Androgen-Targeted Therapy-Induced Epithelial Mesenchymal Plasticity and Neuroendocrine Transdifferentiation in Prostate Cancer: An Opportunity for Intervention
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Androgen-Targeted Therapy-Induced Epithelial Mesenchymal Plasticity and Neuroendocrine Transdifferentiation in Prostate Cancer: An Opportunity for Intervention
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 4, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-12-23
DOI
10.3389/fonc.2014.00370
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine
- (2015) Duane H. Hamilton et al. Oncotarget
- Proposed Morphologic Classification of Prostate Cancer With Neuroendocrine Differentiation
- (2014) Jonathan I. Epstein et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Cancer statistics, 2014
- (2014) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Double-negative feedback loop between ZEB2 and miR-145 regulates epithelial-mesenchymal transition and stem cell properties in prostate cancer cells
- (2014) Dong Ren et al. CELL AND TISSUE RESEARCH
- T-box Transcription Factor Brachyury Is Associated with Prostate Cancer Progression and Aggressiveness
- (2014) F. Pinto et al. CLINICAL CANCER RESEARCH
- Phase I/II Trial of Orteronel (TAK-700)—an Investigational 17,20-Lyase Inhibitor—in Patients with Metastatic Castration-Resistant Prostate Cancer
- (2014) Robert Dreicer et al. CLINICAL CANCER RESEARCH
- Aggressive Variants of Castration-Resistant Prostate Cancer
- (2014) H. Beltran et al. CLINICAL CANCER RESEARCH
- Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma
- (2014) Yanyan Li et al. IUBMB LIFE
- Cabozantinib in Chemotherapy-Pretreated Metastatic Castration-Resistant Prostate Cancer: Results of a Phase II Nonrandomized Expansion Study
- (2014) Matthew R. Smith et al. JOURNAL OF CLINICAL ONCOLOGY
- Cyr61 promotes epithelial-mesenchymal transition and tumor metastasis of osteosarcoma by Raf-1/MEK/ERK/Elk-1/TWIST-1 signaling pathway
- (2014) Chun-Han Hou et al. Molecular Cancer
- Epithelial-to-Mesenchymal Transition Mediates Docetaxel Resistance and High Risk of Relapse in Prostate Cancer
- (2014) M. Marin-Aguilera et al. MOLECULAR CANCER THERAPEUTICS
- Brachyury—a biomarker for progression and prognosis?
- (2014) Clemens Thoma Nature Reviews Urology
- Epithelial plasticity in prostate cancer: principles and clinical perspectives
- (2014) Rajdeep Das et al. TRENDS IN MOLECULAR MEDICINE
- High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development
- (2013) D. Lin et al. CANCER RESEARCH
- Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation
- (2013) Kouji Izumi et al. EMBO Molecular Medicine
- IGF2 increases de novo steroidogenesis in prostate cancer cells
- (2013) Amy A Lubik et al. ENDOCRINE-RELATED CANCER
- EAU Guidelines on Prostate Cancer. Part II: Treatment of Advanced, Relapsing, and Castration-Resistant Prostate Cancer
- (2013) Axel Heidenreich et al. EUROPEAN UROLOGY
- Differential Androgen Deprivation Therapies with Anti-androgens Casodex/Bicalutamide or MDV3100/EnzalutamideversusAnti-androgen Receptor ASC-J9® Lead to PromotionversusSuppression of Prostate Cancer Metastasis
- (2013) Tzu-Hua Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase I Study of ARN-509, a Novel Antiandrogen, in the Treatment of Castration-Resistant Prostate Cancer
- (2013) Dana E. Rathkopf et al. JOURNAL OF CLINICAL ONCOLOGY
- Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC)
- (2013) Eva Karamitopoulou et al. Journal of Translational Medicine
- The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells
- (2013) A B D'Assoro et al. ONCOGENE
- AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells
- (2013) M K Asiedu et al. ONCOGENE
- Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling
- (2013) T-H Lin et al. Cell Death & Disease
- A Clinically Relevant Androgen Receptor Mutation Confers Resistance to Second-Generation Antiandrogens Enzalutamide and ARN-509
- (2013) J. D. Joseph et al. Cancer Discovery
- Antiangiogenic Drugs and Tyrosine Kinases
- (2012) Jozsef Timar et al. Anti-Cancer Agents in Medicinal Chemistry
- Targeting the androgen receptor signalling axis in castration-resistant prostate cancer (CRPC)
- (2012) Che-Kai Tsao et al. BJU INTERNATIONAL
- The T-box transcription factor Brachyury regulates epithelial–mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells
- (2012) Miyuki Shimoda et al. BMC CANCER
- Brachyury, a Driver of the Epithelial-Mesenchymal Transition, Is Overexpressed in Human Lung Tumors: An Opportunity for Novel Interventions against Lung Cancer
- (2012) M. Roselli et al. CLINICAL CANCER RESEARCH
- T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma
- (2012) IKUMI IMAJYO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Indoxyl sulfate-induced epithelial-to-mesenchymal transition and apoptosis of renal tubular cells as novel mechanisms of progression of renal disease
- (2012) Su Hyun Kim et al. LABORATORY INVESTIGATION
- The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target
- (2012) J D Paccez et al. ONCOGENE
- Genome-Wide Analysis of Androgen Receptor Targets Reveals COUP-TF1 as a Novel Player in Human Prostate Cancer
- (2012) Ruth Perets et al. PLoS One
- Epithelial mesenchymal transition in colorectal cancer: Seminal role in promoting disease progression and resistance to neoadjuvant therapy
- (2012) Aneel Bhangu et al. SURGICAL ONCOLOGY-OXFORD
- Androgen Deprivation Causes Epithelial-Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy
- (2011) Y. Sun et al. CANCER RESEARCH
- IL-8 Signaling Plays a Critical Role in the Epithelial-Mesenchymal Transition of Human Carcinoma Cells
- (2011) R. I. Fernando et al. CANCER RESEARCH
- The Raf/MEK/extracellular signal-regulated kinase 1/2 pathway can mediate growth inhibitory and differentiation signaling via androgen receptor downregulation in prostate cancer cells
- (2011) Seung-Keun Hong et al. EXPERIMENTAL CELL RESEARCH
- ERG gene rearrangements are common in prostatic small cell carcinomas
- (2011) Tamara L Lotan et al. MODERN PATHOLOGY
- ERG–TMPRSS2 rearrangement is shared by concurrent prostatic adenocarcinoma and prostatic small cell carcinoma and absent in small cell carcinoma of the urinary bladder: evidence supporting monoclonal origin
- (2011) Sean R Williamson et al. MODERN PATHOLOGY
- Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth
- (2011) F. M. Yakes et al. MOLECULAR CANCER THERAPEUTICS
- Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
- (2011) H. Beltran et al. Cancer Discovery
- Cancer Statistics, 2010
- (2010) A. Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
- (2010) S. J. Holland et al. CANCER RESEARCH
- The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells
- (2010) Romaine I. Fernando et al. JOURNAL OF CLINICAL INVESTIGATION
- An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies
- (2010) X Ye et al. ONCOGENE
- Snail transcription factor regulates neuroendocrine differentiation in LNCaP prostate cancer cells
- (2010) Danielle McKeithen et al. PROSTATE
- Bi-directional activation between mesenchymal stem cells and CLL B-cells: implication for CLL disease progression
- (2009) Wei Ding et al. BRITISH JOURNAL OF HAEMATOLOGY
- Increased Expression of Androgen Receptor Sensitizes Prostate Cancer Cells to Low Levels of Androgens
- (2009) K. K. Waltering et al. CANCER RESEARCH
- Castration-Resistant Prostate Cancer: Locking Up the Molecular Escape Routes
- (2009) R. M. Attar et al. CLINICAL CANCER RESEARCH
- Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-α expression
- (2009) Jiann-Jyh Lai et al. JOURNAL OF CLINICAL INVESTIGATION
- Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients
- (2009) Philippe O. Gannon et al. JOURNAL OF IMMUNOLOGICAL METHODS
- SharedTP53gene mutation in morphologically and phenotypically distinct concurrent primary small cell neuroendocrine carcinoma and adenocarcinoma of the prostate
- (2009) Donna E. Hansel et al. PROSTATE
- Receptor tyrosine kinase inhibitors in thyroid cancer
- (2008) Maria Domenica Castellone et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance
- (2008) S. M. Dehm et al. CANCER RESEARCH
- AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression
- (2008) Y.-X. Zhang et al. CANCER RESEARCH
- Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer
- (2008) J. A. Locke et al. CANCER RESEARCH
- Inhibition of Aurora-A suppresses epithelial–mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells
- (2008) Xiang-Bo Wan et al. CARCINOGENESIS
- EMT and MET in carcinoma—clinical observations, regulatory pathways and new models
- (2008) Erik W. Thompson et al. CLINICAL & EXPERIMENTAL METASTASIS
- Mechanisms of Disease: epithelial–mesenchymal transition—does cellular plasticity fuel neoplastic progression?
- (2008) Eva A Turley et al. Nature clinical practice. Oncology
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now