An integrated functional genomics approach identifies the regulatory network directed by brachyury (T ) in chordoma

Phase II Study of Imatinib in Advanced Chordoma

(2012) Silvia Stacchiotti et al.   JOURNAL OF CLINICAL ONCOLOGY

The Challenge of Choosing Appropriate End Points in Single-Arm Phase II Studies of Rare Diseases

(2012) Stefan Sleijfer et al.   JOURNAL OF CLINICAL ONCOLOGY

Genomic Targets of Brachyury (T) in Differentiating Mouse Embryonic Stem Cells

(2012) Amanda L. Evans et al.   PLoS One

Aldo–Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers

(2012) Toshiyuki Matsunaga et al.   Frontiers in Pharmacology

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Efficacy of epidermal growth factor receptor targeting in advanced chordoma: case report and literature review

(2011) Simon G Launay et al.   BMC CANCER

An Antioxidant Response Phenotype Shared between Hereditary and Sporadic Type 2 Papillary Renal Cell Carcinoma

(2011) Aikseng Ooi et al.   CANCER CELL

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

IL-8 Signaling Plays a Critical Role in the Epithelial-Mesenchymal Transition of Human Carcinoma Cells

(2011) R. I. Fernando et al.   CANCER RESEARCH

Tissue-specific regulation of the number of cell division rounds by inductive cell interaction and transcription factors during ascidian embryogenesis

(2011) Tetsuya Fujikawa et al.   DEVELOPMENTAL BIOLOGY

Incidence and survival of malignant bone sarcomas in England 1979-2007

(2011) Jeremy Whelan et al.   INTERNATIONAL JOURNAL OF CANCER

Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation

(2011) Robin M. Ricke et al.   JOURNAL OF CELL BIOLOGY

Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target

(2011) Wesley Hsu et al.   JOURNAL OF NEUROSURGERY

Unveiling the molecular pathogenesis of chordoma: a new paradigm for molecular targeting of rare cancers

(2011) Angelo Paolo Dei Tos   JOURNAL OF PATHOLOGY

A signal–noise model for significance analysis of ChIP-seq with negative control

(2010) Han Xu et al.   BIOINFORMATICS

Brachyury-downstream gene sets in a chordate, Ciona intestinalis: integrating notochord specification, morphogenesis and chordate evolution

(2010) Kohji Hotta et al.   EVOLUTION & DEVELOPMENT

The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells

(2010) Romaine I. Fernando et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study

(2010) Nadège Presneau et al.   JOURNAL OF PATHOLOGY

The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target

(2010) Asem Shalaby et al.   JOURNAL OF PATHOLOGY

The Retinoblastoma Protein Modulates Tbx2 Functional Specificity

(2010) Keith W. Vance et al.   MOLECULAR BIOLOGY OF THE CELL

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours

(2010) Ping Chi et al.   NATURE

Epigenetic inactivation of T-box transcription factor 5, a novel tumor suppressor gene, is associated with colon cancer

(2010) J Yu et al.   ONCOGENE

Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences

(2010) Jeremy Goecks et al.   GENOME BIOLOGY

Brachyury Expression in Extra-axial Skeletal and Soft Tissue Chordomas: A Marker that Distinguishes Chordoma From Mixed Tumor/Myoepithelioma/Parachordoma in Soft Tissue

(2009) Roberto Tirabosco et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Whole Chromosome Instability Caused by Bub1 Insufficiency Drives Tumorigenesis through Tumor Suppressor Gene Loss of Heterozygosity

(2009) Darren J. Baker et al.   CANCER CELL

Analysis of the fibroblastic growth factor receptor-RAS/RAF/MEK/ERK-ETS2/brachyury signalling pathway in chordomas

(2009) Asem AE Shalaby et al.   MODERN PATHOLOGY

T (brachyury) gene duplication confers major susceptibility to familial chordoma

(2009) Xiaohong R Yang et al.   NATURE GENETICS

A gene regulatory network directed by zebrafish No tail accounts for its roles in mesoderm formation

(2009) R. H. Morley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Highly parallel identification of essential genes in cancer cells

(2008) B. Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Notochord, Notochordal cell and CTGF/CCN-2: ongoing activity from development through maturation

(2008) W. Mark Erwin   Journal of Cell Communication and Signaling