Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/γ-secretase at the cell surface
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Title
Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/γ-secretase at the cell surface
Authors
Keywords
-
Journal
eLife
Volume 9, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2020-06-30
DOI
10.7554/elife.56679
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Note: Only part of the references are listed.- A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor
- (2019) Lei Liu et al. JOURNAL OF CELL BIOLOGY
- Recognition of the amyloid precursor protein by human γ-secretase
- (2019) Rui Zhou et al. SCIENCE
- Rhomboid distorts lipids to break the viscosity-imposed speed limit of membrane diffusion
- (2019) Alex J. B. Kreutzberger et al. SCIENCE
- Uncovering the Binding Mode of γ -Secretase Inhibitors
- (2019) Manuel Hitzenberger et al. ACS Chemical Neuroscience
- Structure and Function of the γ-Secretase Complex
- (2019) Michael S. Wolfe BIOCHEMISTRY
- Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines
- (2019) Pranesh Padmanabhan et al. eLife
- Simulating the γ-secretase enzyme: Recent advances and future directions
- (2018) Rodrigo Aguayo-Ortiz et al. BIOCHIMIE
- Modulation of γ- and β-Secretases as Early Prevention Against Alzheimer’s Disease
- (2018) Iryna Voytyuk et al. BIOLOGICAL PSYCHIATRY
- Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
- (2018) Spencer A. Freeman et al. CELL
- Mapping molecular assemblies with fluorescence microscopy and object-based spatial statistics
- (2018) Thibault Lagache et al. Nature Communications
- Steric exclusion and protein conformation determine the localization of plasma membrane transporters
- (2018) Frans Bianchi et al. Nature Communications
- The Many Substrates of Presenilin/γ-Secretase
- (2018) Annakaisa Haapasalo et al. JOURNAL OF ALZHEIMERS DISEASE
- Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function
- (2018) Laura Martínez-Muñoz et al. MOLECULAR CELL
- Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane
- (2018) Mingguang Wang et al. NEUROSCIENCE LETTERS
- Single molecule localization microscopy coupled with touch preparation for the quantification of trastuzumab-bound HER2
- (2018) Steven J. Tobin et al. Scientific Reports
- Structural basis of Notch recognition by human γ-secretase
- (2018) Guanghui Yang et al. NATURE
- Super-resolution microscopy demystified
- (2018) Lothar Schermelleh et al. NATURE CELL BIOLOGY
- Turning single-molecule localization microscopy into a quantitative bioanalytical tool
- (2017) Philip R Nicovich et al. Nature Protocols
- Time-resolved molecule counting by photon statistics across the visible spectrum
- (2017) K. S. Grußmayer et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters
- (2017) Adekunle T. Bademosi et al. Nature Communications
- PhotoGate microscopy to track single molecules in crowded environments
- (2017) Vladislav Belyy et al. Nature Communications
- A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency
- (2017) Arun Kumar Tharkeshwar et al. Scientific Reports
- Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool
- (2016) Ragna Sannerud et al. CELL
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- Inhomogeneity Based Characterization of Distribution Patterns on the Plasma Membrane
- (2016) Laura Paparelli et al. PLoS Computational Biology
- Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis
- (2015) Allen C. Chen et al. JOURNAL OF CELL BIOLOGY
- An atomic structure of human γ-secretase
- (2015) Xiao-chen Bai et al. NATURE
- SR-Tesseler: a method to segment and quantify localization-based super-resolution microscopy data
- (2015) Florian Levet et al. NATURE METHODS
- Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway
- (2015) Utpal Das et al. NATURE NEUROSCIENCE
- Glutamate-Induced AMPA Receptor Desensitization Increases Their Mobility and Modulates Short-Term Plasticity through Unbinding from Stargazin
- (2015) Audrey Constals et al. NEURON
- Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1
- (2015) Ljiljana Milenkovic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A review of progress in single particle tracking: from methods to biophysical insights
- (2015) Carlo Manzo et al. REPORTS ON PROGRESS IN PHYSICS
- Mapping molecules in scanning far-field fluorescence nanoscopy
- (2015) Haisen Ta et al. Nature Communications
- The tetraspanin web revisited by super-resolution microscopy
- (2015) Malou Zuidscherwoude et al. Scientific Reports
- Sampling the conformational space of the catalytic subunit of human γ-secretase
- (2015) Xiao-chen Bai et al. eLife
- Targeting the γ-/β-secretase interaction reduces β-amyloid generation and ameliorates Alzheimer’s disease-related pathogenesis
- (2015) Jin Cui et al. Cell Discovery
- ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging
- (2014) Martin Ovesný et al. BIOINFORMATICS
- Deciphering the Subunit Composition of Multimeric Proteins by Counting Photobleaching Steps
- (2014) Ryan J. Arant et al. CHEMPHYSCHEM
- High-density single-particle tracking: quantifying molecule organization and dynamics at the nanoscale
- (2014) Jean-Baptiste Sibarita HISTOCHEMISTRY AND CELL BIOLOGY
- The dynamic conformational landscape of -secretase
- (2014) N. Elad et al. JOURNAL OF CELL SCIENCE
- A fast growing spectrum of biological functions of γ-secretase in development and disease
- (2013) Nathalie Jurisch-Yaksi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Interactome Analyses of Mature γ-Secretase Complexes Reveal Distinct Molecular Environments of Presenilin (PS) Paralogs and Preferential Binding of Signal Peptide Peptidase to PS2
- (2013) Amy Hye Won Jeon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Super-Resolution Imaging Reveals That AMPA Receptors Inside Synapses Are Dynamically Organized in Nanodomains Regulated by PSD95
- (2013) D. Nair et al. JOURNAL OF NEUROSCIENCE
- Real-Time Analysis and Visualization for Single-Molecule Based Super-Resolution Microscopy
- (2013) Adel Kechkar et al. PLoS One
- AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting
- (2013) P. Hastie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Localizer: fast, accurate, open-source, and modular software package for superresolution microscopy
- (2012) Peter Dedecker et al. JOURNAL OF BIOMEDICAL OPTICS
- Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions
- (2012) Olivier Rossier et al. NATURE CELL BIOLOGY
- Transient GPI-anchored protein homodimers are units for raft organization and function
- (2012) Kenichi G N Suzuki et al. Nature Chemical Biology
- Synchronization of secretory protein traffic in populations of cells
- (2012) Gaelle Boncompain et al. NATURE METHODS
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Wavelet analysis for single molecule localization microscopy
- (2012) I. Izeddin et al. OPTICS EXPRESS
- Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization
- (2012) D. Calebiro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1
- (2011) R. Sannerud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel Research Horizons for Presenilins and γ-Secretases in Cell Biology and Disease
- (2010) Bart De Strooper et al. Annual Review of Cell and Developmental Biology
- Resting State Orai1 Diffuses as Homotetramer in the Plasma Membrane of Live Mammalian Cells
- (2010) Josef Madl et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stoichiometry of the KCNQ1 - KCNE1 ion channel complex
- (2010) K. Nakajo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ADAM10, the Rate-limiting Protease of Regulated Intramembrane Proteolysis of Notch and Other Proteins, Is Processed by ADAMS-9, ADAMS-15, and the γ-Secretase
- (2009) Thomas Tousseyn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Analysis of the γ-secretase interactome and validation of its association with tetraspanin-enriched microdomains
- (2009) Tomoko Wakabayashi et al. NATURE CELL BIOLOGY
- Enzymatic assembly of DNA molecules up to several hundred kilobases
- (2009) Daniel G Gibson et al. NATURE METHODS
- Active γ-secretase is localized to detergent-resistant membranes in human brain
- (2008) Ji-Yeun Hur et al. FEBS Journal
- Glu332in the Nicastrin Ectodomain Is Essential for γ-Secretase Complex Maturation but Not for Its Activity
- (2008) Lucía Chávez-Gutiérrez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High-density mapping of single-molecule trajectories with photoactivated localization microscopy
- (2008) Suliana Manley et al. NATURE METHODS
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