Role of Human Macrophage Polarization in Inflammation during Infectious Diseases

Whole transcriptome analysis reveals differential gene expression profile reflecting macrophage polarization in response to influenza A H5N1 virus infection

(2018) Na Zhang et al.   BMC Medical Genomics

Modulation of human macrophage activity by Ascaris antigens is dependent on macrophage polarization state

(2018) Sara Almeida et al.   IMMUNOBIOLOGY

M1 and M2 Monocytes in Rheumatoid Arthritis: A Contribution of Imbalance of M1/M2 Monocytes to Osteoclastogenesis

(2018) Shoichi Fukui et al.   Frontiers in Immunology

Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid-derived suppressor cells from human blood and bone marrow

(2017) Mikael Roussel et al.   JOURNAL OF LEUKOCYTE BIOLOGY

THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro

(2017) Hiromi Shiratori et al.   MOLECULAR IMMUNOLOGY

DHRS9 Is a Stable Marker of Human Regulatory Macrophages

(2017) Paloma Riquelme et al.   TRANSPLANTATION

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s)

(2017) Fei Guo et al.   XENOTRANSPLANTATION

Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions

(2017) Jeanette Wagener et al.   mBio

Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype

(2017) Fanping Kong et al.   PLoS Pathogens

Glycolytic pathway affects differentiation of human monocytes to regulatory macrophages

(2016) Hiroaki Suzuki et al.   IMMUNOLOGY LETTERS

p21 mediates macrophage reprogramming through regulation of p50-p50 NF-κB and IFN-β

(2016) Gorjana Rackov et al.   JOURNAL OF CLINICAL INVESTIGATION

Pro- and anti-inflammatory cytokines in cutaneous leishmaniasis: a review

(2016) Nahid Maspi et al.   Pathogens and Global Health

Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella

(2016) Antoine-Emmanuel Saliba et al.   Nature Microbiology

HCV core protein inhibits polarization and activity of both M1 and M2 macrophages through the TLR2 signaling pathway

(2016) Qianqian Zhang et al.   Scientific Reports

Phenotypic, Functional, and Plasticity Features of Classical and Alternatively Activated Human Macrophages

(2015) Abdullah A. Tarique et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Variations in genes regulating tumor-associated macrophages (TAMs) to predict outcomes of bevacizumab-based treatment in patients with metastatic colorectal cancer: results from TRIBE and FIRE3 trials

(2015) Y. Sunakawa et al.   ANNALS OF ONCOLOGY

M2 Polarization of Monocytes-Macrophages Is a Hallmark of Indian Post Kala-Azar Dermal Leishmaniasis

(2015) Debanjan Mukhopadhyay et al.   PLoS Neglected Tropical Diseases

Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro

(2015) Zikun Huang et al.   PLoS One

Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression

(2015) Ang Yuan et al.   Scientific Reports

Human macrophage polarization in vitro: Maturation and activation methods compared

(2014) Daphne Y.S. Vogel et al.   IMMUNOBIOLOGY

CXCL4-induced plaque macrophages can be specifically identified by co-expression of MMP7+S100A8+in vitro and in vivo

(2014) Christian Erbel et al.   Innate Immunity

Macrophage Polarization in Inflammatory Diseases

(2014) Yan-Cun Liu et al.   International Journal of Biological Sciences

Transcriptome Analysis Reveals Human Cytomegalovirus Reprograms Monocyte Differentiation toward an M1 Macrophage

(2014) G. Chan et al.   JOURNAL OF IMMUNOLOGY

Different Subsets of Macrophages in Patients with New Onset Tuberculous Pleural Effusion

(2014) Ying Tang et al.   PLoS One

Transcriptomic Profiling of the Development of the Inflammatory Response in Human Monocytes In Vitro

(2014) Paola Italiani et al.   PLoS One

Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response toCandida albicans

(2014) Jose Antonio Reales-Calderón et al.   PROTEOMICS

Th1/Th2 Paradigm Extended: Macrophage Polarization as an Unappreciated Pathogen-Driven Escape Mechanism?

(2014) Eric Muraille et al.   Frontiers in Immunology

Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin

(2013) Marie Jaguin et al.   CELLULAR IMMUNOLOGY

HumanIL10Gene Repression by Rev-erbα AmelioratesMycobacterium tuberculosisClearance

(2013) Vemika Chandra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

(2013) Daphne YS Vogel et al.   Journal of Neuroinflammation

Human Cytomegalovirus Interleukin-10 Polarizes Monocytes toward a Deactivated M2c Phenotype To Repress Host Immune Responses

(2013) S. Avdic et al.   JOURNAL OF VIROLOGY

Macrophage Polarisation: an Immunohistochemical Approach for Identifying M1 and M2 Macrophages

(2013) Mário Henrique M. Barros et al.   PLoS One

CMV Late Phase-Induced mTOR Activation Is Essential for Efficient Virus Replication in Polarized Human Macrophages

(2012) M. Poglitsch et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Host Responses in Tissue Repair and Fibrosis

(2012) Jeremy S. Duffield et al.   Annual Review of Pathology-Mechanisms of Disease

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Comparative Analysis of the Interaction of Helicobacter pylori with Human Dendritic Cells, Macrophages, and Monocytes

(2012) Michael Fehlings et al.   INFECTION AND IMMUNITY

Tumor-associated macrophages promote angiogenesis and lymphangiogenesis of gastric cancer

(2012) Hui Wu et al.   JOURNAL OF SURGICAL ONCOLOGY

Human Cytomegalovirus Stimulates Monocyte-to-Macrophage Differentiation via the Temporal Regulation of Caspase 3

(2012) G. Chan et al.   JOURNAL OF VIROLOGY

Reversible differentiation of pro- and anti-inflammatory macrophages

(2012) Wei Xu et al.   MOLECULAR IMMUNOLOGY

Influenza Virus A Infection of Human Monocyte and Macrophage Subpopulations Reveals Increased Susceptibility Associated with Cell Differentiation

(2012) Marieke A. Hoeve et al.   PLoS One

High-Resolution Transcriptome of Human Macrophages

(2012) Marc Beyer et al.   PLoS One

Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis

(2012) Carmen A Ambarus et al.   ARTHRITIS RESEARCH & THERAPY

The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response

(2012) Dong Liu et al.   Frontiers in Cellular and Infection Microbiology

Carcinoma origin dictates differential skewing of monocyte function

(2012) Marijn Bögels et al.   OncoImmunology

Activating Transcription Factor 1 Directs Mhem Atheroprotective Macrophages Through Coordinated Iron Handling and Foam Cell Protection

(2011) Joseph J. Boyle et al.   CIRCULATION RESEARCH

M2-Polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma

(2011) Bicheng Zhang et al.   Clinics

The chemokine CCL18 causes maturation of cultured monocytes to macrophages in the M2 spectrum

(2011) Ingrid U. Schraufstatter et al.   IMMUNOLOGY

Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

(2011) J. A. Hutchinson et al.   JOURNAL OF IMMUNOLOGY

Early IL-10 predominant responses are associated with progression to chronic hepatitis C virus infection in injecting drug users

(2010) J. K. Flynn et al.   JOURNAL OF VIRAL HEPATITIS

Leishmania-induced repression of selected non-coding RNA genes containing B-box element at their promoters in alternatively polarized M2 macrophages

(2010) Anitra L. Farrow et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Enhanced M1 Macrophage Polarization in Human Helicobacter pylori-Associated Atrophic Gastritis and in Vaccinated Mice

(2010) Marianne Quiding-Järbrink et al.   PLoS One

The macrophage in HIV-1 infection: From activation to deactivation?

(2010) Georges Herbein et al.   Retrovirology

Coronary Intraplaque Hemorrhage Evokes a Novel Atheroprotective Macrophage Phenotype

(2009) Joseph J. Boyle et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

(2009) M. A. Brockman et al.   BLOOD

Alveolar macrophages in allergic asthma: An expression signature characterized by heat shock protein pathways

(2009) Anne-Marie Madore et al.   HUMAN IMMUNOLOGY

M1 and M2a Polarization of Human Monocyte-Derived Macrophages Inhibits HIV-1 Replication by Distinct Mechanisms

(2009) Edana Cassol et al.   JOURNAL OF IMMUNOLOGY

Smoking-Dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of Chronic Obstructive Pulmonary Disease

(2009) R. Shaykhiev et al.   JOURNAL OF IMMUNOLOGY

Macrophage polarization and HIV-1 infection

(2009) Edana Cassol et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Transcriptional response in the peripheral blood of patients infected with Salmonella enterica serovar Typhi

(2009) Lucinda J. Thompson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Simultaneous gene expression profiling in human macrophages infected with Leishmania major parasites using SAGE

(2008) Fatma Z Guerfali et al.   BMC GENOMICS

Metchnikoff's Legacy in 2008

(2008) Carl Nathan   NATURE IMMUNOLOGY

Macrophage activation by endogenous danger signals

(2007) X Zhang et al.   JOURNAL OF PATHOLOGY