brain tumor initiating cells
- (2015) Qi Xie et al. NATURE NEUROSCIENCE
- Expression pattern of parkin isoforms in lung adenocarcinomas
- (2015) Agata Grazia D’Amico et al. TUMOR BIOLOGY
- Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
- (2015) Tomokazu Murakawa et al. Nature Communications
- Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells
- (2015) Hui-Mei Wu et al. Scientific Reports
- Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation
- (2015) Xiyu Zhang et al. Scientific Reports
- Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites
- (2015) Wei-ke Ji et al. eLife
- Mitochondrial dynamics and mitochondrial quality control
- (2015) Hong-Min Ni et al. Redox Biology
- AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
- (2014) F Strappazzon et al. CELL DEATH AND DIFFERENTIATION
- BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke
- (2014) Ruo-Yang Shi et al. CNS Neuroscience & Therapeutics
- A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy
- (2014) Guo Chen et al. MOLECULAR CELL
- A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1
- (2014) Jingnan Wang et al. Molecular Oncology
- The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
- (2014) Baris Bingol et al. NATURE
- Involvement of Drp1 in hypoxia-induced migration of human glioblastoma U251 cells
- (2014) YU-YING WAN et al. ONCOLOGY REPORTS
- BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton
- (2014) H Maes et al. Cell Death & Disease
- A dual role for autophagy in a murine model of lung cancer
- (2014) Shuan Rao et al. Nature Communications
- Regulation and function of mitophagy in development and cancer
- (2013) Haiqi Lu et al. Autophagy
- Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation
- (2013) Xiaodong Sun et al. CELL CYCLE
- Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
- (2013) J. Y. Guo et al. GENES & DEVELOPMENT
- Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission
- (2013) Oliver C. Losón et al. MOLECULAR BIOLOGY OF THE CELL
- Replication stress links structural and numerical cancer chromosomal instability
- (2013) Rebecca A. Burrell et al. NATURE
- p53 status determines the role of autophagy in pancreatic tumour development
- (2013) Mathias T. Rosenfeldt et al. NATURE
- Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway
- (2013) Wei-jia Wang et al. Nature Chemical Biology
- An Improved Quantitative Approach for the Assessment of Mitochondrial Fragmentation in Chemoresistant Ovarian Cancer Cells
- (2013) Lee Farrand et al. PLoS One
- Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy
- (2013) Hagai Abeliovich et al. Nature Communications
- Ceramide stress in survival versus lethal autophagy paradox
- (2012) Wenhui Jiang et al. Autophagy
- The pathways of mitophagy for quality control and clearance of mitochondria
- (2012) G Ashrafi et al. CELL DEATH AND DIFFERENTIATION
- Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer
- (2012) Jalees Rehman et al. FASEB JOURNAL
- Modulation of Serines 17 and 24 in the LC3-interacting Region of Bnip3 Determines Pro-survival MitophagyversusApoptosis
- (2012) Yanyan Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy
- (2012) Noriko Kondo-Okamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
- (2012) Lei Liu et al. NATURE CELL BIOLOGY
- Mitochondrial dynamics regulates migration and invasion of breast cancer cells
- (2012) J Zhao et al. ONCOGENE
- New aspects of the Warburg effect in cancer cell biology
- (2012) Steven J. Bensinger et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
- (2012) C. Kondapalli et al. Open Biology
- Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health
- (2011) David C. Chan Annual Review of Genetics
- Mitochondria Autophagy in Yeast
- (2011) Tomotake Kanki et al. ANTIOXIDANTS & REDOX SIGNALING
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- Bnip3 as a Dual Regulator of Mitochondrial Turnover and Cell Death in the Myocardium
- (2011) Åsa B. Gustafsson PEDIATRIC CARDIOLOGY
- Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
- (2011) C. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1
- (2010) Chuang-Rung Chang et al. Annals of the New York Academy of Sciences
- Targeting mitochondria for cancer therapy
- (2010) David M. Hockenbery ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Parkin Enhances the Expression of Cyclin-dependent Kinase 6 and Negatively Regulates the Proliferation of Breast Cancer Cells
- (2010) Shiam-Peng Tay et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice
- (2010) G. Poulogiannis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Turnover of organelles by autophagy in yeast
- (2009) Jean-Claude Farré et al. CURRENT OPINION IN CELL BIOLOGY
- Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy
- (2009) Tomotake Kanki et al. DEVELOPMENTAL CELL
- Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
- (2009) Koji Okamoto et al. DEVELOPMENTAL CELL
- Nix is a selective autophagy receptor for mitochondrial clearance
- (2009) Ivana Novak et al. EMBO REPORTS
- Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
- (2009) Selvaraju Veeriah et al. NATURE GENETICS
- Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
- (2008) Ann Cassidy-Stone et al. DEVELOPMENTAL CELL
- Essential role for Nix in autophagic maturation of erythroid cells
- (2008) Hector Sandoval et al. NATURE
- Parkin as a tumor suppressor gene for hepatocellular carcinoma
- (2008) M Fujiwara et al. ONCOGENE
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