The Roles of Embryonic Transcription Factor BRACHYURY in Tumorigenesis and Progression
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Roles of Embryonic Transcription Factor BRACHYURY in Tumorigenesis and Progression
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-06-30
DOI
10.3389/fonc.2020.00961
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The T‐box transcription factor brachyury behaves as a tumor suppressor in gliomas
- (2020) Filipe Pinto et al. JOURNAL OF PATHOLOGY
- Small-molecule targeting of brachyury transcription factor addiction in chordoma
- (2019) Tanaz Sharifnia et al. NATURE MEDICINE
- The basics of epithelial–mesenchymal transition (EMT): A study from a structure, dynamics, and functional perspective
- (2019) Vishal Das et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Transactivation of SOX5 by Brachyury promotes breast cancer bone metastasis
- (2019) Ming Chen et al. CARCINOGENESIS
- Long non-coding RNA CRYBG3 blocks cytokinesis by directly binding G-actin
- (2018) Hailong Pei et al. CANCER RESEARCH
- Quick efficacy seeking trial (QuEST1): a novel combination immunotherapy study designed for rapid clinical signal assessment metastatic castration-resistant prostate cancer
- (2018) Jason M. Redman et al. Journal for ImmunoTherapy of Cancer
- Prognostic significance of expression of epithelial‑mesenchymal transition driver brachyury in breast cancer and its association with subtype and characteristics
- (2017) Kwan Lee et al. Oncology Letters
- Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer
- (2017) Sagar R. Shah et al. Cell Reports
- Prognostic Significance of Expression of the Epithelial-Mesenchymal Transition-Related Factor Brachyury in Intrathoracic Lymphatic Spread of Non-Small Cell Lung Cancer
- (2016) Shinichiro Shimamatsu et al. ANNALS OF SURGICAL ONCOLOGY
- Brachyury promotes tamoxifen resistance in breast cancer by targeting SIRT1
- (2016) Kaichun Li et al. BIOMEDICINE & PHARMACOTHERAPY
- Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer
- (2016) Duane H Hamilton et al. ENDOCRINE-RELATED CANCER
- SMC1 promotes epithelial-mesenchymal transition in triple-negative breast cancer through upregulating Brachyury
- (2016) KAICHUN LI et al. ONCOLOGY REPORTS
- T-box transcription factor brachyury promotes tumor cell invasion and metastasis in non-small cell lung cancer via upregulation of matrix metalloproteinase 12
- (2016) ZONGMIAO WAN et al. ONCOLOGY REPORTS
- Putative oncogeneBrachyury(T) is essential to specify cell fate but dispensable for notochord progenitor proliferation and EMT
- (2016) Jianjian Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of brachyury by fibroblast growth factor receptor 1 in lung cancer
- (2016) Yunping Hu et al. Oncotarget
- Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer
- (2016) Filipe Pinto et al. Oncotarget
- Distinctive Roles of Canonical and Noncanonical Wnt Signaling in Human Embryonic Cardiomyocyte Development
- (2016) Silvia Mazzotta et al. Stem Cell Reports
- Nuclear Brachyury Expression Is Consistent in Chordoma, Common in Germ Cell Tumors and Small Cell Carcinomas, and Rare in Other Carcinomas and Sarcomas
- (2015) Markku Miettinen et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- The potential role of Brachyury in inducing epithelial-to-mesenchymal transition (EMT) and HIF-1α expression in breast cancer cells
- (2015) Chao Shao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Impact of Brachyury on epithelial-mesenchymal transitions and chemosensitivity in non-small cell lung cancer
- (2015) KE XU et al. Molecular Medicine Reports
- T-box transcription factor Brachyury in lung cancer cells inhibits macrophage infiltration by suppressing CCL2 and CCL4 chemokines
- (2015) Su Chen et al. TUMOR BIOLOGY
- Expression levels of SOX2, KLF4 and brachyury transcription factors are associated with metastasis and poor prognosis in oral squamous cell carcinoma
- (2015) RUMI YOSHIHAMA et al. Oncology Letters
- Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody
- (2015) Duane H. Hamilton et al. Oncotarget
- Phase I Trial of a Yeast-Based Therapeutic Cancer Vaccine (GI-6301) Targeting the Transcription Factor Brachyury
- (2015) C. R. Heery et al. Cancer Immunology Research
- How was the notochord born?
- (2015) Nori Satoh et al. EVOLUTION & DEVELOPMENT
- Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine
- (2015) Duane H. Hamilton et al. Oncotarget
- Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathway
- (2015) Jana Jezkova et al. Oncotarget
- The FGFR/MEK/ERK/brachyury pathway is critical for chordoma cell growth and survival
- (2014) Yunping Hu et al. CARCINOGENESIS
- T-box Transcription Factor Brachyury Is Associated with Prostate Cancer Progression and Aggressiveness
- (2014) F. Pinto et al. CLINICAL CANCER RESEARCH
- Characterization of T gene sequence variants and germline duplications in familial and sporadic chordoma
- (2014) Michael J. Kelley et al. HUMAN GENETICS
- Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
- (2014) Rui Du et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Brachyury: A New Player in Promoting Breast Cancer Aggressiveness
- (2014) M. M. Pires et al. JNCI-Journal of the National Cancer Institute
- Overexpression of the EMT Driver Brachyury in Breast Carcinomas: Association With Poor Prognosis
- (2014) Claudia Palena et al. JNCI-Journal of the National Cancer Institute
- Brachyury—a biomarker for progression and prognosis?
- (2014) Clemens Thoma Nature Reviews Urology
- Androgen-Targeted Therapy-Induced Epithelial Mesenchymal Plasticity and Neuroendocrine Transdifferentiation in Prostate Cancer: An Opportunity for Intervention
- (2014) Mannan Nouri et al. Frontiers in Oncology
- Expression of Brachyury Gene Is a Significant Prognostic Factor for Primary Lung Carcinoma
- (2013) Akira Haro et al. ANNALS OF SURGICAL ONCOLOGY
- An Autocrine Loop between TGF- 1 and the Transcription Factor Brachyury Controls the Transition of Human Carcinoma Cells into a Mesenchymal Phenotype
- (2013) C. Larocca et al. MOLECULAR CANCER THERAPEUTICS
- Histological Study of Chordoma Origin From Fetal Notochordal Cell Rests
- (2013) Jun Shen et al. SPINE
- The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies
- (2013) B Huang et al. Cell Death & Disease
- Functional Brachyury Binding Sites Establish a Temporal Read-out of Gene Expression in the Ciona Notochord
- (2013) Lavanya Katikala et al. PLOS BIOLOGY
- The T-box transcription factor Brachyury regulates epithelial–mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells
- (2012) Miyuki Shimoda et al. BMC CANCER
- Brachyury, a Driver of the Epithelial-Mesenchymal Transition, Is Overexpressed in Human Lung Tumors: An Opportunity for Novel Interventions against Lung Cancer
- (2012) M. Roselli et al. CLINICAL CANCER RESEARCH
- T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma
- (2012) IKUMI IMAJYO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- An integrated functional genomics approach identifies the regulatory network directed by brachyury (T ) in chordoma
- (2012) Andrew C Nelson et al. JOURNAL OF PATHOLOGY
- Chordoma: current concepts, management, and future directions
- (2012) Brian P Walcott et al. LANCET ONCOLOGY
- A common single-nucleotide variant in T is strongly associated with chordoma
- (2012) Nischalan Pillay et al. NATURE GENETICS
- Genome-Wide Analysis of Androgen Receptor Targets Reveals COUP-TF1 as a Novel Player in Human Prostate Cancer
- (2012) Ruth Perets et al. PLoS One
- IL-8 Signaling Plays a Critical Role in the Epithelial-Mesenchymal Transition of Human Carcinoma Cells
- (2011) R. I. Fernando et al. CANCER RESEARCH
- Brachyury expression predicts poor prognosis at early stages of colorectal cancer
- (2011) Nerbil Kilic et al. EUROPEAN JOURNAL OF CANCER
- Strategies to target molecules that control the acquisition of a mesenchymal-like phenotype by carcinoma cells
- (2011) Claudia Palena et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells
- (2011) Debalina Sarkar et al. INTERNATIONAL JOURNAL OF CANCER
- Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target
- (2011) Wesley Hsu et al. JOURNAL OF NEUROSURGERY
- Unveiling the molecular pathogenesis of chordoma: a new paradigm for molecular targeting of rare cancers
- (2011) Angelo Paolo Dei Tos JOURNAL OF PATHOLOGY
- ΔNp63 transcriptionally regulatesbrachyury, a gene with diverse roles in limb development, tumorigenesis and metastasis
- (2010) Min Soon Cho et al. CELL CYCLE
- The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells
- (2010) Romaine I. Fernando et al. JOURNAL OF CLINICAL INVESTIGATION
- Classic chordoma coexisting with benign notochordal cell rest demonstrating different immunohistological expression patterns of brachyury and galectin-3
- (2010) Jun Shen et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study
- (2010) Nadège Presneau et al. JOURNAL OF PATHOLOGY
- Brachyury Expression in Extra-axial Skeletal and Soft Tissue Chordomas: A Marker that Distinguishes Chordoma From Mixed Tumor/Myoepithelioma/Parachordoma in Soft Tissue
- (2009) Roberto Tirabosco et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- T (brachyury) gene duplication confers major susceptibility to familial chordoma
- (2009) Xiaohong R Yang et al. NATURE GENETICS
- Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo
- (2009) Sebastian J. Arnold et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A gene regulatory network directed by zebrafish No tail accounts for its roles in mesoderm formation
- (2009) R. H. Morley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Brachyury, SOX-9 and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis
- (2008) Gerard J Oakley et al. MODERN PATHOLOGY
- Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer
- (2007) Jong Chul Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now