Alternative Macrophage Activation Is Increased in Asthma

Phenotypic, Functional, and Plasticity Features of Classical and Alternatively Activated Human Macrophages

(2015) Abdullah A. Tarique et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Recruited Alveolar Macrophages, in Response to Airway Epithelial–Derived Monocyte Chemoattractant Protein 1/CCL2, Regulate Airway Inflammation and Remodeling in Allergic Asthma

(2015) Yong Gyu Lee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Impact of endobronchial allergen provocation on macrophage phenotype in asthmatics

(2014) Carla Winkler et al.   BMC IMMUNOLOGY

In Vivo Characterization of Alveolar and Interstitial Lung Macrophages in Rhesus Macaques: Implications for Understanding Lung Disease in Humans

(2014) Y. Cai et al.   JOURNAL OF IMMUNOLOGY

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

(2014) Jan Mauer et al.   NATURE IMMUNOLOGY

FcεRI stimulation promotes the differentiation of histamine receptor 1-expressing inflammatory macrophages

(2013) N. Novak et al.   ALLERGY

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

(2013) F. O. Martinez et al.   BLOOD

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

(2013) Ari B. Molofsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammatory Responses Induced by Lipopolysaccharide Are Amplified in Primary Human Monocytes but Suppressed in Macrophages by Complement Protein C5a

(2013) V. Seow et al.   JOURNAL OF IMMUNOLOGY

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

(2013) Takashi Satoh et al.   NATURE

Dupilumab in Persistent Asthma with Elevated Eosinophil Levels

(2013) Sally Wenzel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Macrophages as IL-25/IL-33-Responsive Cells Play an Important Role in the Induction of Type 2 Immunity

(2013) Zhonghan Yang et al.   PLoS One

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation

(2012) Andrew Q Ford et al.   BMC IMMUNOLOGY

Phenotypic characterization of lung macrophages in asthmatic patients: Overexpression of CCL17

(2012) Karl J. Staples et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens

(2012) Michael J. Holtzman   JOURNAL OF CLINICAL INVESTIGATION

Emerging roles of pulmonary macrophages in driving the development of severe asthma

(2012) M. Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Type II-Activated Murine Macrophages Produce IL-4

(2012) Anne Camille La Flamme et al.   PLoS One

Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs

(2011) J. Van den Bossche et al.   BLOOD

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

More alternative activation of macrophages in lungs of asthmatic patients

(2010) Barbro N. Melgert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Sputum IL-6 concentrations in severe asthma and its relationship with FEV1

(2010) J. B. Morjaria et al.   THORAX

Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes

(2009) J. Van den Bossche et al.   BLOOD

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

(2009) Denis Bedoret et al.   JOURNAL OF CLINICAL INVESTIGATION

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

CD1a expression defines an interleukin-12 producing population of human dendritic cells

(2008) M. Cernadas et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

(2008) Edy Y Kim et al.   NATURE MEDICINE

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines

(2008) Robin L. Thurmond et al.   NATURE REVIEWS DRUG DISCOVERY

Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma

(2008) P Bhavsar et al.   THORAX