Nanoparticle-based thymulin gene therapy therapeutically reverses key pathology of experimental allergic asthma

Steroid-Resistant Asthma and Neutrophils

(2020) Takeshi Nabe   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Harmonized Outcome Measures for Use in Asthma Patient Registries and Clinical Practice

(2019) Richard E. Gliklich et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sevoflurane Prevents Airway Remodeling via Downregulation of VEGF and TGF-β1 in Mice with OVA-Induced Chronic Airway Inflammation

(2019) Qi-Ying Shen et al.   INFLAMMATION

Engineered ovalbumin-expressing regulatory T cells protect against anaphylaxis in ovalbumin-sensitized mice

(2019) Maha Abdeladhim et al.   CLINICAL IMMUNOLOGY

Beta-2 adrenergic receptors increase TREG cell suppression in an OVA-induced allergic asthma mouse model when mice are moderate aerobically exercised

(2018) Kari J. Dugger et al.   BMC IMMUNOLOGY

Uncontrolled asthmatics have increased FceRI+ and TGF-β-positive MCTC mast cells and collagen VI in the alveolar parenchyma

(2018) C. K. Andersson et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Role of Human Macrophage Polarization in Inflammation during Infectious Diseases

(2018) Chiraz Atri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of beta-agonists on LAM progression and treatment

(2018) Kang Le et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage polarization and allergic asthma

(2018) Arjun Saradna et al.   Translational Research

Airway smooth muscle may drive mucus hypersecretion in asthma

(2018) James G. Martin   EUROPEAN RESPIRATORY JOURNAL

The Role of Neutrophils in Asthma

(2018) Reynold A. Panettieri   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Mast Cell-Mediated Orchestration of the Immune Responses in Human Allergic Asthma: Current Insights

(2018) Daniel Elieh Ali Komi et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Extrathymic production of thymulin induced by oxidative stress, heat shock, apoptosis, or necrosis

(2017) Sergey M Lunin et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

(2017) Craig S. Schneider et al.   Science Advances

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma

(2016) Marrah E. Lachowicz-Scroggins et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Alternative Macrophage Activation Is Increased in Asthma

(2016) Pierre-Olivier Girodet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Roxithromycin inhibits VEGF-induced human airway smooth muscle cell proliferation: Opportunities for the treatment of asthma

(2016) Qing-Mei Pei et al.   EXPERIMENTAL CELL RESEARCH

Comparison of diagnostic validity of mannitol and methacholine challenges and relationship to clinical status and airway inflammation in steroid-naïve asthmatic patients

(2016) Konstantinos Porpodis et al.   JOURNAL OF ASTHMA

Barriers to inhaled gene therapy of obstructive lung diseases: A review

(2016) Namho Kim et al.   JOURNAL OF CONTROLLED RELEASE

The Mucus Barrier to Inhaled Gene Therapy

(2016) Gregg A Duncan et al.   MOLECULAR THERAPY

Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy

(2015) Panagiotis Mastorakos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma

(2014) Adriana L. da Silva et al.   JOURNAL OF CONTROLLED RELEASE

CXCL1 is a negative regulator of mast cell chemotaxis to airway smooth muscle cell productsin vitro

(2013) H. Alkhouri et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Targeting eosinophils in allergy, inflammation and beyond

(2013) Patricia C. Fulkerson et al.   NATURE REVIEWS DRUG DISCOVERY

Impact of Bacillus Calmette–Guérin Moreau vaccine on lung remodeling in experimental asthma

(2013) Cynthia dos Santos Samary et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Decreased CTLA4+ and Foxp3+ CD25highCD4+ Cells in Induced Sputum from Patients with Mild Atopic Asthma

(2013) Tomotaka Kawayama et al.   ALLERGOLOGY INTERNATIONAL

The C-C motif chemokine ligands CCL5, CCL11 and CCL24 induce the migration of circulating fibrocytes from patients with severe asthma

(2012) M Isgrò et al.   Mucosal Immunology

Epithelial eotaxin-2 and eotaxin-3 expression: relation to asthma severity, luminal eosinophilia and age at onset

(2012) John M Coleman et al.   THORAX

Gene Therapy for Allergic Airway Diseases

(2011) Tania Maes et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Thymus peptides regulate activity of RAW 264.7 macrophage cells: inhibitory analysis and a role of signal cascades

(2011) Sergey M. Lunin et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Lidocaine-derivative JMF2-1 prevents ovalbumin-induced airway inflammation by regulating the function and survival of T cells

(2010) P. C. Olsen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Sex-specific lung remodeling and inflammation changes in experimental allergic asthma

(2010) Mariana A. Antunes et al.   JOURNAL OF APPLIED PHYSIOLOGY

Effects of bone marrow-derived mononuclear cells on airway and lung parenchyma remodeling in a murine model of chronic allergic inflammation

(2010) Soraia C. Abreu et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Regulatory T Cells in Asthma

(2009) Clare M. Lloyd et al.   IMMUNITY

The role of the extracellular matrix and specific growth factors in the regulation of inflammation and remodelling in asthma

(2009) Janette K. Burgess   PHARMACOLOGY & THERAPEUTICS

Thymulin, A Thymic Peptide, Prevents the Overproduction of Pro-Inflammatory Cytokines and Heat Shock Protein Hsp70 in Inflammation-Bearing Mice

(2008) S. M. Lunin et al.   IMMUNOLOGICAL INVESTIGATIONS