AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells
Authors
Keywords
-
Journal
Autophagy
Volume -, Issue -, Pages 1-17
Publisher
Informa UK Limited
Online
2018-07-21
DOI
10.1080/15548627.2018.1476812
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A novel role of the mitochondrial permeability transition pore in (−)-gossypol-induced mitochondrial dysfunction
- (2018) Verena Warnsmann et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
- (2017) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy irrespective of expression levels and the subcellular localization of Bcl-xL and Bcl-2 in MCF7 cells
- (2016) P. Antonietti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Autophagy and the invisible line between life and death
- (2016) Chrisna Swart et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- BCL2 Inhibitors as Anticancer Drugs: A Plethora of Misleading BH3 Mimetics
- (2016) R. S. Soderquist et al. MOLECULAR CANCER THERAPEUTICS
- Flow Cytometry-Based Assessment of Mitophagy Using MitoTracker
- (2016) Bin Xiao et al. Frontiers in Cellular Neuroscience
- Cyclophilin D Is Involved in the Regulation of Autophagy and Affects the Lifespan of P. anserina in Response to Mitochondrial Oxidative Stress
- (2016) Piet Kramer et al. Frontiers in Genetics
- Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways
- (2015) Yuko Hirota et al. Autophagy
- Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX
- (2015) Paul A. Ney BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit
- (2015) Ksenya Shchors et al. CANCER CELL
- Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma
- (2015) D.-C. Lin et al. CANCER RESEARCH
- Lysosomal proteins in cell death and autophagy
- (2015) Michaela Mrschtik et al. FEBS Journal
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy
- (2015) S Fulda et al. ONCOGENE
- Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
- (2015) Min-Young Kwon et al. Oncotarget
- A critical role of superoxide anion in selenite-induced mitophagic cell death
- (2014) Eun Hee Kim et al. Autophagy
- Identification of autophagy as a longevity-assurance mechanism in the aging modelPodospora anserina
- (2014) Laura Knuppertz et al. Autophagy
- A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis
- (2014) Vanessa Ginet et al. Autophagy
- Autosis and autophagic cell death: the dark side of autophagy
- (2014) Y Liu et al. CELL DEATH AND DIFFERENTIATION
- Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
- (2014) L Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Receptor-mediated mitophagy in yeast and mammalian systems
- (2014) Lei Liu et al. CELL RESEARCH
- Self-consumption: the interplay of autophagy and apoptosis
- (2014) Guillermo Mariño et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- BNIP3 Regulates AT101 [(-)-Gossypol] Induced Death in Malignant Peripheral Nerve Sheath Tumor Cells
- (2014) Niroop Kaza et al. PLoS One
- Autosis: a new addition to the cell death tower of babel
- (2014) C Muñoz-Pinedo et al. Cell Death & Disease
- Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes
- (2014) Shinya Honda et al. Nature Communications
- Application and interpretation of current autophagy inhibitors and activators
- (2013) Ya-ping Yang et al. ACTA PHARMACOLOGICA SINICA
- Loss of iron triggers PINK1/Parkin-independent mitophagy
- (2013) George F G Allen et al. EMBO REPORTS
- RIP3: a molecular switch for necrosis and inflammation
- (2013) K. Moriwaki et al. GENES & DEVELOPMENT
- Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway
- (2013) Wei-jia Wang et al. Nature Chemical Biology
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Mitochondria-targeted heme oxygenase-1 induces oxidative stress and mitochondrial dysfunction in macrophages, kidney fibroblasts and in chronic alcohol hepatotoxicity
- (2013) Seema Bansal et al. Redox Biology
- Therapeutic Exploitation of Apoptosis and Autophagy for Glioblastoma
- (2012) Donat Kogel et al. Anti-Cancer Agents in Medicinal Chemistry
- Parkin Pathway Activation Mitigates Glioma Cell Proliferation and Predicts Patient Survival
- (2012) C. W. S. Yeo et al. CANCER RESEARCH
- Calpains, mitochondria, and apoptosis
- (2012) M. A. Smith et al. CARDIOVASCULAR RESEARCH
- The pathways of mitophagy for quality control and clearance of mitochondria
- (2012) G Ashrafi et al. CELL DEATH AND DIFFERENTIATION
- Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis
- (2012) Megan M. Young et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
- (2012) R David Sentelle et al. Nature Chemical Biology
- Therapeutic Potential of Heme Oxygenase-1/Carbon Monoxide in Lung Disease
- (2012) Myrna Constantin et al. International Journal of Hypertension
- Autophagy receptors in developmental clearance of mitochondria
- (2011) Ivana Novak et al. Autophagy
- A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery
- (2011) Hiroyuki Katayama et al. CHEMISTRY & BIOLOGY
- Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice
- (2011) Evie H. Carchman et al. HEPATOLOGY
- Methods in Mammalian Autophagy Research
- (2010) Noboru Mizushima et al. CELL
- Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
- (2010) Laura Bonapace et al. JOURNAL OF CLINICAL INVESTIGATION
- The Pan-Bcl-2 Inhibitor (-)-Gossypol Triggers Autophagic Cell Death in Malignant Glioma
- (2010) V. Voss et al. MOLECULAR CANCER RESEARCH
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- Role of BNIP3 and NIX in cell death, autophagy and mitophagy
- (2009) J Zhang et al. CELL DEATH AND DIFFERENTIATION
- Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
- (2009) María Salazar et al. JOURNAL OF CLINICAL INVESTIGATION
- HO-1-mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues
- (2009) Hillel Zukor et al. JOURNAL OF NEUROCHEMISTRY
- RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
- (2009) D.-W. Zhang et al. SCIENCE
- The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death
- (2008) Francesco Cecconi et al. DEVELOPMENTAL CELL
- Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis
- (2008) Holger Hetschko et al. FEBS Journal
- Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
- (2008) Huafeng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry
- (2008) Judit Villén et al. Nature Protocols
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More