Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cep70 contributes to angiogenesis by modulating microtubule rearrangement and stimulating cell polarization and migration

(2012) Xingjuan Shi et al.   CELL CYCLE

The C-terminus of PARK2 is required for its self-interaction, solubility and role in the spindle assembly checkpoint

(2011) Yvan Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mdp3 is a novel microtubule-binding protein that regulates microtubule assembly and stability

(2011) Xiaoou Sun et al.   CELL CYCLE

Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development

(2011) Xavier Morin et al.   DEVELOPMENTAL CELL

Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project

(2011) Christine A Iacobuzio-Donahue   GUT

Mitotic spindle misorientation in cancer - out of alignment and into the fire

(2011) J. C. Pease et al.   JOURNAL OF CELL SCIENCE

Parkin Mediates Apparent E2-Independent Monoubiquitination In Vitro and Contains an Intrinsic Activity That Catalyzes Polyubiquitination

(2011) Katherine C. M. Chew et al.   PLoS One

Common fragile sites: mechanisms of instability revisited

(2011) Michelle Debatisse et al.   TRENDS IN GENETICS

Ectopic expression of the microtubule-dependent motor protein Eg5 promotes pancreatic tumourigenesis

(2010) Min Liu et al.   JOURNAL OF PATHOLOGY

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

(2010) Peter J. Campbell et al.   NATURE

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice

(2010) G. Poulogiannis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair

(2009) Oliver Rothfuss et al.   HUMAN MOLECULAR GENETICS

Parkin regulates paclitaxel sensitivity in breast cancer via a microtubule-dependent mechanism

(2009) Hongxia Wang et al.   JOURNAL OF PATHOLOGY

Cadherin Adhesion Receptors Orient the Mitotic Spindle during Symmetric Cell Division in Mammalian Epithelia

(2009) Nicole den Elzen et al.   MOLECULAR BIOLOGY OF THE CELL

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

VHL loss causes spindle misorientation and chromosome instability

(2009) Claudio R. Thoma et al.   NATURE CELL BIOLOGY

Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies

(2009) Selvaraju Veeriah et al.   NATURE GENETICS

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Parkin Regulates Eg5 Expression by Hsp70 Ubiquitination-dependent Inactivation of c-Jun NH2-terminal Kinase

(2008) Min Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin mediates the degradation-independent ubiquitination of Hsp70

(2008) Darren J. Moore et al.   JOURNAL OF NEUROCHEMISTRY

Parkin as a tumor suppressor gene for hepatocellular carcinoma

(2008) M Fujiwara et al.   ONCOGENE

Pancreatic Carcinogenesis

(2008) Jan-Bart M. Koorstra et al.   PANCREATOLOGY