Putative oncogeneBrachyury(T) is essential to specify cell fate but dispensable for notochord progenitor proliferation and EMT

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics

(2015) C. Kadoch et al.   Science Advances

Nature and extent of left/right axis defects inTWis/TWismutant mouse embryos

(2014) Daniel Concepcion et al.   DEVELOPMENTAL DYNAMICS

Characterization of T gene sequence variants and germline duplications in familial and sporadic chordoma

(2014) Michael J. Kelley et al.   HUMAN GENETICS

Generation of knock-in mice that express nuclear enhanced green fluorescent protein and tamoxifen-inducible Cre recombinase in the notochord fromFoxa2andTloci

(2013) Yu Imuta et al.   GENESIS

Foxa1 and Foxa2 Are Required for Formation of the Intervertebral Discs

(2013) Jennifer A. Maier et al.   PLoS One

The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies

(2013) B Huang et al.   Cell Death & Disease

From Notochord Formation to Hereditary Chordoma: The Many Roles ofBrachyury

(2013) Yutaka Nibu et al.   Biomed Research International

In vivo knockdown of Brachyury results in skeletal defects and urorectal malformations resembling caudal regression syndrome

(2012) Tracie Pennimpede et al.   DEVELOPMENTAL BIOLOGY

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Cancer Vaccines Targeting the Epithelial-Mesenchymal Transition: Tissue Distribution of Brachyury and Other Drivers of the Mesenchymal-Like Phenotype of Carcinomas

(2012) Duane H. Hamilton et al.   SEMINARS IN ONCOLOGY

Strategies to target molecules that control the acquisition of a mesenchymal-like phenotype by carcinoma cells

(2011) Claudia Palena et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs

(2011) K.-S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward an understanding of the role of notochordal cells in the adult intervertebral disc: From discord to accord

(2010) Makarand V. Risbud et al.   DEVELOPMENTAL DYNAMICS

The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells

(2010) Romaine I. Fernando et al.   JOURNAL OF CLINICAL INVESTIGATION

T (brachyury) gene duplication confers major susceptibility to familial chordoma

(2009) Xiaohong R Yang et al.   NATURE GENETICS

Abnormal Placental Development and Early Embryonic Lethality in EpCAM-Null Mice

(2009) Keisuke Nagao et al.   PLoS One

Uncoupling Sonic Hedgehog Control of Pattern and Expansion of the Developing Limb Bud

(2008) Jianjian Zhu et al.   DEVELOPMENTAL CELL

Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: Implications for disk degeneration and chordoma formation

(2008) Kyung-Suk Choi et al.   DEVELOPMENTAL DYNAMICS

A mouse line expressing Foxa2-driven Cre recombinase in node, notochord, floorplate, and endoderm

(2008) Lena Uetzmann et al.   GENESIS